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All Journal JURNAL PENGABDI Jurnal Farmasi Medica (Pharmacy Medical Journal) PMJ PROMOTOR Jurnal Riset Kefarmasian Indonesia Jurnal Buana Farma Binawan Student Journal Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan

Lisnawati, Nia

Unknown Affiliation

Author-ID : 1383477

Biochemistry, Genetics & Molecular Biology Chemistry Control & Systems Engineering Decision Sciences, Operations Research & Management Energy Health Professions Immunology & microbiology Mechanical Engineering Medicine & Pharmacology Nursing Public Health Social Sciences

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PERBANDINGAN UJI DAYA HAMBAT ANTARA EKSTRAK AKAR BELUNTAS DENGAN KULIT BUAH MAHKOTA DEWA TERHADAP PERTUMBUHAN BAKTERI E.COLI Agustina, Ika; Efrilia, Mega; Lisnawati, Nia
Jurnal Riset Kefarmasian Indonesia Vol 1 No 3 (2019): Jurnal Riset Kefarmasian Indonesia
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

When this has been much studied extracts of herbs or traditional medicines, among other crops beluntas (Pluchea indica Less) and mahkota dewa (Phaleria macrocarpa (Scheff.) Boerl.) As an antibacterial. Previous research has suggested that the rind of the gods crown and root beluntas known to have antibacterial activity, but please be more certain with the same methods and evaluation in testing the antibacterial activity of both plants against bacteria Escherichia coli. Are both these plants have a vigorous activity the same or different from one another. The method used to test the antibacterial activity is using the disc. The results showed beluntas root extract has inhibitory activity against Escherichia coli was higher than fruit skin extracts gods crown with a minimum concentration of 6%, while the fruit skin extracts crowns a new god looks at a concentration of 12%. Based on the paired t-test showed that there is a significant difference between the antibacterial activity of root extracts beluntas with fruit leather crown god.

PENENTUAN NILAI SPF EKSTRAK ETIL ASETAT DAUN MANGGA GEDONG MENGGUNAKAN SPEKTROFOTOMETRI UV - VIS Lisnawati, Nia; N.U, M Fathan; Nurlitasari, Dwi
Jurnal Riset Kefarmasian Indonesia Vol 1 No 2 (2019): Jurnal Riset Kefarmasian Indonesia
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

One way that is done to reduce the negative impact of sunlight is by using sunscreen. Sunscreen can protect the skin by spreading sunlight or absorbing sunlight radiation energy that is about the skin. Phenolic compounds especially flavonoid groups have the potential as a sunscreen because of the chromophore group (single conjugated double bond) capable of absorbing UV light both UV A and UV B, thus reducing the intensity of the skin. Flavonoids have three properties of photoprotektor that is UV absorption, antioxidant properties, and modulate some DNA signaling pathways. The potential of sunscreen can be expressed with Sun Protection Factor (SPF). SPF is designated as UV protection B and is not specifically intended to resist UV A and UV C. The purpose of this research is to know the value of SPF (Sun Protection Factor) of ethyl acetate extract of mango gedong leaves using UV-Vis spectrophotometry. Simplicia gedong mango leaves were extracted using ethyl acetate solvent by reflux. Gedong mango leaf extract identified flavonoid compound using 10% NaOH and H2SO4 (concentrated). Determination of SPF (Sun Protection Factor) value of med gedong leaf extract using UV-Vis spectrophotometry method. The concentration of ethyl acetate extract of mango gedong leaves used was 120 ppm, 240 ppm and 360 ppm. The SPF (Sun Protection Factor) values were analyzed using Mansur method. The result of identification of flavonoid compound showed that the extract of ethyl acetate of mango gedong leaves positively contain flavonoids, while the result of SPF (Sun Protection Factor) extract of ethyl acetate of mango gedong leaves was 5,556; 16,675 and 22,243. The SPF (Sun Protection Factor) extract of 5,556 muddy ethyl acetate leaves including moderate protection type, 16,675 and 22,243 including ultra-protection type when tested using UV-Vis spectrophotometry by Mansur method

