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All Journal Majalah Obat Tradisional Nagari Law Review Majalah Kedokteran Andalas Journal of Educational Sciences Jurnal Pengabdian Masyarakat Bangsa
Oktavia, Sri
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Cytotoxic Activity of Ethanol Extract of Piper aduncum L. on T47D Breast Cancer Cell Line using the MTT Method Bellatasie, Rezlie; Oktavia, Sri; Rakhmil, Hanaya Fathiha; Uyun, Hendri Satria Kamal
Majalah Obat Tradisional Vol 29, No 3 (2024)
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/mot.88745

Abstract

Cancer treatment is known to cause side effects ranging from mild to severe, which can also affect the quality of the patient's health. Natural ingredients are an alternative source of cytotoxic substances with good anticancer activity and minimum side effects. Sirih hutan (Piper aduncum L.), also known as spiked pepper, is a medicinal plant with potential cytotoxic activity. This study aims to determine the cytotoxic activity of the ethanol extract of P. aduncum L. leaves with the Microculture Tetrazolium Test method. Phytochemical screening showed that P. aduncum L. contains alkaloids, flavonoids, saponin, phenol, and steroid/terpenoid compounds. The cytotoxic activity test was carried out on T47D cells with a concentration of 100 µg/mL, 10 µg/mL, 1 µg/mL, and 0.1 µg/mL test solution. The obtained IC50 value of the ethanol extract of P. aduncum L. was 171.2 µg/mL, belonging to the moderate toxic category. From this study, it is concluded that P. aduncum L holds potential as an anticancer agent.
Analysis of The Level of 21st Century Skills in Productive Teachers at SMK Negeri 2 Padang Panjang Oktavia, Sri; Alfiriani, Adlia; Samudra, Ami Angggraini
Journal of Educational Sciences Vol 8. No. 1. January 2024
Publisher : FKIP-Universitas Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31258/jes.8.1.p.140-150

Abstract

In this 21st century, there are special skills that must be mastered by teachers, especially productive teachers, namely 21st century skills. This study aims to determine the level of 21st century skills possessed by productive teachers at SMK Negeri 2 Padang Panjang. The research method used is quantitative with survey research design. The study population was all teachers at SMK Negeri 2 Padang Panjang, and the sample was taken using purposive sampling technique so that the number of respondents was 26 people. Data analysis was carried out descriptively using index numbers. The research results of this study are the 21st century skill level of productive teachers at SMK Negeri 2 Padang Panjang is classified as in the high category, as evidenced by the high index scores obtained for life and career skills, learning and innovation skills, as well as information, media and technology skills. Based on the research results, productive teachers at SMK Negeri 2 Padang Panjang have a good understanding of the importance of applying 21st century skills in the learning process, as evidenced by the high index value obtained. However, there are several indicators of 21st century skills that are still below the average index value.
Analysis of The Level of 21st Century Skills in Productive Teachers at SMK Negeri 2 Padang Panjang Oktavia, Sri; Alfiriani, Adlia; Samudra, Ami Angggraini
Journal of Educational Sciences Vol. 8 No. 1 (2024): Journal of Educational Sciences
Publisher : FKIP - Universitas Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31258/jes.8.1.p.140-150

Abstract

In this 21st century, there are special skills that must be mastered by teachers, especially productive teachers, namely 21st century skills. This study aims to determine the level of 21st century skills possessed by productive teachers at SMK Negeri 2 Padang Panjang. The research method used is quantitative with survey research design. The study population was all teachers at SMK Negeri 2 Padang Panjang, and the sample was taken using purposive sampling technique so that the number of respondents was 26 people. Data analysis was carried out descriptively using index numbers. The research results of this study are the 21st century skill level of productive teachers at SMK Negeri 2 Padang Panjang is classified as in the high category, as evidenced by the high index scores obtained for life and career skills, learning and innovation skills, as well as information, media and technology skills. Based on the research results, productive teachers at SMK Negeri 2 Padang Panjang have a good understanding of the importance of applying 21st century skills in the learning process, as evidenced by the high index value obtained. However, there are several indicators of 21st century skills that are still below the average index value.
Pelatihan Pembuatan Teh Stevia dan Manfaatnya Sebagai Pemanis alami Uyun, Hendri Satria Kamal; Fajrina, Anzharni; Wiliantari, Selvia; Makmur, Indra; Oktavia, Sri; Bellatasie, Rezlie; Sari, Yeni Novita; Kardela, Widya; Octavia, Maria Dona
Jurnal Pengabdian Masyarakat Bangsa Vol. 3 No. 3 (2025): Mei
Publisher : Amirul Bangun Bangsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59837/jpmba.v3i3.2278

