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All Journal Jurnal Pelayanan dan Pengabdian Masyarakat (Pamas) Media Farmasi Indonesia Indonesian Journal of Medical and Pharmaceutical Science
Januarti, Ika Buana
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Biochemistry, Genetics & Molecular Biology Chemistry Decision Sciences, Operations Research & Management Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Public Health Other

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EKSTRAKSI SENYAWA FLAVONOID DAUN JATI (Tectona grandis L.) DENGAN METODE ULTRASONIK (KAJIAN RASIO BAHAN : PELARUT DAN LAMA EKSTRAKSI) Januarti, Ika Buana; Santoso, Arifin; Razak, Akhdan Sultrawan
Media Farmasi Indonesia Vol. 12 No. 2 (2017): Media Farmasi Indonesia
Publisher : SEKOLAH TINGGI ILMU FARMASI YAYASAN PHARMASI SEMARANG

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (327.135 KB)

Abstract

ABSTRAKDaun jati selama ini banyak dimanfaatkan masyarakat sebagai obat tradisional dan pewarna alami karena mengandung senyawa flavonoid, alkaloid, tanin dan saponin. Ekstraksi modern dengan metode ultrasonik dapat menjadi pilihan untuk efisiensi dalam mengekstraksi senyawa di dalam daun jati karena pada metode konvensional membutuhkan waktu ekstraksi yang lama dan jumlah pelarut yang lebih banyak. Penelitian ini bertujuan untuk mengetahui pengaruh rasio bahan : pelarut serta lama ekstraksi terhadap kadar flavonoid menggunakan metode ultrasonik sehingga dihasilkan ekstrak daun jati terbaik. Metode penelitian ini adalah Rancangan Acak Kelompok (RAK) dengan 2 faktor yaitu rasio bahan : pelarut (1:5, 1:10, 1:15) dan lama ekstraksi 10, 20 dan 30 menit. Hasil terbaik dengan kadar flavonoid total paling tinggi adalah rasio bahan : pelarut 1 : 5 dan lama waktu ekstraksi 30 menit.
Edukasi dan Pengelolaan Gaya Hidup Penyakit Sindrom Metabolik Pada Lansia di Kecamatan Pedurungan, Semarang Januarti, Ika Buana; Maharyani, Airina; Anggraini, Monica Putri
Jurnal Pelayanan dan Pengabdian Masyarakat (Pamas) Vol 9, No 4 (2025): Jurnal Pelayanan dan Pengabdian Masyarakat (PAMAS)
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat (LPPM Universitas Respati Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52643/pamas.v9i4.5551

Abstract

Metabolic syndrome has an incidence rate of 25%. This disease has symptoms such as patients having an above-normal waist circumference ≥90 cm for males and ≥80 cm for females, hypertriglyceridemia, low HDL cholesterol levels, hypertension, and diabetes mellitus. Unhealthy lifestyle factors, such as a diet high in fat and sugar and a lack of physical activity, play an important role in the emergence of metabolic syndrome. This community service activity aims to increase public knowledge, especially among the elderly, about metabolic syndrome and healthy lifestyle management as a preventive measure. Education was conducted using lectures followed by interactive discussions. The effectiveness of the activity was measured by comparing pre-test and post-test results to assess participants' knowledge improvement. The activity was attended by 32 participants from RT 09, Pedurungan District, Semarang City. The evaluation results showed a 12% increase in knowledge afterthe education, with a good improvement category. Statistical analysis using the Paired Sample T-Test showed a significant difference between the pre-test and post-test scores with a significance value of 0.004 (p < 0.05). These findings indicate that the educational activity had a significant effect on increasing the community's knowledge about metabolic syndrome and the importance of adopting a healthy lifestyle.
Pengaruh Variasi Konsentrasi Pada Sediaan Krim Ekstrak Daun Kelor (Moringa oleifera L) Terhadap Uji Aktivitas Antibakteri Staphylococcus aureus Latifah, Fadzil; Januarti, Ika Buana; Amalina, Nur
Indonesian Journal of Medical and Pharmaceutical Science Vol. 1 No. 1 (2022)
Publisher : Sultan Agung Islamic University of Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/ijmps.v1i1.5

