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INDONESIA
Biomedical Journal of Indonesia
Published by Universitas Sriwijaya
ISSN : 24077097     EISSN : -     DOI : -
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Medicine & Pharmacology
Biomedical Journal of Indonesia is an open access, peer-reviewed journal that focus on basic medical sciences, emphasizing on providing the molecular studies of biomedical problems and molecular mechanisms to integrate researches in all aspects of human health. BJI is dedicated to publishing original research and review articles covering all aspects of biomedical sciences.
Arjuna Subject : Kedokteran - Anatomi
Articles 6 Documents
 1 
Search results for , issue "Vol 5, No 3 (2019)" : 6 Documents clear
EFFECT OF JATI BELANDA LEAVES EXTRACT ON MYELOPEROXIDASE LEVEL IN WISTAR RAT'S LUNG INDUCED CONTUSION PULMONUM Tamzil, Nia Savitri; Lusiana, Evi; Oktariana, Desi
Biomedical Journal of Indonesia Vol 5, No 3 (2019)
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/bji.v5i3.10009

Abstract

Pulmonary contusions are injuries to the lung parenchyma that often result from blunt trauma to the chest wall. This injury will activate the inflammatory response which can produce the effects of oxidative stress so that eventually lung damage occurs. Several studies have identified the effects of Jati Belanda leaves extracts related to the inflammatory process and their effects as antioxidants. This research is an in vivo experimental study with a prepost-test with control group design approach that aims to determine the effectiveness of the extracts of Jati Belanda (Guazuma ulmifolia) in its protection against pulmonary alveolar cells by pretreatment pulmonary contusions. The subjects of this study were white rats (Rattus norvegicus) Wistar strain which were divided into 5 groups namely positive control, negative control, Dutch teak leaf extract 125 mg / kgBB, 250 mg / kgBB and 500 mg / kgBW. Rats were induced by dropping a weight of 400 grams as high as 50 cm. The results of the study of Jati Belanda Leaf Extract (EDJB) all doses and positive control can significantly reduce levels of myeloperoxidase expression (p <0.05). Therefore, it can be concluded that the extracts of Jati Belanda leaves (Guazuma ulmifolia) are all effective doses in reducing the expression of myeloperoxidase in pulmonary tissue of Wistar rats induced by pulmonary contusions.
EVOLUTION OF CARDIOLOGY AS A SPECIALTY Edo Tondas, Alexander; Anwar, Chairil; Agustian, Rolando
Biomedical Journal of Indonesia Vol 5, No 3 (2019)
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/bji.v5i3.9790

Abstract

Science is a conscious effort to try, find and improve human understanding from various aspects in human nature. The number of medical specialties continues to grow until they reach even smaller branches known as sub-specialties. One type of specialization in medical science is the specialization of cardiology, the science that focuses on the needs of the heart organ. The development of cardiology cannot be separated from the history behind it. The progress of cardiology up to this point is a continuous interrelated journey. Every lesson in the past will be a capital for future experience, as will cardiology, where each phase becomes the foundation for future development.
CORRELATION OF PARENTING WITH DELINQUINCY IN JUNIOR HIGH SCHOOL STUDENTS Aini, Syarifah; Rina, khairina; Maramis, Margarita M
Biomedical Journal of Indonesia Vol 5, No 3 (2019)
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/bji.v5i3.10120

Abstract

Juvenile delinquency is a serious problem in all countries. Adolescent involved in delinquency have the potential to be involved in serious criminality. Many factors are thought to be the cause of juvenile delinquency, one of which is family. Parenting is a parent's act of educating their children, especially in providing values and norms that influencing the child development, including antisocial behavior that is associated with delinquency. To analyze the relationship between parenting towards juvenile delinquency in a private junior high school students in Surabaya. An observational cross-sectional analytic study that correlate between parenting towards juvenile delinquency in a junior high school students in Surabaya. The sampling technique is cluster random sampling. To asses the parenting style used the Alabama parenting questionnaire (Parental Authoritory Questionaire). Juvenile delinquency was assessed by Self-Report Delinquincy questionnaire. It was found that 70% of the subjects involved in delinquency with 52.63% experienced authoritative mothering and 66.18% experienced authoritative fathering. There was no significant relationship between mothering towards juvenile delinquency. There was a significant relationship between fathering, especially authoritative fathering towards mild juvenile delinquency and authoritarian fathering towards moderate juvenile delinquency in private junior high school students in Surabaya.Conclusion:There is relationship between parenting and juvenile delinquency.
IFN-GAMMA SECRETION AND IL-10 AFTER STIMULATION OF ESAT-6-CFP-10 (EC610) FUSION ANTIGEN IN PATIENTS WITH ACTIVE TUBERCULOSIS AND LATENT TUBERCULOSIS Prihantika S., Sabrina; Kurniati, Nova; Rahadiyanto, Kemas Ya'kub; Saleh, M Irsan; Hafy, Zen; Tanoerahardjo, Francisca Srioetami; Nugraha, Jusak; Salim, Eddy Mart
Biomedical Journal of Indonesia Vol 5, No 3 (2019)
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/bji.v5i3.8897

