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Advancements in NMR and IR Spectroscopy: Enhancing Metabolomics and Disease Diagnostics in the Health Sector: A Comprehensive Review Saputra, Rizki Rachmad; Ariefin, Mokhamat; Kumalasari, Meiyanti Ratna; Dongoran, Junita; Tampubolon, Mulani Jeni Lestari; Sulistiawati, Putri; Simangunsong, Sri Yulandari; Ariska, Risya; Paksi, Pandu Gizta Rapi; Siska, Amelia; Yanti, Jeddah; Maknun, Luluil
Indonesian Journal of Chemical Analysis (IJCA) Vol. 7 No. 2 (2024): Indonesian Journal of Chemical Analysis
Publisher : Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/ijca.vol7.iss2.art6

Abstract

Metabolomics has emerged as a critical field in understanding biological processes and disease mechanisms, necessitating advancements in analytical techniques to handle complex biological samples. This review explores the global landscape of metabolomics, with a focus on the use of spectroscopy and spectrometry. Techniques such as UV-Vis and Fourier Transform InfraRed (FTIR) spectroscopy offer fast and cost-effective metabolite tracing but are limited by their sensitivity, particularly for low-abundance metabolites. Nuclear Magnetic Resonance (NMR) spectroscopy, despite being less sensitive than mass spectrometry (MS), provides unparalleled structural information, distinguishing metabolites with similar mass-to-charge ratios. NMR's capability to detect metabolites in the 1-10 µM range highlights its effectiveness in metabolomics. This review categorizes advancements in these techniques, starting with global contributions to spectroscopy, followed by detailed discussions on FTIR strategies for metabolite tracing, and concluding with NMR's qualitative and quantitative applications in metabolomics and disease diagnostics. The review underscores the continuous development in sample preparation and data integration, enhancing the accuracy and applicability of these techniques, positioning NMR and FTIR as essential tools in modern metabolomic research.
Reinterpretation of Gender Values in Islam: A Critical Study from a Contemporary Feminist Perspective Maknun, Luluil; Zakaria, Muhammad Fadhlurrahman
Jurnal Kajian Gender dan Anak Vol 9, No 1 (2025)
Publisher : Universitas Islam Negeri Syekh Ali Hasan Ahmad Addary Padangsidimpuan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24952/jkga.v9i1.15758

Abstract

Reinterpretation of gender values in Islam has the potential to continue to shine and develop more widely to uphold gender equality despite the many challenges that must be faced. The purpose of this study is to find out in detail about the reinterpretation and interpretation of gender values in Islam based on religious texts such as the Qur'an and Hadith, to find out how the relationship between gender values from the perspective of Islamic feminism and the perspective of contemporary feminism, and to find out the challenges and solutions that Islamic feminism must do in fighting for Islamic gender values so that they continue to shine on the world stage. The method used in this article is descriptive-analytical using a comparative theory between Islamic feminist theory and contemporary feminism. And in this article the researcher reveals several findings including: Muslim feminists argue that many traditional interpretations do not fully reflect the original message of the Qur'an, especially regarding gender equality issues. Therefore, a deeper interpretation of religious texts that discuss these issues must be carried out. However, a significant challenge comes from conservative resistance in the Muslim community, who consider this approach a threat to Islamic teachings and culture. This research is very important to be reviewed in depth because the urgency of this research must be disseminated so that many people know the struggle of Islamic feminism to raise Islamic gender values in the modern era.
Penerapan Model Pembelajaran Flipped Classroom Berbantuan Lumi Education Terhadap Kemampuan Pemecahan Masalah Matematis dan Kemandirian Belajar Siswa Maknun, Luluil; Azizah, Dewi
Imajiner: Jurnal Matematika dan Pendidikan Matematika Vol 8, No 4 (2026): Imajiner: Jurnal Matematika dan Pendidikan Matematika
Publisher : Universitas PGRI Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26877/imajiner.v8i4.27953

Abstract

This study aims to analyze the differences in students’ mathematical problem-solving abilities and learning independence between students taught using the Lumi Education-assisted flipped classroom model and students taught using the expository model on the topic of sequence and series applications. This research employed a quasi-experimental design with a quantitative approach, using a non-equivalent posttest-only control group design. The research sample was selected using cluster random sampling technique, with class XI Hosfour 1 as the experimental group and class XI Hosfour 2 as the control group. Data analysis was conducted using the R program, employing Hotelling's T² test for multivariate analysis, and Mann-Whitney and Independent T-test for univariate analysis. The results showed that: 1) there was a significant simultaneous difference between the two groups, with a p-value = 1.028×10⁻⁵ 0.05, 2) there was a significant difference in mathematical problem-solving ability, with a p-value = 2.348×10⁻⁵ 0.05, and 3) there was no significant difference in learning independence, with a p-value = 0.684 0.05. This study concludes that the Lumi Education-assisted flipped classroom model has a significant effect on mathematical problem-solving ability, while it has no significant effect on learning independence.