FORMULASI GEL HAND SANITIZER EKSTRAK DAUN BELIMBING WULUH (Averrhoa bilimbi L.) Prayoga, Tria; Agustina, Ika; Lisnawati, Nia; Robby, Rohima; Hidayah, Nurul
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 9 No 1 (2024): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jiis.v9i1.1860

In an effort to counteract skin irritation due to repeated use of alcohol-based hand sanitizers, there is increasing interest in non-alcoholic alternatives incorporating natural antibacterial ingredients. This study focuses on developing a hand sanitizer gel utilizing ethanol extract from Averrhoa bilimbi L. leaves as an antibacterial agent, evaluating the effect of Carbopol 940 concentration on product characteristics. The aimed to develop a hand sanitizer gel that leverages the antibacterial properties of Averrhoa bilimbi L. leaf ethanol extract, by testing the effects of different Carbopol 940 concentrations (0.4%, 0.5%, and 0.6%) on product characteristics. The methods used included organoleptic, homogeneity, viscosity, and pH tests, with data processing using one-way ANOVA and Tukey HSD. Tye results of Organoleptic and homogeneity testing of all gel formulas on a weekly basis revealed consistent characteristics, with a yellow-brown color and a distinctive aroma characteristic of the Averrhoa bilimbi L. leaf extract. Furthermore, results showed that viscosity increased with the concentration of Carbopol 940, with the 0.6% formulation achieving the highest stability. However, all formulations had a pH range of 6.49 to 6.85, above the ideal skin range of 4.5–6.5. Quantitatively, significant differences in viscosity among the formulations were observed, while pH variations were not significant. The conclusion of the study confirmed that the Carbopol 940 concentration significantly affect viscosity, but further adjustments are needed to optimize the gel's pH to meet skin standards and enhance efficacy as a hygiene product.

IDENTIFIKASI CEMARAN LOGAM BERAT DALAM EKSTRAK ETANOL 70% BUAH OKRA (Abelmoschus esculentus L.): IDENTIFIKASI CEMARAN LOGAM BERAT DALAM EKSTRAK ETANOL 70% BUAH OKRA (Abelmoschus esculentus L.) CHANDRA, PRA; Efrilia, Mega; Prayoga, Tria; Lisnawati, Nia
Jurnal Farmasi Medica/Pharmacy Medical Journal (PMJ) Vol. 7 No. 1 (2024): Volume 7, No 1, Tahun 2024
Publisher : Sam Ratulangi University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35799/pmj.v7i1.54951

Okra fruit (Abelmoschus esculentus L.) is a natural ingredient that can be developed as a raw material for natural-based medicines. The phytochemical compounds contained in okra fruit are flavonoids, alkaloids, saponins, tannins, triterpenoids, coumarins, phenolics, glycosides. steroids and alkaloids, α-cellulose, hemicellulose, lignin, components. Okra fruit with varying secondary metabolite content produces positive effects on the potential pharmacological activity of okra fruit. The potential pharmacological activity of okra fruit is as antidiabetic, hypolipidemic, antioxidant, antimicrobial, anticancer, wound healing, hepatoprotective, immunomodulatory, neuroprotective and gastroprotective in addition to cardioprotective activity. Extracts must meet extract quality parameters, one of which is non-specific parameters for heavy metal contamination. This research aims to determine the heavy metal contamination content of Lead (Pb), Cadnium (Cd) and Arsenic (As) contained in the 70% ethanol extract of okra fruit. The okra fruit extraction process was carried out by maceration with 70% ethanol solvent. Determination of heavy metal content using an atomic absorption spectrophotometer instrument. The research results showed that the 70% ethanol extract of okra fruit did not contain Lead (Pb), Cadnium (Cd) and Arsenic (As). Keywords: Okra fruit, Abelmoschus esculentus, Heavy Metal Contamination

