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FORMULASI DAN EVALUASI FISIK SEDIAAN SERUM ANTI-AGING YANG MENGANDUNG EKSTRAK TANAMAN DARI BERBAGAI LITERATUR Bheta Sari Dewi; Ayu Werawati
KOLONI Vol. 1 No. 4 (2022): DESEMBER 2022
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/koloni.v1i4.426

Abstract

Currently, beauty products are developing very fast, especially anti-aging facial care products. One of the most popular products is serum. Serum contains many concentrates that are useful for nourishing and moisturizing the skin. Several plants that have been studied have the potential to be used as serum preparations, namely apuh-apuhan leaves, brown rice, Malacca fruit, gotu kola, jamblang leaves, cempedak leaves, black pepper, and Perilla Frutescens. This study aims to determine the formulation and physical evaluation of serum preparations containing plant extracts in terms of various literatures. The method used is descriptive literature review by collecting various sources from several national journals. The number of national journals used is 7 and 1 international journal. The results of a literature study on serum formulations containing plant extracts can be formulated into serum dosage forms. Evaluation of serum preparations includes organoleptic tests, pH tests, spreadability tests, and viscosity tests. The results of the study concluded that the formulation with the most complete physical evaluation and had good stability without any signs of damage to the dosage form in the serum formulation with a pH value of 5.5, a spreadability of 6.63 cm and a viscosity value of 2900 cP were found in formulations containing the extract. malacca fruit plants. Keywords: anti-aging, serum, formulation, evaluation, extract
EVALUASI WAKTU TUNGGU PELAYANAN RESEP POLIKLINIK ANAK RAWAT JALAN DI RUMAH SAKIT CIPUTRA CITRA RAYA TANGERANG PERIODE JANUARI - MARET 2022 Suny Koswara Rahajeng; Humaira Fadhilah; Bheta Sari Dewi; Anis Dwi Kristiyowati; Euis Sumiati
PHRASE (Pharmaceutical Science) Journal Vol 3, No 1 (2023): Pharmaceutical Science Journal Vol 3 No 1, 2023
Publisher : Sekolah Tinggi Ilmu Kesehatan Widya Dharma Husada Tangerang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52031/phrase.v3i1.511

Abstract

ABSTRAK Tujuan dari penelitian yang berjudul “Evaluasi Waktu Tunggu Pelayanan Resep Poliklinik Anak Rawat Jalan Di Rumah Sakit Ciputra Citra Raya Tangerang Periode Januari - Maret 2022” yaitu untuk mengetahui rata – rata waktu tunggu pelayanan resep rawat jalan di rumah sakit Ciputra Citra Raya Tangerang periode Januari - Maret 2022. Metode: Penelitian ini merupakan penelitian deskriptif dengan metode cross-sectional, dengan populasi dan sampel adalah semua resep pasien rawat jalan poliklinik anak yang dilayani di Instalasi Farmasi Ciputra Hospital Citra Raya Tangerang periode Januari – Maret 2022. Proses pengolahan data yang dilakukan pada penelitian ini terdiri dari coding, editing, entry, dan cleaning. Sedangkan analisis data dilakukan dengan analisis univariat terhadap tiap variable hasil penelitian. Hasil rata-rata waktu tunggu pelayanan resep poliklinik anak rawat jalan dengan standar mutu pelayanan di Ciputra Hospital Citra Raya Tangerang yang telah memenuhi Standar Pelayanan Minimal Rumah Sakit sebanyak 356 resep, (91,9%) yang terdiri dari 327 resep obat non racikan (≤ 15 menit), sedangkan (8.1%) yang tidak sesuai Standar Pelayanan Minimal Rumah Sakit sebanyak 29 resep obat non racikan (≥ 15 menit), dan Rata-rata waktu tunggu total dari seluruh sampel untuk obat racikan di periode Januari - Maret 2022 memiliki rata-rata selama 17.23 menit. Waktu tunggu pelayanan resep racikan poliklinik anak rawat jalan dengan standar mutu pelayanan di Ciputra Hospital Citra Raya Tangerang yang telah memenuhi Standar Pelayanan Minimal Rumah Sakit sebanyak 356 resep, (91%) yang terdiri dari 324 resep obat racikan (≤ 30 menit), sedangkan (9%) yang tidak sesuai Standar Pelayanan Minimal Rumah Sakit sebanyak 32 resep obat racikan (≥ 30 menit). 
KESESUAIAN PENYIMPANAN GOLONGAN NARKOTIKA DAN PSIKOTROPIKA DI FARMASI RUMAH SAKIT X DAERAH KEBAYORAN BARU JAKARTA SELATAN sayyidah sayyidah; Agung Dewantoro; Bheta Sari Dewi; Ahmad Sopian
PHRASE (Pharmaceutical Science) Journal Vol 2, No 1 (2022): PHRASE (PHARMACEUTICAL SCIENCE) JOURNAL VOL 2 NO 1 (2022)
Publisher : Sekolah Tinggi Ilmu Kesehatan Widya Dharma Husada Tangerang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52031/phrase.v2i1.182

