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All Journal International Journal of Public Health Science (IJPHS) Indonesian Journal of Pharmaceutical Science and Technology Journal of Islamic Pharmacy JSFK (Jurnal Sains Farmasi & Klinis) Manuju : Malahayati Nursing Journal Jurnal Kesehatan Jurnal Ilmiah Medicamento MAHESA : Malahayati Health Student Journal Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Pharmaceutical Sciences and Research (PSR) Journal of Public Health and Pharmacy Jurnal Kefarmasian Indonesia Jurnal Kesehatan
Setiadi, Adji Prayitno
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Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health

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Pharmacy Student Recommendations on Self-Medication for Headaches: A Cross-Sectional Study in Surabaya Halim, Steven Victoria; Pratama, Jeffry Refananto; Karinda, Itsna Laudzy; Setiadi, Adji Prayitno; Aditama, Lisa; Wibowo, Yosi Irawati; Brata, Cecilia; Setiawan, Eko
Indonesian Journal of Pharmaceutical Science and Technology Vol 12, No 2 (2025)
Publisher : Indonesian Journal of Pharmaceutical Science and Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/ijpst.v12i2.53546

Abstract

Assessing students’ ability to provide appropriate recommendations for self-medication requests is key in developing course materials for future pharmacists. Until recently, the number of published articles evaluating the appropriateness of recommendation provided by pharmacy students towards headache cases, as one of the most common symptoms urging people to seek advice from professional healthcare, is still limited. This observational study with cross-sectional design aims to identify the type and appropriateness of recommendation given by pharmacy professional degree students on two types of headache cases, i.e., tension type headache and migraine due to adverse drug reaction (ADR). The students characteristic data, type, and recommendation appropriateness were analyzed descriptively. In total, 86 students were involved in this research (response rate 82.7%) with different recommendation profiles for two different headache cases. The majority of the participants recommended a pharmaceutical product for tension type headache while referral to physicians was advised for migraine due to ADR. The appropriateness analysis findings revealed that students gave more appropriate recommendations for tension type headache (89.5%) compared to migraine due to ADR (77.9%) case. Therefore, students’ ability to provide relevant recommendations for headaches due to ADR requires further improvement by giving some cases accordingly during the learning process.
Observasi Klinis Penggunaan Probiotik sebagai Terapi Pendukung pada Pasien dengan Kolitis Ulseratif dan Limfoma Non-Hodgkin Geson, Ge Recta; Kiranawati, Titi Mutiara; Putra, Galih Satrio; Setiadi, Adji Prayitno
Journal of Islamic Pharmacy Vol 10, No 2 (2025): J. Islamic Pharm.
Publisher : Universitas Islam Negeri Maulana Malik Ibrahim Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18860/jip.v10i2.36720

Abstract

Kolitis ulseratif merupakan penyakit inflamasi usus kronis yang memerlukan terapi jangka panjang dan pada kondisi tertentu dapat disertai komorbiditas keganasan, seperti Non-Hodgkin’s Lymphoma (NHL). Penatalaksanaan kondisi ini sering kali melibatkan terapi komprehensif yang berpotensi mempengaruhi kondisi gastrointestinal pasien dengan golden standard therapy yang dikenal sebagai R-CHOP. Studi kasus ini menyajikan observasi klinis terhadap satu pasien dengan kolitis ulseratif dengan NHL yang mendapatkan R-CHOP dan suplementasi probiotik multistain sebagai terapi pendukung selama masa perawatan. Data diperoleh dari rekam medis dan observasi klinis secara deskriptif tanpa analisis statistik. Selama periode observasi, pasien menunjukkan perbaikan kondisi klinis secara umum dan tidak mengalami perburukan gejala gastrointestinal yang bermakna setelah pemberian adjuvant therapy berupa probiotik multistain jika dibandingkan dengan sebelum pemberian probiotik multistain. Kombinasi standard kemoterapi R-CHOP pada kasus ini dengan suplementasi probiotik multistrain berpotensi menghambat progresi keganasan sel kanker NHL. Pemberian probiotik multistain dapat memberikan manfaat terapeutik dengan meningkatkan apoptosis pada sel kanker sekaligus menurunkan peradangan pada kolitis ulseratif berdasarkan hasil gambaran kolonoskopi. Meskipun demikian, temuan ini bersifat deskriptif antara pemberian probiotik dan perbaikan kondisi klinis pasien yang mengalami kolitis ulseratif dengan NHL. Penelitian lanjutan dengan desain yang lebih kuat diperlukan untuk menkonfirmasi potensi peran probiotik mutristrain sebagai terapi pendukung pada kondisi klinis serupa.
KAJIAN PENGGUNAAN MISOPROSTOL ORAL DAN VAGINA SEBAGAI PENGINDUKSI PERSALINAN Setiadi, Adji Prayitno; Wibowo, Yosi Irawati; Anggara, I Gede Yudi; Dhitama, I Made Yogista
Jurnal Kesehatan - STIKes Prima Nusantara Vol 12 No 1 (2021): JURNAL KESEHATAN
Publisher : LPPM Universitas Prima Nusantara Bukittinggi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35730/jk.v12i1.428

