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Evaluation of Prescription and Non-Prescription Services in Pharmaceutical Facilities: A Patient Simulation Study in the Lamongan Region: Evaluasi Pelayanan Resep dan Non Resep di Fasilitas Kefarmasian: Studi Simulasi Pasien di Wilayah Lamongan Cici Sayyidatul Adhimi; Primanitha Ria Utami; Enggar Ayu Fifianti; Erika Cindiana Pramudia Putri; Heru Setiawan; Lailya Eka; Muhammad Hadi Ma'ruf
Journal Pharmasci (Journal of Pharmacy and Science) Vol. 8 No. 2 (2023): Journal Pharmasci (Journal of Pharmacy and Science)
Publisher : Akademi Farmasi Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53342/pharmasci.v8i2.342

Pharmaceutical Services is an activity in identifying, preventing and resolving drug problems related to health. A new paradigm that is currently (patient oriented) with the aim of improving the quality of life of patients with an understanding of a drug or drug prescription from a doctor. This study aims to describe the implementation of prescription and non-prescription services based on Pharmaceutical Service Standards by pharmacists and pharmacists in the Lamongan area. This research is a descriptive research conducted by observation using patient simulation techniques. The location in the Lamongan area. The time of the study was November - December 2022. The sample consisted of 34 pharmacists who provide self-medication services at the Lamongan pharmaceutical facility, which were using the simple random sampling technique. The instruments used for data collection were scenarios of self-medication patients (for cases of fever, cough, runny nose), observation sheets, standard checklists for pharmaceutical services. The results of the study indicate that prescription and non-prescription services carried out by pharmacists in Lamongan have not fully complied with regulatory standards regarding pharmaceutical services. A total of 70.23% met pharmaceutical service standards. Special attention is needed in developing pharmaceutical competence, especially in providing effective patient education.

The Correlation Between Potential Antidiabetic Side Effects And Risk Factors In Type 2 Diabetes Mellitus Patients at Hospital Lamongan: Hubungan Kejadian Efek Samping Potensial Antidiabetes Dengan Faktor Risiko Pasien Diabetes Melitus Tipe 2 Di RS Lamongan Enggar Ayu Fifianti; Primanitha Ria Utami; Anisa Zulfa Fatihah
Journal Pharmasci (Journal of Pharmacy and Science) Vol. 10 No. 1 (2025): Journal Pharmasci (Journal of Pharmacy and Science)
Publisher : Akademi Farmasi Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53342/pharmasci.v10i1.464

Diabetes mellitus is a metabolic disease caused by abnormalities in insulin performance and/or insulin secretion. Risk factors for side effects of drugs need to consider aspects of age, gender, and body mass index. This study aims to determine the relationship between potential side effects of antidiabetics and risk factors for type 2 diabetes mellitus. This study was conducted at Lamongan Hospital during the period January-March 2024. The study design used a cross-sectional design with data collection from patient medical records and the results of interviews filling out the naranjo questionnaire. The population in this study was 95 patients. The sample was selected using a purposive sampling technique and 89 patients met the inclusion criteria. Based on the results of the study, the most common potential side effect of antidiabetes was hypoglycemia experienced by 25 patients (28.08%) with the dominant number of hypoglycemia side effects due to the use of insulin actrapid (11.23%). The naranjo score results showed probable (89.89%) which means that the possibility of complaints in the form of hypoglycemia in patients is a side effect of antidiabetes. Hypoglycemia is characterized by a decrease in blood glucose levels <70 mg/dl (<4.0 mmol/L). Signs of hypoglycemia that appear in patients are trembling, hunger, nausea, and dizziness. Data analysis using the Spearman Rank Correlation test showed a significant relationship between the occurrence of potential side effects of Antidiabetics with age risk factors (p=0.004) and did not have a significant relationship with gender risk factors (p=0.553) and body mass index (p=0.473). The presence of age factors due to changes in physiology and body biochemistry, is closely related to increased glucose intolerance which is at risk of insulin resistance. Education of health workers, especially from Pharmacists, determines the success of therapy and prevention of drug-related problems including drug side effects.

