Suparyono Saleh
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PENGARUH RISEDRONATE BISPHOSPHONATE TERHADAP ENZIM TRAP (EKSPRESI OSTEOKLAS) DI SEKITAR SUBSTRUKTUR IMPLAN GIGI ENDOSSEOUS: EFFECT OF RISEDRONATE BISPHOSPHONATE ON ENZYM TRAP (OSTEOCLAST EXPRESSION) SURROUNDINGS SUBSTRUCTURE ENDOSSEOUS DENTAL IMPLANT Suparyono Saleh; Iwan Dwi Prahasto; Munakhir Mudjosemedi; Ika Dewi Ana
Dentika: Dental Journal Vol. 18 No. 1 (2014): Dentika Dental Journal
Publisher : TALENTA

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (365.096 KB) | DOI: 10.32734/dentika.v18i1.1950

Abstract

Keberhasilan gigi tiruan tanam, tergantung pada proses oseointegrasi, yaitu suatu hubungan langsung antara bagianimplan gigi yang tertanam di dalam tulang rahang (substructure) dengan jaringan tulang disekitarnya tanpa ada pengaruhdari jaringan lunak yang lain. Osteoklas berperan penting dalam proses oseointegrasi karena sel tersebut mempunyaikemampuan untuk meresorpsi tulang. Tujuan penelitian ini untuk mengetahui pengaruh sediaan farmasi Risedronate(Ris) yang mempunyai kemampuan untuk mencegah proliferasi osteoklas. Tiga puluh enam tikus Wistar berumur 9-10minggu dengan berat antara 280-300 gram dibagi menjadi 4 kelompok (n= 9), setiap kelompok dibagi lagi menjadi 3subkelompok (n= 3). Kelompok I sebagai kontrol dengan perlakuan injeksi 0,05 mL cairan 0,9% NaCL sementarakelompok II, III, dan IV diinjeksi 0,05 mL sediaan Ris dengan konsentrasi 250, 500, dan 1000 µmol/L secara berurutan.Injeksi dilakukan setiap 3 hari sekali dengan lama waktu pemberian injeksi yang berbeda-beda, yaitu 14, 28, dan 56 hari.Analisis statistik menggunakan Uji Kruskal-Wallis dan U Mann-Whitney. Hasil penelitian menunjukkan terdapatperbedaan yang bermakna pada kelompok dosis Ris (p< 0,05) dan tidak signifikan pada kelompok hari amatan (p> 0,05).
Prosthetic rehabilitation of nasomaxillary defect with TAD retained surgical obturator followed by hollow bulb definitive obturator and immediate lower denture Wijaya, Agustinus Kenny; Barunawati, Sri Budi; Fransiscus Wihan Pradana; Suparyono Saleh
Indonesian Journal of Prosthodontic Vol 5 No 2 (2024): December 2024
Publisher : Indonesia Prosthodontic Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46934/ijp.v5i2.217

Abstract

The integrity and functionality of the oral cavity may be compromised by nasomaxillary defects, such as speech, mastication, deglutition, and esthetics. Early prosthodontic rehabilitation can improve quality of life and lessen the psychological harm caused by the surgical treatment. A 70-years-old female patient was referred to the Department of Prosthodontics RSUP Dr. Sardjito Yogyakarta with chief complaints of nasal obstruction, and right-side swelling of the face. Extraoral examination revealed facial asymmetry due to swelling of the right buccal region. On intraoral examination, showing a large, firm mass extending from right palate to the midline. A multidisciplinary approach with ENT is required for the surgical treatment. A surgical obturator was made before the surgery, and immediately inserted after with TAD as a retention device. Three months later, a hollow bulb obturator and immediate lower denture was fabricated so the functional capabilities of speech, mastication, deglutition, and esthetics can be restored. Keywords: surgical obturator, maxillofacial prostheses, definitive obturator, hollow bulb
Improving obturator retention in hollow palatal defect using silicone soft-reliner Yuwono, William; Endang Wahyuningtyas; Intan Ruspita; Suparyono Saleh
Indonesian Journal of Prosthodontic Vol 6 No 1 (2025): June 2025
Publisher : Indonesia Prosthodontic Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46934/ijp.v6i1.278

Abstract

Defect in the intraoral maxilla or palate resulting from surgical hemimaxillectomy can lead to difficulties in chewing, speaking, swallowing, and may also affect psychological function. One effective rehabilitation method for restoring oral function is the obturator prosthesis. This case report discusses the rehabilitation of a palatal defect following hemimaxillectomy, utilizing a hollow bulb obturator with a silicone-based soft liner and incorporating extracted posterior teeth as immediate dental provisions for relining an interim denture. The patient, a 46-year-old male, presented at Universitas Gadjah Mada Dental Hospital with complaints of discomfort, instability, and inadequate palatal coverage from his prosthetic obturator after undergoing tumor removal in the right maxillary area two years earlier. Examination revealed a significant hollow defect under the palate, exposure of the inferior nasal conchae, and mobility in the first and second premolars on the right side. Panoramic radiographs indicated loss of ridge support around these teeth. To enhance retention and comfort, a silicone-based soft liner was applied to the obturator. The use of extracted teeth proved beneficial for improving occlusal force, strength, and aesthetics. Thus, a hollow ground obturator with a soft reliner is recommended for effective rehabilitation post Class II Aramany hemimaxillectomy. Keywords: Palatum defect, Obturator, Hollow bulb, Soft-reliner