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All Journal JOURNAL OF Pharmacy and Tropical Issues
Agung Dewantoro
Stikes Widya Dharma Husada Tangerang
Medicine & Pharmacology

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Formulasi sediaan lotion kombinasi ekstrak wortel (Daucus carota), stroberi (Fragaria x ananassa), dan apel (Malus domestica) Bheta Sari Dewi; Sheila Meitania Utami; Ahmad Sopian; Agung Dewantoro; Ayu Werawati
JOURNAL OF Pharmacy and Tropical Issues Vol. 6 No. 2 (2026): June Edition 2026
Publisher : Indonesian Public Health-Observer Information Forum (IPHORR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56922/pti.v6i2.3072

Abstract

Background: The combination of plant extracts is known to have the potential to provide a synergistic effect that can increase the effectiveness of protection against oxidative stress and skin aging. Purpose: To formulate and evaluate a lotion preparation containing a combination of carrot, strawberry, and apple extracts as a source of natural antioxidants for skin care. Method: This study used six lotion formulas (FI–FVI) with varying concentrations of carrot extract (1%, 3%, 5%) combined with 0.5% apple, and strawberry extract (0.5%, 1%, 2%) combined with 0.5% apple. Physical evaluation included organoleptic tests, homogeneity, pH, spreadability, adhesiveness, and viscosity during 1 week of storage at room temperature. Antioxidant activity was measured by the DPPH method and total flavonoid content was determined by UV-Vis spectrophotometry. Results: All formulas were physically stable with pH 7.01–7.15, spreadability 5.2–7.5 cm, adhesiveness >4 seconds, and viscosity 11.200–13.900 cP. The highest antioxidant activity and highest flavonoid content were obtained in FVI (Strawberry 2% + Apple 0.5%) with IC50 value of 96.90 ppm (strong category) and flavonoid content of 16.04%. Conclusion: The lotion formulation combining carrot, strawberry, and apple extracts has good physical stability and potential antioxidant activity for skin care.   Keywords: Antioxidant; Apple; Carrot; Flavonoid; Lotion; Strawberry.
Co-Authors Ahmad Sopian Ayu Werawati Bheta Sari Dewi Sheila Meitania Utami