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Herikurniawan, Herikurniawan
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Medicine & Pharmacology

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Coronavirus Disease 2019: Review of Current Literatures Susilo, Adityo; Rumende, C. Martin; Pitoyo, Ceva W; Santoso, Widayat Djoko; Yulianti, Mira; Herikurniawan, Herikurniawan; Sinto, Robert; Singh, Gurmeet; Nainggolan, Leonard; Nelwan, Erni J; Chen, Lie Khie; Widhani, Alvina; Wijaya, Edwin; Wicaksana, Bramantya; Maksum, Maradewi; Annisa, Firda; Jasirwan, Chyntia OM; Yunihastuti, Evy
Jurnal Penyakit Dalam Indonesia Vol. 7, No. 1
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Perubahan Perilaku Penggunaan Alat Pelindung Diri (APD) Pasca Terinfeksi COVID-19 pada Dokter di Indonesia: Sebuah Survei Nasional pada Awal Pandemi Herikurniawan, Herikurniawan; Yunihastuti, Evy; Syam, Ari F; Soemarko, Dewi Sumaryani Sumaryani; Wiraguna, Andrian
Jurnal Penyakit Dalam Indonesia Vol. 10, No. 2
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Introduction. Doctors have greater risk of acquiring COVID-19 due to occupational exposure. Personal protective equipment (PPE) is an essential factor in reducing COVID-19 transmission. We aimed to evaluate the behavior changes of PPE usage among doctors in Indonesia before and after getting COVID-19 infection in early pandemic. Methods. This was a descriptive online survey with cross-sectional design. This survey was conducted from October-December 2020 among Indonesian doctors who were COVID-19 survivors. Results. A total of 389 doctors who survived COVID-19 infection across Indonesia were included in the final analysis. Most participants were general practitioners and residents (69.2%) with a median age of 40 (22-28) years. After being infected, there was an improvement in the use of N95 respirator masks in isolation rooms (always: 80.9% from 70.2%; sometimes: 13.2% from 15.8%). An improvement in the use of other PPE before and after being infected with COVID-19 was also shown by the use of other PPE such as headcap (93.9% from 83.3%), face shield (90.4% from 83.3%), goggles (70.2% from 62.3%), gown (61.4% from 53.6%), hazmat suit (88.6% from 81.6%), boots (82.5% from 71.1%), and gloves (91.3% from 86.8%). Similar results were also shown in the use of PPE in other non-isolation rooms. Conclusion. After recovering from COVID-19 infection, these doctors showed an increase usage of adequate PPE both while on duty in isolation and non-isolation rooms.
Ventilasi Noninvasif pada Obstructive Sleep Apnea dan Obesity Hypoventilation Syndrome Herikurniawan, Herikurniawan; Audrey, Joanna; Adelya, Firina
Jurnal Penyakit Dalam Indonesia Vol. 11, No. 3
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Chronic respiratory disease such as obstructive sleep apnea (OSA) and obesity-hypoventilation syndrome (OHS) remain are respiratory sleeping disorder that gradually affect quality of life. Comprehensive treatment such as the use of non-invasive ventilation (NIV) is a method adopted to improve the patient’s quality of life. The correct choice of NIV mode, mask and titration methods will provide optimal therapeutic effects to the patient. This article review lays out an update on the use of non-invasive ventilation as the treatment of OSA and OHS.
Faktor-Faktor yang Berhubungan dengan Infeksi Laten Tuberkulosis pada Pasien Lupus Eritematosus Sistemik dan Artritis Reumatoid di RSUPN Dr. Cipto Mangunkusumo Musthofa, Fahmi Adnan; Herikurniawan, Herikurniawan; Pitoyo, Ceva Wicaksono; Widhani, Alvina; Syam, Ari Fahrial; Putranto, Rudi; Nasution, Sally Aman; Dwimartutie, Noto; Wibowo, Suryo Anggoro Kusumo
Jurnal Penyakit Dalam Indonesia
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Introduction. Patients with systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA) are at increased risk of latent tuberculosis infection (LTBI) because of immune dysregulation and prolonged immunosuppressive therapy. However, data on the prevalence and factors associated with LTBI among patients with autoimmune diseases in Indonesia remain limited. This study aimed to identify factors associated with LTBI among adult outpatients with SLE and RA at Dr. Cipto Mangunkusumo National General Hospital (RSCM). Methods. This analytic cross-sectional study was conducted at the Allergy-Immunology and Rheumatology Outpatient Clinic of RSCM from November 2025 to July 2026. Data were obtained through structured interviews and medical record reviews. LTBI was assessed using the tuberculin skin test (TST) with 0.1 mL purified protein derivative administered intradermally, and induration was measured after 48–72 hours. Multivariable analysis was performed using binary logistic regression with autoimmune disease type included as a clinical covariate. Two sensitivity analyses were conducted using different disease activity dichotomization models. Results. A total of 193 patients were included, comprising 132 patients with SLE (68.4%) and 61 with RA (31.6%). The prevalence of LTBI was 10.9% (95% CI, 7.2–16.1%). In the bivariate analysis, three variables met the criterion for multivariable analysis (p Conclusions. The prevalence of LTBI among outpatients with SLE and RA at RSCM was 10.9%. Although no independent factor reached statistical significance, disease activity and a history of close contact with tuberculosis consistently demonstrated clinically relevant positive associations with LTBI, warranting further investigation in larger prospective studies.
