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All Journal Dentika Dental Journal ODONTO Dental Journal Interdental Jurnal Kedokteran Gigi (IJKG) Jurnal Ilmiah Medicamento Jurnal Abdi Dharma Masyarakat Odonto dental journal
Mochammad Taha Ma’ruf
Bagian Bedah Mulut, Fakultas Kedokteran Gigi, Universitas Mahasaraswati Denpasar
Biochemistry, Genetics & Molecular Biology Dentistry Economics, Econometrics & Finance Health Professions Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Public Health

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RED GINGER RHIZOME EXTRACT GEL IMPROVES COLLAGEN DENSITY POST EXTRACTION OF GUINEA PIG TEETH Putu Dewi, Sulistiawati; Ma’ruf, Mochammad Taha
Interdental: Jurnal Kedokteran Gigi Vol 17 No 1 (2021): Interdental Jurnal Kedokteran Gigi (IJKG)
Publisher : Faculty of Dentistry, Mahasaraswati Denpasar University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46862/interdental.v17i1.1190

Abstract

Introduction: tooth extraction can cause injury involving the bone structure and soft tissue of the oral cavity. Tooth extraction can cause various complications, one of which is bleeding. Red ginger is a type of spice that ismost widely used in various food and beverage recipes. Red ginger is commonly used by the public as a cold, digestive, antipyretic, anti-inflammatory, and analgesic drug. Various studies have shown that ginger has antioxidant properties, flavonoids, and oleoresins found in the rhizome. The purpose of this study was to determine the effect of the concentration of red ginger extract (Zingiber Officinale Varr. Rubrum) on collagen density after extraction of guinea pig teeth (Cavia porcellus). Materials and method: the method of this research is an experimental in vivo laboratory with a post-test-only control group design. The hypothesis test was carried out by the One Way Anova test and was carried out on 24 male guinea pigs. The experimental animals were divided into 4 groups which were distinguished by concentration, 10%, 20%, 30%, and the control group was given 2% CMC-Na gel respectively. Results and discussions: The results showed that red ginger extract gel concentrations of 10%, 20%, and 30% can increase collagen density compared to CMC-Na 2%. Conclusion: the red ginger extract gel with a concentration of 30% was most effective at increasing collagen density compared to concentrations of 10% and 20%.
AKTIVITAS ANTIBAKTERI EKSTRAK BUAH MAHKOTA DEWA (Phaleria macrocarpa) TERHADAP Staphylococcus aureus Ma’ruf, Mochammad Taha; Setiawan, Setiawan; Putra, Bayu Prayoga Deta
Interdental: Jurnal Kedokteran Gigi Vol 13 No 2 (2017): Interdental Jurnal Kedokteran Gigi (IJKG)
Publisher : Faculty of Dentistry, Mahasaraswati Denpasar University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46862/interdental.v13i2.360

Abstract

Tooth extraction though always not cause problems, but can cause some complications, one of which is endocarditis infection. The infection is caused by Staphylococcus aureus that causes abnormalities of the heart valves. The use of herbal ingredients to be an alternative to antibacterial bacteria as a result of increased resistance to antibiotics. Mahkota Dewa fruit (Phaleria macrocarpa) was selected as an antibacterial because it is active substances contains such as alkaloids, saponins, flavonoids, and polyphenols. The purpose of this study was to determine the effective concentration of the extract Mahkota Dewa fruit as an antibacterial against Staphylococcus aureus that can be made of a product in the form of a gel that can be applied to a tooth extraction wound to prevent endocarditis infection. The study is in vitro an experimental laboratory approaches Post test Only Control Group Design. Samples are distinguished by the concentration differences of the Mahkota Dewa fruit extract are 60%, 70%, 80%, 90% and 100%. The results showed that the Mahkota Dewa fruit extract concentration of 70% effective as an antibacterial against Staphylococcus aureus. The effectiveness of the extract Phaleria influenced by the ability of the active substance content of flavonoids lysis of bacterial cells.
FIKSASI TULANG DENGAN ALAT BERBAHAN DASAR POLIMER (Uji Biokompatibilitas) Ma'ruf, Mochammad Taha
Interdental: Jurnal Kedokteran Gigi Vol 14 No 2 (2018): Interdental Jurnal Kedokteran Gigi (IJKG)
Publisher : Faculty of Dentistry, Mahasaraswati Denpasar University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46862/interdental.v14i2.371

