Mariani Santosa, Mariani
Department Of Physiology, School Of Medicine And Health Sciences, Atma Jaya Catholic University Of Indonesia, North Jakarta, Indonesia

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ATROPINE 0.01% AS A POTENTIAL MYOPIA PREVENTION IN CHILDREN WITH DOSAGE EFFECTIVITY COMPARISON: A LITERATURE REVIEW Ivan, Ignatius; Stella, Maureen Miracle; Santosa, Mariani
Jurnal Kedokteran YARSI Vol 27, No 3 (2019): SEPTEMBER - DESEMBER 2019
Publisher : Lembaga Penelitian Universitas YARSI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (187.31 KB) | DOI: 10.33476/jky.v27i3.1114

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Myopia (long-sightedness) is one of the many problems of vision disorder occurring around the world and being 1 in 5 eye conditions that becoming a priority at the World Health Organization's Global Intitiative for the Elimination of Avoidable Blindness. Many methods of preventing myopia development have been sought. Atropine is an alkaloid derived herbal plant Atropa belladonna which acts as a muscarinic acetylcholine receptor antagonist that has a strong nonselective competitive affinity on the five types of muskarinic acetylcholine receptors (M1-M5) that weaken the muscles of the ciliary and iris and causes the reduction of accommodation and the occurrence of pupil dilation. Recent research found that with the use of low dose atropine (0.01%), in addition to the side effects inflicted more minimal, effectiveness in the long time period shows better results. Until now, the  mechanism of atropine is still experiencing debate whether working on an accommodating or non-accommodating pathway. But recent research suggests the possibility of working mechanism of this drug is through a non-accommodating pathway i.e. on GABAergic, dopaminergic as well as involving nitric oxide (NO) role to help inhibit the progression of myopia. In research and advanced scientific studies, it can be researched regarding the pathways of atropine mechanism and its advantages and disadvantages at any dose of atropine given to myopia sufferers using the latest literature sources.
Association between Stress and Tension-Type Headaches in Medical Students of the School of Medicine & Health Science, Atma Jaya University Callista Anastasya; Julia Rahadian Tanjung; Mariani Santosa
Journal of Urban Health Research Vol. 1 No. 2 (2023): Journal of Urban Health Research
Publisher : School of Medicine and Health Sciences, Atma Jaya Catholic University of Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25170/juhr.v1i2.4208

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Introduction: Stress is the body's response to threatening external stimuli. Many medical students experience stress. Stress that medical students share can be caused by learning demands, interpersonal problems, and other things. Even though stress is daily, excessive stress can also cause various health problems, including headaches. Headache is the most common neurological problem in the world. There are several types of headaches, one of which is tension headaches. However, the relationship between stress and headaches, especially tension-type headaches in medical students, has yet to be widely studied. Methods: This study is a cross-sectional analytic observational study, on 120 pre-clinical students (22 males, 98 females) aged 18-21 from the School of Medicine and Health Sciences, Atma Jaya Catholic University in Jakarta. The questionnaire used to measure the respondent's stress levels were the Depression Anxiety Stress Scale 42 (DASS-42) and Headache Screening Questionnaire (HSQ) to determine the respondent's headache. The data obtained were analyzed statistically using the Chi-square method, with a p-value <0.05. Results: Out of 120 students, 74.2% experienced stress within normal limits, while 9.2%, 10%, 5%, and 1.7% reported experiencing mild, moderate, severe, and very severe stress levels, respectively. 30.8% of students experienced tension-type headaches, and 69.2% of students did not. The result obtained from the chi-square bivariate test was p = 0.188. Conclusions: There is no association between stress and tension-type headaches in medical students of the School of Medicine & Health Science, Atma Jaya University.   Keywords: stress, tension-type headache, DASS-42, HSQ
Cervical Cancer Campaign: Correlation Between HPV Vaccine and Cervical Cancer Knowledge with HPV Vaccination Rate Mariani Santosa; Ashley Karin Anjaya; Veronica Dwi Jani Juliawati; Robi Irawan; Yuliana
Journal of Urban Health Research Vol. 1 No. 3 (2023): Journal of Urban Health Research
Publisher : School of Medicine and Health Sciences, Atma Jaya Catholic University of Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25170/juhr.v1i3.4463

