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The Use of Natural Phenomenon in Obtaining Pregnant Rats and Mice as Experimental Animals with The Same Gestational Ages Sardjono, Teguh Wahju; Gondo, Harry Kurniawan; Nugraha, Rivo Yudhinata Brian; Putri, Anisa Tiara; Effendy, Meyland Citra Oktri Sienty
Journal of Tropical Life Science Vol 9, No 3 (2019)
Publisher : Journal of Tropical Life Science

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Abstract

Hormonal oestrus synchronization is often used to obtain the same gestational ages animal models, but it may not physiologic nor practical. This research was conducted to find out a simple method in obtaining physiologic pregnant experimental animals. We used 120 female rats and mice each, divided into 16 groups with 15 members each. They were classified according to the state of parities, pair or group mating, and synchronization of oestrous. The estrous synchronization is done by utilizing the natural phenomenon (Lee-Boot, Pheromone, and Whitten effect). All nulliparous and multiparous models then were simultaneously mated for one night in pairs (1:1) or in groups (1:5) subsequently. Pregnancy rates were noted based on the number of models delivering pups on day 19-23 post-mating. The highest pregnancy rate was noted in group of multiparous, synchronized and monogamous rats (86.7%), followed by nulliparous, synchronized and monogamous rats (73.3%) and multiparous, synchronized and monogamous mice (60%) (p<0.05). Synchronization of the estrous and monogamous mating of rats or mice had significant roles in pregnancy rates (p<0.05). To get a high number of pregnant rats or mice models, we suggest to use the multiparous, estrous synchronized and monogamous simultaneous mating within one night.
Reformulation of Regulatory Protection for Resident Doctors Against Bullying in Specialist Medical Education Effendy, Meyland Citra Oktri Sienty; Anwar; Fikri, Ahmad Ma’mun
Research Horizon Vol. 5 No. 4 (2025): Research Horizon - August 2025
Publisher : LifeSciFi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54518/rh.5.4.2025.746

Abstract

The phenomenon of bullying against participants in the Medical Specialist Education Program within teaching hospital environments highlights structural inequalities and legal gaps in Indonesia’s advanced medical education system. This study aims to analyze legal issues concerning the protection of professional education for specialist Doctor participants from psychological violence and bullying, while proposing an ideal regulatory reformulation to safeguard their rights. Employing normative legal research methods with legislative, doctrinal, and responsive legal theory approaches, the study reveals that existing regulations such as Law Number. 20 of 2013 on Medical Education fail to provide explicit protections for professional education for specialist Doctor participants. Meanwhile, the Minister of Health’s Instructions remain merely administrative and lack legally binding force. Regulatory reform should clearly define professional education for specialist Doctor participants’ status within the national education system, specify the rights and obligations of program organizers and participants, establish an independent anti-bullying task force, and implement monitoring mechanisms and administrative sanctions. A victim-oriented, responsive regulatory framework would not only protect trainees’ rights but also enhance the quality of medical education and national healthcare services. The state must act promptly through progressive legislation to eradicate bullying practices and ensure a fair, humane educational environment for professional education for specialist Doctor participants.