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The Indonesian Journal of Dental Research
Published by Universitas Gadjah Mada
ISSN : -     EISSN : -     DOI : -
Core Subject : Health,
Dentistry
Arjuna Subject : -
Articles 10 Documents
 1 
Search results for , issue " Proceeding Book" : 10 Documents clear
Review: Pyridinoline Cross Link as Biomarker Alveolar Bone Destruction Dharmayanti, Agustin Wulan Suci
The Indonesian Journal of Dental Research Proceeding Book
Publisher : The Indonesian Journal of Dental Research

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Abstract

Background: In Indonesia, prevalence of periodontal diseases was very high about 46 %. Periodontal diseases caused alveolar bone destruction. When bacteria attacked, bacteria product and host response stimulate collagen degradation, especially type 1 collagen. Collagen type 1 consisted pyridinoline cross link. Collagen degradation product will be excreted in bloodstream and urine. These products have advantage to detect alveolar bone destruction in periodontal disease early, because clinical and rongentnologis examination can detect advanced stage of alveolar bone destruction in periodontal diseases. Objective: The aim of this review was to know pyridinoline cross link as biomarker alveolar bone destruction. Literature review: Alveolar bone tissue was mineralization connective tissue. Alveolar bone can be destructed by dental plaque bacteria and also by host response. Dental plaque bacteria stimulated PMN and MMP releasing at inflamed gingival area. They caused collagen fibers of alveolar bone was degradated and caused releasing of pyridinoline crosslink in blood. Conclusion: Pyridinoline crosslink can be used as biomarker of alveolar bone destruction.
Micronucleus frequency of the buccal epithelial cells on pesticide-exposed female farmers in Dieng village, Central Java Yudasari, Innayati Oktiana; Susilowati, Heni; Jonarta, Alma Linggar
The Indonesian Journal of Dental Research Proceeding Book
Publisher : The Indonesian Journal of Dental Research

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Abstract

Pesticide is a toxic material used to eradicate physical intruder of crop, including pests, diseases, or weeds. Long-term exposure of pesticide to human body may give genotoxic effects at cellular level, as its substances are chemically bond with the components of DNA triggering the damage of DNA and chromosomes. Micronucleus, additional nucleus on the cells, presents as a result of the termination of the chemical bonds of DNA. The aim of this study was to investigate the frequency of micronuclei of buccal epithelial cells on pesticide-exposed female farmers in Dieng Village, Central Java. This research was conducted on 36 female villagers of Dieng Plateau. The first group consisted of 18 subjects who had regularly and directly exposed by pesticides due to their job as farmers. The control group consisted of 18 subjects were unexposed to pesticides. Buccal epithelium cells of all subjects was collected by swabing the right and left buccal mucosa using cytobrush, fixed and stained using Feulgen-Rossenbeck method. The micronuclei frequency was counted per 1000 epithelial cells. Data was analyzed using Independent Sample t-test. The statistical analysis showed a significant difference between exposed and unexposed groups (p= 0,01). It is concluded that there was an increase in the micronucleus frequency of buccal epithelial cells on pesticide-exposed female farmers in Dieng Village. Moreover, direct long-term exposure of pesticides may harm and damage the human body cells at the gene level.
The Effect of Wear Particles from Joint Prostheses Materials to Bone Cells Number Suhartini, Suhartini
The Indonesian Journal of Dental Research Proceeding Book
Publisher : The Indonesian Journal of Dental Research

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Abstract

Background: The wear particles of joint prostheses can induce releasing of inflammatory mediators. Releasing of inflammatory mediators from activated inflammatory cells can lead bone cells respons. Methods: Wear particles generated by wear testing of both materials Ultra High Molecular Weight Polyethylene (UHMWPE) GUR 1120 and Stainless Steel 316 L with ion implantation by using pin on plate unidirectional motion machine and phosphate buffer saline (PBS) as lubricant. The velocity of running wear test is 116.5 mm/s and the sliding distance was 30 km. Furthermore, wear particles was inserted into knee joint synovium capsule of Rattus norvegicus sp. The animals were sacrificed to know the number bone cells on seventh day. Results: Statistical analysis by Kruskal Wallis showed that there was no significant differences in the number of osteoblast cells (p=0.094) and there were no significant differences in the number of osteoclast cells (p=0.143). Conclusion: There was no effect of wear particles from joint prosthesesto bone cells number
The Noteworthy Case: Atypical Palatal Ulcer Which is Progressivelly Develop to Oral Squamous Cell Carcinoma in Diabetic Elderly Prayudha, Satrya Ayu E.; Chrismawaty, B. Esti; Agustina, Dewi; Subagyo, Goeno
The Indonesian Journal of Dental Research Proceeding Book
Publisher : The Indonesian Journal of Dental Research

