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Global Medical and Health Communication

gmhc
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Published by Universitas Islam Bandung

ISSN : 23019123 EISSN : 24605441 DOI : https://doi.org/10.29313/gmhc

Core Subject : Health, Science,

Dentistry Health Professions Immunology & microbiology Nursing Public Health

Global Medical and Health Communication is a journal that publishes research articles on medical and health published every 4 (four) months (April, August, and December). Articles are original research that needs to be disseminated and written in English. Subjects suitable for publication include but are not limited to the following fields of anesthesiology and intensive care, biochemistry, biomolecular, cardiovascular, child health, dentistry, dermatology and venerology, endocrinology, environmental health, epidemiology, geriatric, hematology, histology, histopathology, immunology, internal medicine, nursing sciences, midwifery, nutrition, nutrition and metabolism, obstetrics and gynecology, occupational health, oncology, ophthalmology, oral biology, orthopedics and traumatology, otorhinolaryngology, pharmacology, pharmacy, preventive medicine, public health, pulmonology, radiology, and reproductive health.

Arjuna Subject : Kedokteran - Epidemilogi

Articles 10 Documents

Search results for , issue "Vol 4, No 1 (2016)" : 10 Documents clear

Askariasis di Daerah Endemis Rendah Askariasis Tidak Meningkatkan Kejadian Tuberkulosis Aktif Ratna Dewi Indi Astuti; Herry S. Sastramihardja; Sadeli Masria
Global Medical & Health Communication (GMHC) Vol 4, No 1 (2016)
Publisher : Universitas Islam Bandung

Askariasis di daerah endemis seperti Indonesia menyebabkan polarisasi respons Th2 yang dapat menekan respons Th1 yang penting dalam perlawanan terhadap tuberkulosis melalui penekanan ekspresi IL-12Rẞ2 oleh IL-4. Tujuan penelitian ini adalah mencari hubungan antara kejadian askariasis dan tuberkulosis aktif di daerah endemis rendah askariasis. Penelitian observasional analitik dilakukan pada 30 penderita dewasa tuberkulosis paru aktif baru dan 29 penderita tuberkulosis laten. Penelitian dilaksanakan di Kota Bandung selama periode April–Juni 2014. Pemeriksaan telur Ascaris lumbricoides dilakukan dengan teknik Kato-Katz smear dan pengukuran kadar reseptor terlarut IL-12Rẞ2 dalam plasma mengunakan metode enzyme linked immunosorbent assay (ELISA). Hasil penelitian menunjukkan proporsi askariasis pada penderita tuberkulosis aktif secara signifikan lebih rendah (5 dari 30 subjek) dari proporsi askariasis pada penderita tuberkulosis laten (13 dari 29 subjek) dengan p=0,019. Penghitungan jumlah telur menunjukkan semua subjek askariasis menderita askariasis intensitas ringan. Kadar reseptor terlarut IL-12Rẞ2 pada penderita tuberkulosis aktif dan laten dengan askariasis maupun tanpa askariasis tidak berbeda signifikan. Simpulan penelitian ini adalah askariasis intensitas ringan tidak menekan respons Th1 dan tidak meningkatkan kejadian tuberkulosis aktif di daerah endemis rendah askariasis. ASCARIASIS IN LOW ENDEMIC AREA DOES NOT ASSOCIATE WITH THE INCREASE INCIDENCE OF ACTIVE TUBERCULOSISPolarization toward Th2 response in ascaris investation suppresses Th1 responses which is important in defence against tuberculosis. Such suppression is hipothesized to supress the expression of IL-12Rẞ2 by IL-4. The purpose of this study was to find out the relationship between ascaris investation and TB in low endemic area of ascariasis that is endemic for TB. We gathered samples from 30 adult active pulmonary TB patients and 29 adult latent TB patients as control. The study was performed in Bandung during April to June 2014. Ascaris investation was established with Kato-Katz smear technique and the detection of plasma level of the soluble receptor of IL-12Rẞ2 was conducted with enzyme linked immunosorbent assay (ELISA). We showed that the proportion of ascaris investation significantly higher in latent TB patients (13 from 29 subjects) compared to in active Tb patients (5 from 30 subjects) with p value 0.019. All subjects positive for ascaris investation had low intensity of investation in accordance with low endemicity. Also, the median level of IL-12Rẞ2 did not differ between active and latent TB patients with ascaris or without ascaris investation. We concluded that low intensity of ascaris investation does not associate with suppression of Th1 response, as assessed by IL-12Rẞ2 receptor level, hence does not associate with the increase incidence of active tuberculosis.

