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Pulmonary Resection in Complicated Primary Pediatric Pulmonary Tuberculosis: An Evidence-based Case Report Wibowo, Hendra; Wardoyo, Suprayitno; Shinta, Dhama
The New Ropanasuri Journal of Surgery
Publisher : UI Scholars Hub

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Abstract

Introduction. Paediatric pulmonary tuberculosis incidence was increasing, with many undetected cases. Antituberculosis regiments are known to be the treatment of choice for tuberculosis. Even though pulmonary resection for pulmonary tuberculosis has reduced in daily practice, it remains continues to play an important role in several advanced conditions and complications. Currently, there are no specific practical guidelines concerning surgical indications and approaches for pulmonary tuberculosis. We report a case with complicated primary paediatric pulmonary tuberculosis underwent resection and looking for the literature of the best evidence. Method. A case report completed with a discussion based on the best evidence. The database used for the literature search were Cochrane, Medline, ProQuest, and ScienceDirect. Keywords for the search were “primary pulmonary tuberculosis”, “surgery”, “Lung resection”, and “children”. Inclusion criteria were studies in English, children under 18 years old as the subject, and full-text articles available. The assessment carried out according to Oxford Centre for Evidence-Based Medicine 2011. Results. Six cohort studies were analyzed. Surgery indicated for patients with complicated TB that were unresponsive towards treatment. It should be noted that the experiments were done before the standard WHO antituberculosis therapy was applied. Thus, the result may be different from the current application. Conclusion. Currently, there was no guideline on pulmonary resection. However, surgery yielded better mortality and morbidity in children with complicated pulmonary tuberculosis.
Evaluation of myocardial injury from use of aortic cross-clamp and cardiopulmonary bypass duration in patients undergoing tetralogy of Fallot corrective surgery Wardoyo, Suprayitno; Djer, Mulyadi M.; Busro, Pribadi Wiranda
Paediatrica Indonesiana Vol. 65 No. 2 (2025): March 2025
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi65.2.2025.147-55

Abstract

Background Much remains unknown about the myocardial injury caused by aortic cross-clamp and cardiopulmonary bypass durations in children undergoing open-heart surgery, especially children with cyanotic congenital heart disease. To assess this injury, specific biomarkers can provide valuable insights. Troponin I (TnI) is known to be a specific marker of heart damage, while serum lactate serves as an indicator of tissue hypoperfusion and ischemic events. Additionally, malondialdehyde (MDA) is recognized as a marker of oxidative stress resulting from CPB machine usage. Objective To investigate the association of aortic cross clamp and CPB durations on myocardial injury and oxidative stress in children undergoing TOF corrective surgery. Methods We conducted this prospective study which included 29 patients diagnosed with TOF and who underwent corrective surgery. Troponin I and MDA levels were measured before surgery, 1 hour after surgery, and 8 hours after surgery. Lactate levels were measured in arterial blood specimens taken before surgery, as well as 1 hour, 6 hours, 12 hours, and 24 hours after surgery. Results Twenty-nine patients were included in this study and divided into groups based on aortic cross-clamp duration: shorter (<38 minutes) or longer (≥38 minutes), as well as based on CPB duration: shorter (<75 minutes) or longer (≥75 minutes), according to the median. Wilcoxon test indicated For the <38 min clamp duration group, there was only a significant increase in TnI at 1 hour compared to pre-op (P=0.048). However, there were no significant different in TnI, MDA, or lactate levels at any time point between the two CPB or cross-clamp groups.
A Fatal Case of Descending Necrotizing Mediastinitis as a Result of Treatment Delay in Odontogenic Infection: Various Bacterial Infections and Coexisting Lung Tuberculosis Husen, Theresia Feline; Sari, Grace Natalia; Gunawan, Putri Amadea; Vidya, Ananda Pipphali; Wardoyo, Suprayitno
Jurnal Respirasi Vol. 11 No. 2 (2025): May 2025
Publisher : Faculty of Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jr.v11-I.2.2025.153-158

Abstract

Introduction: Descending necrotizing mediastinitis (DNM) is a rare but life-threatening complication of oropharyngeal and odontogenic infections. This case report highlighted that DNM is very complex because it causes infection with various types of bacteria, and the presence of pulmonary tuberculosis (TB) in the patient. Case: A patient with untreated pulp gangrene for three months underwent drainage and tooth extraction surgery. Subsequently, the patient was diagnosed with DNM and underwent cervicotomy and sternotomy for debridement. Postoperative cultures revealed polymicrobial infections. Additionally, a follow-up chest X-ray confirmed active pulmonary TB. The simultaneous presence of multiple bacterial infections and TB necessitated aggressive treatment, including broad-spectrum antibiotics, anti-TB drugs per standard regimens, and close intensive care unit (ICU) monitoring. Over a month of ICU care, the patient’s vital signs and postoperative wounds improved. This case was classified as Endo-Hasegawa IIC DNM caused by odontogenic infection with pulp gangrene, progressing from the submandibular space to the mediastinum. The coexisting pulmonary TB further complicated management. Drainage via cervicotomy and sternotomy allowed for extensive mediastinal exploration. However, delayed diagnosis led to complications, including sepsis and altered consciousness due to uncontrolled bacterial spread. This underscores the importance of early diagnosis and intensive, multidisciplinary management to improve outcomes. Conclusion: Physicians need to be more aware of DNM as a potential complication of odontogenic infections and the possibility of a wide variety of bacterial and coexisting infections that may complicate treatment.
Morel-Lavallée Lesion with Chronic Osteomyelitis Mimicking Gynecomastia: Diagnostic Challenges in a Post-Trauma Case Tanujaya, Jason Clark Chen; Wardoyo, Suprayitno
Eduvest - Journal of Universal Studies Vol. 5 No. 7 (2025): Eduvest - Journal of Universal Studies
Publisher : Green Publisher Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59188/eduvest.v5i7.50844

