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All Journal Jurnal Ilmu Kefarmasian Indonesia Edu Masda Journal Jurnal Farmasi dan Sains Indonesia (JFSI) KOLONI Pharmaceutical Science Journal Jurnal Sains Farmasi dan Kesehatan
Ayu Werawati
STIKes Widya Dharma Husada Tangerang
Biochemistry, Genetics & Molecular Biology Chemistry Civil Engineering, Building, Construction & Architecture Health Professions Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences Veterinary Other

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LITERATURE REVIEW : EVALUASI PELAYANAN INFORMASI OBAT DI INSTALASI FARMASI Ayu Werawati; Sayyidah Sayyidah; Gina Aulia; Fatwa Hikmatul Kurnia
Edu Masda Journal Vol 6, No 1 (2022): Edu Masda Journal Volume 6 Nomor 1
Publisher : STIKes Kharisma Persada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52118/edumasda.v6i1.145

Abstract

Quality is something that greatly affects customer satisfaction. Quality is the level of excellence of something, both goods and services. The level of consumersatisfaction can be measured from the comparison between consumer expectations with the reality felt by the consumer against an item or service. In health services, to be able to provide a quality health service, it must be started from the fulfillment of high ethical standards. Nowadays where there has been a shift in the orientation of pharmaceutical service management which prioritizes improving the quality of life of patients (patient oriented) rather than just selling drugs to patients (drug oriented), it is necessary for pharmacists to have an active role in carrying out their competencies so that drug use can be more optimal. It is also necessary to reduce drug-related problems. The lack of drug information provided can lead to a lack of patient understanding of the drug and can have a negative impact on the patient. The objective of this study was to identify the evaluation of drug information services against pharmaceutical service standards and drug information service guidelines. This research method is a literature review. The inclusion criteria used were Indonesian research with drug information services in pharmacy installations, articles published 2011-2021, full text articles. The result is that the evaluation of drug information services has met pharmaceutical service standards and meets drug information service guidelines.  ABSTRAKKualitas merupakan hal yang sangat mempengaruhi kepuasan konsumen. Kualitas merupakan tingkat keunggulan sesuatu, baik barang ataupun jasa, sehingga tingkat kepuasan konsumen dapat diukur dari perbandingan antara harapan dengan kenyatan yang didapat terhadap suatu barang atau jasa. Pada pelayanan kesehatan, untuk dapat memberikan suatu pelayanan kesehatan yang berkualitas harus dimulai dari pemenuhan standar etika yang tinggi. Di masa sekarang ini dimana telah terjadi pergeseran orientasi manajemen pelayanan kefarmasian yang mengutamakan peningkatan kualitas hidup pasien (patient oriented)  daripada sekedar memasarkan obat kepada pasien (drug oriented) menyebabkan perlunya peran aktif Apoteker untuk menjalankan kompetensi nya agar penggunaan obat dapat lebih optimal. Hal ini juga diperlukan untuk mengurangi masalah terkait obat. Kurangnya informasi obat yang diberikan dapat menyebabkan kurangnya pemahanan pasien akan obat dan dapat berdampak buruk pada pasien.  Penelitian ini bertujuan untuk mengidentifikasi evaluasi pelayanan informasi obat terhadap standar pelayanan kefarmasian dan pedoman  pelayanan informasi obat. Metode penelitian ini merupakan suatu Literature review. Kriteria inklusi yang digunakan adalah penelitian Indonesia dengan pelayanan informasi obat di instalasi farmasi, artikel diterbitkan 2011-2021, artikel full text. Hasil penelitian yang dihasilkan bahwa evaluasi pelayanan informasi obat  sudah memenuhi standar pelayanan kefarmasian dan  memenuhi pedoman  pelayanan informasi obat.
Pengaruh Crude Fukoidan dari Ekstrak Sargassum crassifolium terhadap Kadar ICAM-1 dan VCAM-1 pada Sel Raw 264.7 yang Diinduksi Lipopolisakarida Ayu Werawati; Esti Mumpuni; Kusmardi Kusmardi; Dian Ratih Laksmitawati; Syamsudin Abdillah
JURNAL ILMU KEFARMASIAN INDONESIA Vol 17 No 1 (2019): JIFI
Publisher : Fakultas Farmasi Universitas Pancasila

