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All Journal Biosel: Biologi Science and Education
Syafitri, Ulfah Eka
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Education Energy Environmental Science

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Journal : Biosel: Biologi Science and Education

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Analisis Fitokimia terhadap Senyawa Aktif dalam Daun Carica Papaya sebagai Dasar Formulasi Kapsul Kurniadi, Helman; Syafitri, Ulfah Eka; Alfiana, Dessinta; Framisa, Mentari; Hairani; Heldiana, Fitria
Biosel Biology Science and Education Vol. 14 No. 1 (2025): BIOSEL (Biology Science and Education: Jurnal Penelitian Science dan Pendidika
Publisher : INSTITUT AGAMA ISLAM NEGERI AMBON

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33477/bs.v14i1.9101

Abstract

Papaya leaves (Carica papaya L.) are rich in secondary metabolites with pharmacological potential as antioxidants, anti-inflammatories, and antimicrobials. This study aimed to identify bioactive compounds in papaya leaves, develop simplicia and extracts as a basis for capsule formulation, and evaluate the characteristics and stability of the resulting capsules. The methods used included simplicia preparation, extraction using maceration with 70% ethanol, phytochemical analysis using specific reagent tests, and capsule formulation with appropriate excipients. The results showed that papaya leaf simplicia had a moisture content of ≤ 5%, extraction yielded a rendement of 9.6%, and active compounds such as alkaloids, flavonoids, and polyphenols were detected. Capsule formulations containing papaya leaf extract showed good characteristics, with a dissolution time reaching 80% within 30 minutes, and good stability during storage. Papaya leaf extract can be developed as a stable, effective, and pharmaceutically standardized herbal phytopharmaceutical capsule preparation to support natural medicine. Keywords: C. papaya, Secondary Metabolites, Maceration, Herbal Capsule, Phytochemistry
Co-Authors Alfiana, Dessinta Framisa, Mentari Hairani Heldiana, Fitria Kurniadi, Helman