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Abstract

Background: Oral ulcers are commonly painful lesions that are associated with numerous etiologies. Palatal ulcer could be referred as atypical oral ulcer due to unusual site predilection. The correct differential diagnosis is necessary to establish the appropriate treatment, with regards to all possible causes. Purposes: This report was intended to explain Oral Squamous Cell Carcinoma [OSCC] which is presented as atypical palatal ulcer resembling Necrotizing Sialometaplasia [NS]. Case and management: A 65 year old male, edentulous with history of uncontrolled type 2 Diabetes mellitus and experienced a gradually enlarging palatal ulcer. According to the patient, a fish bone pricked his hard palate just before the complaint. There was no lymphadenopathy, and intraoral examination revealed a solitary shallow ulcer on the right side of hard palate, covered by white pseudomembranous layer without erythematous halo. The margin of the ulcer was distinctive without induration. A month later, the lesion was progressively painful and interfere the oral function. The differential diagnoses were traumatic ulcer suspected to Eosinophilic Ulcer, Necrotizing Sialometaplasia [NS], and OSCC. Treatment plans included palliative measures and medical consultation regarding the need of biopsy. The biopsy was performed two months later. At that time, the ulcers were enlarged with indurated margin and necrotic center. A biopsy confirmed the diagnosis as OSCC with moderate differentiation. For proper treatment, the patient was referred to Oncology Department, Sardjito General Hospital. Conclusion: An atypical persistent solitary oral ulcer, especially in elderly, should prompt urgent investigation, since an oral malignancy must be foremost on the differential diagnoses list. This case report showed a progressively development of OSCC, even without preceding premalignant lesion. It is the dentists responsibility to identify any suspicion of oral premalignancy, so that proper referral can be performed earlier for reducing the mortality.
The Effect of Anacardium Occidentale Leaves Extract with Various Concentrations Used as Denture Cleanser on Streptococcus Mutans Growth Kristiana, Dewi
The Indonesian Journal of Dental Research Proceeding Book
Publisher : The Indonesian Journal of Dental Research

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Abstract

Introduction: Microbial adhesion on dentures surface can cause proliferation on bacteria colony, leads to formation of plaque which induce bad smell in mouth and denture stomatitis. There is evidence about denture stomatitis caused by another biofilm species, Streptococcus mutans (S. mutans). This study was aimed to observe efficacy differences on S. mutans growth inhibition of Anacardium occidentale leaves extract between various concentrations of 25%, 50%, and 75% as denture cleanser after 45 min immersing. Materials and methods: Samples were made from heat-cured resin acrylic plates with dimension of 10 x 10 x 1 mm. Heat-cured resin acrylic plates were immersed in Anacardium occidentale leaves extract with concentration of 25%, 50%, and 75% for 45 minutes. Each concentration contained of 8 samples. In control group, heat-cured resin acrylic plates were immersed in distilled water. To observe inhibiting effect of Anacardium occidentale leaves extract on S. mutans growth,spectrophotometer was used. Data were analyzed using one way ANOVA and LSD test. Results: Data analyses using one way ANOVA showed significant differences (p<0.05). In LSD test, significant differences on S. mutans growth inhibition effect of Anacardium occidentale leaves extract between concentration 25%, 50%, and 75% after immersing heat-cured resin acrylic plates for 45 minutes was found. Conclusion: In conclusion, Anacardium occidentale leaves extract in concentration of 75% used to immerse the acrylic plate for 45 minutes effectively inhibited the growth of S. mutans.
The Orthodontict Treatment Effect of Lower Incisors Proclination on Gingival Recession (A Literature Riew) Karunia, Dyah
The Indonesian Journal of Dental Research Proceeding Book
Publisher : The Indonesian Journal of Dental Research