Abstract

Latar belakang: Misoprostol telah digunakan secara luas sebagai penginduksi persalinan, walaupun di beberapa negara masih off-label. Oleh karenanya, pembaharuan data terkait misoprostol perlu dilakukan secara berkelanjutan untuk mendukung praktek berbasis bukti.Tujuan: menyediakan kajian profil misoprostol terkait dengan indikasi, efektivitas dan efek sampingnya.Metode: Kajian naratif dengan penelusuran pada PubMed (Medline), CINAHL, dan Science Direct untuk mendapatkan artikel penelitian acak terkontrol terkait misoprostol oral/vaginal sebagai penginduksi persalinan pada periode 1 Januari 2014 sampai 20 Juni 2020.Hasil: Terdapat 9 artikel yang membandingkan misoprostol vaginal (MV) versus misoprostol oral (MO) (atau placebo atau dinoprostone). Misoprostol terutama digunakan sebagai penginduksi persalinan pada kondisi kehamilan post-datism, atau adanya komplikasi maternal/fetal. MV terlihat lebih efektif terkait ‘kejadian persalinan per-vaginam dalam 24 jam’ dibandingkan MO (1 penelitian menunjukkan perbedaan yang signifikan, p<0,001). Sedangkan terkait dengan ‘tingkat operasi sesar’, masih menunjukkan hasil yang bervariasi. Efek samping maternal terkait hiperstimulasi uterus dan takisistole menunjukkan kecenderungan yang lebih tinggi pada MV. Efek samping pada fetus, seperti meconium-stained liquor dan abnormalitas denyut jantung fetus, cenderung lebih tinggi pada MV, di mana masing-masing terdapat 1 penelitian yang menunjukkan perbedaan yang signifikan (p=0,004 dan p=0,047, secara berurutan).Simpulan: Misoprostol vaginal tampak memberikan profil  efektivitas yang lebih baik, namun terdapat kecenderungan risiko efek samping yang lebih tinggi; sehingga, pemberian oral memiliki potensi sebagai alternatif.
General Practitioners’ Perceptions of Collaboration with Pharmacists in Primary Care Settings: A Study Driven by Social Capital Theory and Theory of Planned Behavior Lovarya, Gabby; Wibowo, Yosi Irawati; Setiadi, Adji Prayitno
Jurnal Ilmiah Medicamento Vol 12 No 1 (2026): Jurnal Ilmiah Medicamento (In progress)
Publisher : Fakultas Farmasi Universitas Mahasaraswati Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36733/medicamento.v12i1.11141

