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Edukasi Pemanfaatan Bahan Alam Menjadi Sediaan Farmasi pada Masyarakat Desa Sukaraja Kecamatan Sepaku Kab. Penajam Paser Utara Islamudin Ahmad; M. Arifuddin; Nurul Muhlisa Mus; Faizatun Maulidha; Karisman Karisman; Michael Rendy Yakubus; Aji Ayatullah; Dandy Zwageri; Erwin Samsul
Jurnal Pengabdian Masyarakat (ABDIRA) Vol 3, No 2 (2023): Abdira, April
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/abdira.v3i2.320

Abstract

Traditional medicine has the opportunity to be used in preventive promotive efforts, especially to maintain immunity as one of the cultural traditions of the community that has been passed down from generation to generation by utilizing local wisdom. The diversity of medicinal plants that exist in East Kalimantan encourages the community to play an active role in processing and developing these plants into products that can help maintain health. One village that has a vision and mission to improve the quality of agricultural, animal husbandry, plantation and fisheries as well as developing human resources in the village is Sukaraja Village. Education on the utilization of natural medicinal substances into pharmaceutical preparations is carried out using power point media using the lecture method. This activity ran smoothly which was shown by the enthusiasm of the people of Sukaraja Village in listening to explanations and actively asking the speakers, especially regarding various kinds of medicinal plants that have the potential to be made into pharmaceutical preparations so that they are able to develop products based on natural ingredients in a variety of ways and can become a mainstay commodity by utilizing plants originating from natural materials around Sukaraja Village.
Home Pharmacy Care Penyakit Tidak Menular di Samarinda Niken Indriyanti; Erwin Samsul; Vita Olivia Siregar; Rezekilah Rezekilah; Andi Tenri Kawareng; Muhammad Faisal; Juniza Firdha Suparningtyas
Jurnal Pengabdian Masyarakat (ABDIRA) Vol 3, No 4 (2023): Abdira, Oktober
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/abdira.v3i4.232

Abstract

Home pharmacy care on non-contagious patients is necessary to increase the quality of therapeutic outcome. This program was done in a district in Samarinda. Participant selection was done by participating of nearest primary health facility. Permissions were given from the district and the nearest health facility. Three visitations were done for determination, education, and evaluation steps. The personal education during this program shows a positive impact on the own responsibility of self adherence under drug regimen. Generally, medical examination on blood pressure, blood glucose, and others are better after effective education of this program. Education output of this program is useful to increase patient’s adherence to drug regimen and healthy lifestyle.
Gerakan Masyarakat Bijak Konsumsi Obat (GMBKO) pada Masyarakat Desa Liang Ulu Kecamatan Kota Bangun Kabupaten Kutai Kartanegara Islamudin Ahmad; M. Arifuddin; Erwin Samsul; Faizatun Maulidha; Nurul Muhlisa Mus
Jurnal Pengabdian Masyarakat (ABDIRA) Vol 3, No 4 (2023): Abdira, Oktober
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/abdira.v3i4.382

Abstract

Medicine is an inseparable part of society because of its usefulness in reducing symptoms or curing a disease. In order for medicines to provide maximum results, a correct understanding of the rules for consuming medicines, whether in the form of synthetic drugs or those of natural origin from plants, is required. One area that is rich in medicinal plants, including endemic Kalimantan medicinal plants such as kratom and has attention to the use of medicinal plants to improve health status, is Liang Ulu Village. To provide understanding and increase the knowledge of the people of Liang Ulu Village, Kota Bangun District, Kutai Kartanegara Regency regarding the proper and correct use of medicines and medicinal plants, community service activities were carried out in the form of the Community Wisely Consuming Medicines (MBKO) movement. The service methods used include delivering material, discussions, and distributing posters and leaflets. Success parameters are seen based on pre and post-test data to measure the increase in public understanding. The results of community service activities show an increase in knowledge from 62.56% to 82%.
Naphthalene Derivates from Bawang Tiwai Bulb Eleutherine Bulbosa in Borneo Salam, Supriatno; Hikmawan, Baso Didik; Samsul, Erwin; Herman, Herman; Ahmad, Islamudin; Rijai, Laode; Nafiah, Mohd Azlan
al Kimiya: Jurnal Ilmu Kimia dan Terapan Vol 11, No 1 (2024): al Kimiya: Jurnal Ilmu Kimia dan Terapan
Publisher : Department of Chemistry, Faculty of Science and Technology, UIN Sunan Gunung Djati Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15575/ak.v11i1.35515