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Abstract

The aim of orthodontic treatment is to obtain healthy, stable, and aesthetically sufficient occlusion. To achieve these objectives, malposititon teeth should be moved mesio-distally, labio-lingually, or proposed retroclination-proclination to an ideal position. Lower Incisor proclination is labially teeth movement to obtain normally dental arch, good of relation with upper teeth, and aesthetic. Orthodontic treatment effect of lower incisors proclination on gingival recession is still controversial. This paper is aimed to discuss the effects of lower incisors proclination on gingival recession. Condition of periodontal tissues is influenced by number of factors, namely individual variations in tissue morphology and their responses, applied pressure type, poor oral hygiene, age, minimal attached gingival, tooth malposition, fenestration, poor oral hygiene, alveolar bone defects, as well as mechanical trauma such as orthodontic treatment. Gingival recession has close relationship with anatomy structure, such alveolar bone thickness and height, gingival thickness and texture, as well as tooth position. Study on 11-15 years old subjects, grouped into 3, and treated with fixed appliance, removable appliance, and activator showed different depth increases in gingival sulcus during the treatment. The worst inflammation symptoms occurred in patients treated with fixed appliances. Boyd studies on periodontal status of adults, youths, and juveniles using fixed appliance showed no significant gingival recession. Condition of thin and delicate texture gingival as well as thin alveolar plate bone support is more sensitive to gingival recession than thick and fibrous gingival, supported by thick alveolar bone. When teeth which supported by very thin alveolar plate is moved labially (proclined) from jaw, gingival recession would occur. Thin supporting bone can cause release of attached gingival, resulting in recession. Tooth with adequate/normal attached gingival can undergo local recession during orthodontic treatment. It relates with excessive orthodontic force application, which impedes recovery or remodel of the alveolar bone. Based on reported results by various authors, it can be concluded that lower incisors proclination does not always cause gingival recession. It depends on several predisposition factors, including anatomy of very thin cortical alveolar bone plate, narrow attached gingival/keratin, inadequate/thin gingival structure, labially positioned lower Incisors, excessive orthodontic forces for proclination movement, far distance of proclination movement, poor oral hygiene, and age. These factors must be considered in developing treatment planning in order to avoid unnecessary risks and achieve optimal and satisfying treatment objectives.
Effect of Copper (II) Chloride Concentration towards Copper Ions Sorption on Natural Zeolite from Wonosari Irnawati, Dyah; Widjijono, Widjijono; Wijaya, Karna; Asmara, Widya
The Indonesian Journal of Dental Research Proceeding Book
Publisher : The Indonesian Journal of Dental Research

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Abstract

Copper-containing zeolite has been developed as an antibacterial material. It is obtained by reacting zeolite and salt solution with varied concentration of copper. Natural zeolite is abundant in Wonosari, Yogyakarta. The aim of this research was to investigate the concentration effect of copper (II) chloride solutions towards copper ions sorption on natural zeolite from Wonosari. Copper (II) chloride dihydrate powders, CuCl2. 2H2O, (Merck, Germany) and natural zeolite (Wonosari, Indonesia) were used. Zeolite powder (100 mesh) was washed and dried (200oC/2 hours). Copper (II) chloride solution with different concentrations (0.05 M, 0.10 M, 0.15 M, 0.20 M, and 0.25 M) were prepared. Zeolite and CuCl2 solutions (50 g/250 ml) were reacted at 60oC for 1 hour (n=5). The solutions were filtered, washed, and dried (100oC/24 hours). Copper ions amount were measured by XRF (Canberra Inc., USA). The data were analyzed by one way Anova. Mean values (% weight) of copper ions amount were 0.441 ± 0.029 % (0.05 M group), 0.588 ± 0.027 % (0.10 M group), 0.657 ± 0.014 % (0.15 M group), 0.676 ± 0.037 % (0.20 M group), and 0.737 ± 0.039 % (0.25 M group). The Anova showed that CuCl2 concentration influenced copper ions amount significantly (p<0.01). The differences among the groups were significant, except between 0.15 M and 0.20 M groups (p>0.05). Copper (II) chloride concentration influenced the copper ions sorption on natural zeolite from Wonosari. The 0.25M CuCl2 solution gave the highest copper ions amount.
Relationship Between Dental Arch and Vertical Facial Morphology on Deutero-Malays Population Christnawati, Christnawati; Karunia, Dyah
The Indonesian Journal of Dental Research Proceeding Book
Publisher : The Indonesian Journal of Dental Research

