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All Journal E-Jurnal Medika Udayana Jurnal Ilmu Kedokteran dan Kesehatan Heart Science Journal
Pintaningrum, Yusra
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Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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HUBUNGAN ANTARA MPV (MEAN PLATELET VOLUME) DENGAN LUAS INFARK MIOKARD PADA PASIEN STEMI (ST-SEGMENT ELEVATED MYOCARDIAL INFARCTION) YANG DIUKUR BERDASARKAN SKOR QRS SELVESTER Bagus Kantwa Abhimantra, Gede; Rahmat, Basuki; Pintaningrum, Yusra
E-Jurnal Medika Udayana Vol 11 No 7 (2022): E-Jurnal Medika Udayana
Publisher : Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/MU.2022.V11.i7.P13

Abstract

Background: Globally heart disease occupy the first order of mortality population in the world. Acute myocardial infarction is one of them, in its classification AMI can be divided into STEMI and NSTEMI. Pathological changes in AMI will involve many things, one of them is platelets. The aim of the study is to know the correlation between Mean Platelet Volume (MPV) and the myocardial infarction size in STEMI patient based on QRS Selvester score. Methods: This study was an observational analytic study with a cross sectional approach. This research was conducted in July 2020-March 2021 at the Rumah Sakit Umum Kota Mataram, involving 63 subjects. Data obtained from patient medical records using non-probability sampling technique which is consecutive sampling. Results: From 63 data, there are 50 male patients and 13 female patients, the average of the patients age is 57.97 years old. MPV mean is 8.77 fL and the mean of myocardial infarction size is 25.33%. The data scale of the two variables is numerical for MPV and numerical for the myocardial infarction size. The normality test was performed using the Kolmogorov-Smirnov test and the MPV significance value was 0.200 and the myocardial infarction size was 0.200 (normal distribution). Pearson correlation test results obtained p=0.885 (p> 0.05). Conclusion: There is no significant correlation between the MPV and the myocardial infarction size.
The Predictors of Spontaneous Coronary Reperfusion in Patients with ST-segment Elevation Myocardial Infarction Ermawan, Romi; Pintaningrum, Yusra; Sari, Dian Puspita; Indrayana, Yanna; Aprilia, Kartika
Heart Science Journal Vol. 5 No. 3 (2024): The Science and Art of Revascularization in Acute Coronary Syndrome
Publisher : Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub/hsj.2024.005.03.6

Abstract

BACKGROUND: In ST-segment elevation myocardial infarction (STEMI) management, some patients undergo spontaneous coronary reperfusion (SCR) with a better prognosis than those without SCR, but predictors for SCR remain unclear.OBJECTIVE: To investigate several potential predictors of SCR, including smoking status, BMI, DAPT loading time, hemoglobin levels, platelet count, random blood sugar levels, uric acid levels, creatinine clearance, and the Syntax score.METHODS: This case-control study was conducted at the West Nusa Tenggara General Hospital in Indonesia from December 2022 to September 2023. Data collection encompassed various patient demographics and clinical parameters, including name, medical record number, age, gender, smoking status, BMI, DAPT loading time, hemoglobin levels, platelet count, random blood sugar, uric acid, creatinine clearance, the Syntax score, and the occurrence of SCR. Statistical analysis for this study involved multivariate logistic regression analysis.RESULTS: A total of thirty-two patients was included, evenly divided into 16 subjects allocated to the SCR group and 16 to the non-SCR group. The analysis indicated that only BMI demonstrated a statistically significant association with SCR occurrence. However, the study did not yield conclusive evidence regarding the influence of smoking status, DAPT loading time, hemoglobin levels, platelet count, random blood sugar levels, uric acid levels, creatinine clearance, and the Syntax score on the likelihood of SCR.CONCLUSION: A normal BMI is identified as a robust predictor for the incidence of SCR in patients diagnosed with STEMI.
Predictors of right subclavian artery tortuosity in trans-radial coronary angiography access Ermawan, Romi; Pintaningrum, Yusra; Rahmat, Basuki; Putra, AASM Meiswaryasti; Indrayana, Yanna
Heart Science Journal Vol. 6 No. 3 (2025): Advancements in Cardiac Imaging : Unlocking New Perspectives on the Heart Visua
Publisher : Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.hsj.2025.006.03.13

Abstract

BACKGROUND: Trans-radial access has become the new standard and is increasingly in demand in coronary angiography. However, this method can fail due to tortuosity of the right subclavian artery. OBJECTIVES: This study aims to identify the predictors of right subclavian artery tortuosity. METHODS: This retrospective case-control study was conducted at two of the largest hospitals in West Nusa Tenggara, Indonesia. All research data were obtained from secondary sources, including video recordings of coronary angiographies, angiography reports, and patient medical records. Predictors included age, gender, smoking, height, body mass index, hypertension, diabetes mellitus, systolic and diastolic blood pressure, and random blood sugar. RESULTS: The study involved 80 subjects, divided into right subclavian artery tortuosity and normal group, with 40 subjects each. The prevalence of tortuosity was 8.1%, while the success rate of trans-radial access was 70.0%. Four significant predictors were identified: smoking (adjusted OR 0.26; p = 0.019), hypertension (adjusted OR 4.83; p = 0.020), diastolic blood pressure (adjusted OR 1.05; p = 0.044), and body mass index (adjusted OR 1.16; p = 0.035). The optimal cutoff points were determined to be a body mass index of ≥ 24.4 (sensitivity 60.0%; specificity 60.0%; p = 0.006; AUC = 0.665) and diastolic blood pressure of ≥ 78.5 mmHg (sensitivity 67.5%; specificity 67.5%; p = 0.002; AUC = 0.685). CONCLUSION: This study has identified smoking, hypertension, diastolic blood pressure, and body mass index as significant predictors of right subclavian artery tortuosity in trans-radial coronary angiography access. 
STUDI LITERATUR : PATOFISIOLOGI, DIAGNOSIS DAN PENATALAKSANAAN KOLITIS ULSERATIF Abiyyu, Muhammad Farras; Irawan, Muhammad R; Safitri, Nasywa A; Meta S B Duarsa, Ni Made; ’rifatullah, Nurma; Pintaningrum, Yusra
Jurnal Ilmu Kedokteran dan Kesehatan Vol 10, No 12 (2023): Volume 10 Nomor 12
Publisher : Prodi Kedokteran Fakultas Kedokteran Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/jikk.v10i12.12543