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Introduction: Cervical cancer ranks second for the highest cancer cases in Indonesia. The main cause is recurring HPV infection. HPV infection commonly occurs when transmission by skin-to-skin contact or skin to mucosa contact is enough to spread it. One prevention effort is HPV vaccination, but there are still obstacles such as a lack of education and expensive prices. Methods: This study is an analytic cross-sectional study. Data was collected from February through March of 2023 gathering a total of 121 respondents. Questionnaires are used for data collection with 10 questions concerning cervical cancer and 11 questions regarding HPV vaccine knowledge. The Fisher exact probability test was used as bivariate analysis. Results: This study shows that students of the Faculty of Medicine and Health Sciences at Atma Jaya Catholic University of Indonesia have great knowledge regarding cervical cancer, adequate and great knowledge concerning the HPV vaccine with the majority reporting not being vaccinated (69,4%). Bivariate analysis shows no significant correlation between cervical cancer and HPV vaccine knowledge with HPV vaccination rate (p = 0,499 and p = 0,808). Conclusions: There is no significant correlation between cervical cancer and HPV vaccine knowledge with HPV vaccination rate among preclinical students of Faculty of Medicine and Health Sciences at Atma Jaya Catholic University of Indonesia.
Prevalence of E-cigarette Users Students and Determinant Factors Affecting Their Use Behavior Zita Arieselia; Lonah Lonah; Linawati Hananta; Margareta Amelia; Fenny Mariska; Via Dolorosa Halilintar; Mariani Santosa; Meiliyana Wijaya; Rita Dewi; Jonny Setiawan; Monalisa Heryani
Bahasa Indonesia Vol 22 No 2 (2023): Damianus Journal of Medicine
Publisher : Atma Jaya Catholic University of Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25170/djm.v22i2.3820

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Pendahuluan: Prevalensi pengguna rokok tembakau pada remaja di Indonesia terus meningkat dari 7,2% pada tahun 2013 menjadi 9,1% pada tahun 2018, tingkat penggunaannya dianggap dapat dikurangi dengan menggunakan rokok elektrik. Namun sebenarnya rokok elektrik belum dapat disebut sebagai terapi berhenti merokok konvensional karena belum terdapat bukti yang cukup kuat dan dampak penggunaannya pada kesehatan yang tidak dapat dikesampingkan. Sementara itu, beberapa studi menunjukkan bahwa penggunaan rokok elektrik juga berdampak buruk bagi kesehatan. Tujuan penelitian ini adalah untuk mengetahui prevalensi pengguna dan faktor determinan yang memengaruhi perilaku penggunaan rokok elektrik pada mahasiswa. Metode: Studi ini merupakan penelitian kuantitatif dengan desain studi potong lintang atau cross sectional. Sampel yang digunakan sebanyak 410 orang dengan kriteria inklusi berupa mahasiswa aktif Unika Atma Jaya serta orang yang telah setuju untuk menjadi responden penelitian setelah membaca informed consent, dan kriteria eksklusi yaitu responden yang mengisi kuesioner dengan tidak lengkap. Perhitungan sampel dilakukan dengan metode proportional stratified random sampling. Pengambilan data responden menggunakan kuesioner secara daring melalui Google Forms. Analisis data menggunakan uji Chi Square dan Mann-Whitney.   Hasil: Prevalensi pengguna rokok elektrik pada mahasiswa sebesar 21,7%. Pada penelitian ini faktor yang berpengaruh pada keputusan penggunaan rokok elektrik adalah jenis kelamin (p<0,001), persepsi (p<0,001), tersedianya suplai (p<0,001), dukungan keluarga (p=0,002), dan dukungan teman (p<0,001). Simpulan: Tingginya tingkat penggunaan rokok elektrik pada mahasiswa menunjukkan perlunya informasi dan edukasi serta promosi kesehatan mengenai dampak merugikan dari penggunaan rokok elektrik.
Pengaruh tingkat aktivitas fisik terhadap derajat dismenorea primer pada wanita usia dewasa muda Irawan, Robi; Santosa, Mariani; Liezandi, Edgina
Bahasa Indonesia Vol 21 No 2 (2022): Damianus Journal of Medicine
Publisher : Atma Jaya Catholic University of Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25170/djm.v21i2.3461

