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Kahar, Fitriani
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Gambaran Kepositifan Basil Tahan Asam Pasien Diagnosis Klinis Tuberculosis Paru di Balai Kesehatan Masyarakat Semarang Kahar, Fitriani; Novitasari, Putri Anggraeni; Irnawati, Irnawati
Jaringan Laboratorium Medis Vol. 4 No. 2 (2022): November 2022
Publisher : Poltekkes Kemenkes Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jlm.v4i2.8552

Abstract

Tuberculosis is an infectious disease caused by Mycobacterium tuberculosis. Until now, tuberculosis is still a public health problem in the world. Tuberculosis is a dangerous infectious disease, the healing process also takes a long time. Acid-fast bacilli examination is an examination to determine the presence or absence of Mycobacterium tuberculosis bacteria. The factors that influence Tuberculosis patients are age, gender, education and occupation. The purpose is to knowing the description of AFB positivity in patients with clinical diagnosis of pulmonary tuberculosis at Balkesmas Semarang in 2020. This research was an observational study with descriptive research criteria through a retrospective approach. Results from 656 patients with clinical diagnosis of tuberculosis who underwent acid-fast bacilli examination, 220 patients (33.5%) were found positive and acid-fast bacilli were negative (64.5%). The results of the examination of acid-fast bacilli were positive with a scanty positivity degree of 3 patients (1.4%), acid-fast bacilli (+1) were 71 patients (32.3%), (+2) were 83 patients (37.7%), (+3) as many as 63 patients (28.6%). Based on the category of age 0-14 years as many as 1 patient (0.5%), 15-34 years as many as 78 patients (35.5%), 35-54 years as many as 96 patients (43.6%), 55-74 years as many as 44 patients (20%), >75 years as many as 1 patient (0.5%). Based on gender, there were 123 patients (56%) male and 97 female patients (44%). Conclusion the results of the examination of acid-fast bacilli were positive with a scanty positivity rate of 3 patients (1.4%), acid-fast bacilli (+1) 71 patients (32.3%), (+2) 83 patients (37.7%), (+3) 63 patients (28.5%). Based on gender with positive acid-fast bacilli, there were 123 male patients (56%) while female 97 patients (44%). Age with the most positive acid-fast bacilli results in the range 0–14 years 1 patient (0.5%), 15–34 years 78 patients (35.5%), 35-54 years 96 patients (43.6%), 55 –74 years.
Perbandingan Hasil Pemeriksaan Protein Urine Metode Carik Celup, Asam Asetat 6%, dan Asam Sulfosalisilat 20% Menggunakan Aturan Westgard Permata Sari, Cecilia Febiyono; Kahar, Fitriani; Irnawati, Irnawati; Yusuf, Muhammad; Salam, Abdul; Wadood, Abdul
Jaringan Laboratorium Medis Vol. 5 No. 2 (2023): November 2023
Publisher : Poltekkes Kemenkes Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jlm.v5i2.9784

Abstract

Proteinuria is caused by kidney damage. Qualitative examination of urine protein can be carried out using the dip strip method, 6% acetic acid and 20% sulfosalicylic acid. The aim of this research is to determine the accuracy and precision of urine protein examination using the dip strip method, 6% acetic acid and 20% sulfosalicylic acid. The research was experimental with repeated measurements of levels carried out visually and gave positive results of 1, 2, 3 and 4. The research was carried out in January 2022 using a research sample of 20 proteinuria positive patients at RSJD Dr. Amino Gondohutomo. The results of this research are that all methods meet the 12S rules where there is 1 control that is more than ± 2SD (still in the ± 3SD area), categorized as a warning/warning of method malfunction (needs more careful analysis). The best method is dip strip because it has the lowest Coefficient of Variation (KV) value, namely 0.497%. The method can still be used for patient care. The coefficient of variation obtained was dye liquid 0.497%, 6% acetic acid 0.654%, and 20% sulfosalicylic acid 0.630%. The smaller the KV value (%) the more thorough the system/method. The conclusion that can be drawn from this research is that the dip strip is a method that has the best accuracy and precision compared to the 6% acetic acid and 20% sulfosalicylic acid methods because it has the smallest coefficient of variation (KV%) value, namely 0.497% and meets the 12S rules. Researchers recommend always ensuring that the research location has the required samples with adequate volume, urine protein examination can be carried out using the dip strip method, researchers can then carry out urine protein examination regarding the sensitivity and specificity of the three qualitative methods
Hubungan Kadar Kalium dan Kadar Ureum Terhadap Jenis Obat Baru pada Pasien Tuberkulosis Resistan Obat (TB RO) Anggita, Sasha Marwah; Qomariyah, Nurul; Kahar, Fitriani
Jaringan Laboratorium Medis Vol. 6 No. 1 (2024): May 2024
Publisher : Poltekkes Kemenkes Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jlm.v6i1.11388