Abstract

Naphthalene derivative compounds named Eleutherol (1) and Eleutherol C (2) have been isolated from Bawang Tiwai Bulb Eleutherine bulbosa. We tested its cytotoxic activity against T47D breast cancer cells in vitro after isolating compounds 1 and 2 from the EtOH extract using conventional chromatography methods. Their chemical structures were elucidated based on spectroscopic analysis, including IR, HR-TOFMS, 1D, and 2D NMR, and by comparison to those related spectra previously reported. Compounds 1 and 2 were tested for their cytotoxic effects against T47D breast cancer cells and showed moderate cytotoxicity against T47D breast cancer cells with IC50 values of 117.15 and 80.21 µM, respectively, compared with cisplatin 24.07 µM.
Potential and Constraints of Biopharmaceutical Plants in East Kalimantan Province Junaidin Junaidin; Supriatno Salam; Erwin Samsul
Journal of Tropical Pharmacy and Chemistry Vol. 6 No. 1 (2022): J. Trop. Pharm. Chem.
Publisher : Faculty of Pharmacy, Universitas Mulawarman, Samarinda, Indonesia, 75117, Gedung Administrasi Fakultas Farmasi Jl. Penajam, Kampus UNMUL Gunung Kelua, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jtpc.v6i1.350

Abstract

Biopharmaceutical plants (drugs) in East Kalimantan Province have tremendous potential for the Farmers' Economy in particular and the Economy of Society in general. Farmers have not felt this potential because it faces existing obstacles. In this study, the Pharmaceutical Business Laboratory, Faculty of Pharmacy, Mulawarman University, will be analyzed for its role in finding solutions to existing obstacles. Research results are expected to be helpful in terms of the resource-advantage theory and in terms of Implications that can be done by Stakeholders, which aim that the potential of Biopharmaceutical Crops can bring the welfare of Farmers and Communities.
Aktivitas Antidiabetes Serbuk Semut Jepang (Tenebrio molitor Linn.) pada Mencit Swiss Webster Jantan yang Diinduksi Aloksan Erwin Samsul; Andreanus A. Soemardji; Siti Kusmardiyani
Jurnal Sains dan Kesehatan Vol. 2 No. 4 (2020): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v2i4.150

Abstract

Diabetes mellitus is a disease caused by metabolic disorders with hyperglycemia conditions that can occur due to impaired insulin secretion, insulin sensitivity or both. Semut Jepang (SJ) are used by people of Indonesians as a drug to reduce blood sugar levels, but have not been scientifically studied as antidiabetic. Therefore, this study aims to examine the antidiabetic activity of Japanese ant powder in mice. Method: The study was carried out using the antihyperglycemic method in mice induced by alloxan. In the antihyperglycemic method in alloxan induced mice, mice were divided into 6 groups, namely 1% normal Na CMC control group (not alloxan induced), 1% Na CMC pain control group (alloxan induced), glibenclamide 5 mg / kg bw comparison group, and 3 test groups were given Japanese ant powder with a dose of 9 mg / kg bw (SJ 9), 45 mg / kg bw (SJ 45), and 90 mg / kg bw (SJ 90). Blood glucose levels were measured on the first day, day 3, day 7, and day 14. Results: The use of SJ 45 and SJ 90 were better in lower blood glucose compared to the glibenclamide comparison group. Conclusion: Japanese ant powder at doses of 45 and 90 mg / kg bw give an antidiabetic effect that is better than glibenklamid 5 mg / kg bw in reducing blood glucose levels in mice induced by alloxan. Keyword : Semut jepang powder, diabetes mellitus, blood glucose level
Uji Aktivitas Anthelmintik Perasan Buah Mengkudu (Morinda citrifolia) Secara In Vivo: In Vivo Anthelmintic Activity Test of Morinda citrifolia Fruit Juice Herlina Argantari Basuki; Erwin Samsul; Rolan Rusli
Jurnal Sains dan Kesehatan Vol. 3 No. 6 (2021): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v3i6.710