The Relationship Of Polypharmacy With Glomerular Filtration Rate In Patients With Chronic Kidney Failure: Hubungan Polifarmasi dengan Laju Filtrasi Glomerulus pada Pasien Gagal Ginjal Kronik Erika Cindiana Pramudia Putri; Primanitha Ria Utami; Irma Susanti
Journal Pharmasci (Journal of Pharmacy and Science) Vol. 10 No. 2 (2025): Journal Pharmasci (Journal of Pharmacy and Science)
Publisher : Akademi Farmasi Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53342/pharmasci.v10i2.488

Polypharmacy is generally used in hemodialysis patients with an average number of drugs given being 14 drugs. In addition to detecting and preventing the severity of renal function, hemodialysis can increase the glomerular filtration rate. This study aims to determine the relationship between polypharmacy and glomerular filtration rate in patients with chronic renal failure at RSUD Dr. Soegiri Lamongan. The research design uses design descriptive with method retrospective with data collection sheet instruments, the population in this study was 174 patients, the sample was selected using techniques purposive sampling By determining the inclusion criteria, 121 patients were obtained. Data analysis using tests Spearman Rho. The results of the number of drug use in chronic kidney failure patients showed that there were more major polypharmacy incidents of ?6 drugs, as many as 115 patients (95.04%). The glomerular filtration rate in patients is mostly in the range <15 ml/minute/1,73 m2 as many as 120 patients (99.17%). The results of data analysis show that there is no relationship between polypharmacy and glomerular filtration rate p 0.820. In theory, polypharmacy is related to a decrease in glomerular filtration rate, worsening the patient's condition, resulting in undesirable side effects and drug interactions. Polypharmacy with glomerular filtration rate will result in renal dysfunction and can further exacerbate multimorbidity, so that high levels of comorbidities and chronic inflammation can lead to worse clinical consequences.

The Effect of Risk Factors for Coronary Heart Disease on Transaminase Levels: Pengaruh Faktor Risiko Penyakit Jantung Koroner Terhadap Kadar Transaminase Narda Eka Rohmah Safitri; Primanitha Ria Utami; Riana Prastiwi Handayani
Journal Pharmasci (Journal of Pharmacy and Science) Vol. 10 No. 1 (2025): Journal Pharmasci (Journal of Pharmacy and Science)
Publisher : Akademi Farmasi Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53342/pharmasci.v10i1.489

Coronary heart disease (CHD) is caused by blood vessel blockage due to fat accumulation. Risk factors for CHD include age, gender, comorbidities, and BMI. An increase in high lipid levels in the body is an important factor in the pathophysiology of CHD. Additionally, elevated lipid levels can lead to fat accumulation in the liver, thereby increasing transaminase levels. Elevated transaminase levels can indicate heart disorders. This study aims to examine the influence of CHD risk factors on transaminase levels at Dr. Soegiri Hospital, Lamongan. This research uses cross-sectional design with descriptive analysis. Data were collected prospectively. The analysis conducted using Spearman's Rank Correlation Test. Out of 104 patients studied, 96 patients met the inclusion criteria. The analysis results showed P-value <0.05 for the risk factors of gender (P=0.00), age (P=0.00), and BMI (P=0.00) in relation to transaminase levels. These results indicate significant influence of the risk factors gender, age, and BMI on transaminase levels. In advanced age, organ function declines, affecting transaminase levels. Gender differences affect transaminase levels due to hormonal differences and liver enzyme activity, and in patients with high BMI, there is metabolic imbalance of fats, leading to fat accumulation in adipose tissues, which affects transaminase levels.

A Comparison of the Medication Adherence of Hypertension Patients Using the Medication Possession Ratio and Pill Count Methods at the Kembangbahu Health Center: Perbandingan Kepatuhan Minum Obat Pasien Hipertensi dengan Menggunakan Metode MPR (Medication Possesion Rasio) dan Pill Count di Puskesmas Kembangbahu Ariska Qurrotul Aini; Irma Susanti; Primanitha Ria Utami
Journal Pharmasci (Journal of Pharmacy and Science) Vol. 11 No. 1 (2026): Journal Pharmasci (Journal of Pharmacy and Science)
Publisher : Akademi Farmasi Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53342/pharmasci.v11i1.491

