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Journal : Jurnal Biologi Tropis

Relationship of Comorbidity and Age to the Severity of Clinical Symptoms of COVID-19 at Mataram University Hospital I Made Arya Yogiswara Mahayasa; Moulid Hidayat; Prima Belia Fathana; Indana Eva Ajmala
Jurnal Biologi Tropis Vol. 23 No. 1 (2023): January - March
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v23i1.4581

Abstract

COVID-19 disease is a disease that arises due to infection with the Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2). The purpose of this study was to determine differences in clinical symptoms in elderly and non-elderly patients, as well as patients who had comorbidities and did not have comorbidities. This research is a type of cross-sectional study that was conducted by reviewing the medical records of COVID-19 patients undergoing treatment at Mataram University Hospital in 2021. Data was collected using a consecutive sampling technique. The statistical test used is the Chi-square comparative test. To assess the relationship of age and comorbidities to the severity of symptoms in COVID-19 patients. In this study, 86 subjects were selected based on the inclusion and exclusion criteria applied. The majority of subjects were in the 15-59 year age group, namely 66 (23.3%). With male sex 51 (60.5%) people. The majority of patients with comorbidities experienced severe/critical symptoms 16 (44.4%) and patients without comorbids experienced no symptoms or experienced mild symptoms 35 (35%). The majority of elderly patients experienced severe-critical symptoms 9 (45%) and the majority of non-elderly patients experienced no symptoms or experienced mild symptoms 42 (63.6%). The results of the bivariate analysis test showed a p-value = 0.001 for comorbids with severe symptoms, and a p-value = 0.003 for age with severe symptoms. There is a significant relationship between comorbidities and age on the severity of symptoms in COVID-19 patients.
Differences in RDW Values of COVID-19 Patients with Pneumonia and Without Pneumonia at RSUM and RSUDP NTB Indri Setiawati; Moulid Hidayat; Rina Lestari
Jurnal Biologi Tropis Vol. 23 No. 1 (2023): Special Issue
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v23i1.5849

Abstract

Pneumonia coinfection in COVID-19 patients can be an important risk factor for patient mortality. Red blood cell distribution width (RDW) is a predictor that can determine clinical outcomes in patients with respiratory tract infections and serious illnesses, so researchers want to conduct research to determine the difference in RDW values in COVID-19 patients with and without pneumonia at RSUM and RSUDP NTB. The design of this research is cross sectional. The sampling technique used was consecutive sampling. There were 110 COVID-19 patient data used in this research. Data collection uses medical record notes. The statistical analysis used was the Mann-Whitney test. The average age of patients was 48 years ± 16 years. Most of the subjects were male (53.6%). The most common comorbidity was diabetes mellitus (21.8%). The average RDW values in COVID-19 patients with and without pneumonia were 13.9% and 13.1%. The difference in the mean RDW value in the two groups is 0.8%. This study found that clinically there were differences in the RDW values of COVID-19 patients with pneumonia and without pneumonia at RSUM and RSUDP NTB.
ARDS (Acute Respiratory Distress Syndrome) in Pediatric and Adult Zulfa Hasyimiyyah Ihtisyam; Latifah Mukhlisatunnafsi; M. Fardi Anugrah; Moon Fahira; Putu Diwyandaani Priyahita; Theophany Margareta Kurniawan; Moulid Hidayat
Jurnal Biologi Tropis Vol. 23 No. 1 (2023): Special Issue
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v23i1.5767

Abstract

Acute Respiratory Distress Syndrome (ARDS) is a serious medical condition that occurs when lungs become severely inflamed, which inhibits the ability to take in the oxygen and eliminate carbon dioxide. The purpose of this article is to find out more about the clinical manifestation, pathophysiology, diagnosis, and treatment of ARDS. The literatures that used for this literature review are from National Center for Biotechnology Information (NCBI), Google scholar, and Proquest. The result for this literature review is the development of ARDS is associated with inflammation in lung’s epithelium, endothelium, and interstitium which consist three phases which is exudative, proliferative, and fibrotic phases. The Berlin Criteria issued by the American-European Consensus Conference (AECC) in 2021 used for ARDS diagnosis. The treatments for ARDS could used pharmacotherapy and non-pharmacotherapy.