Otitis Media Supuratif Kronik pada Anak Muhamad Faris Pasyah; Wijana Wijana
Global Medical & Health Communication (GMHC) Vol 4, No 1 (2016)
Publisher : Universitas Islam Bandung

Otitis media supuratif kronik (OMSK) merupakan masalah pada anak dan remaja yang berdampak pada fisik, sosial serta psikologis dan mempunyai prevalensi yang tinggi. Kondisi ini merupakan proses peradangan akibat infeksi mukoperiosteum rongga telinga tengah yang ditandai oleh perforasi membran timpani dan keluar sekret yang terus menerus atau hilang timbul selama 3 bulan, serta dapat menyebabkan perubahan patologik yang permanen. Tujuan penelitian mengetahui gambaran OMSK pada anak. Penelitian dilakukan secara deskriptif retrospektif di poliklinik Otologi Departemen Ilmu Kesehatan Telinga Hidung Tenggorokan-Kepala Leher (THT-KL) RSUP Dr. Hasan Sadikin Bandung periode Januari 2012–Desember 2013. Diagnosis ditegakkan berdasarkan anamnesis dan pemeriksaan fisis. Didapatkan pasien OMSK anak laki-laki 53% dan pasien anak perempuan 47%. Jumlah OMSK tipe benigna 83% dan tipe maligna 17%. Komplikasi terbanyak OMSK pada anak adalah mastoiditis 32%. Angka putus berobat pada pasien anak dengan OMSK sebesar 60%. Simpulan, penderita OMSK pada anak lebih banyak pada laki-laki tipe benigna dan angka pasien putus berobat masih banyak ditemukan. CHRONIC SUPPURATIVE OTITIS MEDIA IN CHILDRENChronic supurative otitis media (CSOM) is a common problem among children and adolescent that give physical, social, and psycological effect, and its prevalence was quite a lot. It is a process of inflammation due to infection of middle ear mucoperiosteum which cause the perforation of timpanic membran, the drainage of ear for at least three months duration, that also could cause middle ear permanent pathological changes. The aim of the study was to provide characteristic of CSOM in pediatric patients. This study was retrospective descriptive study that was conducted at Otology Clinic of Otorhinolaryngology-Head and Neck Surgery (ORL-HNS) Departement Dr. Hasan Sadikin General Hospital. This study was a retrospective descriptive study that was conducted during the period of January 2012–December 2013. Diagnoses were made from anamnesis and physical examination. There were boys 53% and girls 47% that had CSOM. Eighty three patients were having benign CSOM, then others 17% were having malignant one. It was also known that the most complication was mastoiditis 32%. The drop out number of patients was 60%. In conclusions, there are more boys than girls that have CSOM and benign CSOM are more frequent than malignant ones. The insidence of drop out is quite many.

Prevalensi Servisitis Gonore pada Wanita Hamil di Rumah Sakit Khusus Ibu dan Anak Kota Bandung Tahun 2015 Armina Haramaini; Rachmatdinata Rachmatdinata; Rasmia Rowawi
Global Medical & Health Communication (GMHC) Vol 4, No 1 (2016)
Publisher : Universitas Islam Bandung

Gonore adalah infeksi menular seksual (IMS) yang disebabkan oleh Neisseria gonorrhoeae (N. gonorrhoeae). Salah satu manifestasi klinis gonore pada wanita adalah servisitis yang sebagian besar asimtomatik dan bila tidak diterapi servisitis gonore pada wanita hamil dapat menimbulkan komplikasi pada ibu, kehamilan, dan janin. Tujuan penelitian ini mengetahui prevalensi servisitis gonore pada wanita hamil di Rumah Sakit Khusus Ibu dan Anak (RSKIA) Kota Bandung tahun 2015. Penelitian ini merupakan penelitian deskriptif dengan desain potong lintang. Subjek penelitian adalah 100 wanita hamil dengan bahan pemeriksaan adalah apus endoserviks. Diagnosis servisitis gonore ditegakkan jika pada sedian apus gram ditemukan jumlah polimorfonuklear (PMN) >30/lapang pandang besar (lpb) dan diplokokus gram negatif intraseluler, serta hasil PCR N. gonorrhoeae positif. Hasil PCR N. gonorrhoeae pada seluruh subjek penelitian negatif. Namun, 41 orang (41%) subjek penelitian ditemukan jumlah PMN >30/lpb, tanpa diplokokus gram negatif intraseluler, dan didiagnosis servisitis nongonore. Simpulan penelitian ini, yaitu prevalensi servisitis gonore pada wanita hamil di RSKIA Kota Bandung tahun 2015 adalah 0%. Hasil tersebut diduga karena karakteristik sebagian besar subjek penelitian tidak termasuk ke dalam risiko tinggi mengidap IMS. PREVALENCE OF GONORRHEA CERVICITIS IN PREGNANT WOMEN IN SPECIAL HOPISTAL MATERNAL AND CHILD BANDUNG YEAR 2015Gonnorhea is a sexually transmitted infection (STI) that is caused by Neisseria gonorrhoeae. One of the clinical manifestation of gonnorhea in female is cervicitis, that mostly asymptomatic. If it is left untreated, gonnorheal cervicitis in pregnant woman will cause complication to the mother, pregnancy, and fetus. The aim of this study was to know the prevalence of gonnorheal cervicitis in pregnant woman in mother and children hospital (RSKIA) Bandung in year 2015. The study design was cross sectional and descriptive. Subjects were 100 pregnant women, which was taken the sample from endocervical swab. Diagnosis of gonnorheal cervicitis was established if more than 30/high power field (hpf) polymorphonuclear (PMN) and extra or intracellular gram negative diplococcus found from gram staining, also positive PCR result for N. gonorrhoeae. The result of PCR in all subjects were negative. But, there were 41 subjects with PMN more than 30/hpf, with no intra or extra cellular diplococcus found, and those subjects were diagnosed as non gonnorheal cervicitis. Conclusion of this study was that the prevalence of gonorrheal cervicitis of pregnant woman in RSKIA Bandung in year 2015 is 0%. This result was suggested due to the subjects characteristics in this study mostly were not high risk for STI.