Abstract

Bone fracture fixation device have been using rigid metallic materials such as titanium, titanium-alloy or cobalt chrome. Besides having some advantages, as the titanium fixation devices also have disadvantages. It is challenge to develop the use of polymeric materials have good biocompatibility and mechanical strength appropriate to have a bone fracture fixation devices that can be absorbed by the body, such as Polyvinyl Alcohol (PVA). The purpose of this study is to know whether the PVA-HA composite with catgut reinforced has good biocompatibility without toxicity and hypersensitivity effects in experimental animals. Biocompatibility testing include local cytotoxicity and type IV contact hypersensitivity test using wistar rats (Rattus norvegicus). Testing is done through two phases, induction or sensitization phase is by rubbing PVA-HA composite with catgut reinforced ointment puder on the ears. Local toxicity testing is done by implantation of PVA-HA composite with catgut reinforced on the back catgut wistar rats. The results showed no discoloration or induration on animal ears in all treatment and control groups on the sensitization and the elicitation phase. There were no significant differences of the thickness of the wistar rats ears from all treatment groups before and after treatment on measures 24, 48 and 72 hours (ρ >0.05). Microscopic examination showed no infiltration of acute inflammatory cells such as neutrophils, basophils or eusinofil and chronic inflammatory cell infiltration such as macrophages, lymphocytes and plasma cells. It can be concluded that the PVA-HA (60:40)composite with catgut reinforced is a material that does not cause toxicity and hypersensitivity in experimental animals, thus potentially be used as bone fractures fixation material.
EFEKTIVITAS MINYAK CENGKEH DAN PULPERYL® DALAM MENGHAMBAT AKUMULASI BAKTERI Streptococcus mutans SECARA IN VITRO Poernomo, Hendri; Ma'ruf, Mochammad Taha; Setiawan, Setiawan; Wati, PA Nindya Winda
Interdental: Jurnal Kedokteran Gigi Vol 14 No 2 (2018): Interdental Jurnal Kedokteran Gigi (IJKG)
Publisher : Faculty of Dentistry, Mahasaraswati Denpasar University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46862/interdental.v14i2.372

Abstract

One of the complications that can occur after tooth extraction is dry socket. Bacterial infection is one among the various causes of dry socket where Streptococcus mutans become one of the bacteria that have a role as a cause. Eugenol is the main active substancethat owned by clove oil with eugenol as antibacterial properties. The research pyupose was to determine the effectiveness of clove oil in inhibiting the accumulation of Streptococcus mutans bacteria in the dry socket. The research method used to see the inhibition of clove oil 5% also the negative control of ethanol to Streptococcus mutans bacteria in the form of clear zone using a vernier caliper. The research result shows that the clove oil 5% effective in inhibiting Streptococcus mutans, with the average inhibition zone of clove oil 5% was 15 mm. Statistical test result showed significant results (ANOVA test = 0.001 with ρ <0.05). The conclusion that can be obtained from this study was clove oil 5%may inhibit the accumulation of Streptococcus mutans bacteria in the dry socket.
PENGARUH GEL EKSTRAK BAWANG PUTIH (ALLIUM SATIVUM L.) TERHADAP JUMLAH SEL MAKROFAG PADA PENYEMBUHAN LUKA INSISI GINGIVA MARMUT (CAVIA PORCELLUS) Poernomo, Hendri; Taha Ma'ruf, Mochammad
Interdental: Jurnal Kedokteran Gigi Vol 16 No 2 (2020): Interdental Jurnal Kedokteran Gigi (IJKG)
Publisher : Faculty of Dentistry, Mahasaraswati Denpasar University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46862/interdental.v16i2.1065

Abstract

Surgical with an incision or tissue incision process can cause injury or tissue damage to the oral cavity, especially the gingiva. Wound healing can last a long time, this condition can increase the potential for complications such as infections and less blood supply. Garlic contains several active substances including flavonoids, tannins, phenols and alkaloids, and organosulfur compounds namely allicin. The content is believed to stimulate macrophage cells and help the work of macrophages in cleaning the wound area so that it accelerates into the phase of proliferation and wound healing. The research method was experimental laboratory research with a post-test design group. The results showed that the average number of macrophage cells in the control group CMC-Na 2% 97,50 cells, mean group of 40% garlic extract gel was 58,83 cells, mean group of 50% garlic extract gel was 18,00 cells, mean 60% garlic extract gel group was 7,83 cells. The results showed that there are significant differences (ρ <0,05) in the four study groups. Garlic extract gel concentration of 60% was more effective in reducing the number of macrophage cells in guinea pig gingival incision because of the percentage of active content.
AKTIVITAS ANTIBAKTERI EKSTRAK BUAH MAHKOTA DEWA (Phaleria macrocarpa) TERHADAP Staphylococcus aureus Mochammad Taha Ma’ruf; Setiawan Setiawan; Bayu Prayoga Deta Putra
Interdental: Jurnal Kedokteran Gigi Vol. 13 No. 2 (2017): Interdental Jurnal Kedokteran Gigi (IJKG)
Publisher : Faculty of Dentistry, Mahasaraswati Denpasar University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46862/interdental.v13i2.360