Abstract

Latar Belakang : Bakteri Staphylococcus aureus merupakan penyebab penyakit antara lain jerawat, bisul, impetigo,dan infeksi pada luka. Beberapa senyawa yang terkandung didalam daun kelor berperan sebagai antibakteri. Tujuan penelitian ini adalah untuk mengetahui konsentrasi 5%, 10%, 15% sediaan krim ekstrak etanolik daun kelor (Moringa Oleifera L.) yang dapat menghambat pertumbuhan bakteri Staphylococcus Aureus. Metode : Penilitian ini bersifat eksperimental dengan post test only control group design. Ekstraksi menggunakan metode maserasi pelarut etanol 96%. Penelitian ini menggunakan 5 kelompok yaitu kontrol positif (K+), kontrol negatif (K-), formula 5% (F1), formula 10% (F2) dan formula 15% (F3). Pengujian sifat fisik sediaan krim meliputi organoleptis, pH, daya sebar dan viskositas. Uji efektivitas antibakteri menggunakan metode difusi cakram. Hasil : Hasil uji sifat fisik menunjukkan bahwa pada pengujian pH didapatkan nilai rata-rata yaitu kelompok basis (6,98), kelompok F1 (6,98), kelompok F2 (6,98), kelompok F3 (6,98). Uji daya sebar didapatkan nilai rata-rata yaitu kelompok basis (6,5 cm), kelompok F1 (5,77 cm), kelompok F2 (6,6 cm), kelompok F3 (6,6). Uji viskositas didapatkan nilai rata-rata yaitu kelompok basis (304,56 cps), kelompok F1 (302,73 cps), kelompok F2 (311,06 cps), kelompok F3 (312,06 cps), hasil uji aktivitas antibakteri didapatkan rata-rata hasil yaitu kelompok kontrol negatif (0 cm), kelompok kontrol positif (18 cm), kelompok F1 (14,6 cm), kelompok F2 (20,63 cm), kelompok F3 (25,46 cm). Kesimpulan : Kesimpulan penelitian ini adalah sediaan krim ekstrak daun kelor 5% mempengaruhi aktivitas antibakteri secara lemah, 10% secara sedang, 15% secara kuat dan semua sediaan krim memenuhi persyaratan uji sifat fisik.
Pengaruh Konsentrasi PVA Terhadap Aktivitas Antioksidan Dan Sifat Fisik Masker Gel Peel Off Ekstrak Etanolik Daun Putri Malu (Mimosa pudica L) Krisya, Otta Ganes; Januarti, Ika Buana; Susmayanti, Windi
Indonesian Journal of Medical and Pharmaceutical Science Vol. 2 No. 1 (2023)
Publisher : Sultan Agung Islamic University of Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/ijmps.v2i1.91

Abstract

Background: The leaves of Putri malu (Mimosa pudica L.) contain flavonoid compounds which act as antioxidants to prevent and reduce the effects of free radicals on the skin. The potency of this ingredient is formulated into a peel-off mask with a PVA gel base because it can help penetrate the active substance into the skin by forming a strong and plastic film that provides good contact between the drug and the skin. The purpose of this study was to determine the effect of PVA concentration on the physical properties and antioxidant activity of the Mimosa Pudica L. ethanolic extract peel-off gel mask. Methods: The leaves of Putri malu were extracted by maceration using 70% ethanol and then peel-off mask preparations were made with PVA concentrations of 8%, 10% and 12%. The masks were tested for physical properties including organoleptic tests, pH strength tests, viscosity and dry time tests as well as antioxidant activity. The data obtained was then analyzed using One Way ANOVA and Kruskall Wallis. Results: EEDPM Peel-Off Mask formula 1 produced an IC50 of 5.505 μg/ml, formula 2 1.088 μg/ml and formula 3 0.606 μg/ml which means that the three formulas have strong antioxidant activity. Conclusion: The higher the concentration of PVA in the ekstrak etanolik daun putri malu (EEDPM) peel-off gel mask, the stronger the antioxidant activity.
Co-Authors Anggraini, Monica Putri Arifin Santoso Azizah, Na'ilatul Fadzil Latifah, Fadzil Fatmawati, Nur Fidia Krisya, Otta Ganes Maharyani, Airina Masithoh, Annisa Nisa, Anna Khoirun Nur Amalina Razak, Akhdan Sultrawan Susmayanti, Windi