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Purnamasari, Vina
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PROFIL PENGKAJIAN RESEP OBAT HIPERTENSI DI INSTALASI FARMASI RUMAH SAKIT X SULAWESI SELATAN Aztriana, Aztriana; Nurlina, Nurlina; Anriani, Anriani; Purnamasari, Vina
Jurnal Kesehatan Tambusai Vol. 5 No. 4 (2024): DESEMBER 2024
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jkt.v5i4.32297

Abstract

Hipertensi merupakan penyakit yang rentan terhadap perubahan pengobatan berulang dan regimen poliobat. Sehingga sangat rentan terhadap ketidaksesuaian dalam pengobatannya salah satu adalah termasuk peresepan. Juga menjadi penyebab utama morbiditas dan mortalitas. Hal ini menandakan bahwa sebagian besar kasus hipertensi di masyarakat belum terdiagnosis dan terjangkau pelayanan kesehatannya. Sehingga sangat pentingnya dilakukan pengkajian resep obat antihipertensi. Penelitian ini bertujuan untuk mengetahui kesesuaian resep obat antihipertensi meliputi pengkajian administrasi, pengkajian farmasetik, dan pengkajian klinis pada pasien rawat jalan pada bulan oktober hingga desember 2023 di intalasi farmasi Rumah Sakit X Sulawesi Selatan. Metode pada penelitian ini bersifat deskriptif dengan jenis penelitian adalah retrospektif. Dari penelitian ini diperoleh hasil bahwa terdapat 872 lembar resep yang mengandung obat antihipertensi. Hasil pengkajian administrasi memperoleh hasil bahwa 100% resep mencantumkan semua aspek administrasi. Pada pengkajian farmasetik diperoleh hasil bahwa 100% resep menuliskan bentuk sediaan, kekuatan sediaan, dan aturan pakai obat diperoleh hasil 3,38%. Dengan mayoritas obat antihipertensi yang diresepkan dalam bentuk sediaan tablet. Pada peengkajian klinis diperoleh hasil bahwa terdapat kesesuaian dosis tepat 96,61% dan terdapat 48,96% resep yang memiliki interaksi antara obat antihipertensi dan obat lainnya serta tidak terdapat duplikasi. Hasil penelitian ini menampilkan belum sepenuhnya sesuai antara profil pengkajian resep obat antihipertensi di Rumah Sakit X Sulawesi Selatan dengan Permenkes No. 72 tahun 2016.
STUDI INKOMPATIBILITAS DAN INSTABILITAS SEDIAAN EXTEMPORANEOUS PULVERES VITAMIN C DARI RUMAH SAKIT IBU DAN ANAK MASYITA MAKASSAR Mursyid, A. Mumtihanah; Purnamasari, Vina; Syam, Adinda
Jurnal Kesehatan Tambusai Vol. 5 No. 3 (2024): SEPTEMBER 2024
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jkt.v5i3.33038

Abstract

Pelayanan kefarmasiaan di rumah sakit bertujuan meningkatkan kualitas hidup pasien melalui layanan farmasi yang bertanggung jawab, mencakup informasi, edukasi, serta monitoring penggunaan obat oleh apoteker, termasuk obat racikan. Obat racikan Extemporaneous pulveres sering digunakan untuk pasien anak yang kesulitan menelan tablet atau kapsul, namun memiliki risiko inkompatibilitas dan instabilitas yang dapat mempengaruhi efektivitas dan keamanan obat. Penelitian ini dilakukan di Rumah Sakit Ibu dan Anak Masyita di Makassar untuk mempelajari profil inkompatibilitas dan Instabilitas sediaan Extemporaneous Pulveres Vitamin C melalui observasi fisik dan analisis kadar. Metode yang digunakan adalah pengamatan perubahan fisik dan analisis kadar vitamin C pada sediaan racikan di rumah sakit tersebut. Hasil penelitian menunjukkan adanya potensi Inkompatibilitas dan Instabilitas pada sediaan racikan Vitamin C, terutama karena fotolisis yang menyebabkan degradasi. Kesimpulan dari penelitian ini adalah pentingnya perhatian lebih terhadap stabilitas dan kompatibilitas sediaan Extemporaneous Pulveres untuk memastikan efektivitas dan keamanan obat. Penelitian ini diharapkan memberikan manfaat teoritis sebagai sumber data ilmiah dan manfaat praktis bagi apoteker dalam mengevaluasi sediaan Extemporaneous yang mereka racik.
Skrining Fitokimia Ekstrak Daun Mimba (Azadirachta indica Juss) dan Kemangi (Ocimum sanctum L.) dan Evaluasinya Sebagai Hair Tonic Spray Irwan, Andi Annisa Anastasya; Dzakiyah, Ainun; Angriani, Yuni; Asri, Fitriani; Khalid, Davi Rahmat; Purnamasari, Vina; Yuliana, Dewi
Jurnal Fitofarmaka Indonesia Vol 11, No 2 (2024): JURNAL FITOFARMAKA INDONESIA
Publisher : Faculty of Pharmacy, Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/jffi.v11i2.1287