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (805.613 KB) | DOI: 10.35814/jifi.v17i1.704

Abstract

Inflammation is the response of vascular tissue to infection and damaged tissue to remove agents that cause inflammation. Macrophages are the dominant cells in the inflammatory reaction. Adhesion of leukocytes to vascular endothelium is a main feature of the inflammatory process. The presence of adhesion molecules, such as ICAM-1 and VCAM-1, can lead to adhesion of monocytes and lymphocytes to endothelial cells via bonding adhesion molecules to endothelial cells. Crude fukoidan derived from Sargassum crassifolium taken from Garut waters and extracted with dilute HCl, tested for anti-inflammatory activity through inhibition of ICAM-1 and VCAM-1 using lipopolysaccharide-induced RAW 264.7 cell models. The viability test was carried out in the concentration range of 0.49-1000 µg / mL. The pattern of inhibition of cell proliferation is influenced by concentration. The highest concentration that caused cell viability of 80% was the concentration of 86.46μg / ml. Crude fukoidan reduced ICAM-1 and VCAM-1 levels at concentrations of 50 and 25 μg / ml.. Percent inhibition of ICAM-1 at 50 µg / mL concentration was 61.04% compared to control and 74.26% at 25 µg / mL concentration. While the percent inhibition of VCAM-1 a
FORMULASI DAN EVALUASI FISIK SEDIAAN SERUM ANTI-AGING YANG MENGANDUNG EKSTRAK TANAMAN DARI BERBAGAI LITERATUR Bheta Sari Dewi; Ayu Werawati
KOLONI Vol. 1 No. 4 (2022): DESEMBER 2022
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/koloni.v1i4.426

Abstract

Currently, beauty products are developing very fast, especially anti-aging facial care products. One of the most popular products is serum. Serum contains many concentrates that are useful for nourishing and moisturizing the skin. Several plants that have been studied have the potential to be used as serum preparations, namely apuh-apuhan leaves, brown rice, Malacca fruit, gotu kola, jamblang leaves, cempedak leaves, black pepper, and Perilla Frutescens. This study aims to determine the formulation and physical evaluation of serum preparations containing plant extracts in terms of various literatures. The method used is descriptive literature review by collecting various sources from several national journals. The number of national journals used is 7 and 1 international journal. The results of a literature study on serum formulations containing plant extracts can be formulated into serum dosage forms. Evaluation of serum preparations includes organoleptic tests, pH tests, spreadability tests, and viscosity tests. The results of the study concluded that the formulation with the most complete physical evaluation and had good stability without any signs of damage to the dosage form in the serum formulation with a pH value of 5.5, a spreadability of 6.63 cm and a viscosity value of 2900 cP were found in formulations containing the extract. malacca fruit plants. Keywords: anti-aging, serum, formulation, evaluation, extract
REVIEW: ANALISIS BETA-BLOCKERS MENGGUNAKAN METODE ELEKTROKIMIA Firdha Senja Maelaningsih; Diah Permata Sari; Ayu Werawati
PHRASE (Pharmaceutical Science) Journal Vol 1, No 1 (2021)
Publisher : Sekolah Tinggi Ilmu Kesehatan Widya Dharma Husada Tangerang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52031/phrase.v1i1.149