Abstract

The hospital is one of the facilities that provide health services in an effort to maintain, improve health, prevent disease, cure disease, and recovering. Pharmaceutical services in hospitals have standards that must be met, namely regarding clinical pharmacy services and drug management. The formulation of the problems in this research are: How is the level of suitability for storing narcotics and psychotropic drugs at the Pertamina Central Hospital (RSPP) based on the Regulation of the Minister of  Health Number 3 of  2015. This research uses a descriptive type, which is the most basic form of research. Intended to describe existing phenomena. This research examines the forms, activities, characteristics, changes, relationships, similarities, and differences between them and other phenomena. The results of this study indicate that the suitability of narcotics and psychotropic drugs is said to be good, the death stock of narcotics and psychotropic drugs is said to be good. The percentage of narcotics and psychotropic drugs that are expired or damaged are said to be good. The suitability of the Narcotics and Psychotropic drug dispensing system is not 100% FIFO and FEFO. The psychotropic storage system at the Pertamina Central Hospital Pharmacy Installation has met the Storage Standards based on the guidelines for the management of Hospital Pharmaceutical Supplies and the Regulation of the Minister of Health of the Republic of Indonesia Number 3 of 2015.
STUDI LITERATUR KHASIAT KOMBINASI EKSTRA HERBA PEGAGAN DAN EKSTRAK DAUN LIDAH BUAYA SEBAGAI ANTIAGING Dewi, Bheta Sari; Werawati, Ayu
Edu Masda Journal Vol 7, No 1 (2023): Edu Masda Journal Volume 7 Nomor 1
Publisher : STIKes Kharisma Persada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52118/edumasda.v7i1.182

Abstract

Traditional herbs have been used for thousands of years for medicinal and skin care purposes. Several types of old ingredients are known for their anti-aging properties, such as Centella asiatica L herb extract and Aloe vera L leaf extract. Both are known for their beneficial properties in maintaining healthy and beautiful skin, including antioxidant, anti-inflammatory and regenerative effects. This study aims to evaluate the efficacy of a combination of gotu kola herb extract and aloe vera herb extract as an antiaging herb. Therefore, the two extracts need to look for related references. This research method involved studying the literature from articles and scientific journals related to the efficacy of  Centella asiatica L herb extract and aloe vera leaf extract as antiaging. The data were analyzed and compiled in the form of a literature synthesis. The results of this study indicate that the combination of gotu kola herb extract and aloe vera herb extract can have beneficial properties in antiaging skin care. The combination of these two herbs can help increase the production of collagen and elastin in the skin, which can help reduce signs of aging such as wrinkles and fine lines. Apart from that, both are also known for their properties which can help protect the skin from sun damage and other environmental factors. ABSTRAKHerbal tradisional telah digunakan sejak ribuan tahun yang lalu untuk tujuan pengobatan dan perawatan kulit. Beberapa jenis bahan lama terkenal dengan khasiat antiagingnya, seperti ekstrak herba pegagan (Centella asiatica L) dan ekstrak daun lidah buaya (Aloe vera L). Keduanya dikenal karena sifat-sifatnya yang bermanfaat dalam menjaga kesehatan dan kecantikan kulit, termasuk efek antioksidan, antiinflamasi, dan regeneratif. Penelitian ini bertujuan untuk mengevaluasi khasiat kombinasi ekstrak herba pegagan dan ekstrak herba lidah buaya sebagai antiaging . Oleh karena itu, kedua ekstrak tersebut perlu dicari referensi terkait. Metode penelitian ini melibatkan studi literatur dari artikel-artikel dan jurnal ilmiah terkait dengan khasiat ekstrak herba pegagan dan ekstrak daun lidah buaya sebagaiantiaging. Data dianalisis dan disusun dalam bentuk sintesis literatur. Hasil dari penelitian ini menunjukkan bahwa kombinasi ekstrak herba pegagan dan ekstrak daun lidah buaya dapat memiliki khasiat yang bermanfaat dalam perawatan kulit antiaging. Kombinasi kedua ekstrak ini dapat membantu meningkatkan produksi kolagen dan elastin dalam kulit, yang dapat membantu mengurangi tanda-tanda penuaan seperti keriput dan garis halus. Selain itu, keduanya juga dikenal karena sifat-sifatnya yang dapat membantu melindungi kulit dari kerusakan akibat sinar matahari dan faktor lingkungan lainnya.
FORMULASI DAN UJI AKTIVITAS ANTIBAKTERI SEDIAAN HIDROGEL EKSTRAK ETANOL DAUN KELOR Werawati, Ayu; Dewi, Bheta Sari; Hasanah, Uswatun; Aulia, Gina; Zahra, Annisa Fairuz
Edu Masda Journal Vol 8, No 2 (2024): EDU MASDA JOURNAL
Publisher : STIKes Kharisma Persada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52118/edumasda.v8i2.231

