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All Journal Dentika Dental Journal E-Prodenta Journal of Dentistry
Milla, Lalita El
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Dentistry Health Professions Medicine & Pharmacology

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HYDROXYAPATITE, ALGINATE, AND CHITOSAN FOR BONE SCAFFOLDS: SPECTROSCOPY STUDY: HIDROKSIAPATIT, ALGINAT, DAN KITOSAN SEBAGAI BAHAN SCAFFOLD TULANG: STUDI SPEKTROSKOPI Milla, Lalita El
Dentika: Dental Journal Vol. 19 No. 2 (2016): Dentika Dental Journal
Publisher : TALENTA

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (423.048 KB) | DOI: 10.32734/dentika.v19i2.457

Abstract

Scaffolds is three dimensional structure that serves as a framework for bone growth. Natural materials are often used in synthesis of bone tissue engineering scaffolds with respect to compliance with the content of the human body. Among the materials used to make scafffold was hydroxyapatite, alginate and chitosan. Hydroxyapatite powder obtained by mixing phosphoric acid and calcium hydroxide, alginate powders extracted from brown algae and chitosan powder acetylated from crab. The purpose of this study was to examine the functional groups of hydroxyapatite, alginate and chitosan. The method used in this study was laboratory experimental using Fourier Transform Infrared (FTIR) spectroscopy for hydroxyapatite, alginate and chitosan powders. The results indicated the presence of functional groups PO43-, O-H and CO32- in hydroxyapatite. In alginate there were O-H, C=O, COOH and C-O-C functional groups, whereas in chitosan there were O-H, N-H, C=O, C-N, and C-O-C. It was concluded that the third material containing functional groups as found in humans that correspond to the scaffolds material in bone tissue engineering.
PERAN KASEIN SUSU KAMBING PERANAKAN ETAWA TERHADAP PENINGKATAN KEKERASAN ENAMEL GIGI SULUNG Sutanti, Viranda; Manzila, Nilta; Milla, Lalita El; Hartami, Edina
E-Prodenta Journal of Dentistry Vol 5, No 1 (2021)
Publisher : Fakultas Kedokteran Gigi UB

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.eprodenta.2021.005.01.3

Abstract

Latar Belakang: Demineralisasi merupakan suatu proses hilangnya mineral pada gigi. Proses demineralisasi tersebut mengakibatkan penurunan kekerasan enamel gigi sehingga dapat mengakibatkan terjadinya karies gigi. Susu kambing Peranakan Etawa terdiri dari kasein yang mengandung peptida bioaktif yang diyakini dapat meningkatkan kandungan mineral pada gigi dengan cara melepaskan ion kalsium dan fosfat. Tujuan: Mengetahui efektivitas kasein susu kambing PE dalam sediaan gel dalam meningkatkan kekerasan enamel gigi sulung secara In Vitro. Metode: Desain penelitian ini adalah true experimental pretest-postest control group design. Metode yang dilakukan adalah mengoles setiap permukaan fasial sampel gigi sulung dengan menggunakan bahan uji selama 3 menit, lalu sampel gigi sulung direndam menggunakan saliva buatan dalam inkubator selama 24 jam pada suhu 37°C selama 15 hari. Pengujian kekerasan enamel gigi sulung dilakukan menggunakan Micro Vickers Hardness Test. Hasil: Peningkatan nilai kekerasan enamel didapatkan sesudah perlakuan dengan nilai signifikansi 0,013 (p<0,05) pada uji One Way Anova. Semakin tinggi konsentrasi gel kasein susu kambing PE menunjukkan semakin tinggi nilai kekerasan enamel gigi sulung. Kesimpulan: Gel Kasein Susu Kambing PE terbukti efektif terhadap peningkatan kekerasan enamel gigi sulung.
Co-Authors Hartami, Edina Manzila, Nilta Sutanti, Viranda