Abstract

Penggunaan obat golongan β-blockers sangat diatur di seluruh dunia karena sering disalahgunakan oleh para atlet untuk doping. Para atlet menggunakannya untuk meningkatkan performa karena dinilai dapat memiliki efek menurunkan denyut jantung dan mengurangi tremor. Selain itu, obat golongan β-blockers merupakan salah satu obat kardiovaskular yang paling banyak diresepkan. Analisis obat β-blockers dapat menggunakan beberapa metode. Metode yang paling sering digunakan untuk analisis obat golongan β-blockers adalah Kromatografi Cair Kinerja Tinggi (KCKT) dengan detektor Ultra Violet (UV) atau Mass Spectrometry (MS). Namun, KCKT merupakan metode yang kompleks, mahal, dan sulit. Selain itu, dalam penyiapan sampel diperlukan proses derivatisasi serta memerlukan waktu analisis yang lama. Metode lain yang dapat digunakan untuk analisis obat golongan β-blockers adalah metode elektrokimia. Metode elektrokimia merupakan suatu metode analisis obat yang penting karena sensitif, selektif, murah, serta dalam penyiapan sampel hanya melarutkan zat dalam perlarut yang tepat. Metode elektrokimia untuk analisis obat golongan β-blockers pada artikel ini terdiri dari tiga metode yaitu potensiometri, voltametri, dan amperometri
LITERATURE REVIEW ANALISIS HUBUNGAN KEPATUHAN PENGGUNAAN OBAT ANTIASMA DENGAN KUALITAS HIDUP PASIEN ASMA sayyidah sayyidah; Ayu Werawati; Firdha Senja Maelaningsih; Anis Dwi Kristiyowati
PHRASE (Pharmaceutical Science) Journal Vol 3, No 1 (2023): Pharmaceutical Science Journal Vol 3 No 1, 2023
Publisher : Sekolah Tinggi Ilmu Kesehatan Widya Dharma Husada Tangerang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52031/phrase.v3i1.471

Abstract

Asthma is a chronic inflammatory disease that causes blockage of the respiratory tract which is characterized by wheezing, coughing and a feeling of tightness in the chest that occurs repeatedly, especially at night or in the early morning. The purpose of this study was to identify the characteristics of drug use based on sex and smoking status and to identify the use of anti-acid drugs with the quality of life of asthma patients. The method used in this study uses a literature review research method by collecting various sources obtained from several research articles originating from Google Scholar both national journals. The number of articles used is 5 journals. Based on the results of a literature review that has been carried out, there is evidence of adherence to asthma medication and the quality of life of hige school patients grouped into high quality oflife by 60%, while 44,1%. With dherence to asthma patients, the higer adherence to asthma medication. Then the better qulity of life ppatients asthma.
STUDI LITERATUR KHASIAT KOMBINASI EKSTRA HERBA PEGAGAN DAN EKSTRAK DAUN LIDAH BUAYA SEBAGAI ANTIAGING Dewi, Bheta Sari; Werawati, Ayu
Edu Masda Journal Vol 7, No 1 (2023): Edu Masda Journal Volume 7 Nomor 1
Publisher : STIKes Kharisma Persada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52118/edumasda.v7i1.182