Abstract

Abstrak: Studi Literatur: Patofisiologi, Diagnosis Dan Penatalaksanaan Kolitis Ulseratif. Kolitis ulseratif merupakan penyakit kronis dengan insidensi hampir sebagian besar dari populasi dunia. Penyakit ini mempengaruhi usus besar dengan menimbulkan relaps dan peradangan pada mukosa yang dapat meluas dari rektum hingga bagian proksimal usus besar. Kolitis ulseratif dapat terjadi baik pada pria dan wanita dengan insidensi terbanyak pada rentang usia 30-40 tahun. Kolitis ulseratif disebabkan karena adanya defek dari lapisan epitel, respon imun dan keterlibatan dari mikroflora di kolon. Manifestasi klinis yang dapat ditemukan dari kolitis ulseratif adalah diare, nyeri perut, tenesmus, hematochezia dan ditemukan darah serta lendir pada feses. Diagnosis dari kolitis ulseratif biasanya dibandingkan dengan penyakit crohn karena keduanya termasuk dalam penyakit yang menyebabkan peradangan pada usus atau dikenal dengan Inflammatory Bowel Disease (IBS). Prognosis dari kolitis ulseratif sekitar 10% serangan awal dapat berkembang dan mengakibatkan komplikasi serius, 10% lainnya dapat sembuh sepenuhnya setelah satu kali serangan dan sisanya lagi bisa mendapatkan rekurensi dari penyakit ini. Dalam penatalaksanaan kolitis ulseratif, dapat bergantung dari tingkat keparahan penyakit.
Sindrom Koroner Kronik: Diagnosis yang Tepat Berdasarkan Pedoman Terbaru Pintaningrum, Yusra; Harliza, Baiq Fanindya; Gifari, Lalu Maulana Azmi; Arsy, Lazuardi; Rahman, Moch. Aulia; Saraswati, Ni Wayan Citra Ayu; Dwi putri, Adelya Rahma; Girsang, Andrew Deardo Purba; Exhasna, Artiani Tresna Imut; Syafitri, Bq. Annisa Salmaadani; Abdurrrosyid, Muhammad
Jurnal Ilmu Kedokteran dan Kesehatan Vol 11, No 6 (2024): Volume 11 Nomor 6
Publisher : Prodi Kedokteran Fakultas Kedokteran Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/jikk.v11i6.14515

Abstract

Penyakit Jantung Koroner (PJK) merupakan salah satu penyakit kardiovaskuler yang sering menyebabkan kematian di seluruh dunia. PJK memiliki patofisiologi dinamis, yang membaginya menjadi dua kategori manifestasi klinis yaitu Sindrom Koroner Akut (SKA) dan Sindrom Koroner Kronik (SKK). Metode: Artikel ini merupakan sebuah tinjauan Pustaka dari berbagai sumber kepustakaan elektronik yang dirangkum menjadi sebuah artikel ilmiah tinjauan Pustaka. Hasil dan Pembahasan: European Society of Cardiology (ESC) mendefinisikan SKK sebagai tahapan-tahapan evolusioner yang berbeda dari berkembangnya PJK, namun tidak termasuk manifestasi klinis dari SKA. Penyakit ini memiliki gejala angina pektoris atau nyeri dada yang dapat diprediksi akibat dari iskemia miokardium, stress emosional, dan stres fisik. Diagnosis dan penggolongan dari risiko penyakit pada pasien SKK penting untuk dilakukan agar dapat membantu dalam pencegahan SKA.
Co-Authors Abdurrrosyid, Muhammad Abiyyu, Muhammad Farras Aprilia, Kartika Bagus Kantwa Abhimantra, Gede Basuki Rahmat Masdi Siduppa Dian Puspita Sari Dwi putri, Adelya Rahma Exhasna, Artiani Tresna Imut Gifari, Lalu Maulana Azmi Girsang, Andrew Deardo Purba Harliza, Baiq Fanindya Indrayana, Yanna Irawan, Muhammad R Lazuardi Arsy, Lazuardi Meta S B Duarsa, Ni Made Putra, AASM Meiswaryasti Rahman, Moch. Aulia Romi Ermawan, Romi Safitri, Nasywa A Saraswati, Ni Wayan Citra Ayu Syafitri, Bq. Annisa Salmaadani ’rifatullah, Nurma