Pasien hipertensi diharuskan mengonsumsi obat setiap hari yang menyebabkan banyaknya pasien tidak mematuhi proses pengobatan sesuai yang telah dianjurkan. Kepatuhan yang rendah dapat menyebabkan risiko penyakit lain serta memperburuk keadaan pasien sehingga menyebabkan kegagalan terapi dalam proses penyembuhan. Penelitian ini bertujuan untuk mengetahui perbandingan kepatuhan minum obat pasien hipertensi dengan menggunakan metode MPR (Medication Possession Ratio) dan Pill Count. Desain penelitian yang digunakan adalah deskriptif dilakukan dengan pendekatan cross sectional. Pengumpulan data dilakukan secara prospektif dengan teknik sampling purposive sampling. Hasil penelitian yang diperoleh sebanyak 150 sampel yang telah memenuhi kriteria inklusi untuk metode MPR dan pill count. Hasil penelitian kepatuhan minum obat menunjukkan bahwa menggunakan metode Pill count memiliki jumlah pasien yang patuh lebih banyak yaitu 135 pasien (90,0%) dibandingkan dengan metode MPR yaitu 117 pasien (78,0%). Hasil uji perbandingan metode MPR dengan Pill count disimpulkan bahwa nilai p = 0,002 maka terdapat perbedaan yang signifikan antara metode MPR dan metode Pill count terhadap kepatuhan minum obat pasien hipertensi. Banyaknya ketidakpatuhan pada metode MPR ini terdapat perbedaan pada kepatuhan metode Pill count, hal ini disebabkan pasien yang tidak patuh menebus ulang resep atau melakukan kontrol kembali ke fasilitas pelayanan kesehatan pasien masih dapat mengonsumsi obat dengan mendapatkan obat di fasilitas pelayanan kefarmasian lainnya.

The Relationship Of The Medication Compliance With The Quality Of Life Of Type 2 Diabetes Mellitus Patients With Gangrene Complications: Hubungan Tingkat Kepatuhan Minum Obat terhadap Kualitas Hidup Pasien Diabetes Mellitus Tipe 2 dengan Komplikasi Gangren Wulan Dwi Jumadi; Primanitha Ria Utami; Irma Susanti
Journal Pharmasci (Journal of Pharmacy and Science) Vol. 11 No. 1 (2026): Journal Pharmasci (Journal of Pharmacy and Science)
Publisher : Akademi Farmasi Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53342/pharmasci.v11i1.495

Diabetes Mellitus (DM) type 2 is a serious and chronic disease characterized by high blood glucose levels. DM causes complications such as gangrene. The success of DM management is influenced by factors, patient compliance in taking medication, which can ultimately reduce morbidity and mortality and improve the patient's quality of life. This study aims to identify the relationship between medication adherence and the quality of life of type 2 DM patients with gangrene complications. Sampling was carried out using purposive sampling and there were 95 type 2 DM patients with gangrene at the Sahabat Sehat Karanggeneng Clinic. Respondents with type 2 diabetes mellitus had high compliance with taking medication, reaching 93% and the lowest compliance with taking medication, reaching 7%. Respondents with type 2 diabetes mellitus had a moderate quality of life, namely 10.52%, good 62.01% and very good, namely 27.47%. This research uses a non-experimental cross-sectional study method. Spearman-rank test was used to analyze the data. The research instrument used the MARS-10 questionnaire for medication adherence and Whoqol-Bref for quality of life. The results of the Spearman-rank p-value test were p=0.001. There is a significant relationship between adherence to taking medication and the quality of life of type 2 DM patients with gangrene complications. Effective management of type 2 DM and prevention of gangrene complications are very important to improve compliance and maintain patient quality of life.

The Relationship Between Level Knowledge And Duration Of Diabetes Mellitus Type II And The Incidence Of Diabetic Ulcers At The Sahabat Sehat Clinic: Hubungan Tingkat Pengetahuan Dan Lama Menderita Diabetes Melitus Tipe II Dengan Kejadian Ulkus Diabetikum Di Klinik Sahabat Sehat Filza Eka Nur Sholeh; Primanitha Ria Utami; Sri Bintang Sahara
Journal Pharmasci (Journal of Pharmacy and Science) Vol. 10 No. 2 (2025): Journal Pharmasci (Journal of Pharmacy and Science)
Publisher : Akademi Farmasi Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53342/pharmasci.v10i2.519

Hyperglycemia caused by decreased insulin production or the ability to secrete it is a sign of DM. The disease diabetes mellitus is not communicable (NCDs) that causes the most deaths. Complications of diabetic ulcers can occur due to poor treatment and high blood sugar levels. The purpose of this study was to determine whether there is a relationship between the level of knowledge about diabetes mellitus (DM) and the number of diabetic ulcers at the Sahabat Sehat Clinic, Karanggeneng District. A total of 95 type 2 diabetes patients experienced diabetic ulcers, and this study used a descriptive method with a cross-sectional approach. Using the chi-square statistical test, the data were evaluated. The results showed that the level of knowledge was 0.017 and the duration of diabetes mellitus sufferers was 0.000. The degree of knowledge has a positive correlation with The length of diabetes and the degree of knowledge mellitus sufferers with the incidence of diabetic ulcers at the Sahabat Sehat clinic. Thus, the level of knowledge can reduce the risk of complications of diabetes mellitus, while patients with diabetes mellitus who do not have enough knowledge have a higher risk.

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