Abstract

Tuberculosis (TB) is an infectious disease caused by the bacterium Mycobacterium tuberculosis which is still a health problem in the world including in Indonesia. TB infection arises due to interference with the regulation of the body's defense system. Cellular immune system plays a role in fighting TB infection, namely the role of T lymphocytes that differentiate into Th1 cells secrete pro-inflammatory cytokines IFN-? and Th2 cells that secrete IL-10 anti-inflammatory cytokines. The EC610 fusion antigen is specific and has a strong antigenicity to T cell stimulation. The aim of the study was to determine differences in the mean levels of IFN-? and IL-10 after EC610 antigen stimulation in patients with active TB and latent TB. The design of this study was a quasi-in vitro experiment with PBMC culture stimulated by EC610 antigens in the active TB and latent TB groups. The research and examination were carried out at the South Sumatra Province SSR and the Health Research and Development Laboratory Center, Central Jakarta. There were 21 subjects with active TB and 28 subjects with latent TB who met the inclusion criteria. Measurement of IFN-levels? and IL-10 was performed using ELISA-Reader. The results showed the levels of IFN-? and IL-10 after EC610 antigen stimulation were higher in active TB than latent TB. High levels of IFN-? active TB patients showed protective immune responses against M.tb germs while high levels of IL-10 showed their role as anti-inflammatory. There is no significant difference in the average level of IFN-? in patients with active TB and latent TB (p = 0.769) and there was a significant difference in the level of IL-10 levels after EC610 antigen stimulation was higher in active TB than latent TB (p = 0,000).
UTILIZATION OF ISOFLAVONES WITH BASIC MATERIAL OF ROBUSTA COFFEE SKIN WITH BMD (BONE MARROW DENSITY) MARKERS IN PERI / POST MENOPAUSAL WOMEN Puspita Sari, Ratna Dewi; Bakrie, Samsul
Biomedical Journal of Indonesia Vol 5, No 3 (2019)
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/bji.v5i3.8684

Abstract

The increase in life expectancy of women in Indonesia, which reaches 72 years of age causes almost a third of her life span lived at the time of menopause. The population of menopausal women in Indonesia will increase with all the effects due to decreased estrogen in the form of climatic complaints and an increased risk of bone loss / osteoporosis. The best choice and is the standard treatment for climatic complaints and osteoporosis is hormonal therapy (Estrogen + Progesterone / Estrogen). WHI in 2004 stated that hormone therapy in menopausal women increases the risk of breast cancer. In Indonesia, phytoestrogens are widely circulated in the market with the category of supplements and have been used by the public to deal with climatic complaints and osteoporosis. This phytoestrogen has not been scientifically proven to be useful for overcoming climatic and osteoporotic complaints in postmenopausal women. Phytoestrogens on the market used as Permi III pills contain Red Clover, Black Cohosh and calcium. Some studies say that phytoestrogens for osteoporosis therapy can be obtained from isoflavones derived from robusta coffee skins. This isoflavone can affect bone mineral density in peri / postmenopausal women. The use of phytoestrogens (isoflavones) from the skin of coffee beans affects peri / postmenopausal women and helps maintain and build bone mass (reduce the occurrence of osteoporosis complaints).
EFFECTS OF CIPLUKAN FRUIT EXTRACT (PHYSALLIS PERUVENIA) ON T4 LEVELS IN WHITE RATS Parisa, Nita
Biomedical Journal of Indonesia Vol 5, No 3 (2019)
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/bji.v5i3.9872

Abstract

Hyperthyroidism is a condition where there is an increase in thyroid hormone synthesis and secretion so that the level of thyroid hormone in the blood increases. In 2013, data showed 0.4% of Indonesia's population experienced hyperthyroidism. Ciplukan fruit (Physalis peruviana) is an Indonesian herb that is thought to have an effect on thyroid hormone. This research is an in vivo experimental study. The research subjects were 30 Wistar strain white rats divided into 5 groups: negative control (distilled water), positive control (PTU 100 mg / kgBW), groups 3, 4, and 5 Ciplukan fruit extracts at a dose of 250 mg/kgBW, 500 mg/kgBW, and 1000 mg/kgBW. The results of the examination showed a decrease in T4 levels in the treatment with positive control and administration of ciplukan fruit extracts. There was a difference in the reduction in T4 levels for the group giving ciplukan extract doses of 1, 2, and 3 (p <0.05). It can be concluded that Ciplukan fruit extract with a dose of 250 mg/kgBW, 500 mg/kgBW, and 1000 mg/kgBW has potential as an anti-hyperthyroidism.

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