Abstract

Acne vulgaris is an inflammatory skin disease that is widespread in 85% of the human population. This disease occurs when hair follicles are blocked by dead skin cells. In some cases, bacteria such as Staphylococcus sp. triggers the inflammation in acne Moringa leaves are known to have potential antibacterial activity against acne-causing bacteria, such as Staphylococcus aureus. The aim of this research is to develop and evaluate a hydrogel preparation containing ethanol extract of Moringa oleifera L. leaves as an alternative treatment for acne. This research was carried out using an experimental method involving hydrogel formulation with varying concentrations of Moringa leaf extract of 4%, 7% and 10%. The evaluation carried out included organoleptic tests, homogeneity, pH, spreadability, adhesive power, physical stability, and antibacterial activity against Staphylococcus aureus. The research results showed that all hydrogel formulations met the specified quality standards, with appropriate pH, good spreadability and adhesion, and adequate physical stability. The antibacterial activity of the hydrogel also showed relatively strong effectiveness at extract concentrations of 4%, 7% and 10%. This research indicates that Moringa leaf extract hydrogel has the potential to be an effective topical preparation for the treatment of acne. Further research can be carried out by exploring the potential anti-inflammatory activity of the ethanol extract of Moringa oleifera leaves
GAMBARAN FAKTOR YANG BERHUBUNGAN DENGAN KEPATUHAN MINUM OBAT PADA PASIEN HIPERTENSI DALAM MENJALANKAN PENGOBATAN DI KLINIK DR NORMALA HASAN Werawati, Ayu; Sayyidah, Sayyidah; Hasan, Mochammad; Dewi, Bheta Sari; Aryanti, Fitriya Yuni
PHRASE (Pharmaceutical Science) Journal Vol 3, No 2 (2023): Pharmaceutical Science Journal Vol 3 No 2, 2023
Publisher : Sekolah Tinggi Ilmu Kesehatan Widya Dharma Husada Tangerang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52031/phrase.v3i2.612