Abstract

Tooth extraction though always not cause problems, but can cause some complications, one of which is endocarditis infection. The infection is caused by Staphylococcus aureus that causes abnormalities of the heart valves. The use of herbal ingredients to be an alternative to antibacterial bacteria as a result of increased resistance to antibiotics. Mahkota Dewa fruit (Phaleria macrocarpa) was selected as an antibacterial because it is active substances contains such as alkaloids, saponins, flavonoids, and polyphenols. The purpose of this study was to determine the effective concentration of the extract Mahkota Dewa fruit as an antibacterial against Staphylococcus aureus that can be made of a product in the form of a gel that can be applied to a tooth extraction wound to prevent endocarditis infection. The study is in vitro an experimental laboratory approaches Post test Only Control Group Design. Samples are distinguished by the concentration differences of the Mahkota Dewa fruit extract are 60%, 70%, 80%, 90% and 100%. The results showed that the Mahkota Dewa fruit extract concentration of 70% effective as an antibacterial against Staphylococcus aureus. The effectiveness of the extract Phaleria influenced by the ability of the active substance content of flavonoids lysis of bacterial cells.
FIKSASI TULANG DENGAN ALAT BERBAHAN DASAR POLIMER (Uji Biokompatibilitas) Mochammad Taha Ma'ruf
Interdental: Jurnal Kedokteran Gigi Vol. 14 No. 2 (2018): Interdental Jurnal Kedokteran Gigi (IJKG)
Publisher : Faculty of Dentistry, Mahasaraswati Denpasar University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46862/interdental.v14i2.371

Abstract

Bone fracture fixation device have been using rigid metallic materials such as titanium, titanium-alloy or cobalt chrome. Besides having some advantages, as the titanium fixation devices also have disadvantages. It is challenge to develop the use of polymeric materials have good biocompatibility and mechanical strength appropriate to have a bone fracture fixation devices that can be absorbed by the body, such as Polyvinyl Alcohol (PVA). The purpose of this study is to know whether the PVA-HA composite with catgut reinforced has good biocompatibility without toxicity and hypersensitivity effects in experimental animals. Biocompatibility testing include local cytotoxicity and type IV contact hypersensitivity test using wistar rats (Rattus norvegicus). Testing is done through two phases, induction or sensitization phase is by rubbing PVA-HA composite with catgut reinforced ointment puder on the ears. Local toxicity testing is done by implantation of PVA-HA composite with catgut reinforced on the back catgut wistar rats. The results showed no discoloration or induration on animal ears in all treatment and control groups on the sensitization and the elicitation phase. There were no significant differences of the thickness of the wistar rats ears from all treatment groups before and after treatment on measures 24, 48 and 72 hours (ρ >0.05). Microscopic examination showed no infiltration of acute inflammatory cells such as neutrophils, basophils or eusinofil and chronic inflammatory cell infiltration such as macrophages, lymphocytes and plasma cells. It can be concluded that the PVA-HA (60:40)composite with catgut reinforced is a material that does not cause toxicity and hypersensitivity in experimental animals, thus potentially be used as bone fractures fixation material.
EFEKTIVITAS MINYAK CENGKEH DAN PULPERYL® DALAM MENGHAMBAT AKUMULASI BAKTERI Streptococcus mutans SECARA IN VITRO Hendri Poernomo; Mochammad Taha Ma'ruf; Setiawan Setiawan; PA Nindya Winda Wati
Interdental: Jurnal Kedokteran Gigi Vol. 14 No. 2 (2018): Interdental Jurnal Kedokteran Gigi (IJKG)
Publisher : Faculty of Dentistry, Mahasaraswati Denpasar University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46862/interdental.v14i2.372