Abstract

Traditional herbs have been used for thousands of years for medicinal and skin care purposes. Several types of old ingredients are known for their anti-aging properties, such as Centella asiatica L herb extract and Aloe vera L leaf extract. Both are known for their beneficial properties in maintaining healthy and beautiful skin, including antioxidant, anti-inflammatory and regenerative effects. This study aims to evaluate the efficacy of a combination of gotu kola herb extract and aloe vera herb extract as an antiaging herb. Therefore, the two extracts need to look for related references. This research method involved studying the literature from articles and scientific journals related to the efficacy of  Centella asiatica L herb extract and aloe vera leaf extract as antiaging. The data were analyzed and compiled in the form of a literature synthesis. The results of this study indicate that the combination of gotu kola herb extract and aloe vera herb extract can have beneficial properties in antiaging skin care. The combination of these two herbs can help increase the production of collagen and elastin in the skin, which can help reduce signs of aging such as wrinkles and fine lines. Apart from that, both are also known for their properties which can help protect the skin from sun damage and other environmental factors. ABSTRAKHerbal tradisional telah digunakan sejak ribuan tahun yang lalu untuk tujuan pengobatan dan perawatan kulit. Beberapa jenis bahan lama terkenal dengan khasiat antiagingnya, seperti ekstrak herba pegagan (Centella asiatica L) dan ekstrak daun lidah buaya (Aloe vera L). Keduanya dikenal karena sifat-sifatnya yang bermanfaat dalam menjaga kesehatan dan kecantikan kulit, termasuk efek antioksidan, antiinflamasi, dan regeneratif. Penelitian ini bertujuan untuk mengevaluasi khasiat kombinasi ekstrak herba pegagan dan ekstrak herba lidah buaya sebagai antiaging . Oleh karena itu, kedua ekstrak tersebut perlu dicari referensi terkait. Metode penelitian ini melibatkan studi literatur dari artikel-artikel dan jurnal ilmiah terkait dengan khasiat ekstrak herba pegagan dan ekstrak daun lidah buaya sebagaiantiaging. Data dianalisis dan disusun dalam bentuk sintesis literatur. Hasil dari penelitian ini menunjukkan bahwa kombinasi ekstrak herba pegagan dan ekstrak daun lidah buaya dapat memiliki khasiat yang bermanfaat dalam perawatan kulit antiaging. Kombinasi kedua ekstrak ini dapat membantu meningkatkan produksi kolagen dan elastin dalam kulit, yang dapat membantu mengurangi tanda-tanda penuaan seperti keriput dan garis halus. Selain itu, keduanya juga dikenal karena sifat-sifatnya yang dapat membantu melindungi kulit dari kerusakan akibat sinar matahari dan faktor lingkungan lainnya.
Analisis Tingkat Pengetahuan Masyarakat Tentang Penggunaan Obat Analgetik NSAIDs di Desa Rawakalong Sayyidah, Sayyidah; Aulia, Gina; Fahriati, Andriyani Rahmah; Werawati, Ayu; Saputri, Laras Tri; Herdaningsih, Sulatri; Kristiyowati, Anis Dwi; Alexandre, Nahla Dany; Fitriani, Reka
Edu Masda Journal Vol 7, No 2 (2023): Edu Masda Journal Volume 7 Nomor 2
Publisher : STIKes Kharisma Persada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52118/edumasda.v7i2.192

Abstract

Pain is the main cause of patients coming to consult a doctor because the number of diseases related to pain reaches 80%. Pain is the main symptom of most medical conditions. Anesthetic drugs serve to reduce pain, mainly through their action on the central nervous system and change a person's response to pain. One of the drugs that are often used to treat inflammation are NSAIDs. The purpose of this study was to determine the level of public knowledge about the use of NSAID analgesic drugs in RT 003 and 004 in Rawakalong Village. The research was conducted using a descriptive research design, with a quantitative approach. Sampling used purposive sampling and the measuring instrument used was a questionnaire distributed to the community of RT 003 and 004 in Rawakalong Village. This study involved 111 respondents who had met the inclusion criteria. Based on the results of the study, it was found that the most age was 17-30 years as many as 51 respondents (46%), the most gender was male as many as 59 respondents (53%), the most education was high school as many as 80 respondents (72%), most occupations were employees as many as 34 respondents (31%), good level of knowledge of respondents as many as 64 respondents (58%), enough as many as 34 respondents (31%), less than 13 respondents (12%). The conclusion is that the level of public knowledge about the use of NSAID analgesic drugs in RT 003 and 004 in Rawakalong Village is 64 people (58%). AbstrakNyeri merupakan penyebab utama pasien datang berkonsultasi dengan dokter karena penyakit yang berhubungan dengan nyeri jumlahnya mencapai 80%. Obat anagetik berfungsi untuk mengurangi rasa nyeri, terutama lewat daya kerjanya atas sistem saraf sentral dan mengubah respons seseorang terhadap rasa sakit. Salah satu obat yang sering digunakan dalam mengatasi inflamasi adalah NSAIDs. Tujuan penelitian ini adalah untuk mengetahui tingkat pengetahuan masyarakat tentang penggunaan obat analgetik NSAID di RT 003 dan 004 Desa Rawakalong. Penelitian dilakukan dengan menggunakan rancangan penelitian deskriptif, dengan pendekatan kuantitatif. Pengambilan sampel menggunakan purposive sampling. Penelitian ini melibatkan 111 responden yang telah memenuhi kriteria inklusi. Berdasarkan hasil penelitian didapatkan bahwa umur terbanyak 17-30 tahun sebanyak 51 responden (46%), jenis kelamin terbanyak adalah laki-laki sebanyak 59 responden (53%), pendidikan terbanyak adalah SMA sebanyak 80 responden (72%), pekerjaan terbanyak adalah karyawan sebanyak 34 responden (31%), tingkat pengetahuan responden yang baik sebanyak 64 responden (58%), cukup sebanyak 34 responden (31%), kurang sebanyak 13 responden (12%). Kesimpulan tingkat pengetahuan masyarakat tentang penggunaan obat analgetik NSAID di RT 003 dan 004 Desa Rawakalong adalah berpengetahuan baik sebanyak 64 orang (58%).
FORMULASI DAN UJI AKTIVITAS ANTIBAKTERI SEDIAAN HIDROGEL EKSTRAK ETANOL DAUN KELOR Werawati, Ayu; Dewi, Bheta Sari; Hasanah, Uswatun; Aulia, Gina; Zahra, Annisa Fairuz
Edu Masda Journal Vol 8, No 2 (2024): EDU MASDA JOURNAL
Publisher : STIKes Kharisma Persada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52118/edumasda.v8i2.231