Penggunaan Pemutih Gigi Mengandung Hidrogen Peroksida 40% Dibanding dengan Strawberry (Fragaria X ananassa) terhadap Ketebalan Email, Kadar Kalsium, dan Kekuatan Tekan Gigi Yuniarti Yuniarti; Achadiyani Achadiyani; Nani Murniati
Global Medical & Health Communication (GMHC) Vol 4, No 1 (2016)
Publisher : Universitas Islam Bandung

Estetik gigi adalah hal yang penting bagi seseorang. Salah satu hal yang memengaruhi estetik gigi adalah warna gigi. Perubahan warna gigi dapat diperbaiki dengan pemutihan gigi hidrogen peroksida 40% dan strawberry (Fragaria x ananassa). Penelitian eksperimental laboratoris membandingkan gigi kelompok kontrol dengan dua kelompok perlakuan gigi yang diolesi bahan pemutih gigi hidrogen peroksida 40% atau direndam dalam strawberry. Penelitian dilakukan di Laboratorium Histologi Fakultas Kedokteran dan Laboratorium Kimia Universitas Padjadjaran, serta Laboratorium ITMKG Fakultas Kedokteran Gigi Universitas Padjadjaran periode Agustus 2012–Mei 2013. Kelompok masing-masing memakai sembilan buah gigi premolar permanen yang diukur ketebalan email secara mikroskopis, kadar kalsium memakai spektrofotometer, dan kekuatan tekan memakai universal testing machine. Uji statistik pengukuran ketebalan email adalah uji-t, pengukuran kadar kalsium memakai Wilcoxon dan Mann Whitney, sedangkan hasil pengukuran kekuatan gigi diuji dengan Kruskal Wallis dan Post Hoc Mann Whitney. Hasil uji penurunan ketebalan email kedua kelompok perlakuan dibandingkan dengan kontrol (uji dependent t, p=0,002 dan p=0,0001) dan perbedaan penurunan ketebalan email antara kedua kelompok (uji independent p=0,0375) adalah signifikan. Penurunan kadar kalsium kedua kelompok dibandingkan dengan kontrol (uji Wilcoxon p=0,173 dan p=0,441) dan perbedaan kadar kalsium antara kedua kelompok tersebut (uji Mann Whitney p=0,480) tidak signifikan. Uji kekuatan tekan gigi signifikan antara kontrol dan dua kelompok perlakuan (uji Kruskall Wallis p=0,014), namun bila memakai uji Post Hoc Mann Whitney hanya penurunan kekuatan tekan gigi antara kontrol dan hidrogen peroksida yang berbeda signifikan (p=0,02). Simpulan, hidrogen peroksida 40% menurunkan ketebalan email dan kekuatan tekan gigi lebih besar dibanding dengan strawberry, tetapi tidak menurunkan kadar kalsium lebih besar dibanding dengan strawberry. TEETH BLEACHING HYDROGEN PEROXIDE 40% COMPARED WITH STRAWBERRY (FRAGARIA X ANANASSA) TO ENAMEL THICKNESS, CALCIUM LEVEL AND COMPRESSIVE STRENGTH OF TEETHTeeth esthetics is important for someone. One thing influence teeth estheticsis is colour. Dental bleaching using hydrogen peroxide 40% and strawberry (Fragaria x ananassa) is conservative alternative to restore the esthetics of either stained teeth. This study was an experimental laboratory by comparing control group with two treatment groups were teeth smeared hydrogen peroxide 40% or soaked in strawberry. This study was done in Histology Laboratory Faculty of Medicine and Chemical Laboratory Universitas Padjadjaran, and ITMKG Laboratory Faculty of Dentistry Universitas Padjadjaran period August 2012–May 2013. Each group used nine permanent premolars, which will be measured email thickness microscopically, calcium levels using spectrophotometer, and compressive stregth using universal testing machine. The statistical test used for thickness measurement results email was the t-test, for measurement of calcium levels using Wilcoxon test and Mann Whitney while for tooth strength measurements were tested using Kruskal Wallis and Post Hoc Mann Whitney. The results obtained for the test email thickness reduction of both treatment groups compared with the control (test dependent t, p=0.002 and p=0.0001) and a decrease in the thickness difference between the two treatment groups email (independent test, p=0.0375) were significant. The results of the impairment test calcium levels both treatment groups compared with controls (Wilcoxon p=0.173 and p=0.441), and the difference in calcium levels between the two groups (Mann Whitney test, p=0480) was not significant. The results of compressive strength test teeth showed significant gains between the control group and two treatment groups (Kruskall Wallis test, p=0.014), However when using Post Hoc Mann Whitney test only decrease the compressive strength of the teeth between the control group and the treatment group were significant hydrogen peroxide (p=0.02). In conclusions, 40% hydrogen peroxide causes a decrease in the thickness of the email and the compressive strength is greater than strawberry but do not cause a decrease in blood calcium level greater than strawberry.

