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Pengaruh Jenis Fluor Topikal Terhadap Kebocoran Mikro pada Pit and Fissure Sealant Hudiyati, Maya; Chairani, Shanty; Rais, Sri Wahyuningsih
Jurnal Material Kedokteran Gigi Vol 5 No 1 (2016): JMKG Vol 5 No 1 Maret 2016
Publisher : Ikatan Peminat Ilmu Material dan Alat Kedokteran Gigi (IPAMAGI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (308.089 KB)

Abstract

Prevention of dental caries in children can be done with topical fluoride as well as pit and fissure sealant. Topical fluoride application followed by pit and fissure sealant is still controversial because it allegedly could impair the bond between pit and fissure sealant materials to the teeth, so that it can lead to microleakage. The aim of this study was to determine the effect of 5% NaF and 1.23% APF on microleakage of RMGIC and flowable composite as pit and fissure sealant materials. Thirty extracted premolars were prepared and then divided into three groups: without topical fluoride, with application of 5% NaF (Enamelast, USA), and with application of 1.23% APF (60 Second Taste, USA); then filled using RMGIC (GC Fuji II LC, Japan) and flowable composite (Esthet.Xflow, USA). The teeth were soaked in methylene blue and then cut buccolingually. Microleakage was observed using stereomicroscope and scored in an ordinal scale. The Kruskal-Wallis test on RMGIC groups was not significant, while in the flowable composite groups was significant (p <0.05). Mann-Whitney test showed a significant difference between the RMGIC and flowable composite groups after application of 1.23% APF. It can be concluded that microleakage of pit and fissure sealant using a flowable composite was higher than RMGIC after application of 1.23% APF.
Ginger And Citrus Aromatherapy For Servical Cancer Patients Post Chemotherapy Adhisty, Karolin; Rizona, Firnaliza; Hudiyati, Maya
Jurnal Aisyah : Jurnal Ilmu Kesehatan Vol 6 (2021): Special Issue GINC
Publisher : Universitas Aisyah Pringsewu

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1330.446 KB) | DOI: 10.30604/jika.v6iS1.760

Abstract

Nausea and vomiting after chemotherapy is one of the effects that can reduce the patient'sspiritual biopsychosocial factor. The first purpose of this study was to determine the effect of aromatherapy inhalation in ginger and citrus. The second one to compare the value of both citrus and ginger aromatherapy to reduce effect of nausea and vomiting. This research was an experimental study with four solomon group designs. A sample of 68 respondents were divided into four groups by purposive sampling. Ginger aromatherapy showed p 0.002 less than alpha 0.05 and citrus aromatherapy showed p 0.009 less than alpha 0.05. These results indicate that both aromatherapy can reduce nausea and vomiting.The second analysis used the Mann-Whitney statistical test to compare the effect on the intervention group of each inhalation aromatherapy. The results showed that the p-value (0.192) more than alpha (0.05), which means that statistically there is no difference in the average score of nausea and vomiting between the intervention groups of ginger aromatherapy and citrus aromatherapy, but ginger aromatherapy can reduce nausea and vomiting by a difference mean 3.18 greater than citrus aromatherapy. Nurses can use ginger and citrus aromatherapy as an alternative solution to reduce nausea and vomiting in improving the patient's physical condition. 
THE EFFECT OF EXTRACTS OF CURCUMA ZEDOARIA ON THE EXPRESSION OF THE PROINFLAMMATORY CYTOKINE TNF-α Mozartha, Martha; Hudiyati, Maya; Anastasia, Danica
International Journal of Islamic and Complementary Medicine Vol. 3 No. 1 (2022): International Journal of Islamic and Complementary Medicine
Publisher : International Islamic Medicine Forum

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55116/IJICM.V3I1.31

Abstract

Curcuma zedoaria is known to have antibacterial and antifungal activity, and have the potential to be used as an irrigation solution in endodontic treatment. Endodontic irrigant that is going to be used clinically has to go through a series of research, to ensure effectiveness and safety without adverse side effects. The purpose of this study was to determine the effect of extracts of C. zedoaria with concentrations of 5%, 10%, and 20% as endodontic irrigation on the expression of the proinflammatory cytokine TNF-α on Wistar rat. This experimental study used extracts of C.zedoaria with concentrations of 5%, 10%, 20%, as tested groups, 5.25% sodium hypochlorite as the positive control, and saline solution as a negative control group. Thirty male adult Wistar rats (Rattus novergicus) with an average weight of 150-200 g were included in this study. The dermis of each rat was marked with a circle and 0.1 ml of each irrigant was injected subcutaneously by using a syringe. The evaluation was made 14 days after injection. The expression of cytokine TNF-α was assessed with the IHC method. The percentage of TNF-α expression was evaluated and analyzed by using One-way Anova followed by Tukey Post Hoc test. The results of this study revealed that the highest percentage of TNF-α expression is positive control group (5.25% NaOCl). Furthermore, the higher the concentration of C. zedoaria extract, the greater the percentage of TNF-α expression. One-way Anova results showed that there was a significant difference between groups (p ≤ 0.05). From the results of the Tukey test, it was found there was a significant difference between groups except between the negative control group and the 5% extract group. It can be concluded that C. zedoaria extract 10 and 20% can increase TNF-α expression, but its ability is lower than sodium hypochlorite.