Abstract

Background: Pharmacists are expected to take up broader clinical roles and collaborate with general practitioners (GPs); however, data on the perception of GPs’ in the primary care settings is lacking.Objective: This study aimed to explore GPs’ perceptions driven by Theory Planned Behavior (TPB) and Social Capital Theory (SCT) towards collaboration with pharmacists in primary care settings.Methods: Interviews using questionnaires (with a combination of open-and closed-ended questions) were conducted with GPs at all Puskesmas in East Surabaya (n=14). Descriptive analysis was used to summarize data from closed-ended questions, and thematic analysis was used for open-ended questions.Results: A total of 28 GPs of 14 Puskesmas were included (i.e., 2 GPs per Puskesmas). The mean scores of each dimension for intrapersonal perceptions (based on TBP): 1) attitude (2.6 – positive); 2) subjective norms (3.3 – positive), 3) difficulty (2.75 – low). While the mean scores for interpersonal perceptions (based on SCT): 1) level of trust (5.7 – high); 2) level of social capital (6.0 – high). There were five themes for basic trusts: i) daily performance, ii) pharmacy skills and knowledge, iii) work experience, iv) performance track records, v) ability to communicate and collaborate with GPs. This study highlighted while GPs generally have positive perceptions, some items warrant considerations, such as negative experience with pharmacists (39.3%), lack of support from management (92.9%), and perceived difficulty to practice collaboration due to workload, cost and facilities. Additionally, 42.9% of GPs reported that they cannot fully trust delegating work to pharmacists.Conclusions: Findings from this study should provide guidance to develop strategies to optimize collaborative practice with GPs, thus facilitating the expanded clinical roles of pharmacists in primary care settings.
The Multi-Strain Probiotics Effect as Adjuvant Therapy for HIV Patients at Waluyo Jati Regional Hospital, Probolinggo Regency, East Java, Indonesia Harjanti, Luki; Setiadi, Adji Prayitno; Kartika, Nanik Triana
Malahayati Nursing Journal Vol 8, No 5 (2026): Volume 8 Nomor 5 (2026)
Publisher : Universitas Malahayati Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/mnj.v8i5.25035

Abstract

ABSTRACT Human Immunodeficiency Virus (HIV) infection causes Acquired Immune Deficiency Syndrome (AIDS) by attacking immune cells, especially T-helper lymphocytes (CD4). This study aims to determine the benefits of multi-strain probiotics as adjuvant therapy in People Live with HIV (PLHIV) with suppressed viral load at Waluyo Jati Regional Hospital with a primary focus on changes in CD4 levels and Opportunistic Infection. This study was conducted using the Quasi-Experimental Design One Group Pretest Posttest method involving 23 PLHIV at Waluyo Jati Regional Hospital. The sample individuals in this study were PLHIV with a history of suppressed viral load and had received ART (antiretroviral) therapy for at least 2 (two) years. Data collection in this study was carried out for 90 (ninety) days. Based on the Shapiro-Wilk normality test value, it is known that the research data obtained is data with a normal distribution (p 0.05). Based on this study, it was found that the administration of adjuvant therapy in the form of multi-strain probiotics show statistically significant effect on increasing CD4 levels in study participants after three months of treatment. Individually, 82,46 % of patients experienced an increase in CD4, while 17,36 % experienced a decrease in CD4 (p = 0.001; p 0.05). The supplementation of probiotics has a statistically significant effect on increasing CD4 cell levels in HIV patients undergoing antiretroviral (ART) therapy. The overall occurrence of opportunistic infections (OIs) in the study group was low throughout the three months observation period. Only two OI cases were identified, one case of pneumonia and one case of oral candidiasis. Both of which appeared in the first month, with no additional infections detected in the subsequent months. Keyword: HIV, Antiretroviral, Multi-strain Probiotic, CD4, Opportunistic Infections.
Co-Authors Abdul Rahem, Abdul Anggara, I Gede Yudi Bobby Presley, Bobby Brata, Cecilia Dhitama, I Made Yogista Edbert, Sonny Eko Setiawan Galih Satrio Putra Geson, Ge Recta Halim, Steven Victoria Harjanti, Luki I Gusti Agung Ari Kusuma Yana Istiqomah, Reza Amelia Karinda, Itsna Laudzy Kartika, Nanik Triana Lisa Aditama, Lisa Lovarya, Gabby Makkulawu, Andi Marisca Evalina Gondokesumo, Marisca Evalina Ningsih, Linda Fidya Nurul Amalia Octafelia, Yustina Pratama, Jeffry Refananto Putri, Virginia Johanes Ramadanti, Friska Yanuar Santoso, Devina Erawati Sulisetiorini, Sulisetiorini Sunderland, Bruce Susanto, Verlita Evelyn Sutejo, Erwin Sylvi Irawati Titi Mutiara Kiranawati Tri Budi Wahyuni Rahardjo, Tri Budi Wahyuni Wibowo, Yosi Irawati