Faktor Risiko yang Berhubungan dengan Kejadian Gangguan Ginjal Akut pada Pasien COVID-19 di RSUPN Dr. Cipto Mangunkusumo Ikapratiwi, Radita; Nugroho, Pringgodigdo; Herikurniawan, Herikurniawan; Widhani, Alvina; Rinaldi, Ikhwan; Yamin, Muhammad; Ariane, Anna; Wafa, Syahidatul
Jurnal Penyakit Dalam Indonesia
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Introduction. Coronavirus disease 2019 (COVID-19) affects not only the respiratory system but also cause systemic complications, including acute kidney injury (AKI). The occurrence of AKI in COVID-19 patients is associated with increased mortality and morbidity. Global data indicate that AKI occurs in approximately 4,3–50,6% of hospitalized COVID-19 patients, particularly among the elderly and those with comorbidities. This acute impairment of kidney function may worsen the course of the disease and increase the burden on hospital services. This study aimed to determine the proportion of AKI and analyze the risk factors associated with the occurrence of AKI in COVID-19 patients at Dr. Cipto Mangunkusumo National General Hospital. Methods. This was an analytical observational study with a cross-sectional design using medical records of adult COVID-19 patients admitted to Dr. Cipto Mangunkusumo National General Hospital from April 2020 to March 2022. Samples were selected using a consecutive sampling method. The main outcome assessed was the occurrence of acute kidney injury and its association with age, sex, hypertension, diabetes, cardiovascular disease, obesity, severity of COVID-19, procalcitonin levels, CRP levels, and D-dimer levels. Data were analyzed using univariate, bivariate, and multivariate logistic regression analyses. Results. Out of 422 subjects analyzed, 113 patients (26.8%) developed AKI. Multivariate analysis showed that age ≥60 years (PR = 2.18; 95% CI: 1.26–3.77; p = 0.005), hypertension (PR = 1.88; 95% CI: 1.06–3.37; p = 0.03), elevated procalcitonin levels (PR = 4.48; 95% CI: 2.56–7.84; p < 0.001), cardiovascular disease (PR = 4.84; 95% CI: 2.57–9.11; p < 0.001), and obesity (PR = 2.52; 95% CI: 1.46–4.33; p = 0.001) were significantly associated with the occurrence of AKI. Conclusions. The proportion of AKI among COVID-19 patients at Dr. Cipto Mangunkusumo National General Hospital was relatively high. Age > 60 years, hypertension, elevated procalcitonin > 0,18, cardiovascular disease, and obesity are risk factors associated with the occurrence of AKI in COVID-19 patients.
Co-Authors Adelya, Firina Adityo Susilo, Adityo Alvina Widhani, Alvina Anna Ariane, Anna Annisa, Firda Ari F Syam Ari Fahrial Syam Audrey, Joanna C. Martin Rumende, C. Martin Ceva W. Pitoyo Dewi Sumaryani Soemarko Djoko Hardiman Djoko Hardiman Edwin Wijaya, Edwin Erni J. Nelwan, Erni J. Evy Yunihastuti Gurmeet Singh Ikapratiwi, Radita Ikhwan Rinaldi Jasirwan, Chyntia OM Khie Chen Leonard Nainggolan Maksum, Maradewi Mira Yulianti, Mira Muhammad Yamin Musthofa, Fahmi Adnan Noto Dwimartutie Pringgodigdo Nugroho, Pringgodigdo Robert Sinto Rudi Putranto Sally Aman Nasution Syahidatul Wafa, Syahidatul Wibowo, Suryo Anggoro Kusumo Wicaksana, Bramantya Wiraguna, Andrian