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THE EFFECT OF COGON GRASS ROOT ETHANOL EXTRACT ON REPRODUCTIVE ORGAN AND EPIDIDYMAL SPERM QUALITY OF MOUSE WITH DIFFERENT AGES Sudiman, Jaqueline; Widyastuti, Rini; Lubis, Alkaustariyah; Hartady, Tyagita; Syamsunarno, Mas Rizky Anggun Adipurna; Sumarsono, Sony Heru
Jurnal Kedokteran Hewan Vol 14, No 1 (2020): March
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.ked.hewan.v14i1.14969

Abstract

This study aims to determine changes related to epididymal sperm parameters in mice given cogon grass root ethanol extract (CGREE). The experiment was carried out by dividing three groups of mice aged 4-week old (early pubertal), 8-week old (adult), and 24-week old (old) as control and treatment groups. The treatment groups were given 115 mg/kg body weight of CGREE for 14 days. The mice were sacrificed on day 15 to asses reproductive organ indexes and quality of the epididymal sperm. Index of epididymis and ductus deferens indices significantly reduced in the 4-week old treatment group compared to control (0.23 vs 0.33; 0.08 vs 0.16, respectively), and vesical seminal significantly reduced in 8- week old treatment group compared to control (0.76 vs 0.68). The epididymal sperm quality significantly decreased in all treatment groups, but the sperm concentration in early pubertal group showed an increase. These results indicate that CGREE can enhance several semen parameters in prepubertal and adult mice but this effect is not apparent in old mice.
Gait Parameters and Fall Risk Among Older Adults in Tabanan Regency Dewi, Ni Putu Indira Prana; Wirata, Gede; Sudiman, Jaqueline; Muliani
Babali Nursing Research Vol. 7 No. 1 (2026): January
Publisher : Babali Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37363/bnr.2026.71547

Abstract

Introduction: Fall risk is a major geriatric concern linked to age-related gait instability. Changes in gait parameters, such as step length, step width, and walking speed, reflect neuromuscular decline and increase instability. While international evidence supports this association, local data among community-dwelling older adults in Tabanan Regency, Bali, remain limited. This study aimed to examine the association between gait parameters and fall risk.Methods: This cross-sectional observational study included 119 community-dwelling adults aged 60–79 years. Gait parameters, including step length, step width, and walking speed, were assessed using the 10-meter walk test, and fall risk was measured using the Timed Up and Go (TUG) test. Chi-square tests were used for bivariate analysis, and binary logistic regression was used to identify independent predictors.Results: A total of 36.1% of participants were classified as at risk of falling. Bivariate analysis showed significant associations between fall risk and step length (p = 0.050), step width (p = 0.006), walking speed (p < 0.001), and age (p < 0.001). Multivariate analysis identified walking speed (AOR = 0.150; p = 0.005), leg-length symmetry (AOR = 0.292; p = 0.026), and step width (AOR = 0.345; p = 0.038) as independent predictors. Step length was excluded from the multivariate analysis due to complete separation in the data.Conclusion: Walking speed, step width, and leg-length symmetry were independent predictors of fall risk. These findings support the use of simple gait assessments for early fall risk screening in community and primary care settings.