Abstract

Acne vulgaris is an inflammatory skin disease that is widespread in 85% of the human population. This disease occurs when hair follicles are blocked by dead skin cells. In some cases, bacteria such as Staphylococcus sp. triggers the inflammation in acne Moringa leaves are known to have potential antibacterial activity against acne-causing bacteria, such as Staphylococcus aureus. The aim of this research is to develop and evaluate a hydrogel preparation containing ethanol extract of Moringa oleifera L. leaves as an alternative treatment for acne. This research was carried out using an experimental method involving hydrogel formulation with varying concentrations of Moringa leaf extract of 4%, 7% and 10%. The evaluation carried out included organoleptic tests, homogeneity, pH, spreadability, adhesive power, physical stability, and antibacterial activity against Staphylococcus aureus. The research results showed that all hydrogel formulations met the specified quality standards, with appropriate pH, good spreadability and adhesion, and adequate physical stability. The antibacterial activity of the hydrogel also showed relatively strong effectiveness at extract concentrations of 4%, 7% and 10%. This research indicates that Moringa leaf extract hydrogel has the potential to be an effective topical preparation for the treatment of acne. Further research can be carried out by exploring the potential anti-inflammatory activity of the ethanol extract of Moringa oleifera leaves
GAMBARAN FAKTOR YANG BERHUBUNGAN DENGAN KEPATUHAN MINUM OBAT PADA PASIEN HIPERTENSI DALAM MENJALANKAN PENGOBATAN DI KLINIK DR NORMALA HASAN Werawati, Ayu; Sayyidah, Sayyidah; Hasan, Mochammad; Dewi, Bheta Sari; Aryanti, Fitriya Yuni
PHRASE (Pharmaceutical Science) Journal Vol 3, No 2 (2023): Pharmaceutical Science Journal Vol 3 No 2, 2023
Publisher : Sekolah Tinggi Ilmu Kesehatan Widya Dharma Husada Tangerang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52031/phrase.v3i2.612

