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All Journal Jurnal Pengabdian kepada Masyarakat Nusantara Jurnal Pengabdian Teknologi Tepat Guna Sciences of Pharmacy Indonesian Journal of Medical and Pharmaceutical Science
Susmayanti, Windi
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Religion Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Engineering Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Medicine & Pharmacology Public Health Social Sciences

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Journal : Indonesian Journal of Medical and Pharmaceutical Science

 1 
Pengaruh Konsentrasi PVA Terhadap Aktivitas Antioksidan Dan Sifat Fisik Masker Gel Peel Off Ekstrak Etanolik Daun Putri Malu (Mimosa pudica L) Krisya, Otta Ganes; Januarti, Ika Buana; Susmayanti, Windi
Indonesian Journal of Medical and Pharmaceutical Science Vol. 2 No. 1 (2023)
Publisher : Sultan Agung Islamic University of Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/ijmps.v2i1.91

Abstract

Background: The leaves of Putri malu (Mimosa pudica L.) contain flavonoid compounds which act as antioxidants to prevent and reduce the effects of free radicals on the skin. The potency of this ingredient is formulated into a peel-off mask with a PVA gel base because it can help penetrate the active substance into the skin by forming a strong and plastic film that provides good contact between the drug and the skin. The purpose of this study was to determine the effect of PVA concentration on the physical properties and antioxidant activity of the Mimosa Pudica L. ethanolic extract peel-off gel mask. Methods: The leaves of Putri malu were extracted by maceration using 70% ethanol and then peel-off mask preparations were made with PVA concentrations of 8%, 10% and 12%. The masks were tested for physical properties including organoleptic tests, pH strength tests, viscosity and dry time tests as well as antioxidant activity. The data obtained was then analyzed using One Way ANOVA and Kruskall Wallis. Results: EEDPM Peel-Off Mask formula 1 produced an IC50 of 5.505 μg/ml, formula 2 1.088 μg/ml and formula 3 0.606 μg/ml which means that the three formulas have strong antioxidant activity. Conclusion: The higher the concentration of PVA in the ekstrak etanolik daun putri malu (EEDPM) peel-off gel mask, the stronger the antioxidant activity.
Pengaruh Waktu Dan Suhu Ekstraksi Daun Melinjo (Gnetum Gnenom L.) terhadap Aktivitas Antioksidan Susmayanti, Windi; Kusumawati, Dwi Endah
Indonesian Journal of Medical and Pharmaceutical Science Vol. 2 No. 2 (2023)
Publisher : Sultan Agung Islamic University of Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/ijmps.v2i2.154

Abstract

Background: The widely cultivated melinjo leaf, or Gentum L genome, is the most valuable commodities cause it contains phenolic chemicals that have antioxidant properties. It is possible to get phenolic chemicals from melinjo leaves by macerating them in ethanol, typically at room temperature. By raising the temperature and length of the extraction process, the yield-maximizing extraction process can be hastened. Methods: The objective of this study is to ascertain the antioxidant activity of melinjo leaves that have been ethanol extracted at 45, 60, and 75 °C. For each temperature change, extraction was done using 96% ethanol (1:10, w/v) for 30 and 45 minutes. The yield, phytochemical assay, total phenolic, and antioxidant activity using the The CUPRAC technique is the variables tested in this study. Results: According to research findings, temperature and extraction time have an impact on yield, content phenolic total, and antioxidant activity. An extract with the maximum antioxidant activity and the consistent phenol content 105.97±5.53 mg GAE/ml and Ic50 of 59.7953 was produced after 45 minutes of extraction at 60°C, but the yield was only 2.22%.
Co-Authors Anjeline, Aprilia Mega Arifa, Sinta Dedi Rusdi Dwi Endah Kusumawati Fathnin, Fildza Huwaina Fauziyah, Afifah Husnun Januarti, Ika Buana Krisya, Otta Ganes Meliana, Dias Feni Nisa, Najwa Afifatun Putri, Devyra Yunika Mutiara Sari Suwarto Rahma, Silfiya Rahmadani, Azmi Rina Wijayanti Saputri, Seftiyaningsih Duwi Shihab, Aura Najwa Ulya, Fadhia Tafrichatul Wulandari, Mukharomah Gita