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Pendahuluan: Dismenorea primer merupakan masalah ginekologis yang paling umum pada wanita dan seringkali menyebabkan gangguan pada aktivitas sehari-hari. Prevalensi dismenorea primer di Indonesia mencapai 54,89% dan paling banyak ditemukan pada usia produktif. Dismenorea dapat dipengaruhi oleh berbagai faktor, salah satunya adalah aktivitas fisik. Secara global, 84% wanita dinyatakan kurang melakukan aktivitas fisik. Tingginya prevalensi dismenorea primer dan persentase wanita yang kurang melakukan aktivitas fisik merupakan dasar ketertarikan dilakukannya penelitian ini. Penelitian ini bertujuan untuk melihat hubungan antara intensitas aktivitas fisik dengan derajat keparahan dismenorea primer. Metode: Penelitian ini merupakan sebuah studi analitik potong lintang. Pengambilan data dilakukan pada bulan Agustus 2020 dengan total 107 responden yang memiliki usia berkisar antara 17 hingga 22 tahun. Pengambilan data penelitian menggunakan Kuesioner Baecke untuk menilai intensitas aktivitas fisik dan Verbal Multidimensional Scoring System dan Visual Analog Scale untuk menentukan derajat dismenorea primer. Analisis bivariat hubungan intensitas aktivitas fisik dengan derajat keparahan dismenorea primer menggunakan uji korelasi Kendall’s Tau.  Hasil: Penelitian ini menunjukkan bahwa sebagian besar responden mengalami dismenorea primer derajat 1 (45,8%) dan memiliki tingkat intensitas aktivitas fisik sedang (58,9%). Analisis bivariat menunjukkan bahwa tidak terdapat hubungan yang bermakna antara intensitas aktivitas fisik dengan derajat keparahan dismenorea primer (p=0,290).                                                                             Simpulan: Tidak ada hubungan antara intensitas aktivitas fisik dengan derajat keparahan dismenorea primer.
Assessing the Correlation between Spicy Food Consumption and Dyspepsia Symptoms in Medical and Health Students at Atma Jaya Catholic University of Indonesia Lonah; Divara Ariesta Sekar Suryadi, Made; Arieselia, Zita; Vitria Kurniawan, Sandy; Hananta, Linawati; Setiawan, Jonny; Surjono, Edward; Santosa, Mariani; Ulina Margareta Situmorang, Evi; Fan, Tan Fei; Yuliana; Budiyanti, Ecie
Journal of Urban Health Research Vol. 2 No. 3 (2024): Journal of Urban Health Research
Publisher : School of Medicine and Health Sciences, Atma Jaya Catholic University of Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25170/juhr.v2i3.5463

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Introduction: The capsaicin (8-methyl-N-vanillyl-6-nonenamide) content in spicy foods can trigger irritation and increase gastric acid production, which potentially damages the stomach mucous layer by increasing chloric acid levels (HCl). It is known that dyspepsia has a variety of causes and one of them can be triggered by the consumption of irritating foods, such as spicy foods. Therefore, the research was conducted to determine whether there was a significant relationship between the consumption of spicy foods and the incidence of dyspepsia in students of the Faculty of Medicine and Health Sciences at the Atma Jaya Catholic University of Indonesia. Methods: This research method is an analytical observational study using cross-sectional methods. The main variables in this study were dyspepsia, measured using the Rome III questionnaire, and the frequency of spicy food consumption measured using the Food Frequency Questionnaire (FFQ). The sample consisted of 107 people randomly selected. The data was analyzed statistically using the Fischer Exact test. Results: This study showed that 56.1% of respondents frequently eat spicy foods, while the majority, as much as 95.3%, also have dyspepsia. There was a significant correlation between spicy eating habits and dyspepsia, with a p-value of 0.014 (p<0.05). Conclusion: The results showed a statistically significant relationship between spicy eating habits and dyspepsia, so it is recommended for students to reduce spicy food consumption as it can affect the onset of dyspepsia. Keywords: dyspepsia - spicy foods - stomach - Rome III questionnaire - food frequency questionnaire
Driving and Back Pain among Online Motorcyclist Transportation in Jakarta Tanjung, Julia Rahadian; Tan, Wanda Permata Prihastanti; Santosa, Mariani
Journal of Urban Health Research Vol. 2 No. 3 (2024): Journal of Urban Health Research
Publisher : School of Medicine and Health Sciences, Atma Jaya Catholic University of Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25170/juhr.v2i3.5587

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Introduction: Low Back Pain (LBP) is a musculoskeletal disorder in the form of pain in the lower back caused by various factors. One of the common factors is work. Work factors that can cause LBP are body position, posture, workplace design, repetition, duration of work, and work that forces labor. One of the risky jobs is being an online motorbike taxi driver (“Ojek”), one of Jakarta's most popular transportation types. By using an application to call, an online “Ojek” not only acts as a means of transporting people or goods but can also be used to buy goods and order food. The prolonged sitting position in static conditions and limited space to move around contribute to LBP in “Ojek” drivers. This study investigates the association between driving duration and LBP in “Ojek” drivers. Methods: This was an observational analytic study with a cross-sectional approach on 63 male online “Ojek” drivers aged 25-35 with normal BMI who met the inclusion and exclusion criteria. The study was conducted in the Central Jakarta area in November-December 2019. The sampling technique is accidental sampling. Duration of the driving questionnaire and Nordic Low Back Pain Questionnaire were used to gather the data. A bivariate analysis test was conducted with a chi-square statistical test with p ≤ 0,05. Results: Thirty-eight online ‘Ojek” drivers (60.32%) reported having LBP in the last 12 months. Bivariate analysis by chi-square statistical test found that the p-value equals 0.414 between driving duration and incidence. Conclusion: Driving duration is unrelated to the incidence of lower back pain. LBP is most common in drivers driving more than 8 hours daily. Keywords: driving duration - online drivers - low back pain - prolonged sitting - static condition
Hubungan Pengetahuan, Sikap, dan Perilaku Mengakses Situs Pornografi terhadap Nilai Akademis Pelajar SMA Kota Bogor Situmorang, Evi Ulina Margareta; Muhaji, J. Antonio; Pramono, Laurentius Aswin; Santosa, Mariani; Lonah; Nathaniel, Bryan
Jurnal Kedokteran Meditek Vol 30 No 2 (2024): MEI
Publisher : Fakultas Kedokteran Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/jkdoktmeditek.v30i2.2545