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Abstract

Introduction: Vertical facial morphology characterized by steepness on mandibular plane (MP-SN) is an important variable in determining orthodontic diagnosis and treatment plan. Subjects with steepest mandibular plane angle tend to have larger teeth and narrower dental arch. The purpose of this study was to determine the relationship between dental arch and vertical facial morphology on Deutero-Malays population. Materials and Methods: Lateral cephalograms were obtained from 50 subjects. Inclusion criteria of subjects were including: 1) at least two original generation of Deutero-Malays; 2) never or not under orthodontic and orthognathic treatment; 3) having Class I Angle first molar relationship; 4) having full dentition except third molars; 5) showing regular or mild degree of irregularity according to Mal-alignment Index (Mal I); 6) no cups or interproximal caries; 7) overjet 2-4 mm; and 8) overbite 1/3 incisally lower incisor teeth. Vertical facial morphology was measured by determining steepness of mandibular plane (MP-SN) on lateral cephalogram using DBSWIN program. The measurement of dental arch perimeter length and width was conducted. Collected data was tabulated and analysed using correlation test. Result: The results of this study showed no significant correlation between steepness of mandibular plane and dental arch perimeter length and width on upper and lower arch. Conclusion: In conclusion, there was no relationship between vertical facial morphology and dental arch perimeter length as well as dental arch width on upper and lower arch.
Cantilever Bridge Design as Esthetic Restoration on Post Endodontic Treatment: Case Report Fatmawati, Dwi Warna Aju
The Indonesian Journal of Dental Research Proceeding Book
Publisher : The Indonesian Journal of Dental Research

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Abstract

In dentistry, aesthetic and cosmetic had become patient demands, because it was related with beauty. In aesthetic restorative and cosmetic treatment, dentists were not only concerned in beauty but also must consider function of restoration. Thus, dentists must select materials and designs that had ability on occlusion and mastication bearing for long time in oral cavity. Dentures or restoration treatment that had similar color with tooth was known for a long time, because it can improve aesthetic and self-confidence. The aim of this case report was to explore aesthetic restoration used in cantilever bridge on post endodontic treatment subject. This bridge can be used as a more simple alternative treatment for subject whose restorative was broken and used partial denture. 
Anti-Inflammatory Activity of Ethanol Extract of Cashew Stem Bark (Annacardium Occidentale L.) on Rat Paw Edema Induced by Carrageenan Harsini, Harsini; Sutardja, Iwa; Martono, Sudibyo; Sunarintyas, Siti; Sudarsono, Sudarsono
The Indonesian Journal of Dental Research Proceeding Book
Publisher : The Indonesian Journal of Dental Research

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Abstract

Introduction: Cashew stem bark (Anacardium occidentale L.) was traditionally used to cure inflammation in the oral cavity. Phenolic substances such as phenol and anacardic acid that have anti-inflammatory effect was found in cashew stem bark. The aim of this study was to investigate the anti-inflammatory activity of the ethanol extract of cashew stem bark and indometazine as Non-steroid anti-inflammatory drug. Materials and Methods: Cashew stem bark was collected from Faculty of Dentistry, Universitas Gadjah Mada, Yogyakarta, Indonesia. Extraction was done by maceration method using ethanol as solvent. Anti-inflammatory activity of 40 mg/kg bw, 80mg/kg bw, 160mg/kg bw dosage of cashew stem bark extract was monitored and indometazine 10 mg/kg bw was used as positive control. Edema volume determination on rat paw was counted as area under cure (AUC) value and anti-inflammatory percentage. Result: This study result showed that total phenolic content on cashew stem bark was 12.25 ± 0.26% w/w gallic acid equivalent (GAE). The anti-inflammatory activity of cashew stem bark extract in this study were 9.985±6.483% for 40mg/kg BW, 15.576±6.754% for 80mg/kg bw, 25.87±19.7% for 160mg/kg bw and 56.85 ±15.52% for Indometazine 10 mg/kg bw. Analysis of Variance (ANOVA) method was applied on the results and showed significant anti-inflammatory activity of ethanol extract on cashew stem bark (p<0.05). Conclusion: In conclusion, ethanol extract of cashew stem bark has anti-inflammatory activity. However, its’ activity is lower than indometazine.

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