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All Journal Obat: Jurnal Riset Ilmu Farmasi dan Kesehatan SALUT: Journal of Social and Education
Puji Elok Dzakirah
Universitas Mataram
Humanities Education Health Professions Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Nursing Public Health Social Sciences Other

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Efektivitas Penggunaan Obat Golongan Statin terhadap Pasien Penyakit Jantung Koroner Puji Elok Dzakirah; Karlina Dwi Febrianingsih; Baiq Haura Audina Ananta Putri; Khairinna Rifa Andira; Nanda Putri Utami Aziz; Sabila Rosyada; Tuhfatul Ulya
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 4 No. 5 (2026): September : OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v4i5.2373

Abstract

Coronary heart disease (CHD) is one of the leading causes of mortality worldwide and is closely associated with dyslipidemia, particularly elevated low-density lipoprotein (LDL) levels. Statins are recommended as first-line therapy to reduce LDL levels and lower the risk of cardiovascular events in patients with CHD. This literature review aimed to evaluate the effectiveness of statin therapy in patients with coronary heart disease. A literature search was conducted using Google Scholar between May 14 and May 29, 2025, with the keywords "statin drugs," "statin effectiveness," "coronary heart disease," and "LDL reduction." Articles were selected based on predetermined inclusion and exclusion criteria, resulting in ten eligible studies. The review showed that atorvastatin was the most frequently prescribed statin and consistently demonstrated effectiveness in reducing LDL levels by approximately 30–50%, increasing HDL levels, and lowering cardiovascular risk. Simvastatin was also effective in managing dyslipidemia, although several studies reported lower effectiveness compared with atorvastatin. Furthermore, a combination of rosuvastatin 10 mg and ezetimibe 10 mg was reported to be more effective in achieving LDL-C targets than high-intensity statin monotherapy in patients at very high cardiovascular risk. Overall, statins are effective for the management of coronary heart disease, with atorvastatin showing the most consistent therapeutic benefits.
Implementasi Nilai-Nilai Pancasila dalam Pembentukan Etika Profesi Apoteker di Indonesia Nindya Kamila Putri Ashari; Nadia Magfira Nurmalasanti; Halimatussakdiyah; Nida Fadwa Nabila; Puji Elok Dzakirah
Journal of Social and Education Vol. 3 No. 1 (2026): Journal of Social and Education
Publisher : Lembaga Riset dan Publikasi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.66909/lrp.salut.v3i1.308

Abstract

Pancasila sebagai dasar negara dan ideologi bangsa berfungsi sebagai pedoman moral dan landasan etika bagi seluruh profesi, termasuk profesi kefarmasian. Penelitian ini menggunakan metode studi literatur dengan menelaah berbagai sumber ilmiah nasional periode 2015–2025, seperti jurnal, buku, dan dokumen organisasi profesi kefarmasian. Hasil kajian menunjukkan bahwa setiap sila Pancasila memiliki kontribusi penting dalam membentuk karakter apoteker yang profesional, berintegritas, dan berorientasi pada kemanusiaan. Sila Ketuhanan menumbuhkan tanggung jawab spiritual dalam praktik kefarmasian; sila Kemanusiaan menekankan empati dan perlakuan adil terhadap pasien; sila Persatuan mendorong kolaborasi lintas profesi; sila Kerakyatan menumbuhkan partisipasi dalam pengambilan kebijakan kesehatan; dan sila Keadilan Sosial menegaskan pemerataan akses layanan obat bagi seluruh masyarakat. Selain itu, keseimbangan antara hak dan kewajiban apoteker menjadi wujud nyata dari prinsip keadilan dan kemanusiaan. Namun, implementasi nilai-nilai Pancasila masih menghadapi tantangan, seperti konflik kepentingan, tekanan ekonomi, dan lemahnya pengawasan etika. Oleh karena itu, diperlukan penguatan pendidikan etika partisipatif dan peran aktif organisasi profesi seperti Ikatan Apoteker Indonesia (IAI) untuk menanamkan nilai-nilai Pancasila secara berkelanjutan. Penerapan nilai-nilai tersebut diharapkan mampu memperkuat profesionalisme, tanggung jawab sosial, serta kepercayaan masyarakat terhadap profesi apoteker di Indonesia.
Co-Authors Baiq Haura Audina Ananta Putri Halimatussakdiyah Karlina Dwi Febrianingsih Khairinna Rifa Andira Nadia Magfira Nurmalasanti Nanda Putri Utami Aziz Nida Fadwa Nabila Nindya Kamila Putri Ashari Sabila Rosyada Tuhfatul Ulya