Abstract

A phytochemical screening of Neem (Azadirachta indica Juss) and Holy Basil (Ocimum sanctum L) leaf extracts has been conducted, along with a hair tonic spray formulation. The aim of this research is to determine the chemical constituents of Neem and Holy Basil leaf extracts and formulate them into a hair tonic spray. The study included tests for flavonoids, tannins, alkaloids, steroids, and saponins in both Neem and Holy Basil extracts, as well as an evaluation of the stability of the hair tonic spray formulation. The research findings revealed that the Neem and Holy Basil extracts contain flavonoids, tannins, alkaloids, steroids, and saponins. The formulation was evaluated through organoleptic assessments, homogeneity tests, pH measurements, bulk density, and viscosity assessments, all of which Evaluation met the requirements established for a hair tonic spray.
PROFIL PENGELOLAAN OBAT DI INSTALASI FARMASI RUMAH SAKIT UMUM DAERAH (RSUD) TENRIAWARU KABUPATEN BONE SULAWESI SELATAN Astriana; Mirawati; Purnamasari, Vina; Aurora, Amanda Raisya
Jurnal Kesehatan Tambusai Vol. 5 No. 3 (2024): SEPTEMBER 2024
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Pengelolaan obat merupakan suatu kegiatan yang menjamin ketersediaan dan keterjangkauan obat yang efektif, efisien dan rasional secara optimal untuk mencapai ketepatan jumlah dan jenis persediaan farmasi dengan memanfaatkan sumber yang ada seperti tenaga, dana, sarana dan perangkat lunak. Kegiatan pengelolaan obat menyangkut segala aspek yaitu pemilihan, perencanaan kebutuhan, pengadaan, penerimaan, penyimpanan, pendistribusian, penarikan dan pemusnahan, pengendalian, dan administrasi. Tujuan dari penelitian ini adalah untuk mengetahui dan menyajikan data tentang pengelolaan obat di Instalasi Farmasi Rumah Sakit Umum Daerah Tenriawaru Kabupaten Bone Sulawesi Selatan. Penelitian ini dilakukan dengan menggunakan metode kualitatif dan kuantitatif secara deskriptif. Dari hasil penelitian diketahui bahwa profil pengelolaan obat di Instalasi Farmasi Rumah Sakit Umum Daerah (RSUD) Tenriawaru Bone pada aspek pemilihan, perencanaan kebutuhan, pengadaan, penerimaan, pendistribusian, pemusnahan dan penarikan, pengendalian, dan administrasi telah sesuai dengan regulasi terstandar di Indonesia dengan persentase kesesuaian mencapai 100% dan termasuk dalam kriteria Sangat Baik, sedangkan pada aspek Penyimpanan hanya mencapai persentase kesesuaian 98,36% dan termasuk dalam kriteria Sangat Baik. Kesimpulan pengelolaan obat di Instalasi Farmasi RSUD Tenriawaru Bone belum sepenuhnya sesuai dengan regulasi terstandar di Indonesia yaitu Permenkes Nomor 72 Tahun 2016 Tentang Standar Pelayanan Kefarmasian di Rumah Sakit dan Petunjuk Teknis Standar Pelayanan Kefarmasian di Rumah Sakit Tahun 2019.
Gambaran Penyimpanan Obat di Rumah Sakit Umum Daerah Hajjah Andi Depu Kabupaten Polewali Mandar Dini Nurdwiyanti, Puspa; Mursyid, A.Mumtihanah; Purnamasari, Vina
Makassar Pharmaceutical Science Journal (MPSJ) Vol 1 No 4 (2024)
Publisher : PHARMACY UMI JOURNAL SYSTEM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/mpsj.v1i4.107

Abstract

Drug storage is an important stage in the drug management because proper drug storage can maintain drug quality, prevent irresponsible drug use, prevent theft and facilitate drug search and control in hospitals. The impact of the storage process that is not in accordance with pharmaceutical requirements is that the availability of drugs is not maintained and there is the potential for irresponsible drug use resulting in losses for the Hospital. The purpose of this study was to find out an overview of drug storage at the Hajjah Andi Depu General Hospital, Polewali Mandar Regency. This study used a descriptive method by comparing observational data, interviews and document searches with the Minister of Health Regulation Number 72 of 2016, Guidelines for Pharmaceutical Supplies Management in Hospitals 2010, and Technical Guidelines for Pharmaceutical Service Standards in Hospitals 2019. The data obtained will be calculated based on the guttman scale, then calculate the percentage value of compliance with the regulations. Based on the results of the study it can be seen that the drug storage process at the Hajjah Andi Depu Regional General Hospital, Polewali Mandar Regency, is in the very good category with the acquisition of a conformity percentage value of 82.76%.
Gambaran Pengelolaan Obat Di Instalasi Farmasi Rsud Provinsi Sulawesi Barat riady, ninda thiara; Nurlina, Nurlina; Purnamasari, Vina
Makassar Pharmaceutical Science Journal (MPSJ) Vol 2 No 1 (2024)
Publisher : PHARMACY UMI JOURNAL SYSTEM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/mpsj.v2i1.144

