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All Journal Jurnal Wiyata : Penelitian Sains dan Kesehatan Jurnal Pharma Bhakta
Fathul Hidayatul Hasanah
Institut Ilmu Kesehatan Bhakti Wiyata
Health Professions Medicine & Pharmacology Public Health Social Sciences Other

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STUDY OF PHYTOCHEMICAL COMPOUND CONTENT AND ANALGESIC ACTIVITY OF ETHANOL EXTRAK OF CELERY LEAF (Apium graveolens L.) WRITHING TEST METHOD: STUDY OF PHYTOCHEMICAL COMPOUND CONTENT AND ANALGESIC ACTIVITY OF ETHANOL EXTRAK OF CELERY LEAF (Apium graveolens L.) WRITHING TEST METHOD Rosa Juwita Hesturini; Fathul Hidayatul Hasanah; Dwi Wahyuni; Briandini Dwi Astuti; Anis Anggrayni
JURNAL PHARMA BHAKTA Vol 6 No 1 (2026): Mei (2026)
Publisher : FACULTY OF PHARMACY, INSTITUT ILMU KESEHATAN BHAKTI WIYATA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56710/jpb.v6i1.173

Abstract

Background: The celery plant (Apium graveolens L.) belongs to the Apiaceae family and is one of the vegetable commodities that is widely used for flavoring and decorating dishes with various health benefits. Objective: This study aims to determine the content of phytochemical compounds and analgesic activity of celery leaves. Through a systematic review article. Method: The research method with systematic literature review was carried out by searching for articles or journals related to phytochemical compound content and analgesic activities of celery. which had been published in journals. Literature search was conducted in April-May 2021 through Google Scholar, then journals were selected based on exclusion and inclusion criteria. Conclusions: The inclusion criteria, namely journals published last 5 years, the journal discusses the content of phytochemical compounds and analgesic activity of ethanol extract of celery leaves using the writhing test method. And as for the exclusion criteria, the data in the journal is incomplete and the journal does not discuss the celery plant. Based on the results of a systematic literature review of 5 published journals indicate that celery plant contains phytochemicals flavonoid compounds, tannins, saponins flavor-glucoside (apiin), apigenin and have analgesic activity.
KORELASI KADAR HBA1C DENGAN NILAI RASIO TROMBOSIT LIMFOSIT (RTL) PADA PENDERITA DIABETES MELITUS DI RSUD GAMBIRAN KOTA KEDIRI Okty Indrian Syah; fathul hidayatul hasanah; Sri Wahyuni; Rosa Juwita Hesturini; Panji Ratih Suci; Cikra Ikhda Nur Hamidah Safitri; Fita Sari
Jurnal Wiyata Penelitian Sains dan Kesehatan Vol 13 No 1 (2026)
Publisher : LP2M IIK (Lembaga Penelitian dan Pengabdian Masyarakat Institut Ilmu Kesehatan) Bhakti Wiy

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56710/wiyata.v13i1.1079

Abstract

Latar Belakang: Diabetes melitus (DM) memiliki karakteristik hiperglikemia yang sangat berperan dalam inflamasi sistemik pada komplikasi DM. Rasio Trombosit/Limfosit (RTL) adalah penanda inflamasi pengganti yang dapat mendeteksi disfungsi endotel dan peradangan. Tujuan: Penelitian ini bertujuan untuk mengetahui korelasi kadar HbA1c dengan rasio trombosit/limfosit pada penderita DM. Metode: Penelitian ini menggunakan jenis observasional analitik dan rancangan penelitian cross-sectional serta teknik purposive sampling. Populasi penelitian penderita DM yang diperoleh sebanyak 30 responden dengan kriteria tidak ulkus dan tidak sedang menjalani pengobatan infeksi. Hasil: Berdasarkan uji korelasi Kendall’s tau, didapatkan nilai p = 0,021. Simpulan: Hasil penelitian ini menunjukkan adanya korelasi antara kadar HbA1c dan RTL pada pasien diabetes melitus (DM) di RSUD Gambiran Kota Kediri. Hal ini membuktikan bahwa peningkatan glikasi glukosa akan memicu inflamasi sistemik dan  RTL dapat berfungsi sebagai biomarker pada kasus ini.
Co-Authors Anis Anggrayni Briandini Dwi Astuti cikra ikhda Nur Hamidah safitri Dwi Wahyuni Fita Sari Okty Indrian Syah Panji Ratih Suci Rosa Juwita Hesturini Rosa Juwita Hesturini Sri Wahyuni