Abstract

The use of new types of drugs in RO TB patients will cause disturbances in the body's electrolytes, especially potassium levels, as well as disturbances in urea levels caused by the excretion of urea that is retained in the body. Continuous increases in urea in the body result in the kidneys not being able to work optimally. The aim of this study was to determine the relationship between potassium levels and urea levels on new types of drugs in RO TB patients. The research method used is analytical observational with a cross sectional approach. This research was conducted on 16 February – 16 March 2023 with research subjects being RO TB patients who received treatment with a new type of drug at the Lung Hospital dr. Ario Wirawan Salatiga as many as 21 respondents using a sampling technique that is the total population. Potassium levels were measured using the ISE (Ion Selective Electrode) method and urea levels used the enzymatic UV test method. The data was then processed using the Shapiro-Wilk normality test, then continued with prerequisite tests (crosstab test and homogeneity test) then continued with hypothesis testing, because my data scale was ratio and nominal, the alternative test used was the Chi-Square Test. The equipment test results obtained a homogeneity test with a P value of 0.698 and 0.610 (>0.05), meaning the data was homogeneous. The test results for the relationship between potassium and urea levels on new types of drugs for RO TB patients were Chi-Square hypothesis test results with a P value of 0.152 and 0.384 (> 0.05) means there is no relationship between potassium levels and urea levels on new types of drugs in RO TB patients. The results show that the TB drugs bedaquiline and delamanid do not cause kidney function disorders so that RO TB patients can consume these TB drugs regularly.
Identifikasi Glukosa Urin dan Keton Urin pada Pasien Tuberkulosis Paru yang Mendapat Terapi Obat Anti Tuberkulosis (OAT) Di Puskesmas Tlogosari Wetan Hafidsya, Pradiana Syahwa; Kahar, Fitriani
Jaringan Laboratorium Medis Vol. 6 No. 2 (2024): November 2024
Publisher : Poltekkes Kemenkes Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jlm.v6i2.12199

Abstract

Tuberculosis is a contagious infection caused by Mycobacterium tuberculosis. Anti-Tuberculosis Drug Therapy (OAT) given also has side effects, one of which is nephrotoxic. Laboratory examination of urine glucose identification can indicate if there is damage to the kidney glomerulus in the filtration process. The purpose of this study was to identify urine glucose and urine ketones in non-DM pulmonary TB patients with OAT treatment at the Tlogosari Wetan Health Center. This type of research is descriptive observational with a cross-sectional approach. The population was all TB patients who underwent examination at the Tlogosari Wetan Health Center. The research sample was a random urine sample from non-DM pulmonary TB patients. The examination method used was a dipstick using a reagent strip test. The results showed that out of a total of 30 non-DM pulmonary TB patients with OAT therapy (100%). A total of 6 (20%) patients were identified with urine glucose, with details of  intensive phase treatment 2 (7%) patients with trace urine glucose (±), while in the continuation phase 2 (7%) patients were identified with trace urine glucose (±) and 2 (7%) patients with low urine glucose (+1). The majority of positive urine glucose results were experienced by males with an elderly age range (46-65 years) of 4 patients (14%). The results of urine ketone identification showed that 2 (6.6%) patients were identified with urine ketones, namely trace (±) in intensive phase treatment, while 15 patients in the continuation phase had all negative urine ketones. The majority of positive urine ketone results were experienced by males with an adult age range (26-45 years) of 2 patients (14%). The conclusion of 30 non-DM pulmonary TB patients with OAT therapy who met the inclusion criteria, there were 6 (20%) patients identified with urine glucose and 2 (6.6%) patients identified with urine ketones. The impact of this study is expected for non-DM pulmonary TB patients to take OAT and have regular medical check-up.
Hubungan Pengetahuan dengan Perilaku Ibu Hamil Usia Reproduksi Sehat dengan Pemeriksaan Triple Elliminatiom Skrining (HIV, Sifilis, dan Hepatitis B) Kahar, Fitriani
Jaringan Laboratorium Medis Vol. 7 No. 2 (2025): November 2025
Publisher : Poltekkes Kemenkes Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jlm.v7i2.12971

Abstract

Pregnant women are one of the populations at risk of contracting Sexually Transmitted Infections (STIs) such as HIV, Syphilis, and Hepatitis B. The prevalence of HIV/AIDS transmission from mother to child is 20-50% where 5-10% occurs during pregnancy. Syphilis transmission is 69-80% and Hepatitis B transmission is more than 90% with the potential for transmission during pregnancy and childbirth being very high. Based on the Regulation of the Minister of Health of the Republic of Indonesia, regulation No. 52 of 2017 concerning the Elimination Program for Transmission of Human Immunodeficiency Virus, Syphilis, and Hepatitis B from Mother to Child or often called "Triple Elimination" aims to stop transmission from mother to child with laboratory examinations on pregnant women at least once during pregnancy. The purpose of this study was to determine the relationship between knowledge and behavior of healthy reproductive age pregnant women in the first trimester at the Lebdosari Health Center. In general, this research method is qualitative with an analytical observational approach and cross-sectional design, namely researchers come and analyze the problem directly. Data collection is carried out at once within a certain time. The population is pregnant women in the first trimester at the Lebdosari Health Center, with a sample size of 49 people selected based on the Purposive Sampling technique. Data analysis was carried out descriptively and then continued with a bivariate test with the Kendal Tau test because the data was not normally distributed. The results of the study showed that the results of the bivariate test with the Kendal Tau test showed that there was no relationship between knowledge and behavior because the significance value p = 0.888> 0.05 with a positive correlation coefficient value (0.19) which means that there is a positive relationship between knowledge and behavior even though the relationship is weak because the value is less than 1, so that if knowledge increases, behavior will be better. It is recommended that pregnant women are advised to always maintain personal hygiene and implement a clean and healthy lifestyle to prevent infectious diseases.
Papaya Juice Treatment Increases Body Weight and Decreases Urea Levels in Lead acetate-exposed Wistar Rats Purlinda, Devi Etivia; Putri, Nanik Aryani; Widodo, Widodo; Kahar, Fitriani
JURNAL INFO KESEHATAN Vol 22 No 1 (2024): JURNAL INFO KESEHATAN
Publisher : Research and Community Service Unit, Poltekkes Kemenkes Kupang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31965/infokes.Vol22.Iss1.1148