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Mayoritas siswa SMP dan SMA di kota Jakarta dan Banten telah terpapar konten pornografi dan ditemukan peningkatan akses internet, terutama situs pornografi dan game online, di masa pandemi COVID-19. Penelitian ini bertujuan untuk mengetahui hubungan antara pengetahuan, sikap, dan perilaku mengakses situs pornografi serta bermain game online terhadap nilai akademis pada pelajar SMA di kota Bogor di masa pandemi COVID-19. Penelitian ini menggunakan desain potong-lintang dengan menggunakan data kuesioner yang diambil menggunakan aplikasi Zoom. Penelitian dilakukan di SMA X di Bogor dan melibatkan 107 responden dan metode analisis dalam penelitian ini adalah uji Chi-Square. Variabel bebas penelitian ini adalah pengetahuan, sikap, dan perilaku pelajar SMA. Adapun variabel terikat dalam penelitian ini adalah nilai akademis. Hasil analisis menunjukkan bahwa tidak ada hubungan yang signifikan antara pengetahuan, sikap, dan perilaku pelajar SMA dalam mengakses situs pornografi dan bermain game online dengan nilai akademis dengan nilai p = 0,109; 0,869; 0,258 secara berurutan. Disimpulkan dalam penelitian ini bahwa tidak ada hubungan antara pengetahuan, sikap, dan perilaku mengakses situs pornografi serta bermain game online terhadap nilai akademis pada pelajar SMA di kota Bogor di masa pandemi COVID-19.
The Impact of Body Fat Percentage towards the Attention Aspect of the Cognitive Function in Pre-Clinical University Students of Atma Jaya Mariani Santosa; Alvin Edwin Wiyono; Robi Irawan
Sriwijaya Journal of Medicine Vol. 4 No. 2 (2021): Vol 4, No 2, 2021
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/sjm.v4i2.106

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In 2016, World Health Organization (WHO) predicts that 650 million adults aged 18 and more have obesity. Many research shows that obesity affects brain function and impairs the cognitive function of the brain. To understand whether body fat percentage has an impact on the attention aspect of the cognitive function in university students. This study is a cross-sectional study approach. The data was collected from August 2020 until March 2021 with a total of 72 respondents. The data was collected using the body fat percentage formula from the British Journal of Nutrition to assess body fat percentage and Stroop Test for attention. Kruskal-Wallis and spearman were used to assess the correlation between body fat percentage and attention. The result shows that body fat percentage affects the attention aspect of the cognitive function (p = 0.001, r = 0.71). In conclusion, based on 72 university students, it proves that body fat percentage has an impact on the attention aspect of the cognitive function. The impact that high body fat percentage does is lowering the attention aspect of the cognitive function.
The relationship between the degree of low back pain and concentration levels among RICCI Catholic High School Jakarta students during the COVID-19 pandemic Putu Radhya Kirana Karmanita; Heidy; Nelson Sudiyono; Mariani Santosa
Indonesian Journal of Biomedicine and Clinical Sciences Vol 57 No 2 (2025)
Publisher : Published by Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/inajbcs.v57i2.20200

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The COVID-19 pandemic has shifted most learning activities to an online format, leading to increased sitting time and a higher risk of low back pain (LBP). Low back pain can be a factor that causes changes in concentration during learning. This study aimed to evaluate the relationship between the degree of LBP and the level of learning concentration in high school students. It was a cross-sectional study conducted at RICCI Catholic High School Jakarta, involving students from grades 10, 11, and 12. Data were collected using a questionnaire that was distributed online with Google forms. The Chi-square method for data analysis was used with a significance level of 0.05. A total of 121 students participated in this study, with 66.9% did not experience LBP, 30.6% had LBP with a slight degree of pain, and 2.5% had LBP . There were no students with severe LBP. The results for low, moderate and high concentration levels were 8.3%, 70.2%, and 21.5%, respectively. The bivariate analysis between LBP and learning concentration level using was 0.062 (p>0.05). In conclusion, there is no significant relationship between the degree of LBP and the level of concentration in high school students.