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All Journal JURNAL FARMASIMED (JFM) Lumbung Farmasi : Jurnal Ilmu Kefarmasian SOCIAL CLINICAL PHARMACY INDONESIA JOURNAL
Fajar Amirulah
Universitas 17 Agustus 1945 Jakarta
Health Professions Medicine & Pharmacology Public Health Social Sciences

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Effectiveness of the Use of Analgetic Drugs in Sectio Caesarea (SC) Patients at RSAL Mintoharjo Atisi; Fajar Amirulah; Rizky Farmasita Budiastuti; Rangki Astiani
Jurnal FARMASIMED (JFM) Vol 8 No 2 (2026): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/0jfgbm77

Abstract

Cesarean section (CS) is a common obstetric surgical procedure that is frequently associated with moderate to severe postoperative pain, which may delay early mobilization and prolong recovery. This study aimed to evaluate the effectiveness of analgetic use based on the type and number of analgetics on pain intensity and recovery time in post-cesarean section patients at RSAL Mintoharjo. This research was conducted as an observational analytic study with a prospective cohort design involving 80 post-CS patients. Data were collected through medical records, direct observation, and pain assessment using the Numeric Rating Scale (NRS) at 6 hours, 24 hours and on day 2 or 3 postoperatively. Statistical analysis was performed using univariate analysis, Chi-Square test, and one-way ANOVA. The results show that the type of analgesic significantly affects pain intensity at all measurement times (p < 0,05), with combination analgetic regimens providing better pain control that single analgetics. The number of analgetics does not affect pain intensity at 6 hours postoperatively but shows a significant effect at 24 hours and during follow-up interviews. Recovery time is not significantly influenced by the type or number of analgesics, with most patients discharged within three days. Patient age and comorbidities affect pain intensity, while cesarean history and smoking status do not. In conclusion, multimodal analgesia is effective for controlling acute postoperative pain following cesarean section, whereas recovery time is more strongly influenced by patient clinical factors
STUDI DRUG UTILIZATION REVIEW (DUR) TERHADAP PENGGUNAAN ANTIBIOTIK PADA INFEKSI SALURAN PERNAPASAN ATAS Fajar Amirulah
SOCIAL CLINICAL PHARMACY INDONESIA JOURNAL Vol 11, No 1 (2026)
Publisher : Universitas 17 Agustus 1945 Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52447/scpij.v10i2.9411

Abstract

Upper respiratory tract infection (URTI) is a condition characterized by irritation and swelling of the upper respiratory tract without pneumonia, usually accompanied by a cough. According to the Indonesian Ministry of Health, the use of medication can be categorized as rational when the medication given meets the patient's needs. Treatment can only be considered rational if it meets several criteria, namely: the right patient, the right indication, the right drug, the right dose, the right interval of administration, the right duration of administration, and others. The objective of this study is to examine the use of antibiotics for ARI in pediatric patients at Jawilan Health Center. The research method employed is a descriptive method with a cross-sectional design to determine the pattern of antibiotic use for ARI in pediatric patients. Data collection was conducted retrospectively using secondary data obtained from medical records and prescriptions of patients with ARI during the period of May 2024–April 2025 at Puskesmas Jawilan, Serang Regency, Banten. The number of patients was 261 patients aged 1-17 years, diagnosed with ARI and given antibiotics. The most commonly used class of antibiotics was amoxicillin, with 253 administrations (96.9%), followed by cotrimoxazole with 8 administrations (3.1%). The results of the treatment rationality are as follows: correct patient 100%, correct indication 77%, correct drug 100%, correct dosage 86.6%, correct interval of antibiotic administration 100%, and correct duration of antibiotic administration 97.7%. From this research data, it can be concluded that there are still irrational drug administrations below 100% that have long-term effects on the patient's body.
Efektivitas Penggunaan Obat Antikanker Pada Pasien Kanker Serviks di RSUP Fatmawati Tahun 2024 Fajar Amirulah; Azmi Annisa Islamyah; Dini Sari; Farisa Luthfiana
Lumbung Farmasi: Jurnal Ilmu Kefarmasian Vol 7, No 1 (2026): Januari
Publisher : UNIVERSITAS MUHAMMADIYAH MATARAM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/lf.v7i1.37368

Abstract

Kanker serviks merupakan salah satu penyebab utama kematian akibat kanker pada wanita di Indonesia, yang sebagian besar disebabkan oleh rendahnya cakupan deteksi dini dan keterlambatan diagnosis sehingga efektivitas terapi antikanker menjadi kurang optimal. Penelitian ini bertujuan untuk mengevaluasi efektivitas penggunaan obat antikanker berdasarkan respons klinis pada pasien kanker serviks rawat inap di RSUP Fatmawati tahun 2024. Penelitian ini menggunakan pendekatan observasional dengan desain cross-sectional, menggunakan data dari 156 pasien yang memenuhi kriteria inklusi. Hasil penelitian menunjukkan bahwa kemoterapi kombinasi paklitaksel dan sisplatin merupakan jenis terapi yang paling banyak digunakan. Respons klinis terbanyak adalah respons parsial (56,41%) dan respons lengkap (18,59%), menunjukkan efektivitas terapi berdasarkan dominasi respons klinis positif dibandingkan progresi penyakit. Progresi penyakit terjadi pada 17,95% pasien dan penyakit stabil pada 7,05%. Analisis bivariat menunjukkan bahwa hanya stadium kanker yang memiliki hubungan signifikan terhadap respons klinis (p = 0,017). Penelitian ini menyimpulkan bahwa terapi antikanker yang digunakan cukup efektif, terutama pada pasien dengan stadium awal. Pemilihan terapi yang tepat dan deteksi dini menjadi faktor penting dalam meningkatkan keberhasilan pengobatan kanker serviks
Co-Authors Atisi Azmi Annisa Islamyah Dini Sari Farisa Luthfiana Rangki Astiani Rizky Farmasita Budiastuti