Abstract

Hospital Pharmacy Installation (IFRS) is a functional implementing unit organizes all pharmaceutical service activities in hospitals, which functions to carry out the management of pharmaceutical supplies with the stages of selecting, planning, procuring, storing, distributing, controlling, deleting, recording and reporting. This study aims to determine the stages of management of pharmaceutical supplies in West Sulawesi Provincial Hospital using descriptive qualitative research through interviews and observation (observation). In this study guided interviews that have been arranged systematically using a check list. The results of this study reveal that the management of pharmaceutical preparations in the Pharmacy Installation of the West Sulawesi Provincial Hospital has been effective and efficient from several aspects of management which shows a percentage of 80-100%. However, the procurement and storage aspect are still inefficient because the expenditure has not gone through the e-catalog and there is no fire extinguisher. The drug management system at the Pharmacy Installation of the West Sulawesi Provincial Hospital is in accordance with the Regulation of the Minister of Health of the Republic of Indonesia No. 72 of 2016 and Technical Guidelines for Pharmaceutical Standards in Hospitals in 2019.
Profil Penggunaan Obat Antihipertensi Pada Pasien Rawat Inap di RSUD La Temmamala Kabupaten Soppeng Nugraha, Akram Resa; Herman, Hendra; Purnamasari, Vina
Makassar Pharmaceutical Science Journal (MPSJ) Vol 2 No 1 (2024)
Publisher : PHARMACY UMI JOURNAL SYSTEM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/mpsj.v2i1.178

Abstract

Hypertension has become one of the deadly diseases in both Indonesia and the world. Hypertension (or high blood pressure) is defined as a condition when the blood pressure is above 140/90 mmHg. According to the profile of the Health Department of South Sulawesi Province in 2018, Soppeng Regency has the highest rate of people with hypertension at 98,79% with 4.997 from 5.058 patients. The purpose of this research is to describe the usage of anti-hypertension medicines to the patients at Latemmalala Regional Public Hospital, Soppeng Regency, in the period between June-December 2022. This research is considered a quantitative research with the descriptive method and observational research design, as well as the retrospective approach that begins with the documentary research taken from the patient’s medical records. The result shows that the characteristic rate of the patients according to the gender is mostly found on females, with 20 patients being confirmed (67,5%), for the ages between 60-69 years old, 15 patients are confirmed (46,9%), and the following disease that is also found on the patients with hypertension is the kidney failure, where there are 14 patients being confirmed (20%). The most used type of medicine is the calcium channel blocker (CCB), another medicine that is also often used is the 57 units of amlodiphine (37,5%), and the most-used combined medicines are 9 units of amlodiphine and furosemid (39,1%). According to the accuracy and the inaccuracy of the medical usage, the accuracy is 100% and the inaccuracy is 0%.
A LITERATUR REVIEW : AKTIVITAS IMUNOMODULATOR PADA TANAMAN HERBAL Yuliana, Dewi; Handayani, Dian Pratiwi; Purnamasari, Vina
Makassar Pharmaceutical Science Journal (MPSJ) Vol 1 No 4 (2024)
Publisher : PHARMACY UMI JOURNAL SYSTEM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/mpsj.v1i4.230

Abstract

Health problems that often occur in Indonesia are problems related to diseases caused by free radicals. The presence of free radicals can trigger damage to cells and can disrupt the body's immune system. The immune system can be enhanced or suppressed, one way is by administering immunomodulators. Several natural compounds have the ability to increase immune system activity, including flavonoids, curcumin, limonoids, vitamin C, vitamin E and catechins. Phenolic components such as flavonoids and polyphenols can improve the immune system by increasing Interleukin-12 (IL-12) and lymphocyte proliferation. Based on the many health problems that arise in Indonesia due to the presence of free radicals, the aim of the research is to conduct a literature review on the mechanism of action of herbal plants as immunomodulators and the methods used to determine the mechanism of action of natural immunomodulators. The method used to review this article is to carry out an online search process using several search engines such as PubMed, Scopus, ProQuest and Schoolar. Based on reference studies, several herbal plant extracts act as immunomodulators with different activities such as increasing the activity of Immunoglobulin M (IgM), reducing the number of leukocytes, stimulating the body's immunity with flavonoid content and increasing the ability of phagocytosis.
Co-Authors A. Mumtihanah Mursyid, A. Mumtihanah Angriani, Yuni Anriani, Anriani Asri, Fitriani Astriana Aurora, Amanda Raisya Aztriana Aztriana, Aztriana Dewi Yuliana Dini Nurdwiyanti, Puspa Dzakiyah, Ainun Handayani, Dian Pratiwi Irwan, Andi Annisa Anastasya Khalid, Davi Rahmat Mirawati Mursyid, A.Mumtihanah Nugraha, Akram Resa Nurlina Nurlina riady, ninda thiara Syam, Adinda