Abstract

One of the complications that can occur after tooth extraction is dry socket. Bacterial infection is one among the various causes of dry socket where Streptococcus mutans become one of the bacteria that have a role as a cause. Eugenol is the main active substancethat owned by clove oil with eugenol as antibacterial properties. The research pyupose was to determine the effectiveness of clove oil in inhibiting the accumulation of Streptococcus mutans bacteria in the dry socket. The research method used to see the inhibition of clove oil 5% also the negative control of ethanol to Streptococcus mutans bacteria in the form of clear zone using a vernier caliper. The research result shows that the clove oil 5% effective in inhibiting Streptococcus mutans, with the average inhibition zone of clove oil 5% was 15 mm. Statistical test result showed significant results (ANOVA test = 0.001 with ρ <0.05). The conclusion that can be obtained from this study was clove oil 5%may inhibit the accumulation of Streptococcus mutans bacteria in the dry socket.
THE EFFECT OF GARLIC EXTRACT GEL (Allium sativum L.) TO MACROPHAGE CELL NUMBER OF GUINEA PIG (Cavia porcellus) GINGIVAL INCISION WOUND HEALING : PENGARUH GEL EKSTRAK BAWANG PUTIH (Allium Sativum L.) TERHADAP JUMLAH SEL MAKROFAG PADA PENYEMBUHAN LUKA INSISI GINGIVA MARMUT (Cavia Porcellus) Hendri Poernomo; Mochammad Taha Ma'ruf
Interdental Jurnal Kedokteran Gigi (IJKG) Vol. 16 No. 2 (2020): Interdental Jurnal Kedokteran Gigi (IJKG)
Publisher : Fakultas Kedokteran Gigi, Universitas Mahasaraswati Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46862/interdental.v16i2.1065

Abstract

Introduction: Surgical with an incision or tissue incision process can causes injury or tissue damage to the oral cavity, especially the gingiva. Wound healing can last a long time, this condition can increase the potential for complications such as infections and less blood supply. Garlic contains several active substances including flavonoids, tannins, phenols and alkaloids and organosulfur compounds namely allicin. The content is believed to stimulate macrophage cells and help the work of macrophages in cleaning the wound area, so that it accelerates into the phase of proliferation and wound healing. Materials and method: The research method is using experimental laboratory research with post-test design group. Results: The results showed that the average number of macrophage cells in the control group CMC-Na 2% 97,50 cells, mean group of 40% garlic extract gel was 58,83 cells, mean group of 50% garlic extract gel was 18,00 cells, mean 60% garlic extract gel group was 7,83 cells. Discussion: The results of statistical tests show that there are significant differences (ρ <0,05) in the four study groups. Conclussion: Garlic extract gel in concentration of 60% was more effective in reducing the number of macrophage cells in guinea pig gingival incision because the percentage of active content.
RED GINGER RHIZOME EXTRACT GEL IMPROVES COLLAGEN DENSITY POST EXTRACTION OF GUINEA PIG TEETH : GEL EKSTRAK RIMPANG JAHE MERAH MENINGKATKAN KEPADATAN KOLAGEN PASCA EKSTRAKSI GIGI MARMUT Sulistiawati Putu Dewi; Mochammad Taha Ma’ruf
Interdental Jurnal Kedokteran Gigi (IJKG) Vol. 17 No. 1 (2021): Interdental Jurnal Kedokteran Gigi (IJKG)
Publisher : Fakultas Kedokteran Gigi, Universitas Mahasaraswati Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46862/interdental.v17i1.1190

Abstract

Introduction: tooth extraction can cause injury involving the bone structure and soft tissue of the oral cavity. Tooth extraction can cause various complications, one of which is bleeding. Red ginger is a type of spice that ismost widely used in various food and beverage recipes. Red ginger is commonly used by the public as a cold, digestive, antipyretic, anti-inflammatory, and analgesic drug. Various studies have shown that ginger has antioxidant properties, flavonoids, and oleoresins found in the rhizome. The purpose of this study was to determine the effect of the concentration of red ginger extract (Zingiber Officinale Varr. Rubrum) on collagen density after extraction of guinea pig teeth (Cavia porcellus). Materials and method: the method of this research is an experimental in vivo laboratory with a post-test-only control group design. The hypothesis test was carried out by the One Way Anova test and was carried out on 24 male guinea pigs. The experimental animals were divided into 4 groups which were distinguished by concentration, 10%, 20%, 30%, and the control group was given 2% CMC-Na gel respectively. Results and discussions: The results showed that red ginger extract gel concentrations of 10%, 20%, and 30% can increase collagen density compared to CMC-Na 2%. Conclusion: the red ginger extract gel with a concentration of 30% was most effective at increasing collagen density compared to concentrations of 10% and 20%.
Co-Authors Alva Edy Tontowi Bayu Prayoga Deta Putra Hendri Poernomo Laksmi Novrina Dewi Marsetyawan Heparis Nur Ekanda Soesatyo Metta Liliana Mochammad Yuwono Nabila, Aghnia PA Nindya Winda Wati Putra, Bayu Prayoga Deta Putu Sulistiawati Dewi Setiawan Setiawan Setiawan Setiawan Wati, PA Nindya Winda Widowati Siswomihardjo Zulni, Shalsa Septia