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Sumardi
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Korelasi Konsumsi Sidaguri dengan Kadar Asan Urat Darah Suprianto Suprianto; Adek Chan; Joko Wibowo; Samran; Sumardi; Debi Meilani
Jurnal Indah Sains dan Klinis Vol 6 No 1 (2025): Jurnal Indah Sains dan Klinis
Publisher : Yayasan Penelitian dan Inovasi Sumatera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52622/jisk.v6i1.02

Abstract

Background: Hyperuricemia as an indicator of increased blood uric acid. The prevalence rate in Indonesia is not recorded with certainty. However, the prevalence of gout reached 655,745 people out of 238,452,952 people in Indonesia, ranking first in Southeast Asia. Sidaguri flavonoids have inhibitory power against Xanthine Oxidase so that they can reduce uric acid. Objective: The study was aimed at detecting the effect and correlation of Sidaguri capsule consumption (Sida rhombifolia L) on reducing uric acid in patients. Method: The study was conducted Pretest and Posttest on 22 patients with hyperuricemia with the Easy Touch GCU Instrument. Results: The results showed that the average uric acid level before the intervention was 8.37 mg/dL and after the intervention was 6.57 mg/dL. Conclusion: Sidaguri capsules have an effect on reducing uric acid levels in patients
Formulasi Sediaan Lotion Antioksidan Ekstrak Daun Sirsak (Annona muricata L.) dan Ekstrak Kulit Buah Naga Merah (Hylocereus polyrhizus) sebagai Pelembab Sumardi; Suprianto; Innayah Azzahra; Lisa Syafrida
Jurnal Indah Sains dan Klinis Vol 6 No 3 (2025): Jurnal Indah Sains dan Klinis
Publisher : Yayasan Penelitian dan Inovasi Sumatera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52622/jisk.v6i3.05

Abstract

Background: A lotion made from ethanol extracts of Sirsak (Annona muricata) leaves and Naga Merah fruit (Hylocereus polyrhizus) peels is a potential antioxidant moisturizer, but its quality, safety, and hydration effect need confirmation. Objective: To formulate five oil-in-water lotions with different extract ratios (total extract 3% w/w) and evaluate physical quality, preliminary safety, and moisturizing performance. Method: The formulations were tested for organoleptic properties, homogeneity, pH, and spreadability. A simple irritation test and a three-day forearm hydration assessment using a skin analyzer were conducted in 25 panelists, followed by one-way analysis of variance. Results: All formulations had pH 6.67–6.96, with minor inhomogeneity observed in one formulation. Acceptable spreadability was achieved by three formulations under specific loads. No irritation occurred. All formulations increased hydration, with significant differences between them (p < 0.001); the two best-performing formulations produced the highest and most stable moisture over three days. Conclusion: The combined-extract oil-in-water lotion at 3% w/w is feasible and preliminarily safe, and the two top formulations are recommended for further development
Co-Authors Adek Chan Debi Meilani Innayah Azzahra Joko Wibowo Lisa Syafrida Samran, Samran Suprianto Suprianto Suprianto