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All Journal Jurnal Ilmu Kefarmasian Indonesia SULUH: Jurnal Abdimas
KARTININGSIH, KARTININGSIH
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Biochemistry, Genetics & Molecular Biology Education Health Professions Library & Information Science Medicine & Pharmacology Public Health Other

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Peningkatan Kesehatan Lingkungan Posdaya Masyarakat Jakarta Selatan Melalui Pembuatan Hand Sanitizer Dari Eco-Enzyme Zaidan, Sarah; Yantih, Novi; Kartiningsih, Kartiningsih; Setiyawan, Dessi; Permadi, Trisna
SULUH: Jurnal Abdimas Vol 5 No 1 (2023): SULUH: Jurnal Abdimas Agustus
Publisher : FEB-UP Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35814/suluh.v5i1.3966

Abstract

Hand sanitizer di saat pandemik ini menjadi primadona sehingga bahan-bahannya menjadi langka dan harganya melonjak berlipat-lipat, hal ini menyebabkan masyarakat melakukan pembuatan hand sanitizer sendiri, namun seringkali masayarakat menggunakan bahan-bahan yang berdampak buruk pada Kesehatan. Enzim dari “sampah” ini adalah salah satu cara manajemen sampah yang memanfaatkan sisa-sisa dapur untuk sesuatu yang sangat bermanfaat, dengan demikian sangat logis bila eco-enzyme ini disebut dengan istilah “cairan ajaib”. .Pengabdian Kepada Masyarakat (PKM) dengan program kemitraan masyarakat ini berupa kegiatan dalam bentuk edukasi, pelatihan, dan pendampingan pengolahan sampah organik menjadi cairan eco-enzyme sebagai bahan hand sanitizer pada POSDAYA SOKA yang beralamat Jalan Bungur 2 Kp. Duku., RT. 02/12 Kelurahan Kebayoran Lama Selatan, Kecamatan Kebayoran Lama Jakarta Selatan. Hasil kegiatan, anggota POSDAYA SOKA dapat mengelola dan memanfaatkan sampah organik menjadi cairan eco-enzyme untuk bahan hand sanitizer, sehingga terjadi peningkatan kemandirian kesehatan anggota POSDAYA melalui penggunaan hand sanitizer hasil swadaya masyarakat
Formulation of facial liquid soap wıth 4-(Dimethylamino) chalcone and virgin coconut oil as antibacterial agents against acne-causing bacteria Wulandari, Putri; Mumpuni, Esti; Mulatsari, Esti; Kartiningsih, Kartiningsih
JURNAL ILMU KEFARMASIAN INDONESIA Vol 23 No 2 (2025): JIFI
Publisher : Faculty of Pharmacy, Universitas Pancasila

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35814/jifi.v23i2.1653

Abstract

Acne vulgaris is a multifactorial skin disorder commonly associated with infections caused by Staphylococcus epidermidis and Cutibacterium acnes. This study aimed to develop and evaluate an antibacterial facial liquid soap containing 4-(Dimethylamino) chalcone and virgin coconut oil (VCO). The synthesized chalcone, a flavonoid derivative obtained through the Claisen–Schmidt condensation reaction, was characterized using TLC, melting point analysis, UV-Vis spectrophotometry, and LC-MS/MS. Formulations containing 1.25% and 2.5% chalcone combined with 40% VCO were prepared and tested. Antibacterial activity was evaluated using the agar diffusion method, while physical properties were assessed through organoleptic observation, homogeneity, foaming ability, pH measurement, stability testing, and skin irritation tests. The 1.25% chalcone formulation demonstrated strong antibacterial activity, producing inhibition zones of 19.40±0.39 mm against C. acnes and 18.97±0.45 mm against S. epidermidis. All formulations were stable, homogeneous, and non-irritating. These findings indicate a synergistic antibacterial effect between chalcone and VCO, supporting their potential use as natural active ingredients in anti-acne facial soap formulations.
Co-Authors Esti Mumpuni, Esti Mulatsari, Esti Novi Yantih PUTRI WULANDARI Setiyawan, Dessi Trisna Permadi Zaidan, Sarah