Determinan Peresepan Polifarmasi pada Resep Rawat Jalan di Rumah Sakit Rujukan Yuke Andriane; Herry S. Sastramihardja; R. Ruslami
Global Medical & Health Communication (GMHC) Vol 4, No 1 (2016)
Publisher : Universitas Islam Bandung

Resep polifarmasi (≥5 jenis obat/resep) berpotensi meningkatkan interaksi obat, efek samping obat, dan masalah lain. Pasien yang berobat ke rumah sakit (RS) rujukan umumnya berpenyakit kronik, dengan komorbiditas dan komedikasi. Dilakukan penelitian potong silang untuk menganalisis determinan peresepan polifarmasi dari berbagai klinik rawat jalan di RS rujukan di Bandung. Analisis statistik menggunakan uji chi square dan dihitung rasio prevalensi (RP). Selama bulan Oktober 2012 terdapat 2.548 resep dari lima klinik rawat jalan dengan jumlah resep polifarmasi terbanyak. Prevalensi polifarmasi adalah 32% dan median jumlah jenis obat adalah 5 (rentang: 5–11). Terdapat perbedaan karakteristik pasien dalam hal usia ≥60 tahun (59,8% vs 44,8%; p<0,001), jenis kelamin laki-laki (57,1% vs 44,6%; p<0,001), peserta Askes (73,6% vs 56,1%; p<0,001), dan asal poliklinik: kardiovaskular (72,1% vs 33,1%; p<0,001) antara yang menerima resep polifarmasi dan tidak polifarmasi. Faktor dominan terhadap peresepan polifarmasi adalah dari klinik kardiovaskular (RP:8,80; IK95%: 6,35–12,19). Faktor lain dengan risiko polifarmasi >3 kali adalah dari klinik geriatri (RP:6,68; IK95%: 4,43–10,08) dan peserta Askes (RP:6,23; IK95%: 3,49–11,12). Prevalensi polifarmasi resep gabungan beberapa klinik (574 pasien) lebih besar, yaitu 59,8%. Simpulan, prevalensi peresepan polifarmasi di RS rujukan cukup tinggi, terlebih jika pasien menerima resep dari berbagai klinik. Determinan utama peresepan polifarmasi di RS rujukan adalah dari poli kardiovaskular, poli geriatri, dan peserta Askes.DETERMINANTS FOR POLYPHARMACY PRESCRIBING OF THE PRESCRIPTION IN THE OUTPATIENT CLINICS OF REFERRAL HOSPITALPolypharmacy prescription (≥5 drugs in one prescription) potentially increased drug-drug interaction, side effects, and other problems. Patients who come to referral hospital usually were with chronic diseases, comorbidities and comedications. A cross sectional study was performed to analyze the determinants for polypharmacy prescription from clinics in referral hospital in Bandung. Data were analyzed using chi-square test and prevalence ratio (PR) were calculated. During October 2012, there were 2,548 prescriptions from five clinics with highest number of prescription. Prevalence of polypharmacy prescription was 32%, the median number of drugs written were 5 (ranged: 5–11). The characteristics of the patients showed a difference in aged ≥60 years (59.8% vs 44.8%, p<0.001), gender: males (57.1% vs 44.6%, p<0.001), had health insurrance (73.6% vs 56.1%, p<0.001), and origin cardiovascular clinic (72.1% vs 33.1%, p<0.001) between those receiving polypharmacy prescriptions and those receiving non polypharmacy prescription. The dominant factor for polypharmacy prescription was treated at cardiovascular clinic (PR:8.80, 95%CI: 6.35–12.19), followed by treated at geriatry clinic (RP:6.68, 95%CI: 4.43–10.08) and had health insurrance (RP:6.23, 95%CI: 3.49–11.12). Polypharmacy of combined prescriptions (574 patients) was 59.8%. In conclusions, prevalence of polypharmacy prescription in referral hospital in Bandung is high, even higher in patients received combined prescriptions. Main determinants for polypharmacy prescription in referral hospitals are being treated at cardiovascular clinic, geriatry clinic, and having health insurance.