Abstract

Mengkudu (Morinda citrifolia) merupakan salah satu tanaman yang dipercaya oleh masyarakat memiliki banyak manfaat bagi kesehatan. Salah satu manfaat dari buah mengkudu yaitu sebagai obat cacing. Tujuan dari penelitian ini adalah untuk mengetahui aktivitas anthelmintik pada perasan buah mengkudu dan mengetahui konsentrasi efektif dalam membunuh cacing secara in vivo. Hasil pengujian menunjukkan adanya aktivitas anthelmintik pada perasan buah mengkudu secara in vivo yang dibuktikan dengan menggunakan uji One Way ANOVA yang dimana tidak ada perbedaan signifikan (p>0,05) antara variasi konsentrasi perasan buah mengkudu dengan kontrol positif yaitu pirantel pamoat. Hasil pengujian menunjukkan bahwa konsentrasi perasan buah mengkudu yang paling efektif dalam membunuh cacing yaitu terdapat pada konsentrasi 75% dan 100% dilihat dari rasio kematian cacing.
Upaya Peningkatan Kesehatan Melalui Pemeriksaan Kesehatan Gratis pada Masyarakat Desa Bangun Rejo Kecamatan Tenggarong Seberang Kabupaten Kutai Kartanegara sebagai Upaya Deteksi Dini Penyakit Tidak Menular Arifuddin, Muhammad; Samsul, Erwin; Riki; Rija'i, Hifdzur Rashif; Rusli, Rolan; Ibrahim, Arsyik; Febrina, Lizma; Bone, Mahfuzun; Junaidin; Herman; Rusman, Arman; Hikmawan, Baso Didik; Ahmad, Islamudin
Jurnal Abdita Naturafarm Vol. 2 No. 1 (2025): J Abdita Naturafarm
Publisher : B-Creta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70392/jan.v2i1.1925

Abstract

Non-communicable diseases (NCDs) have become a significant global health challenge. Conditions such as heart disease, diabetes, and hypertension contribute to more than 70% of deaths worldwide. This community service activity aims to provide free health screenings to the community, particularly to the residents of Desa Bangun Rejo, with the goal of early detection of NCDs. The community service activities involved health screenings followed by direct education to the participants. The results showed that 40 participants attended and gained knowledge about their current health conditions, including blood pressure, blood glucose levels, and uric acid levels. The findings from the health screenings will serve as a reference for participants to understand the importance of regular health check-ups in mitigating future risks Penyakit tidak menular (PTM) menjadi salah satu tantangan kesehatan global yang signifikan. termasuk penyakit jantung, diabetes, dan hipertensi menyumbang lebih dari 70% kematian di seluruh dunia. Kegiatan pengabdian kepada masyarakat ini bertujuan untuk memberikan pemeriksaan Kesehatan gratis kepada masyarakat khususnya masyarakat Desa Bangun Rejo yang bertujuan untuk deteksi dini PTM. Metode kegiatan pengabdian yang dilakukan berupa pemeriksaan Kesehatan dan dilanjutkan pemberian edukasi langsung kepada peserta. Hasil kegiatan pengabdian kepada masyarakat ini menunjukkan peserta yang hadir sebanyak 40 orang mengetahui tentang kondisi saat ini berupa tekanan darah, kadar glukosa darah, dan asam urat. Hasil pemeriksaan yang didapatkan dijadikan sebagai rujukan untuk peserta lebih memahami pentingnya melakukan pemeriksaan kesehatan secara rutin guna menanggulangi resiko yang lebih besar untuk kedepannya
An Innovative Strategy for the Green Synthesis of Nanochitosan Using Plant Extracts and Their Possible Applications: A Review Riki, Riki; Ahmad, Islamudin; Herman, Herman; Ibrahim, Arsyik; Rusman, Arman; Samsul, Erwin; Rusli, Rolan; Arifuddin, Muhammad; Junaidin, Junaidin; Bone, Mahfuzun; Rijai, Hifdzur Rashif; Hikmawan, Baso Didik
Indonesian Journal of Chemistry Vol 25, No 2 (2025)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijc.100148

