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All Journal SANITAS: Jurnal Teknologi dan Seni Kesehatan Jurnal Riset Kefarmasian Indonesia
Susanti, Yanthy
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Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health

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Physical Properties and Preference Levels Testing of Perfume Formulation From Medang Pirawas Leaf’s Essential Oil (Litsea Elliptica Blume) Handayani, Indri Astuti; Syahputra, Guritno; Rismana, Eriawan; Susanti, Yanthy
SANITAS: Jurnal Teknologi dan Seni Kesehatan Vol 16 No 1 (2025): SANITAS Volume 16 Nomor 1 Tahun 2025
Publisher : Politeknik Kesehatan Kemenkes Jakarta II

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36525/sanitas.2025.540

Abstract

The use of perfume is a necessity in daily life for many individuals. Perfume compositions rely on essential oils, categorized into top, middle, and base notes, which differ based on the volatility and specific gravity of the oils used. The essential oil of medang pirawas leaves (Litsea elliptica Blume), rich in terpineol (23.36%), is known for its distinct aroma and is used in perfumes. This study aimed to evaluate the physical properties and preference levels of perfume formulations made with Litsea elliptica essential oil. The oil was extracted via steam distillation and analyzed using GC-MS. A base formula (F0) combined Litsea elliptica and lavender essential oils, with variations incorporating sweet orange (F1), lemon (F2), lime (F3), and bergamot (F4) essential oils. Physical tests included specific gravity (0.7–1.2), stain tests on tissue, HVS, and filter paper, and aroma longevity (>240 minutes). Preference tests were conducted with 30 respondents. All formulations met specific gravity standards and showed no staining. F4 was the only formulation that satisfied aroma longevity requirements, while F1 was the most preferred. Statistical analysis using SPSS 26 revealed data normality for specific gravity and aroma longevity. Paired Sample T-Tests showed significant effects of citrus essential oils on specific gravity (p = 0.01) but not on aroma longevity (p = 0.638). In conclusion, the formulations met physical property standards beside aroma longevity which only F4 excelled at and F1 being the most favored by respondents. The addition of citrus essential oils had a significant impact on the specific gravity, but not for the aroma longevity.
PROFIL JUMLAH NEOVASKULARISASI LUKA MENCIT HIPERGLIKEMIK YANG DIBERIKAN GEL EKSTRAK BUAH OKRA (Abelmoschus esculentus L.) Chandra, Pra Panca Bayu; Lisnawati, Nia; Susanti, Yanthy
Jurnal Riset Kefarmasian Indonesia Vol. 6 No. 2 (2024): Jurnal Riset Kefarmasian Indonesia
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33759/jrki.v6i2.523

Abstract

This study aimed to examine the gel activity of okra fruit extract (Abelmoschus esculentus L.) in mice with hyperglycemic conditions based on histopathological indicator parameters, namely the amount of neovascularization. Mus musculus strain male mice were hyperglycemic with STZ at a dose of 0.06 mg/gBW. Mice were divided into 8 groups (n=6). Group 1 (Non-DM Control), Group 2 (DM Control), Groups 3 to 8 (Test). The dose of glibenclamide was 5 mg/KgBW, the dose of okra fruit extract was 400 mg/KgBW and the dose of CMC Na was 5 mL/KgBW. Therapy was given once a day (oral and topical) for 15 days of therapy which was seen on days 0, 5, 11 and 15. The results of the study showed an increase in the number of neovascularizations on the 15th day of therapy in the test group compared to the control group. Administration of a combination of topical okra fruit extract gel with okra fruit extract orally for 15 days of therapy was able to increase the amount of neovascularization compared to administration without the combination or only orally. Administration of a combination of topical gel and oral okra fruit extract accelerated the wound healing process in hyperglycemic mice compared to non-combination administration. Management of fasting blood glucose levels has an effect on the success of the diabetic wound healing process.  
Co-Authors Chandra, Pra Panca Bayu Eriawan Rismana Handayani, Indri Astuti Lisnawati, Nia SYAHPUTRA, GURITNO