Abstract

Hipertensi adalah hal penting yang biasa ditemui dalam masalah kesehatan masyarakat secara global. Diperkirakan bahwa hipertensi mempengaruhi sekitar 1 miliar orang di seluruh dunia, dan merupakan faktor risiko utama bagi penyakit kardiovaskular lainnya. Kepatuhan minum obat pada pasien hipertensi merupakan faktor penting dalam mengelola hipertensi secara efektif dan mencegah komplikasi terkait. Tujuan penelitian ini adalah untuk mengetahui faktor-faktor yang berhubungan dengan kepatuhan minum obat pada pasien hipertensi dalam menjalankan pengobatan di Klinik Dr Normala Hasan. Populasi dalam penelitian ini semua penderita hipertensi yang telah melakukan pengobatan pada bulan Mei 2020 berjumlah 50 orang. Jenis penelitian ini adalah penelitian deskriptif analitik kualitatif dan teknik sampling dengan cara accidental sampling, besar sampel menggunakan rumus Slovin didapatkan sebanyak 44 responden. Alat pengumpul data menggunakan kuesioner serta Analisis data menggunakan analisis univariat. Dari hasil penelitian diperoleh gambaran faktor-faktor yang berhubungan dengan kepatuhan minum obat pada pasien hipertensi dalam menjalankan pengobatan di klinik dr. Normala Hasan periode Mei 2020 adalah  29 responden (65,9%) dengan jenis kelamin Perempuan, karakteristik pendidikan terakhir responden yaitu 33 responden (75,0%) masuk kedalam kategori tinggi, karakteristik pekerjaan yaitu 37 responden (84,1%) tergolong dalam kategori bekerja, karakteristik lama menderita hipertensi yaitu 29 responden (65,9%) menderita hipertensi kurang dari 5 tahun, karakteristik keikutsertaan asuransi kesehatan yaitu 32 resonden (72,7%) menyatakan ikut serta/memiliki asuransi kesehatan, karakteristik pengetahuan tentang hipertensi yaitu 25 responden (56,8%) memiliki pengetahuan rendah tentang hipertensi, karakteristik dukungan keluarga yaitu 34 responden (77,7%) memiliki dukungan keluarga yang tinggi.
Standarisasi Ekstrak Etanol Daun Saga (Abrus precatorius L.) Sebagai Minuman Tradisional Bheta Sari Dewi; Beny Maulana Satria; Ayu Werawati; Sayyidah
Jurnal Sains Farmasi Dan Kesehatan Vol. 2 No. 1 (2024): Mei - Agustus
Publisher : CV. ITTC INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62379/jfkes.v2i1.964

Abstract

Saga has the species name Abrus precatorius L, which belongs to the Fabaceae family. The leaves of this plant are widely used by people as traditional medicine to reduce fever and cough. The aim of this research is to examine the use of saga leaf extract as a traditional drink that meets quality standards, so that the standardization process for this extract is carried out by determining specific parameters and non-specific parameters. The method used is maceration extraction using 70% ethanol. Specific parameters carried out include extract identity, organoleptic and phytochemical tests. Non-specific parameters used include ash content, acid soluble ash content, acid insoluble ash content, water content and drying shrinkage. The results obtained were a yield of 16.15% thick saga leaf extract, thick texture, greenish black in color, with a distinctive aroma. The extract contains saponin, alkaloid, tannin and flavonoid compounds. The results of non-specific parameter tests showed that the ash content was 2.17%, the acid soluble ash content was 2.17%, the acid insoluble ash content was <0.02%, the water content was 12.30% and the drying loss was 12.30%. The conclusion is that the research results meet extract quality standards. The data is expected to provide additional information regarding ethanol extract of saga leaves as a traditional medicine.
Riwayat Hipertensi dan Konsumsi Minuman Energi Berhubungan dengan Gagal Ginjal Susilo, Catur Budi; Dewi, Bheta Sari; Ramadhan, Afif; MS, Dewi Sartika; Kurrohman, Taufik
Jurnal Manajemen Kesehatan Yayasan RS.Dr. Soetomo Vol 9, No 1 (2023): JMK Yayasan RS.Dr.Soetomo, Pertama 2023
Publisher : STIKES Yayasan RS.Dr.Soetomo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29241/jmk.v9i1.1403

Abstract

Tren prevalensi gagal ginjal kronik setiap tahun terus menunjukkan peningkatan. Ia disebabkan gaya hidup masyarakat yang tidak sehat. Perlu kajianfaktor gaya hidup yang berhubungan gagal ginjal kronik dari waktu ke waktu. Studi ini untuk menganalisis hubungan riwayat hipertensi dan konsumsi minuman energi dengan kejadian gagal ginjal kronik. Desain penelitian yang digunakan adalah studi cross sectional. Jumlah sampel dalam penelitian ini sebanyak 56 responden. Diambil menggunakan teknik purposive sampling. Instrumen yang digunakan adalah kuesioner. Analisis data menggunakan uji chi square. Penelitian ini memperoleh temuan variabel yang berhubungan dengan kejadian gagal ginjal kronik adalah riwayat hipertensi (p=0,026 dan OR=4,3), dan konsumsi minuman energi (p=0,039 dan OR=4,4).Peningkatan risiko kejadian gagal ginjal dipengaruhi oleh adanya riwayat hipertensi dan konsumsi minuman energi.
FORMULASI SEDIAAN OBAT KUMUR EKSTRAK DAUN JARAK PAGAR (Jatropa curcus L) DENGAN KOMBINASI PENAMBAH PERASAN JERUK NIPIS (Citrus aurantifolis) SEBAGAI OBAT KUMUR ALAMI sayyidah, sayyidah; Satria, Beny Maulana; Hasanah, Nur; Maelaningsih, Firdha Senja; Kristiyowati, Anis Dwi; dewi, Bheta sari; Rahajeng, Suny Koswara
PHRASE (Pharmaceutical Science) Journal Vol 4, No 2 (2024): Pharmaceutical Science Journal Vol 4 No 2
Publisher : Sekolah Tinggi Ilmu Kesehatan Widya Dharma Husada Tangerang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52031/phrase.v4i2.815