Abstract

Pelatihan pembuatan teh stevia  (Stevia rebaudiana) ini bertujuan untuk memberikan pengetahuan kepada masyarakat dalam memanfaatkan bahan-bahan alami sebagai solusi pemanis alami  untuk mencegah diabetes dan meningkatkan kesehatan secara umum. Pelatihan ini melibatkan 29 peserta yang diajarkan untuk menyiapkan teh stevia  menggunakan metode sederhana. Selain memberikan keterampilan teknis, kegiatan ini juga melibatkan uji hedonik untuk menilai penerimaan produk yang dihasilkan oleh peserta. Uji hedonik dilakukan dengan menilai aspek rasa, bau, warna, dan tekstur minuman yang dihasilkan. Hasilnya menunjukkan respons positif di semua parameter, dengan mayoritas peserta menyatakan preferensi mereka terhadap produk ini.
Time and Concentration-dependent Cytotoxicity of Piperine on Hela Cells Oktavia, Sri; Amir, Arni; Wahyuni, Fatma Sri; Hasmiwati, Hasmiwati
Majalah Kedokteran Andalas Vol. 48 No. 3 (2025): MKA July 2025
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/mka.v48.i3.p288-293.2025

Abstract

Piperine, the primary alkaloid of Piper nigrum and Piper longum, is believed to have anticancer properties. Although research on cervical cancer is still in its early stages, piperine's anticancer capabilities have been established in numerous types of cancer and have been shown to target pathways involved in the cell cycle and apoptosis. This study aims to determine how piperine administration time and concentration affect the viability of Hela cells. The MTT method was used to conduct this study. The concentration of piperine utilized was 1,000; 500; 250; 125, and 62.5 µg/mL, and it was administered for 24 and 48 hours. The IC50 values, obtained after incubation for 24 and 48 hours, were 711.21 µg/mL and 419.75 µg/mL, respectively. We may conclude that the viability of HeLa cells is influenced by piperine in a time- and concentration-dependent manner (p<0.05).
Penerapan Smart Contract dalam Industri Konstruksi di Indonesia: Potensi dan Tantangan Hukum Valentino, Christianto Youstra; Azheri, Busyra; Oktavia, Sri
Nagari Law Review Vol 7 No 1 (2023): Nagari Law Review
Publisher : Faculty of Law, Andalas University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/nalrev.v.7.i.1.p.59-78.2023

Abstract

Technological advancements in Indonesia's Construction have initiated a digital transformation in the sector. The necessity of incorporating automated systems in contract performance to meet future digital needs has become increasingly apparent. This paper presents to spearhead research into the possibility of the Indonesian construction industry adopting smart contracts. The chosen research approach is a qualitative scientific methodology involving a systematic review highlighting the benefits and obstacles associated with adopting smart contracts within the construction industry. Further data were collected from construction contract management experts through interview sessions. The findings reveal that the self-execution feature of smart contracts could better distribute risks within a contract. However, the study also uncovers substantial challenges in applying smart contracts, such as their immutability, irreversibility, and vulnerability to human errors. The study concludes that smart contracts are best suited for short-term contracts that do not require variations. Smart contracts could streamline contract management, reducing time and effectively addressing conflicts and disputes during the contract's lifespan. The devised implementation framework holds significance for construction professionals, particularly those involved in contract administration. Incorporating smart contracts into construction could enhance contract administration and management discipline by fostering investment in this emerging technology
Co-Authors Adlia Alfiriani Anzharni Fajrina Arni Amir Bellatasie, Rezlie Busyra Azheri Fatma Sri Wahyuni Hasmiwati Makmur, Indra Maria Dona Octavia Rakhmil, Hanaya Fathiha Samudra, Ami Angggraini Sari, Yeni Novita Uyun, Hendri Satria Kamal Valentino, Christianto Youstra Widya Kardela Wiliantari, Selvia