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Journal : JURNAL FARMASIMED (JFM)

PENETAPAN KADAR VITAMIN C PADA KULIT PISANG (Musa paradisiaca) DENGAN METODE SPEKTROFOTOMETRI UV-VISIBLE TAHUN 2018 Pratiwi, Asti; Manurung, Ardita Febrianty; sumitra, Jhoti
Jurnal FARMASIMED (JFM) Vol 2 No 2 (2020): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v2i2.363

Abstract

Background: Vitamin C is a vitamin that is water soluble qnd one vitamin that are needed by the body. To meet the intake of vitamin C needed source of vitamin a derived from fruits, one of which is banana. Part of the banana , which is still rarely used is its skin. Banana peel is very beneficial for health however the situation is only considered as waste that has not been utilized well. This study aims to determine the levels of vitamin C on the skin of the banana (Musa paradisiaca) by the method of spectrofotometry uv-visible wavelength 224,5 nm. Method: This research use experimental with purely research stage comprise sample preparation, qualitative test, making the solution of the parent raw, quantitative test, determination of wavelength of maximum vitamin and creation of calibration surve. Result: Based on the research that has been done obtained the result of the qualitative test to prove the presence of high content of vitamin C contained in banana peels, with the highest level obtained in the skin of the plantain by 0,0253 mg/ml and the levels of the lowest on a banana peel the wax by 0,0172 ng/ml. Discussion: Levels of vitamin C on the skin of the banana barangan of 0, 0219 mg/ml, sample a banana skin banten by 0, 0173 mg/ml, sample a banana peel wax by 0, 0172 mg/ml and sample the skin of plantain by 0, 0253 mg/ml.
EFFECTIVENNES OF SKIN EXTRACT OF POMEGRANATE (PUNICA GRANATUM L) AND OLIVE OIL AS LIP MOISTURIZING (LIP BALM) Sumitra, Jhoti
Jurnal FARMASIMED (JFM) Vol 4 No 2 (2022): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v4i2.1006

Abstract

Lip balm preparatios can contain active ingredients that aim to protect the lips from extreme weather and hot sun. The active ingredient added to lip balm preparations can use natural ingredients from nature or pure chemical compounds. Natural ingredients have the advantage of having minimal side effects for long-term use. So that natural ingredients are currently the prima donna in the formulation of cosmetic preparations, including lip balm preparations. The properties of pomegranate skin protect and repair lips in lip balm preparations. pomegranate peel (Punica granatum L.) as a natural colorant and utilizes olive oil (Olive oil) as an emollient or moisturizer formulated in lip balm preparations. The results showed that all homogeneous lip balm preparations had a pH of 5.6-6.1 and were stable for 12 weeks of storage. Lip balm preparations with 10% concentration of pomegranate peel extract can provide the best lip moisturizing effect to restore lip skin once a week after application for 4 weeks. All preparations of pomegranate peel extract lip balm do not irritate the skin.
ANTI-INFLAMMATORY EXCITIVITY TEST OF SINTRONG LEAF ETHANOL EXTRACT (Crassocephalum crepidiodes) ON MALE WHITE MICE Sumitra, Jhoti; Pasaribu, Esra Navita Rida
Jurnal FARMASIMED (JFM) Vol 5 No 1 (2022): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v5i1.1279

Abstract

Sintrong (Crassocephalum crepidioides) merupakan kelompok tanaman dengan batang lunak yang dipercaya bisa mengobati berbagai macam penyakit, seperti gangguan pencernaan, sakit kepala, sakit perut, mengobati luka, antelmetik, antiinflamasi, antidiabetes, dan antimalaria. Daun sintrong mengandung senyawa metabolit sekunder yaitu flavonoid yang diketahui memiliki aktivitas sebagai antiinflamasi. Penelitian ini bertujuan untuk mengetahui efektivitas antiiinflmasi ekstrak etanol daun sintrong (Crassocephalum crepidiodes) terhadap mencit putih jantan. Penelitian ini adalah penelitian eksperimental yang dibagi menjadi 5 kelompok yaitu Natrium Diklofenak, kontrol negatif Na-Cmc 0,5 %, dan EEDS dosis 100, 200 dan 300 mg/kgBB. Data hasil penelitian dihitung persen radang dan persen inhibisi radang. Data dianalisis secara statistik menggunakan metode Anova dan dilanjutkan dengan uji Duncan. Hasil penelitian menunjukkan bahwa EEDS 300 mg/kgBB memiliki inhibisi radang paling besar dibanding ekstrak 100 dan 200 mg/kgBB. Hasil uji one way Anova menunjukkan adanya perbedaan yang signifikan (P>0,05) antar kelompok perlakuan. Hasil uji Duncan menunjukkan kelompok yang memberikan efektivitas antiinflamasi terbaik adalah kontrol positif dan EEDS 300 mg/kgBB.