Standarisasi Simplisia Daun Salam (Syzygium polyanthum (Wight.) Walp) Berdasarkan Beberapa Parameter Spesifik dan Non Spesifik: Standardization of Bay Leaf Simplicia (Syzygium polyanthum (Wight.) Walp) Based on Several Specific and Non-Specific Parameters Panca, Pra Panca Bayu Chandra; Lisnawati, Nia
Binawan Student Journal Vol. 6 No. 3 (2024)
Publisher : Direktorat Penelitian, Pengabdian Masyarakat, Dan Kerjasama Universitas Binawan (DPPMK Universitas Binawan)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54771/8ft48z62

Daun Salam (Syzygium polyanthum (Wight.) Walp) dimanfaatkan sebagai rempah dan obat herbal yang semakin meluas karena mudah diperoleh dan harganya relatif murah. Tujuan penelitian ini melakukan standarisasi simplisia daun salam berdasarkan beberapa parameter spesifik dan non spesifik. Daun salam segar diproses hingga menjadi serbuk simplisia, kemudian dilakukan pengujian mutu. Hasil penelitian menunjukkan kadar bahan organik asing simplisia yaitu 2,59% dengan derajat halus simplisia 4/18 yaitu melewati ayakan mesh nomor 4 sebesar 100% dan ayakan mesh nomor 18 sebesar 92%. Serbuk simplisia daun salam memiliki makroskopis helaian daun tunggal, bertangkai pendek, pangkal daun lonjong, tepi daun rata. Serbuk simplisia daun salam memiliki mikroskopis kristal kalsium oksalat, epidermis, sklerenkim, unsur xilem noktah. Kadar senyawa yang larut dalam pelarut air dan etanol adalah masing-masing sebesar 6,50 ± 1,27% dan 11,49 ± 0,31%. Parameter non spesifik terdiri dari susut pengeringan, kadar air, bobot jenis, kadar abu total, kadar abu larut air serta kadar abu tidak larut asam masing-masing memberikan hasil susut pengeringan adalah 2,63 ± 0,56%, kadar air adalah 6,27 ± 1,93%, bobot jenis adalah 0,8286 ± 0,0109 g/mL, kadar abu total adalah 4,07 ± 0,24%, kadar abu larut air adalah 2,86 ± 0,51% serta kadar abu tidak larut asam adalah 5,44 ± 0,45%.

Pelatihan Pembuatan Wedang Uwuh Untuk Meningkatkan Pemanfaatan Imunomodulator Tumbuhan Obat di Masyarakat Lisnawati, Nia; Rismana, Eriawan
Jurnal Pengabdi Vol 8, No 1 (2025): April 2025
Publisher : Universitas Tanjungpura

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26418/jplp2km.v8i1.84926

Musim pancaroba, yang merupakan periode peralihan antara musim hujan dan kemarau, sering menimbulkan tantangan cuaca ekstrem di Indonesia, dan dapat menyebabkan penurunan imunitas tubuh. Jahe merah, yang dikenal dengan nama ilmiah Zingiber officinale var rubrum memiliki sifat sebagai imunomodulator dan dapat dijadikan minuman tradisional yang kaya akan manfaat kesehatan. Wedang uwuh adalah minuman herbal yang terbuat dari campuran rempah-rempah, termasuk daun, batang, ranting, dan rimpang. Dalam bahasa Jawa, “wedang” berarti minuman yang diseduh, sementara “uwuh” mengacu pada bahan-bahan seperti sampah dedaunan yang dikumpulkan. Wedang uwuh biasanya disajikan dalam keadaan panas atau hangat, memiliki rasa manis dan pedas, serta berwarna merah cerah dengan aroma harum. Pengabdian masyarakat ini bertujuan untuk meningkatkan pengetahuan dan keterampilan warga dalam membuat minuman wedang uwuh, serta memahami pentingnya meningkatkan daya tahan tubuh melalui minuman herbal. Metode yang digunakan sosialisasi dan demonstrasi pembuatan minuman uwuh bersama warga pengurus PKK RW.004 Kelurahan Klender. Hasil ini menunjukan warga sangat antusias mengikuti kegiatan tersebut, ada sebagian masyarakat yang tertarik memanfaatkan tanaman lokal untuk pembuatan jamu, dan seluruh warga dapat memahami cara membuat minuman atau jamu sehat yang berbahan dasar tanaman lokal. Kesimpulannya, kegiatan pengabdian masyarakat mengenai pemanfaatan tumbuhan obat yang di olah menjadi jamu tradisional berjalan lancar. Masyarakat sangat antusias dan masyarakat mengetahui cara membuat minuman sehat atau Jamu. Sosialisasi ini diharapkan dapat meningkatkan kemampuan masyarakat dalam memahami cara produksi tanaman obat dengan baik dan benar.