Abstract

A Morel-Lavallée Lesion (MLL) is a soft tissue injury caused by the sudden detachment of the skin and subcutaneous tissue from the underlying fascia, resulting in a closed degloving injury. It is often complicated by chronic osteomyelitis, which can present diagnostic challenges. We report a case of a 36-year-old male patient who developed an MLL with chronic osteomyelitis, initially mimicking gynecomastia. The patient presented with a mass in the chest area months after trauma, and clinical examination was inconclusive, with a history of diabetes mellitus and the lesion's proximity to the breast tissue complicating the differential diagnosis and raising suspicion for gynecomastia. However, a CT scan of the thorax revealed a MLL with underlying bone involvement, indicating chronic osteomyelitis. This case highlights the diagnostic challenges when typical findings may be misleading, emphasizing the need for comprehensive imaging and clinical correlation for accurate diagnosis and appropriate management.
Successful prolonged intermittent renal replacement therapy in managing isolated coronary artery bypass graft surgery-associated acute kidney injury: A case report Huzaiby, Adam; Wardoyo, Suprayitno
Journal of Indonesia Vascular Access Vol. 4 No. 1 (2024): (Available online : June 2024)
Publisher : Indonesian Vascular Access Association (IVAA)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51559/jinava.v4i1.34

Abstract

Introduction: Unstable angina pectoris is one of the most underappreciated conditions by emergency department doctors. Unfortunately, the UAP is a type of heart attack that is usually caused by the deadliest type of CAD, namely the left main disease and three-vessel diseases. Both types are excellent candidates for operative revascularization with a satisfying result. Not infrequently, the acute renal complications after CABG surgery often become catastrophic. This study aims to evaluate our experiences in managing our patients with AKI following a conventional CABG surgery as a postoperative complication. Case description: A 69-year-old man was admitted to the ward to undergo a scheduled elective CABG surgery on the following day. The patient has a history of UAP, and a CAG study that was done three weeks earlier indicated that the culprit was a left main disease. The LIMA was anastomosed to the distal segment of the LAD, and one graft of GSV was anastomosed to the OM. Following the surgery, the patient experiences an unstable rapid response of AF and stage three AKI. Eventually, the patient must undergo two times of SLEDDs. After a second dialysis, the patient’s serum creatinine was lowered and the stage of the AKI was downgraded. After close monitoring for fifteen days, the patient’s serum creatinine gradually became normal. The dialysis access is removed, and the patient does not need a subsequent routine dialysis following discharge from our hospital. Conclusion: The incidence of AKI following CABG surgery can be multifactorial. An alternative technique instead of using a CPB machine, judicious use of blood products, and prevention and treatments of a POAF should be considered. The PIRRT can be chosen as an alternative modality to CRRT with the same outcome quality for managing stage three AKI following CABG surgery.
Bidirectional Cavopulmonary Shunt Surgery of Tetralogy of Fallotwith Situs Inversus and Levocardia in 20-Month-Old Boy : A Rare Case Report Wardoyo, Suprayitno; Susanti, Dhama Shinta; Makdinata, William; Jeo, Albert
Jurnal Health Sains Vol. 4 No. 10 (2023): Journal Health Sains
Publisher : Syntax Corporation Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46799/jhs.v4i10.1099

Abstract

Tetralogy of Fallot (TOF) is a relatively common cyanotic congenital heart disease, characterized by four distinct defects. Although TOF is a common condition, its association with situs inversus and levocardia is rare, presenting diagnostic and treatment challenges. This case report discusses a 20-month-old boy with TOF, situs inversus, and levocardia. Initially planned for total surgical correction, intraoperative anatomical complexities led to the decision to perform a bidirectional cavopulmonary shunt surgery. This procedure aimed to enhance oxygen saturation and reduce the volume load on the right ventricle, due to severe pulmonary stenosis and perimembranous ventricular septal defect. The bidirectional cavopulmonary shunt serves to improve systemic arterial oxygen without increasing ventricular work or pulmonary vascular resistance. This case highlights the significance of individualized treatment approaches when TOF is associated with complex anatomical variations