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Journal : Indonesian Journal of Pharmaceutical Science and Technology

Potential Indonesian Medicinal Plants on Aphrodisiac Activity Prasetya, Fajar; Bahar, Zulhaerana; Fricillia, Onny Ziasti; Indriyanti, Niken
Indonesian Journal of Pharmaceutical Science and Technology 2024: Suppl. 6, No. 1 (Special Issue for Mulawarman Pharmaceutical Conference)
Publisher : Indonesian Journal of Pharmaceutical Science and Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/ijpst.v6i1.55179

Abstract

The use of Indonesian medicinal plants in empirical ingredients as a jamu in Indonesian tradition is very interesting to be explored. One of them is the use of jamu for aphrodisiac activity. This research is aimed to determine the data about the diversity of Indonesian medicinal plants used for aphrodisiacs. Some aspects reviewed were empirical use, safety data, and scientific research data. The method used in this research is narrative review by using search engine Sciencedirect, Pubmed, Springerlink, and Google Scholar in 24 years (2000-2024). The literature review resulted in 20 Indonesian medicinal plants, which were very potent for aphrodisiac. The plants are Areca catechu L., Pimpinella panatjan Mirb, Zingiber officinale, Dendrocalamus asper, Eurycoma longifolia Jack, Sanrego, Anacardium occidentale L., Imperata cylindrica L., Allium sativum L., Ocimum sanctum, Piper retrofractum Vahl., Piper nigrum L., Eugenia caryophyllata, Myristica Fragans, dan mangrove mangrove M. muticus, R. mucronata, R. apiculata, A. aureum, D. trifoliata and B. parviflora. Therefore, it will be used as a reference based for the further research.   
ANTI-INFLAMMATORY AND ANALGESIC ACTIVITY OF RETICULATED PYTHON FAT OIL (MALAYOPYTHON RETICULATUS) IN VIVO EVALUATION Hajrah, Hajrah; Febriani, Dina Arindha; Indriyanti, Niken
Indonesian Journal of Pharmaceutical Science and Technology 2024: Suppl. 6, No. 1 (Special Issue for Mulawarman Pharmaceutical Conference)
Publisher : Indonesian Journal of Pharmaceutical Science and Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/ijpst.v6i1.55201

Abstract

Empirically, python fat oil (Malayopython reticulatus) is used by local people in Miau Baru, Kongbeng, East Kalimantan to treat swelling and inflammation. The purpose of this study was to determine the physical characteristics, anti-inflammatory, and analgesic activities of the python fat oil in reducing pain and inflammation. The methods that are used for determining physical characteristics are organoleptic test, density test, viscosity test, pH test, and refractive index test. The method that is used for determining anti-inflammatory activities is the paw edema method, which is induced by lambda carrageenan, and for analgesic activities using the hot plate method. The results obtained are that python oil has a yellow-orange color, a rancid odor, and has a bland taste, has a density of 0.870 g/mL with a pH of 4.1. The viscosity of the python fat oil is 2.2 Pa.s with a refractive index of 1.463. The percentage of edema formed at 5% concentration was 0.33%, 10% concentration was 0.43%, and 15% concentration was 0.25%. A recent increase in survival time in analgesic testing with a 5% concentration of 4.44%, a 10% concentration of 3.87%, and a 15% concentration of 3.11%. It was concluded that python fat oil has anti-inflammatory and analgesic activity.
Weight Loss Activity of Boesenbergia rotunda, Zingiber cassumunar, and Hibiscus sabdariffa Combination Extract on Zebrafish Model Indriyanti, Niken
Indonesian Journal of Pharmaceutical Science and Technology Vol 12, No 1 (2025)
Publisher : Indonesian Journal of Pharmaceutical Science and Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/ijpst.v12i1.50575

Abstract

Boesenbergia rotunda, Zingiber cassumunar, and Hibiscus sabdariffa are potential medicinal plants to be developed as weight loss agent. This research aimed to determine weight loss activity of the 3 plants in combination. The model used was zebrafish wild type. The protocol was approved by the Ethics Committee of Health Research, Faculty of Pharmacy, Mulawarman University. The extraction method was decocta. The flavonoid and phenolic contents were calculated using standard method of analysis in Indonesian Herbal Pharmacopoeia.  The results of rendemen and total flavonoid/phenolic content (TFC/TPC) calculations are Boesenbergia extract 2,7% with the TFC of 49,7 mg/g; Zingiber cassumunar extract 6,5% with the TPC of 41,2 mg/g; Hibiscus extract 31,6% with the TFC of 91,2 mg/g. It forms as dry extracts, brown colour, and hygroscopic. The average of weight loss of zebrafish in 2 weeks treatment is 9-16% in sample 1 group; 28,5% in sample 2 group; and no lowering body weight on sample 3 group. The sample 1 and 2 are promising compared to orlistat activity, 32% weight loss. In conclusion, the highest weight loss activity is in sample 2 which is consisted of combination of Boesenbergia extract and Zingiber cassumunar extract.@font-face {font-family:"Cambria Math"; panose-1:2 4 5 3 5 4 6 3 2 4; mso-font-charset:0; mso-generic-font-family:roman; mso-font-pitch:variable; mso-font-signature:3 0 0 0 1 0;}@font-face {font-family:Calibri; panose-1:2 15 5 2 2 2 4 3 2 4; mso-font-charset:0; mso-generic-font-family:swiss; mso-font-pitch:variable; mso-font-signature:-536859905 -1073732485 9 0 511 0;}p.MsoNormal, li.MsoNormal, div.MsoNormal {mso-style-unhide:no; mso-style-qformat:yes; mso-style-parent:""; margin:0cm; margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:10.0pt; font-family:"Calibri",sans-serif; mso-fareast-font-family:Calibri; mso-bidi-font-family:Arial; mso-ansi-language:EN-US;}.MsoChpDefault {mso-style-type:export-only; mso-default-props:yes; font-size:10.0pt; mso-ansi-font-size:10.0pt; mso-bidi-font-size:10.0pt; font-family:"Calibri",sans-serif; mso-ascii-font-family:Calibri; mso-fareast-font-family:Calibri; mso-hansi-font-family:Calibri; mso-bidi-font-family:Arial; mso-ansi-language:EN-US;}div.WordSection1 {page:WordSection1;}