Article Per Year (5 Year)
p-Index From 2021 - 2026
0.408
P-Index
This Author published in this journals
All Journal Journal Pharmasci (Journal of Pharmacy and Science)
Lintang Bismantara
Universitas Kadiri
Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology

Published : 2 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search

 1 
Comparison of Vitamin C Levels in Roasted Green Coconut Water and Green Coconut Water (Cocos nucifera) Using the UV-Vis Spectrophotometry Method: Perbandingan Kadar Vitamin C pada Air Kelapa Hijau Bakar dan Air Kelapa Hijau (Cocos nucifera) menggunakan Metode Spektrofotometri UV-Vis Tridoso Sapto Agus Priyono; Lintang Bismantara; Carmia Dewi Salmaa
Journal Pharmasci (Journal of Pharmacy and Science) Vol. 11 No. 1 (2026): Journal Pharmasci (Journal of Pharmacy and Science)
Publisher : Akademi Farmasi Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53342/pharmasci.v11i1.539

Abstract

The coconut (Cocos nucifera) is a plant known as the Tree of Life. One of the chemicals found in coconut water is vitamin C, which functions as an antioxidant. Now, a new innovation has emerged: a method of serving coconut water by burning it. The benefits of coconut water include preventing angina, muscle aches, and cholesterol. This study aimed to compare the vitamin C levels produced by roasted green coconut water and green coconut water. The method used in this study was to roast green coconuts for four hours, then analyze the vitamin C content of the coconut water using UV-Vis spectrophotometry at a wavelength of 266 nm. The method used in this study is that green coconut is burned for four hours then the coconut water is analyzed for vitamin C content using UV-Vis Spectrophotometry with a wavelength of 266 nm. The results showed that there was a significant difference between grilled green coconut water and coconut water. The highest vitamin C concentration was found in roasted green coconut water with a value of 20,784 ± 0,34 ppm. While the content of green coconut water with a value of 7,359 ± 0,04 ppm. The conclusion of this study is that vitamin C in roasted green coconut water has higher levels than green coconut water.
The Effect of Stearic Acid Variation on the Physicochemical Profile of Coenzyme Q10 Nanostructured Lipid Carriers: Pengaruh Variasi Asam Stearat terhadap Profil Fisikokimia Nanostructured Lipid Carriers Koenzim Q10 Tri Doso Sapto Agus Priyono; Lintang Bismantara; Ninik Mas Ulfa; Dian Nurmawati
Journal Pharmasci (Journal of Pharmacy and Science) Vol. 11 No. 2 (2026): Journal Pharmasci (Journal of Pharmacy and Science)
Publisher : Akademi Farmasi Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53342/pharmasci.v11i2.603

Abstract

Coenzyme Q10 (CoQ10) possesses potent antioxidant activity; however, its therapeutic efficacy is limited by poor solubility, large particle size, and low bioavailability, which lead to poor bodily absorption and high susceptibility to environmental degradation. To address these limitations, Nanostructured Lipid Carriers (NLC) are utilized due to their ability to enhance solubility, stability, and bioavailability. Within this system, the concentration of solid lipids, such as stearic acid, plays a pivotal role; its long carbon chain forms an imperfect crystalline matrix that multiplies drug entrapment capacity, prevents drug expulsion during storage, and enhances topical penetration via a skin-occlusive effect. This study aims to investigate the effect of varying stearic acid concentrations on the particle size and physicochemical characteristics of CoQ10-loaded NLCs. The NLCs were prepared using the emulsification and high-shear homogenization method, followed by characterization encompassing organoleptic properties, homogeneity, pH, spreadability, particle size, and polydispersity index. The results demonstrated that increasing the stearic acid concentration significantly influenced both the physicochemical profile and particle size. The formula with the optimal stearic acid concentration yielded nanometer-scale particle sizes with a homogenous polydispersity index. In conclusion, variations in stearic acid concentration exert a significant effect on the physical characteristics of CoQ10 NLCs, and an appropriate concentration can produce a stable nano-delivery system for topical application.
Co-Authors Carmia Dewi Salmaa Dian Nurmawati Tri Doso Sapto Agus Priyono Tridoso Sapto Agus Priyono Ulfa, Ninik Mas