Abstract

Hipertensi adalah hal penting yang biasa ditemui dalam masalah kesehatan masyarakat secara global. Diperkirakan bahwa hipertensi mempengaruhi sekitar 1 miliar orang di seluruh dunia, dan merupakan faktor risiko utama bagi penyakit kardiovaskular lainnya. Kepatuhan minum obat pada pasien hipertensi merupakan faktor penting dalam mengelola hipertensi secara efektif dan mencegah komplikasi terkait. Tujuan penelitian ini adalah untuk mengetahui faktor-faktor yang berhubungan dengan kepatuhan minum obat pada pasien hipertensi dalam menjalankan pengobatan di Klinik Dr Normala Hasan. Populasi dalam penelitian ini semua penderita hipertensi yang telah melakukan pengobatan pada bulan Mei 2020 berjumlah 50 orang. Jenis penelitian ini adalah penelitian deskriptif analitik kualitatif dan teknik sampling dengan cara accidental sampling, besar sampel menggunakan rumus Slovin didapatkan sebanyak 44 responden. Alat pengumpul data menggunakan kuesioner serta Analisis data menggunakan analisis univariat. Dari hasil penelitian diperoleh gambaran faktor-faktor yang berhubungan dengan kepatuhan minum obat pada pasien hipertensi dalam menjalankan pengobatan di klinik dr. Normala Hasan periode Mei 2020 adalah  29 responden (65,9%) dengan jenis kelamin Perempuan, karakteristik pendidikan terakhir responden yaitu 33 responden (75,0%) masuk kedalam kategori tinggi, karakteristik pekerjaan yaitu 37 responden (84,1%) tergolong dalam kategori bekerja, karakteristik lama menderita hipertensi yaitu 29 responden (65,9%) menderita hipertensi kurang dari 5 tahun, karakteristik keikutsertaan asuransi kesehatan yaitu 32 resonden (72,7%) menyatakan ikut serta/memiliki asuransi kesehatan, karakteristik pengetahuan tentang hipertensi yaitu 25 responden (56,8%) memiliki pengetahuan rendah tentang hipertensi, karakteristik dukungan keluarga yaitu 34 responden (77,7%) memiliki dukungan keluarga yang tinggi.
Standarisasi Ekstrak Etanol Daun Saga (Abrus precatorius L.) Sebagai Minuman Tradisional Bheta Sari Dewi; Beny Maulana Satria; Ayu Werawati; Sayyidah
Jurnal Sains Farmasi Dan Kesehatan Vol. 2 No. 1 (2024): Mei - Agustus
Publisher : CV. ITTC INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62379/jfkes.v2i1.964

Abstract

Saga has the species name Abrus precatorius L, which belongs to the Fabaceae family. The leaves of this plant are widely used by people as traditional medicine to reduce fever and cough. The aim of this research is to examine the use of saga leaf extract as a traditional drink that meets quality standards, so that the standardization process for this extract is carried out by determining specific parameters and non-specific parameters. The method used is maceration extraction using 70% ethanol. Specific parameters carried out include extract identity, organoleptic and phytochemical tests. Non-specific parameters used include ash content, acid soluble ash content, acid insoluble ash content, water content and drying shrinkage. The results obtained were a yield of 16.15% thick saga leaf extract, thick texture, greenish black in color, with a distinctive aroma. The extract contains saponin, alkaloid, tannin and flavonoid compounds. The results of non-specific parameter tests showed that the ash content was 2.17%, the acid soluble ash content was 2.17%, the acid insoluble ash content was <0.02%, the water content was 12.30% and the drying loss was 12.30%. The conclusion is that the research results meet extract quality standards. The data is expected to provide additional information regarding ethanol extract of saga leaves as a traditional medicine.
Co-Authors Agung Dewantoro Alexandre, Nahla Dany Andriyani Rahmah Fahriati Anis Dwi Kristiyowati Aryanti, Fitriya Yuni Aulia, Gina Azzahra, Aristi Bachtiar, Wahyu Beny Maulana Satria Bheta Sari Dewi Diah Permata Sari Dian Ratih Laksmitawati Esti Mumpuni Fatwa Hikmatul Kurnia Firdha Senja Maelaningsih Fitriani, Reka Gina Aulia Herdaningsih, Sulatri Kristiyowati, Anis Dwi Kurniawati, Dewi Indah Kusmardi Kusmardi Mochammad Hasan, Mochammad Neneng Sri Purwaningsih Nur Hasanah Nurwulan Adi Ismaya Putri, Annisa Septyana Saputra, Aldi Saputri, Laras Tri Sayyidah Sayyidah Sayyidah Sayyidah Sayyidah Sayyidah, Sayyidah Sheila Meitania Utami Syamsudin Abdillah Uswatun Hasanah Zahra, Annisa Fairuz