Abstract

The numerous applications of nanochitosan in a variety of sectors, including medicine, food, and agriculture, attract researchers to work toward the development of environmentally favorable, safe, and efficient synthesis methods. Currently, a biological approach is being developed to synthesize nanochitosan to address the limitations of conventional methods. The synthesis of biogenic pathways employs biological entities, including plant extracts and microorganisms, as nanoparticle-forming agents. The use of extracts is more desirable due to the simple working procedure, the absence of hazardous chemicals, the economic benefits, and the use of basic equipment. This article highlights the role of biomolecules in plant extracts, including polyphenols, terpenoids, citric acid, alkaloids, and polysaccharides, in the synthesis of nanochitosan. Nanoparticle preparation protocols and characterization using zeta potential analysis techniques, scanning electron microscopy (SEM), transmission electron microscopy (TEM), UV-visible spectroscopy, and Fourier transform infrared spectroscopy (FTIR) are briefly described. The potential applications of green nanochitosan are also discussed, considering the results of biological activity testing and the potential mechanisms associated with these activities. According to the results of numerous studies highlighted in this review, nanochitosan synthesis utilizing plant extracts appears to be a promising alternative approach to conventional methods.
Aktivitas Antihiperglikemia Infusa Daun Sambung Nyawa (Gynura Procumbens) dengan Metode Toleransi Glukosa pada Mencit Jantan (Mus Musculus): Antihyperglycemic Activities of Sambung Nyawa Leaves (Gynura Procumbens) Infusion using a Glucose Tolerance Method in Male Mice (Mus Musculus) Ridhotulloh, Yusuf Isro; Rijai, Laode; Mus, Nurul Muhlisa; Arifuddin, M.; Ibrahim, Arsyik; Ahmad, Islamudin; Herman, Herman; Hikmawan, Baso Didik; Junaidin, Junaidin; Febrina, Lizma; Faisal, Muhammad; Rusman, Arman; Riki, Riki; Almeida, Maria; Bone, Mahfuzun; Arifian, Hanggara; Samsul, Erwin
Jurnal Sains dan Kesehatan Vol. 7 No. 2 (2025): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v7i2.2421