Abstract

Lead (Pb) exposure poses significant health risks due to its non-degradable nature and profound toxicity, causes oxidative stress and organ damage, particularly targeting the kidneys. Urea nitrogen levels rise as a result of decreased renal filtration rate and urea excretion. This study investigates the potential of papaya juice, rich in flavonoids, vitamins C, E, and beta-carotene, as a protective agent against Pb-induced nephrotoxicity. A Completely Randomized Design experiment was conducted, involving six treatment groups of Wistar rats. Papaya juice was administered at doses of 3.6, 7.2, and 14.4 g/200g body weight (BW) to Groups P1, P2, and P3, respectively, prior to exposure to 50 mg/kg BW of lead acetate. Group PC received vitamin E (400 IU/kg BW) and lead acetate, while Group NC was exposed to lead acetate alone. Group NT served as the control. Following a 28-day treatment period, the P3 group exhibited the most significant improvements, with a notable increase in body weight (22.50 grams) and a substantial decrease in urea nitrogen levels (18.24 mg/dl). These findings underscore the efficacy of papaya juice treatment in mitigating Pb-induced nephrotoxicity, suggesting a potential therapeutic regimen for alleviating lead toxicity in exposed populations. Eventually, the optimal dosing for papaya juice treatment, either at 14.4 g per 200 g body weight for rats or consumption of one medium-sized papaya for humans, yields compelling benefits. This regimen demonstrates significant efficacy in increasing body weight and lowering serum urea levels in rats subjected to Pb acetate exposure.
BLOOD STORAGE ANALYSIS OF HEMOGLOBIN ERYTHROCYTE AND PLATELET LEVELS IN WHOLE BLOOD COMPONENTS 0 DAYS 7 DAYS UP TO 15 DAYS AND 30 DAYS AT THE INDONESIAN RED CROSS (PMI) BLOOD DONATION UNIT (UUD) SEMARANG REGENCY Riadi, Ahmad Riadi; Kahar, Fitriani; widodo, Widodo; Aprianti, Dina; Margi Rahayu, Umi
Journal of Applied Health Management and Technology Vol. 5 No. 4 (2023): October 2023
Publisher : Postgraduate Program , Poltekkes Kemenkes Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jahmt.v5i4.10626

Abstract

During the storage process, blood will experience changes in blood components such as hemoglobin levels. The longer blood is stored, the more red blood cells will be destroyed because blood that is stored for too long will experience a shift in the oxygen dissociation curve to the left. The aim of this study was to determine the effect of blood storage on the levels of platelets, erythrocytes and hemoglobin in the whole blood component of blood for 0 days, 7 days, 15 days and 30 days at the blood donor unit (UUD) of the Indonesian Red Cross (PMI) Semarang Regency. The type of research used is descriptive research, where this research aims to describe or provide an overview of the effect of storing blood in whole blood components on changes in platelet, erythrocyte and hemoglobin levels in PMI Semarang Regency. The population and research samples are donors in PMI Semarang Regency. Data analysis: Data processing is carried out by: Editing, namely selecting and correcting hemoglobin level data collected from the measurement results during each experiment. Tabulating is the presentation of research data in the form of tables of Hemoglobin reading results or descriptive or analytical analysis results. Processing is the activity of processing data so that it can be analyzed by entering data on hemoglobin levels. Cleaning or data checking is checking the hemoglobin level data that has been entered again to see if there are errors or not
Co-Authors Andi Patombongi Anggita, Sasha Marwah Aprianti, Dina Cakra Cakra Devi Etivia Purlinda Djoko Priyatno Efendi, Quirinus Hadipranoto, Ichsan Hafidsya, Pradiana Syahwa Irnawati Irnawati Muhammad Nur Muhammad Yusuf Novitasari, Putri Anggraeni Nurul Qomariyah Permata Sari, Cecilia Febiyono Purlinda, Devi Etivia Putri, Nanik Aryani Putri, Rianita Rachmad Bayu Kuncara Rahayu, Umi Margi Rahman, Baharuddin Riadi, Ahmad Riadi Rondonuwu, Ferawati Samsuddin Samsuddin Triyono, Damas Wadood, Abdul Widodo Widodo