Deteksi Dini Penyakit Parkinson: Pengetahuan, Sikap, dan Perilaku Petani Desa Tanjung Wangi Cicalengka Mengenai Bahaya Pestisida bagi Kesehatan Arief Budi Yulianti; Siska Nia Irasanti; Meta Maulida; Mia Kusmiati; Adhika Putra Rahmatullah
Global Medical & Health Communication (GMHC) Vol 4, No 1 (2016)
Publisher : Universitas Islam Bandung

Pestisida bersifat toksik bagi manusia dan lingkungan sekitarnya. Petani adalah kelompok masyarakat berisiko tinggi terpapar pestisida. Tingkat pengetahuan, sikap, dan perilaku petani mengenai bahaya pestisida sangat diperlukan agar keputusan untuk menggunakan pestisida sesuai dengan jenis, waktu, dan cara menjadi tepat. Penelitian ini dilaksanakan selama bulan Maret–Juli 2015 dan merupakan penelitian observasional dengan subjek penelitian petani Desa Tanjung Wangi. Subjek penelitian diambil secara acak diperoleh 62 subjek penelitian yang terdiri atas 47 laki-laki dan 15 perempuan. Tingkat pengetahuan, sikap, dan perilaku diukur dengan kuesioner yang sudah divalidasi. Pengukuran gejala dini Parkinson menggunakan kuesioner PDQ39 yang sudah dimodifikasi. Diperoleh tingkat pengetahun dan sikap petani mengenai bahaya pestisida skor terendah 0,70 dan tertinggi 0,97 dengan nilai median 0,80 dan modus 0,79. Perilaku pestisida ini mengenai tata cara penggunaan pestisida skor terendah 0,64, tertinggi 1 dengan modus 0,84. Gejala dini Parkinson pada petani di Desa Tanjung Wangi skor tertendah 0,74 dan tertinggi 1 dengan nilai median 0,84 dan modus 0,91. Simpulan, pengetahuan, sikap, dan perilaku petani Desa Tanjung Wangi mengenai bahaya pestisida baik. Hasil yang diperoleh dari kuesioner tidak menggambarkan kondisi petani di lapangan. Hal ini dapat terjadi karena peneliti tidak memasukkan unsur ekonomi sebagai salah satu faktor penentu pengambilan keputusan menggunakan pestisida sehingga diperlukan upaya edukasi petani. DETECTION-EARLY OF PARKINSON'S DISEASE: KNOWLEDGE, ATTITUDES, AND BEHAVIOR FARMER IN DESA TANJUNG WANGI ABOUT PESTICIDES TOXICITIES TOWARD HEALTHPesticides are toxic for human and environment. Farmers are people at high risk of exposure to pesticides. The level of knowledge, attitudes, and behaviors of farmers about pesticides toxicity needed, so the decision to use pesticides be expected right. This research held on March–July 2015, observational method with subjects farmers in Desa Tanjung Wangi were taken randomly. Number of samples were 62 person consisted of 47 men and 15 women. The level of knowledge, attitudes, behaviors and detectionearly of Parkinson’s disease were measured with a questionnaire PDQ39 modified. The lowest score of level knowledge and attitudes about pesticides toxicities was 0.70 and the highest was 0.97 with median and modus 0.80 and 0.79, respectively. The lowest score of behavior regarding the method of pesticides used was 0.64 and the highest was 1 with modus 0.84. The lowest score of detection-early of Parkinson’s disease was 0.74 and the highest was 1 with median and modus 0.84 and 0.91, respectively. In conclusions, farmers knowledge, attitudes and behavior regarding pesticides toxicities are good. But the questionnaire wasn’t describe the really condition in field, especially in economic issues that affecting decisions about pesticides to be used, so educating to understand about pesticides toxicities needs to be done.

Perbandingan Pengetahuan dengan Sikap dalam Pencegahan Demam Berdarah Dengue di Daerah Urban dan Rural Titik Respati; Budiman Budiman; Eka Nurhayati; Fajar A. Yulianto; Yudi Feriandi
Global Medical & Health Communication (GMHC) Vol 4, No 1 (2016)
Publisher : Universitas Islam Bandung

Demam berdarah dengue tidak saja menimbulkan beban penyakit, akan tetapi juga beban ekonomi yang tinggi bagi individu, keluarga maupun negara. Belum terdapat obat atau vaksin yang efektif telah membatasi pilihan dalam melakukan pencegahan dan pengobatan. Program yang dilaksanakan adalah vektor kontrol untuk membatasi transmisi virus yang memerlukan peran serta masyarakat secara terus menerus. Penelitian ini bertujuan mengetahui perbedaan persepsi tentang penyakit dengan praktik dalam pencegahan demam berdarah di daerah urban (Tamansari) dan daerah rural (Ciparay). Penelitian dilakukan pada total 208 responden di Tamansari Bandung dan 122 responden di Ciparay pada bulan Februari sampai Maret 2015. Hasil penelitian menunjukkan bahwa kondisi lingkungan di kedua daerah belum baik dengan sanitasi dasar terutama sistem pembuangan air limbah yang belum memadai. Perbedaan tampak dalam hubungan antara persepsi mengenai demam berdarah dan sikap dalam praktik pencegahan. Di Tamansari persepsi mengenai demam berdarah dengue berhubungan dengan sikap dalam memberantas sarang nyamuk (OR 14,297; p<0,05). Ciparay menunjukkan fenomena yang berlawanan, persepsi mengenai demam berdarah dengue tidak berhubungan dengan sikap dalam pemberantasan sarang nyamuk (OR 0,327; p>0,05). Simpulan, terdapat perbedaan persepsi dengan praktik pencegahan demam berdarah dengue antara responden Tamansari dan Ciparay. COMPARISON ON KNOWLEDGE, ATTITUDE AND PRACTICE REGARDING DENGUE PREVENTION IN URBAN AND RURAL AREADengue fever is not only become a burden of disease but can also become burden on economy affected individual person, family and country. At present there weren’t any specific drug and no effective vaccine yet, that the prevention was limited to disease prevention through disease management and vector control which needed continuing community participation. This study aims to understand the difference between perception and the practice in vector control activities between urban and rural areas. Data was collected using questionnaires from 208 and 122 respondents from Tamansari dan Ciparay respectively since February to March 2015. Results showed that the environment condition in both study area were not good especially for the basic sanitation facilities. There were differences between perception of the disease and the practice of vector control in these two areas. Perception of the disease associate with practice in vector control in Tamansari was OR 14.297, p<0.05 while it was the other way in Ciparay was OR 0.327, p>0.05. In conclusion there are differences between Tamansari and Ciparay regarding perception of dengue fever with the practice on vector control.

