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All Journal Jurnal Al-Ijtimaiyyah Jurnal Penelitian Pendidikan IPA (JPPIPA) EJI (English Journal of Indragiri) : Studies in Education, Literature, and Linguistics Asatiza: Jurnal Pendidikan
Ridhwan, M.
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Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Education Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Physics Social Sciences

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Journal : Jurnal Penelitian Pendidikan IPA (JPPIPA)

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Protective Potential of Kersen Leaf Ethanol Extract (Muntingia calabura L.) Against Hepatic Histopathology in Diabetes Mellitus Model Rats Andalia, Nurlena; Ridhwan, M.; Elvitriana; Armi; Jailani
Jurnal Penelitian Pendidikan IPA Vol 11 No 5 (2025): May
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v11i5.10862

Abstract

Kersen leaves (Muntingia calabura L.) are known as herbal plants used to lower blood glucose levels. This study evaluated the protective effect of ethanol extract of kersen leaves on the histopathology of the liver of white rats (Rattus norvegicus) model of diabetes mellitus. The experimental study with a Complete Randomized Design (RAL) involved five treatment groups and three replicates, using 55 streptozotocin (STZ)-induced mice. The results showed that the administration of 15% (K5) of kersen leaf ethanol extract improved the structure of hepatocytes, resembling normal tissue, compared to the positive control group (K2) who experienced severe necrosis and degeneration. In conclusion, 15% kersen leaf ethanol extract is effective in improving liver damage due to diabetes and potentially lowering blood glucose levels.
Co-Authors Andalia, Nurlena Armi Armi, Armi Elvitriana Furqan Furqan, Furqan Husna, Ana Imroatul Ihsan, Muhammad Taufik Jailani Kasful Anwar Us, Kasful Anwar Khairani, Yuli Lias Hasibuan Lukmanul Hakim Melda Yeni Muchsin Muchsin Muchsin Muchsin Naskah, Naskah Noviyanti, Anita siswanto, iwan Surya, Erdi Yudhyarta, Deddy Yusuf Yurisa, Anggi