ANALISIS STRATEGI PELAKSANAAN PENEMUAN DAN TATALAKSANA PNEUMONIA PADA BALITA DI PUSKESMAS BOGOR UTARA TAHUN 2018 Lisnawati, Nia; Khodijah Parinduri, Siti; Syari, Wirda
PROMOTOR Vol 3 No 5 (2020)
Publisher : Fakultas Ilmu Kesehatan, Universitas Ibn Khaldun, Bogor

Pelaksanaan penemuan dan tatalaksana pneumonia balita merupakan strategi untuk pengendalian pneumonia balita dengan tujuan menemukan sedini mungkin dan mengobati sampai sembuh sehingga penyakit tidak memberat dan menyebabkan kematian balita. Tujuan penelitian ini adalah untuk menganalisis strategi pelaksanaan penemuan dan tatalaksana pneumonia balita di wilayah kerja Puskesmas Bogor Utara. Desain studi yang digunakan adalah deskriptif kualitatif dengan pendekatan kasus. Teknik yang dilakukan dalam pengumpulan data yaitu wawancara mendalam dan observasi dengan waktu penelitian pada bulan Mei-Juni 2019. Hasil penelitian pelaksanaan tatalaksana pneumonia balita di Puskesmas Bogor Utara belum maksimalnya pelaksanaan konseling ibu, tindak lanjut pneumonia balita, pencatatan dan pelaporan, evaluasi, serta sosialisasi kepada masyarakat tentang pneumonia balita serta bahayanya jika tidak segera ditangani.

AKTIVITAS ANTIJAMUR EKSTRAK ETANOL DAUN KARI TERHADAP Candida albicans ATCC 14053 Sari, Putri Eka; Chandra, Pra Panca Bayu; Lisnawati, Nia; Ami, Neng
Jurnal Buana Farma Vol. 5 No. 2 (2025): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v5i2.1400

Medicinal plants are recognized as valuable sources of secondary metabolites with therapeutic potential. Candidiasis caused by Candida albicans is a common health problem in tropical regions. The prolonged use of synthetic antifungal agents may lead to resistance, highlighting the need for effective natural alternatives. Curry leaves (Murraya koenigii (L) Spreng) are known to contain flavonoids and alkaloids with potential antifungal activity. This study aimed to evaluate the antifungal activity of the 96% ethanol extract of curry leaves against Candida albicans ATCC 14503. The extract was prepared by maceration using 96% ethanol as the solvent. Phytochemical screening revealed the presence of flavonoids and saponins. The antifungal activity was tested using the disc diffusion method at concentrations of 6,25%, 12,5%, 25%, and 50%. Ketoconazole was used as positive control, while 96% ethanol served as a negative control. The test was performed in triplicate, and the inhibition zones were measured and averaged. The results showed that the 96% ethanol extract of curry leaves at all tested concentrations did not exhibited antifungal activity against C. albicans as indicated by the absence of inhibition zones on the media. It can be concluded that the extract, under the given conditions, was not effective in inhibiting fungal growth. This suggests that the extraction method and tested concentrations may not have been sufficient to isolate or concentrate the active compounds. Further studies using alternative extraction techniques, higher concentrations or isolated compounds are needed to better evaluate the antifungal potential of M. koenigii.

Co-Authors Ami, Neng CHANDRA, PRA Chandra, Pra Panca Bayu Efrilia, Mega Eriawan Rismana ika agustina N.U, M Fathan Nurlitasari, Dwi NURUL HIDAYAH Panca, Pra Panca Bayu Chandra Prayoga, Tria PUTRI EKA SARI, PUTRI EKA Robby, Rohima Siti Khodijah Parinduri Wirda Syari

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