Hubungan Faktor Risiko dan Karakteristik Gejala Klinis dengan Kejadian Pneumonia pada Balita Lisa Adhia Garina; Sherly Fajariani Putri; Yuniarti Yuniarti
Global Medical & Health Communication (GMHC) Vol 4, No 1 (2016)
Publisher : Universitas Islam Bandung

Pneumonia masih merupakan penyebab kesakitan dan kematian pada balita di negara berkembang. Faktor risiko pneumonia yang selalu ada (definite risk factor) meliputi gizi kurang, bayi berat lahir rendah (BBLR), tidak memberikan ASI, polusi udara di dalam ruang, dan pemukiman padat. Gejala pneumonia bervariasi bergantung pada usia penderita dan penyebab infeksinya. Tujuan penelitian ini menilai hubungan faktor risiko dan karakteristik gejala klinis dengan kejadian pneumonia pada balita. Penelitian cross sectional dilaksanakan di UPT Puskesmas Ibrahim Aji Kota Bandung periode April–Juni 2012 pada anak balita usia 6 bulan sampai dengan 59 bulan dengan diagnosis pneumonia dan bukan pneumonia berdasarkan kriteria WHO. Data demografis, faktor risiko, dan karakteristik gejala klinis dicatat dalam formulir penelitian. Penderita pneumonia pada balita terbanyak berusia 6–24 bulan (72%), berjenis kelamin laki-laki (63%), status gizi kurang (56%) berdasarkan BB/U, tidak BBLR (95%), diberikan ASI eksklusif (91%), dan imunisasi dasar lengkap (93%). Analisis uji hubungan antara kejadian pneumonia dan status gizi kurang berdasarkan BB/U didapatkan hasil p<0,001; r=-0,7 dengan lama demam (p=0,024; r=-0,2), lama batuk (p=0,048; r=-0,2), dan takipnea (p<0,001; r=-0,8). Simpulan, terdapat hubungan status gizi kurang, lama demam, lama batuk, dan takipnea dengan kejadian pneumonia pada balita.CORRELATION OF RISK FACTORS AND CLINICAL CHARACTERISTICS WITH THE INCIDENCE OF PNEUMONIA IN CHILDREN UNDER FIVE YEARSPneumonia is the leading infectious cause of death in children mostly in developing countries. Risk factors on pneumonia include malnutrition, low birth weight, non breastfeeding, air room pollution, and densely populated area. Symptoms of pneumonia vary depending on the age of the patient and cause infection. The purpose of this study was to assess the relationship risk factor and characteristic clinical symptoms with pneumonia. Cross-sectional study in Primary Health Care Ibrahim Aji Bandung during April–June 2012 among children aged 6 months to 59 months with a diagnosis of pneumonia and not pneumonia based on WHO criteria. Data on demographic, risk factor, and characteristics clinical symptoms were recorded. Pneumonia mostly attacking age 6-24 months (72%), male (63%), malnutrition status (56%) based on the weight/age, non low birth weight (95%), exclusive breastfeeding (91%), and immunization (93%). The association between the incidence of pneumonia with poor nutritional status (p<0.001, r=-0.7), duration of fever (p=0.024, r=-0.2), duration of coughing (p=0.048, r=-0.2) and tachypnoea (p<0.001, r=-0.8). In conclusion, there is a relationship between poor nutritional status, duration of fever, duration of coughing, and tachypnoea with pneumonia.

