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All Journal Indonesian Journal of Pharmaceutical Science and Technology SWARNA: Jurnal Pengabdian Kepada Masyarakat Jurnal Riseta Naturafarm
FITRIANI, VICTORIA YULITA
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Religion Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Civil Engineering, Building, Construction & Architecture Computer Science & IT Economics, Econometrics & Finance Health Professions Languange, Linguistic, Communication & Media Medicine & Pharmacology Public Health

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The Potential of Probiotic Role in Tuberculosis Therapy : A Narrative Review Fitriani, Victoria yulita; Suprapti, Budi; Amin, Muhammad
Indonesian Journal of Pharmaceutical Science and Technology 2024: Suppl. 6, No. 1 (Special Issue for Mulawarman Pharmaceutical Conference)
Publisher : Indonesian Journal of Pharmaceutical Science and Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/ijpst.v6i1.53635

Abstract

Tuberculosis is an infectious disease that is a leading cause of death globally, as well as one of the top ten causes of death from a single infectious agent. Antibiotics treatment for tuberculosis reduces pro-inflammatory cytokines, which is one of the reasons for dysbiosis. The proportion of Actinobacteria, Firmicutes, and Bacteroidetes in the gut microbiota distinguishes between drug-sensitive and drug-resistant tuberculosis. The gut–lung axis theory explains how tuberculosis alters the gut microbiota while also altering the immune response. Probiotics have immunostimulatory and immunoregulatory properties that affect the immune system. The gut-lung axis is a two-way system that enables microbial products, endotoxins, metabolites, hormones, and cytokines to reach the bloodstream that connects the intestines and lungs, where they exert effects on both. According to the gut–lung axis theory, probiotics may play a role in tuberculosis immune responses. This review includes studies conducted in English and Indonesian from 2010-2022. The Cochrane Library, Scopus, Medline, PubMed, and grey literature databases will be used in the review. Studies that use specimens from pulmonary tuberculosis patients, healthy volunteers induced by Mycobacterium tuberculosis, volunteers with a history of pulmonary tuberculosis disease, and volunteers who had close contact with pulmonary tuberculosis patients were considered eligible. The current review highlights the immune modulation induced by probiotics usage in tuberculosis. Accordingly, probiotics have been shown to enhance the immune response against tuberculosis. More studies are needed to understand probiotic’s role in different types of tuberculosis, and the influence of different probiotic bacteria on immune modulation.
Sosialisasi Monkeypox dan Edukasi Pola Hidup Sehat Pada Tim Penggerak Pemberdayaan Kesejahteraan Keluarga (PKK) Kelurahan Rapak Dalam Kota Samarinda Arief, Maryam Jamila; Fitriani, Victoria Yulita; Sinthary, Venna; Helmi, Helmi; Almeida, Maria
SWARNA: Jurnal Pengabdian Kepada Masyarakat Vol. 3 No. 11 (2024): SWARNA: Jurnal Pengabdian Kepada Masyarakat, November 2024
Publisher : LPPM Sekolah Tinggi Ilmu Ekonomi 45 Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Monkeypox merupakan penyakit infeksi zoonosis yang disebabkan oleh virus monkeypox dan telah menjadi perhatian global akibat peningkatan kasus di berbagai negara, termasuk Indonesia. Penularan monkeypox terjadi melalui kontak langsung dengan hewan atau manusia yang terinfeksi, droplet, atau penggunaan bersama alat makan. Peningkatan kesadaran masyarakat, khususnya melalui edukasi pola hidup sehat, menjadi strategi penting dalam pencegahan penyakit ini. Kegiatan ini bertujuan untuk meningkatkan pengetahuan masyarakat tentang monkeypox dan pentingnya pola hidup sehat sebagai upaya pencegahan. Metode yang digunakan meliputi sosialisasi interaktif dan penyuluhan yang disertai evaluasi melalui pretest dan post-test kepada anggota Tim Penggerak PKK Kelurahan Rapak Dalam, Kota Samarinda. Hasil evaluasi menunjukkan adanya peningkatan nilai post-test sebesar 15,63% dibandingkan nilai pretest, yang mengindikasikan peningkatan pengetahuan peserta setelah mengikuti kegiatan. Hal ini menunjukkan bahwa sosialisasi dan edukasi pola hidup sehat efektif dalam meningkatkan kesadaran masyarakat terhadap pencegahan monkeypox. Kesimpulannya, program ini memberikan dampak positif dalam meningkatkan pengetahuan peserta dan memperkuat kemampuan masyarakat dalam melakukan tindakan pencegahan. Edukasi seperti ini sangat penting untuk diterapkan secara luas guna memitigasi penyebaran monkeypox dan penyakit menular lainnya.
Metabolit Sekunder dan Aktivitas Antibakteri Ekstrak Metanol Daun Kamboja Putih (Plumeria acuminata Ait) Terhadap Beberapa Bakteri Uji Farid, Riza; Fitriani, Victoria Yulita; Ibrahim, Arsyik
Jurnal Riseta Naturafarm Vol. 1 No. 1 (2024): Jurnal Riseta Naturafarm
Publisher : B-Creta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70392/mrvbwp06

Abstract

Kamboja (Plumeria acuminata Ait) plant is traditional medicine used as medication for ulcer and abscess. Steroid and tanin is component of chemical compound in kamboja leaves that supposed to have antibacterial activity. This study aims to determine the content of secondary metabolites and effective concentration of methanol extracts of kamboja leaves as antibacterial. Identification contains of secondary metabolites by used reagent Mayer, Dragendorf, Liebermann-Burchard, FeCl, Mg powder and HCl. Analysis of secondary metabolites characterized by the presence of sediment or froth. The antibacterial activity test carried out by agar diffusion method. Inhibition zone is analyzed by Anava and Duncan test. Secondary metabolite the compound containing steroid and tanin. The effective concentration of 40% were significantly different with a value of p = 0.00 (p<0.05) on the growth of Streptococcus mutans and Staphylococcus aureus bacteria and a concentration of 30% is very significantly different from the value of p = 0.00 (p<0.05) on the growth of Escherichia coli bacteria in vitro.
Co-Authors Almeida, Maria Arief, Maryam Jamila Budi Suprapti Farid, Riza Helmi Helmi Ibrahim, Arsyik Muhammad Amin Sinthary, Venna