Abstract

*Corresponding Author SayyidahE-mail: sayyidah@wdh.ac.id Bad breath is a symptom of an unnoticed disorder or disease. However, sufferers have unpleasant bad breath that arises from the oral cavity. According to Regional Health Research (Riskesdes) in 2013 in the city of South Tangerang, dental and oral health problems increased from 2007 by 19.9% to 2014 by 34.2%, dental and oral problems in children aged 10-14 years were 20, 6%. Jatropha leaf extract can be formulated as a natural mouthwash. Mouthwash is one of the mouth preparations widely available on the market which can be used to treat bad breath, one of the causes of bad breath is the bacteria Candida albicans. Jatropha curcus (Jatropha curcus L) leaves are able to inhibit Candida albicans bacteria that cause bad breath. Lime also contains flavonoids which play a very important role in inhibiting bacterial growth. The aim of this research is to obtain the best physical preparation formula and to determine the evaluation of a mouthwash made from jatropha leaf extract (Jatropa curcus L) with a combination of lime juice (citus aurantifolia) as a natural mouthwash. The formulation of this preparation is made with variations of lime juice in FI (5%), FII (10%), and FIII (15%). The formulation of jatropha leaf extract mouthwash (Jatropha curcus L) was evaluated by physical tests including organoleptic, pH, clarity and viscosity tests. Jatropha curcus (Jatropha curcus L) mouthwash preparation meets pH, viscosity and organoleptic requirements. From the results of the research I conducted, the best preparation was FIII which had a glycerin concentration (15%) and then had a pH value at week 0: 5.91, week 1: 5.07, week 2: 5 .05 and has a viscosity value of 6.90 Cp, which means this viscosity meets the requirements, while the claritytest results obtained did not produce a clear formulation because the color of the Jatropha leafextract is dark green, so it affects the clarity of the formulation.
FORMULASI DAN EVALUASI AKTIVITAS ANTIOKSIDAN SABUN CAIR BERBAHAN DASAR EKSTRAK DAUN KEMANGI DAN MADU Dewi, Bheta Sari; Utami, Sheila Meitania; Werawati, Ayu; Bachtiar, Wahyu; Dewantoro, Agung
PHRASE (Pharmaceutical Science) Journal Vol 4, No 2 (2024): Pharmaceutical Science Journal Vol 4 No 2
Publisher : Sekolah Tinggi Ilmu Kesehatan Widya Dharma Husada Tangerang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52031/phrase.v4i2.903

Abstract

Basil leaves  (Ocimum sanctum L.) and honey contain flavonoids and polyphenol compounds such as methyl eugenol, which are known to have antioxidant activity. Liquid soap is a form of pharmaceutical product that is often used to cleanse the body and provide additional protection to the skin. Objective: The aim of this study was to obtain the best physical formulation of a liquid soap combination of basil leaf extract and honey and its antioxidant activity. Method: Liquid soap preparations were made by adding basil leaf extract with various concentrations of 2g (FI), 4g (FII) and 8g (FIII) and honey, namely 5g (FI), 5g (FII) and 5g (FIII). Evaluation of liquid soap preparations included organoleptic, pH, and homogenity, as well as antioxidant activity test using the DPPH (1,1-diphenyl-2-picrylhydrazyl) method with a wavelength of 516 nm. Results: The results showed that Formula III (FIII) had the best results, namely organoleptic milk chocolate color, pH preparation (9.71-9.89), homogeneous preparation, stable preparation in storage for 12 days and showed the best IC50 value of 118.39 ppm. Conclusion: In conclusion, the combination of basil leaf extract and honey can be formulated as a liquid soap preparation with a concentration of 8g basil leaf extract and 5g honey in formula III (FIII) showing the effectiveness as the best formulation.