Abstract

Hyperglycemia is a condition where blood sugar increases significantly which can lead to diabetes mellitus. Sambung Nyawa (Gynura Procumbens) leaves are a plant that is empirically believed to reduce hyperglycemia and has been scientifically proven based on several studies, however there has been no research that provides information about sembung nyawa leaves in infusion form. This study aims to determine the content of secondary metabolites in the infusion of the leaves of Gynura Procumbens and its antihyperglycemia activity in male males. This study consisted of phytochemical and antihyperglycemia screening using a tolerance method induced by glucose monohydrate at a dose of 2g/kgBW. The test group consisted of a negative control group (Na CMC 1%), a positif group (Glibenclamide), and 3 groups of sambung nyawa leaf infusion (5%, 10%, 15%). The results of the research showed that the infusion of sembung nyawa leaves contained secondary metabolites, namely tannins, phenolics, flavonoids and saponins. The effect of reducing blood sugar levels in test animals showed a significant reduction (0.00<0.05) at a 10% concentration infusion compared to the negative control and not significant to the positive control. The conclusion shows that the infusion of sambung nyawa leaves has an antihyperglycemic effect. Keywords:          Antihyperglycemic, Sambung Nyawa Leaves, Glucose Monohydrate   Abstrak Hiperglikemia merupakan kondisi peningkatan gula darah yang cukup signifikan yang akan berubah menjadi kondisi diabetes mellitus. Daun sambung nyawa (Gynura Procumbens) merupakan tumbuhan yang dipercaya secara empiris menurunkan hiperglikemia dan terbukti secara ilmiah berdasarkan beberapa penelitian dalam bentuk ekstrak. Penelitian ini bertujuan mengetahui kandungan metabolit sekunder pada infusa daun sambung nyawa dan aktivitas antihiperglikemia pada mencit jantan. Penelitian ini terdiri dari skrining fitokimia dan antihiperglikemia menggunakan metode toleransi yang dinduksi glukosa monohidrat dengan dosis 2g/kgBB. Kelompok uji terdiri dari kelompok kontrol negatif (Na CMC 1%), positif (Glibenklamid), dan 3 kelompok infusa daun sembung nyawa (5%, 10%, 15%). Hasil penelitian menunjukkan infusa daun sambung nyawa mengandung metabolit sekunder yaitu tanin, fenolik, flavonoid dan saponin. Efek penurunan kadar gula darah pada hewan uji menunjukkan penurunan yang signifikan (0,00<0,05) pada infusa konsentrasi 10% dibandingkan dengan kontrol negatif dan tidak signifikan terhadap kontrol positif. Kesimpulan menunjukkan bahwa infusa daun sambung nyawa mempunyai efek antihiperglikemia. Kata Kunci:         Antihiperglikemia, Daun Sambung Nyawa, Glukosa Monohidrat  
Co-Authors Agus Setiawaty Agustina, Inayah Yuli Aji Ayatullah Al Dzaky, Audric Almeida, Maria Amiruddin, Widya Salsabila Putri Andi Tenri Kawareng Andreanus A. Soemardji Ardhito, Willy Arifian, Hanggara Arifuddin, M Arifuddin, Muhammad Atmadja, Meilda Keysia Angelica Badawi, Satriani Baso Didik Hikmawan Basongan, Oktariani Bone, Mahfuzun Dandy Zwageri Dewi, Jingga Apriani Jevita Faizatun Maulidha Farah, Harra Ismi Febrianur, Hana Giska Febrina, Lizma Fitri Hasanah Gala, Kretentia Aprilia Gunawan, Jevon Ecclesia Hajrah Hajrah, Hajrah Harludi, Theodora Jane Herlina Argantari Basuki Herman Herman Herman Hikmawan, Baso Didik Ibrahim, Arsyik Indriyanti, Niken Islamudin Ahmad Islamudin Ahmad Junaidin Junaidin Junaidin, Junaidin Karisman Karisman Khotimah, Ika Kurniawan, Ridho Setya Laode Rijai M. Arifuddin M. Arifuddin M. Arifuddin, M. Meysi, Amelia Michael Rendy Yakubus Mohd Azlan Nafiah, Mohd Azlan Muhammad Faisal Muhammad Faisal Muhammad Yusuf Mus, Nurul Muhlisa Mutiara, Nur Adinda Muzaqi, Muhammad Choirul Nabilah, Cindy Niken Indriyanti Payuk, Seprianto Prabowo, Wisnu Cahyo Prasetya, Fajar Priastomo, Mukti Purba, Gmelina Adelia Putri Putra, Mitosie Gunarsa Caesar Putri Maharani Putri, Nur Arinda Rachmawati, Nova Sri Rahma, Saina Cintami Abdila Rahman, Muhammad Alif Rajo, Nur Wulan Mas Ramlin Rezekilah Rezekilah Ridhotulloh, Yusuf Isro Rija'i, Hifdzur Rashif Rijai, Hifdzur Rashif Rija’i, Hifdzur Rashif Riki RIKI RIKI, RIKI Rolan Rusli Rombe, Irene Aliet Rusli, Rolan Rusman, Arman Salam, Supriatno Salsabila, Syifa Kamila Salsabila, Unik Hanifah Sari, Mila Kansia Setyowati, Widiastuti Agustina Eko Siti Kusmardiyani Sudarma, Mahatma Setya Sulistyarini, Riski Suparningtyas, Juniza Firdha Supriatno Supriatno Salam Syam, Mawar Inrian Vita Olivia Siregar Wahyuda, Aji Arda Nur WISNU PRABOWO Wulandari, Tiara Sahfitri Yotam, Yotam