Article Per Year (5 Year)
p-Index From 2021 - 2026
0.23
P-Index
This Author published in this journals
All Journal Jurnal Biologi Tropis Dynamic Management Journal
Nursiah, Siti
Unknown Affiliation
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Immunology & microbiology Other

Published : 2 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search

 1 
PENGARUH BEBAN KERJA DAN KOMUNIKASI TERHADAP PRODUKTIVITAS KERJA KARYAWAN PADA PT WONEEL MIDAS LEATHERS DI TANGERANG Nursiah, Siti
Dynamic Management Journal Vol 3, No 1 (2019): January
Publisher : Universitas Muhammadiyah Tangerang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31000/dmj.v3i1.1708

Abstract

Penelitian ini bertujuan untuk mengetahui Pengaruh beban kerja dan komunikasi terhadap produktivitas kerja karyawan pada PT. Woneel Midas Leathers di Tangerang. Metode penelitian ini menggunakan penelitian kuantitatif. Jumlah populasi yang penelitian ini sebanyak 200 dengan jumlah sampel sebanyak 67 orang dengan taraf kesalahan 10%. Data yang dikumpulkan menggunakan metode angket dengan skala Likert dan wawancara. Metode analisis penelitian ini menggunakan (1) Uji Validitas, (2) Uji reabilitas, (3) Analisis regresi sederhana, (4) Analisis regresi berganda, (5) Analisis korelasi sederhana, (6) Analisisis korelasi berganda, (7) Analisisi koefisien determinasi, (8) Uji t, (9) Uji f.Hasil penelitian ini menunjukkan bahwa: (1) Beban Kerja berpengaruh terhadap Produktivitas kerja karyawan dapat dilihat dari hasil perhitungan analisis regresi sederhana yaitu Y = 22,550 + 0,441X1. (2) Komunikassi berpengaruh terhadap Produktivitas Kerja Karyawan dari hasil perhitungan analisis regresi sederhana yaitu Y = 22,240 + 0,439X2. (3) beban kerja dan komunikasi berpengaruh terhadap produktivitas kerja dapat dilihat dari hasil perhitungan analisis regresi ganda yaitu Y = 16,739 + 0.268X1 + 0.324X2. (4) R Square Beban Kerja dan Komuikasi dengan Produktivitas Kerja adalah sebesar 0.503.Kata Kunci: Beban Kerja, Komunikasi, Produktivitas Kerja Karyawan
Relationship between TIM-3 Immune Response Expression and Nasopharyngeal Carcinoma Histopathology Harahap, Vina Andita; Farhat, Farhat; Nursiah, Siti; Yudhistira, Ashri; Sitompul, Ramlan; Harahap, Juliandi
Jurnal Biologi Tropis Vol. 25 No. 4a (2025): Special Issue
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v26i1.11659

Abstract

Nasopharyngeal carcinoma is a malignancy of the nasopharyngeal epithelium that is often diagnosed at an advanced stage and is associated with impaired immune regulation in the tumor microenvironment. T-cell immunoglobulin and mucin domain-3 (TIM-3) is an immune checkpoint molecule that plays a role in suppressing the antitumor immune response. This study aims to analyze the relationship between TIM-3 immune response expression and the histopathological type of nasopharyngeal carcinoma. An analytical study with a cross-sectional design was conducted on 40 paraffin blocks of nasopharyngeal carcinoma patients at H. Adam Malik General Hospital, Medan, selected by consecutive sampling. TIM-3 expression was analyzed using real-time polymerase chain reaction (RT-PCR) with the calculation of ΔCT values against the control gene β-actin. Univariate analysis was used to describe the characteristics of the subjects, while bivariate analysis used the Kruskal–Wallis test to assess the relationship between TIM-3 expression and histopathological type. The majority of subjects were male (65%) with a mean age of 48.2 ± 11.1 years. The most common histopathological type was non-keratinizing squamous cell carcinoma (90%). The mean TIM-3 expression was 4.3 ± 1.6 with a median of 4.8 (−0.1–6.7), and 97.5% of samples showed increased expression. The Kruskal–Wallis test showed no significant correlation between TIM-3 expression and histopathological type (p = 0.452). It was concluded that TIM-3 expression is generally increased in nasopharyngeal carcinoma, but is not significantly associated with histopathological type. Further research is needed to evaluate the biological role and therapeutic potential of TIM-3 in this disease.
Co-Authors Farhat, Farhat Harahap, Juliandi Harahap, Vina Andita Sitompul, Ramlan Yudhistira, Ashri