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Dian Yosi Arinawati
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dianyosi@umy.ac.id
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INDONESIA
Insisiva Dental Journal : Majalah Kedokteran Gigi Insisiva
ISSN : 22529764     EISSN : 26859165     DOI : 10.18196/idj
Core Subject : Health,
Insisiva Dental Jurnal memberikan informasi tentang ide, opini, perkembangan dan isu-isu di bidang kedokteran gigi meliputi klinis, penelitian, laporan kasus dan literature review.
Arjuna Subject : -
Articles 14 Documents
Search results for , issue " Vol 1, No 2 (2012)" : 14 Documents clear
Uji Pemanfaatan Daun Binahong (Anredera Cardifolia (Tenore) Steenis) Pada Proses Penyembuhan Luka Gingiva Tikus Wistar (Rattus norvegicus) Melalui Pengamatan Kepadatan Serabut Kolagen Dan Ketebalan Epitel Putri Adriani, Wika; Ardianingtiyas, Idha; Husna Wulansari, Nurul; Nur’aini Safitri, Dian; Primalia AP, Ike; Sih Mahanani, Erlina
Insisiva Dental Journal Vol 1, No 2 (2012)
Publisher : Insisiva Dental Journal

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Rongga mulut sebagai bagian integral tubuh, sering mengalami trauma saat melakukan fungsinya. Trauma ini dapat terjadi secara disengaja maupun tidak, yang pada akhirnya akan menimbulkan luka pada mukosa mulut. Perlukaan pada jaringan akan menyebabkan terjadinyareaksi radang. Reaksi radang merupakan tahap awal dari serangkaian proses penyembuhanluka. Daun Binahong (Anredera cordifolia (Ten.) Steenis) mengandung flavonoid, saponin, dan alkaloid yang dapat berpengaruh pada proses penyembuhan luka. Penelitian ini bertujuan untuk mengetahui uji pemanfaatan daun Binahong (Anredera cardifolia (Ten) Steenis) pada penyembuhan luka di gingiva melalui pengamatan kepadatan serabut kolagen dan ketebalan epitel, serta untuk membandingkan efektifitas penggunaan daun Binahong (Anredera cardifolia (Tenore) Steenis) dan Povidone Iodine pada penyembuhan luka di gingiva. Sampel penelitian menggunakan tikus jantan galur Wistar (Rattus norvegicus) berusia 3 bulan sebanyak 30ekor dibagi menjadi 3 kelompok : kelompok I (kontrol negatif), kelompok II (povidoneiodine), kelompok III (binahong). Tikus yang digunakan dalam penelitian ini memiliki beratbadan 150-250 gram dan telah diadaptasikan selama 1 minggu. Perlakuan dibuat pada gingivarahang bawah dengan luka gores sonde, dengan panjang ± 3mm dan kedalaman hingga tulangalveolar. Luka pada kelompok II diberi Povidon Iodine 1cc, sedangkan pada kelompok III diberi tumbukan binahong 1gram, masing-masing selama 3 menit secara topikal. Dekapitasi dilakukan sesuai hari perlakuan 1, 3,5 hari masing-masing 3 ekor tikus. Penghitungan kepadatanserabut kolagen dilakukan pada preparat histologi Trikom Mallory dan ketebalan epitel dilakukan pada preparat histologi HE. Data kepadatan kolagen dan ketebalan epitel dianalisisdengan One Way Anova dilanjutkan dengan tes LSD untuk mengetahui perbandingan antarkelompok. Hasil tes LSD kepadatan serabut kolagen menunjukkan adanya perbedaan yangbermakna antar kelompok sesuai hari perlakuan. Sedangkan hasil tes LSD ketebalan epitelmenunjukkan adanya perbedaan yang bermakna antara masing-masing kelompok perlakuandibandingkan dengan normal. Namun, tidak ada perbedaan bermakna antar kelompok perlakuan. Penelitian ini mengindikasikan bahwa pemberian tumbukan binahong secara topikaldapat meningkatkan kepadatan kolagen dan ketebalan epitel, sehingga mempercepat prosespenyembuhan luka pada gingiva tikus wistar.