Perbedaan Efek Infusa Bubuk Kedelai (Glycine max), Jamur Tiram (Pleurotus ostreatus), dan Campuran Keduanya terhadap Kadar Kolesterol LDL, Ekspresi Gen Reseptor LDL Hati, dan Berat Omentum Majus Mencit Model Hiperlipidemia Rizky Suganda Prawiradilaga; M. Nurhalim Shahib; Siti Nur Fatimah
Global Medical & Health Communication (GMHC) Vol 4, No 1 (2016)
Publisher : Universitas Islam Bandung

Angka kejadian dislipidemia di Indonesia semakin meningkat. Dislipidemia dan obesitas abdominal merupakan faktor risiko penyakit kardiovaskular. Diperlukan solusi yang efektif dengan bahan alami seperti kedelai dan jamur tiram. Tujuan penelitian ini melihat efektivitas infusa bubuk kedelai, jamur tiram, dan campuran keduanya terhadap kadar kolesterol LDL, ekspresi gen LDLR hati, dan berat omentum majus mencit percobaan. Penelitian eksperimental di Laboratorium Farmakologi RSUP Dr. Hasan Sadikin Bandung tahun 2010 memakai rancangan postes kelompok kontrol. Mencit jantan sebanyak 20 ekor dibagi 5 kelompok perlakuan, yaitu A) pakan standar, B) induksi kolesterol, C) infusa kedelai dengan induksi kolesterol, D) infusa jamur tiram dengan induksi kolesterol, dan E) infusa campuran dengan induksi kolesterol. Pada akhir penelitian mencit dikorbankan lalu dibedah untuk diambil darah jantung, juga sedikit bagian hati dan omentum majus. Kolesterol LDL darah kelompok E (12±5,48 mg/dL) sama dengan kelompok D (12±6,06 mg/dL), tetapi lebih rendah daripada kelompok C (15±5,35 mg/dL) dan kelompok B (13,5±5,45 mg/dL), namun tidak signifikan. Didapatkan ekspresi gen LDLR yang sedang pada kelompok A dan C, ekspresi gen LDLR yang lemah pada kelompok B, dan tidak terekspresi pada kelompok D dan E. Berat basah omentum majus kelompok E (0,40±0,07 g) lebih rendah bermakna dibanding kelompok A (0,55±0,07 g), B (0,8±0,49 g), C (1,28±0,28 g), D (0,74±0,11 g) (p<0,05). Berat kering omentum majus kelompok E (0,16±0,03 g) lebih rendah bermakna daripada kelompok B (0,27±0,25 g), C (0,39±0,06 g), dan D (0,31±0,07 g) (p=0,025). Simpulan, infusa kedelai 100 mg/hari meningkatkan kadar kolesterol LDL darah dan berat omentum majus, tetapi jamur tiram 75 mg/hari sebaliknya, menurunkan kadar kolesterol LDL darah dan berat omentum majus mencit. DIFFERENCES IN GIVING EFFECT OF SOYBEAN POWDER INFUSION (GLYCINE MAX), OYSTER MUSHROOM (PLEUROTUS OSTREATUS), AND MIXED OF BOTH ON LDL-C LEVELS, LDL-R GENE EXPRESSION, AND GREATER OMENTUM WEIGHT OF HYPERLIPIDEMIA MODEL MICEThe incidence of hypercholesterolemia in Indonesia are increase. Hyperlipidemia and abdominal obesity is a risk factor for cardiovascular disease. Needed an effective solution with natural substance like soy and oyster mushrooms. The purpose of this study was to see the effectiveness of the soybean powder infusion, oyster mushrooms, and a mixture of both on LDL cholesterol levels, liver LDLR gene expression, and the weight of the experimental mice greater omentum. This experimental study conducted in the Laboratory of Pharmacology Dr. Hasan Sadikin Hospital Bandung in 2010, using a posttest only. Twenty male mice were divided in five treatment groups, namely A) standard diet, B) induction of cholesterol, C) soybean infuse with cholesterol induction, D) oyster mushrooms infuse with induction of cholesterol, and E) mixed infuse with cholesterol induction. At the end of the study mice were dissected for blood drawn from the heart, taken little part of his liver, and the greater omentum were taken. The results of blood LDL cholesterol measurement group E (12±5.48 mg/dL) similar to group D (12±6.06 mg/dL) but lower than group C (15±5.35 mg/dL) and group B (13.5±5.45 mg/dL) but they were not significant. Medium LDLR gene expression was found in group A and group C, a weak LDLR gene expression in group B, and no expression LDLR gene in group D and group E. Measurement results of greater omentum wet weight group E (0.40±0.07 g) was lower than in group A (0.55±0.07 g), B (0.8±0.49 g), C (1,28±0.28 g), D (0.74±0.11 g), with significance level significant (p<0.05). Measurement results of greater omentum dry weight group E (0.16±0.03 g) was lower than in group B (0.27±0.25 g), C (0.39±0.06 g), D (0,31±0.07 g), and they were significant (p=0.025). In conclusion, soy infuse at 100 mg/day increase blood LDL cholesterol levels and increase the weight of greater omentum, whereas the opposite oyster mushrooms at 75mg/day lower blood LDL cholesterol levels and reduce the weight of greater omentum.

