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All Journal Journal of Biological Science and Education Jurnal Pengabdian kepada Masyarakat Multidisiplin (JUPENGEN)
Cindy Moyna Clara L.A.
Institut Teknologi Sumatera
Religion Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Economics, Econometrics & Finance Education Engineering

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Phytochemical Compounds of Tropical Plants from Lampung as Antibacterial Agents against Escherichia coli and Staphylococcus aureus: A Literature Review Nadya Syarifatul Fajriyah; Cindy Moyna Clara L.A.
Journal of Biological Science and Education Vol 7, No 2 (2025): December
Publisher : Universitas Sembilanbelas November Kolaka

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31327/jbse.v7i2.2617

Abstract

The growing crisis of antimicrobial resistance has intensified the search for new antibacterial agents, and the diverse tropical flora of Lampung offers a promising natural reservoir of bioactive compounds. This review synthesizes current evidence on plant and algal phytochemicals from Lampung that have been evaluated against two clinically important pathogens, Escherichia coli and Staphylococcus aureus. Following the PRISMA 2020 guidelines, a systematic search conducted on 31 July 2025 using Harzing’s Publish or Perish and databases such as Google Scholar and PubMed identified 200 records. After screening and eligibility assessment, 20 studies published between 2015 and 2025 were included in the analysis. Most investigations employed disc diffusion and minimum inhibitory concentration assays and consistently reported antibacterial activity, with stronger effects generally observed against S. aureus. The predominant classes of active compounds included flavonoids, alkaloids, tannins, saponins, and essential oils. Several species, such as Anredera cordifolia, Mangifera indica peels, Citrus aurantifolia, Syzygium polyanthum, and Cymbopogon nardus, emerged as notable candidates. The findings highlight opportunities for the development of phytopharmaceuticals and natural food preservatives, while key research gaps relate to the limited availability of in vivo data, lack of standardized extraction protocols, and insufficient exploration of molecular mechanisms. Overall, this review underscores the strategic value of Lampung’s biodiversity as a source of potential antibacterial agents effective against E. coli and S. aureus.Keywords: Phytochemicals, Antibacterial activity, Escherichia coli, StaphylococcusAureus, Lampung 
Penguatan Budaya Keselamatan Laboratorium melalui Pelatihan K3 bagi Siswa SMA IT Insan Mulia Boarding School Pringsewu Idra Herlina; Cindy Moyna Clara L.A.; Demi Dama Yanti; Mariyam Mariyam; M. Alvien Ghifari; Ahmad Anggraria Jaya Agung; M. Luqmanul Hakim Habibie
Jurnal Pengabdian Kepada Masyarakat Multi Disiplin Vol. 3 No. 3 (2026): JUPENGEN - Agustus
Publisher : CV. SINAR HOWUHOWU

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70134/jupengen.v3i3.1977

Abstract

School laboratories are essential for developing science process skills; however, their use must be accompanied by consistent occupational safety and health practices. This community service program aimed to improve students’ understanding and awareness of laboratory safety culture at SMA IT Insan Mulia Boarding School Pringsewu. The program involved coordination with the partner school, preparation of training materials and evaluation instruments, and an interactive training session on 14 April 2026. The materials covered basic laboratory safety, the 5R principles, hazard identification, simple risk assessment, and appropriate use of personal protective equipment. Evaluation was conducted descriptively by comparing the mean pre-test and post-test scores and observing participant engagement. The mean score increased from 86.60 to 90.50, representing a 3.90-point or 4.50% improvement. Participants also engaged actively in case discussions and demonstrated a better understanding of safe work behaviour. The school’s support in providing the venue, participants, and documentation strengthened implementation. The training offers an initial foundation for integrating safe working habits into routine school laboratory activities.
Co-Authors Ahmad Anggraria Jaya Agung Demi Dama Yanti Idra Herlina M. Alvien Ghifari M. Luqmanul Hakim Habibie Mariyam Mariyam Nadya Syarifatul Fajriyah