Potensi Ekstrak Etanol Daun Keladi Tikus (Typhonium flagelliforme Lodd.) Sebagai Induktor Apoptosis Sel Kanker Lidah Manusia (SP-C1) Rosyid Ridlo, Himmaturojuli; Supriatno, Supriatno; Medawati, Ana; Driana Rahmawati, Atiek
Insisiva Dental Journal Vol 1, No 2 (2012)
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Typhonium flagelliforme Lodd has been used traditionally to cure breast cancer, lung, colon, rectum, liver, prostate, kidney, cervix, throat, bone, brain, spleen, bladder, leukimia and pancreas cancer. The ethanolic extract of Typhonium flagelliforme Lodd contained active compounds that could inhibit cancer cell growth. One of the active compounds was saponin and phenolic. The aim of study was to examine the potency ethanolic extract of Typhoniumflagelliforme Lodd. as inductor of apoptosis in human oral tongue cancer cell Supris Clone-1 (SP-C1). The desingn of used in this study was pure laboratoris experimental with human oral tongue cancer cells line (SP-C1) as a sample which treated by ethanolic extract of Typhonium flagelliforme Lodd in various concentrations (0, 25, 50, 75, 100, 125 µg/ml) for 48 hours. Apoptosis examination was carrried out by painting with etidium bromide-acridin orange. The result of the study showed that etanolic exstract of Typhonium flagelliforme Lodd. induced apoptotic SP-C1 cell line. Statistical analisis with One Way Anova revealed etanolic extract in various concentration have significant differences (P=0,00) after treated with etanolic extract Typonium flagelliforme Lodd. It also found that the most effective concentration inducing apoptosis of human tongue cancer cells Supris Clone-1 (SP-C1) was the 125 µg/mL. The conclusion of this research, ethanolic extract of Typhonium flagelliforme Lodd. has a potency to induce apoptosis human oral tongue cancer cells (SP-C1).
Oral Habits That Cause Malocclusion Problems Joelijanto, Rudy
Insisiva Dental Journal Vol 1, No 2 (2012)
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Oral habits that place pressure on the teeth may slowly move the teeth out of place. The aim of this study was to review the literature for articles referring the most common oral habits that cause malocclusion. The oral bad habits that cause malocclussion problems include: Thumb sucking, It is a normal habit for babies, but causes serious orthodontic problems if it continues long after the eruption of permanent teeth. Prolonged thumb sucking can create crowded, crooked teeth, or bite problems and speech problems. Protrusion and displacement of front teeth are usual results of thumb sucking. Lip-biting or fingernail biting, both habits can shift the teeth out of alignment. Tongue thrusting, some children thrust their tongue forward, pressing it against the lips with a force that can result in teeth malocclusions such as ‘open bite’ or teeth protrusion (overjet). While parents can not do much to prevent an orthodontic problem caused by hereditary factors, they can help their kids to avoid the need for braces, by maintaining good oral hygiene and avoiding bad oral habits that could cause teeth malocclusion problems. Modern orthodontics are usually able to treat most teeth malocclusions successfully, but prevention can help the family to avoid the large cost of orthodontic treatment and the child will not have to wear dental braces and feel uncomfortable.
Effect Of Apple Juice On Whitening Teeth After Immersion In Coffee Solution In Vitro Puspasari, Nuzulya; Effendi, Chair; Nugraeni, Yuli
Insisiva Dental Journal Vol 1, No 2 (2012)
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The Background of this research because one of the extrinsic cause teeth discoloration is excessive coffee consumption. To cope teeth discoloration whitening teeth done either with chemicals or natural ingredients. Apples (Malus sylvestris Mill) is one of the fruits that contain malic acid, substance that can whitening teeth. The General Objective is to determine the effect of giving apple juice (Malus sylvestris Mill) on a teeth that has been soaked in coffee solution on teeth whitening in vitro. Materials and Methods research is experimental laboratory use elements of the permanent maxillary premolar tooth from extraction indications orthodontic treatment, free of caries and hypoplasia as a sample of 12 pieces, divided into 2 groups. The first group as a control group with 100 ml distilled water immersion. The second group as the treatment group using apple juice immersion with 75% concentration. Samples of tooth element has immersed first in coffee solution during 2 weeks until discoloration then immersed according to the group for 2 weeks (3x@5minutes a day), then measured the color changes of tooth. The Result with Paired T-test showed significant effect on the group before treatment and after treatment (p <0.05). Independen T-test result showed significant difference between the control group immersed in 100 ml distilled water and treatment group, immersed in apple juice 75% concentration. Conclusion of the results showed that apple juice has the ability to whiten the tooth enamel surface that changes color because of immersion in coffee solution so it can return to the original color before discoloration.

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