Pengaruh Ekstrak Etanol Buah Mahkota Dewa {Phaleria macrocarpa (Scheff) Boerl} per Oral terhadap Kontraktilitas Uterus Mencit Model Gravida Raden Anita Indriyanti; M. Sujatno; A. W. Soekandar
Global Medical & Health Communication (GMHC) Vol 4, No 1 (2016)
Publisher : Universitas Islam Bandung

Tanaman mahkota dewa {Phaleria macrocarpa (Scheff) Boerl} adalah tanaman yang tumbuh dan dimanfaatkan sebagai obat alternatif karena memiliki kandungan zat aktif yang dapat menyembuhkan berbagai penyakit. Penggunaan mahkota dewa ini tidak boleh dikonsumsi oleh wanita hamil karena dapat meningkatkan kontraksi uterus sehingga dapat menyebabkan abortus. Tujuan penelitian membandingkan efek pemberian ekstrak buah mahkota dewa dengan oksitosin terhadap kontraktilitas uterus. Penelitian eksperimental laboratorik dilakukan di Laboratorium Faal dan Farmakologi Klinik Fakultas Kedokteran Unpad Jatinangor Bandung periode Juli–November 2005 dengan memakai 27 ekor mencit gravida galur Swiss-Webster dalam 3 kelompok. Kelompok I sebagai kontrol negatif, kelompok II diberi suntikan oksitosin 0,045 mL/mnt (0,45 mU) intravena, dan kelompok III diberi ekstrak buah mahkota dewa kadar 6,25% sebanyak 0,5 mL per oral. Tiap-tiap kelompok diukur kontraktilitas uterusnya. Hasil perhitungan diolah dengan analisis varians (ANOVA) dilanjutkan dengan Uji Duncan. Pada kelompok mahkota dewa menggambarkan kontraksi yang bersifat ritmis dengan amplitudo kecil dan nilai frekuensi kontraksi tertinggi (119x/30 menit) dan perbedaan yang sangat signifikan versus kelompok kontrol tanpa perlakuan (16x/30 menit) dan kelompok oksitosin (23x/30menit). Kekuatan kontraksi pada pemberian ekstrak etanol buah mahkota dewa lebih rendah (1,2 cm) daripada kelompok kontrol tanpa perlakuan (1,6 cm), sedangkan kelompok yang diberi oksitosin menghasilkan kekuatan kontraksi paling kuat (2,6 cm). Simpulan, pemberian ekstrak etanol buah mahkota dewa menggambarkan kontraksi yang bersifat ritmis dengan amplitudo kecil serta menghasilkan frekuensi kontraksi tertinggi dan amplitudo terendah dibanding dengan kelompok kontrol dan kelompok oksitosin intravena. THE EFFECT OF MAHKOTA DEWA {PHALERIA MACROCARPA (SCHEFF) BOERL} FRUIT ETHANOL EXTRACTS PER ORAL TO UTERINE CONTRACTION OF GRAVIDA TYPE MICEMahkota dewa {Phaleria macrocarpa (Scheff) Boerl} known as a plant that used as an alternative medicine. Because of its rich active substances, it is believed to heal many diseases. Caution for this plant is that it must not be consumed by pregnant women, because it may increase the uterine contraction and cause an abortion. The aim of strudy was to compare the effect of Phaleria macrocarpa (Scheff) Boerl fruit extracts and oxytocin to uterine contraction. The experimental study with complete randomized had been conducted to 27 pregnant Swiss-Webster mouses in Laboratorium Faal and Farmakologi Klinik Fakultas Kedokteran Unpad Jatinangor Bandung periode July–November 2005 that devided in 3 groups. Group I served as a negative control, group II was given oxytocin 0.045 mL/mnt (0.045 mU) intravenous, and group III was given mahkota dewa ethanol extract 6.25% for 0.5 mL orally. The measurement for each group’s uterine contractility consisted of the number of frequency and level of contraction strength. The result analyzed using variant analysis (ANOVA) and Duncan test. Result showed that in mahkota dewa group, a rhythmical contraction with low amplitudo with the highest point (119x/30 mnt) for contraction frequency, compared to control group(16x/30 mnt) and oxytocin group (23x/30 mnt). It showed that in group given mahkota dewa ethanol extract the level of contraction strength was lower (1.2 cm) than control group (1.6 cm). While group given oxytocin intravenously had the highest level of contraction strength (2.6 cm). In conclusion mahkota dewa ethanol extract performed a rhythmical contraction with low amplitudo and has the highest point for contraction frequency, and the lowest level of contraction strength compared to those in control group and oxytocin group.

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Home Page

OAI Link

Editorial Team

Contact

Reviewer

Google Scholar

Contact Name Agus Chalid

Contact Email gulid.p@gmail.com

Phone +6285220013654

Journal Mail Official gmhc.unisba@gmail.com

Editorial Address Jalan Hariangbanga No. 2, Tamansari, Bandung 40116

Location Kota bandung, Jawa barat INDONESIA

Abstract

Abstract

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Abstract

Contact Name
Agus Chalid

Contact Email
gulid.p@gmail.com

Phone
+6285220013654

Journal Mail Official
gmhc.unisba@gmail.com

Editorial Address
Jalan Hariangbanga No. 2, Tamansari, Bandung 40116

Location
Kota bandung,

Jawa barat

INDONESIA