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All Journal JURNAL FARMASIMED (JFM) Mejuajua Jurnal Pengmas Kestra (JPK) Medistra Medical Journal (MMJ)
Pranata, Chandra
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Humanities Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Medicine & Pharmacology Nursing Public Health Other

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Socialization of The Use of Melinjo Leaf Ethanol Extract (Gnetum gnemon L.) on Growth Salmonella typhi Bacteria Syarifuddin, Aminah; Pranata, Chandra; Boru Situmorang, Novidawati; Octora, Debi Dinha; Ramadhani, Lili
JURNAL PENGMAS KESTRA (JPK) Vol. 3 No. 1 (2023): Jurnal Pengmas Kestra (JPK)
Publisher : Lembaga Penelitian dan Pengabdian Kepada Masyarakat (LP2M) Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jpk.v3i1.1149

Abstract

Gnetum gnemon L. has antibacterial activity against Salmonella typhi because it contains flavonoids, saponins, tannins, alkaloids, and steroids. Where these compounds play an important role as an antibacterial. The purpose of this service is to provide information to the public regarding the benefits of melinjo leaves which can act as an antibacterial agent. This service activity is carried out in the form of socialization using lecture, question and answer, and demonstration methods. The number of participants in this community service activity was 20 pharmacists at Grandmed Lubuk Pakam Hospital. Based on the results of the PkM activities carried out, it can be stated that there has been an increase in public knowledge regarding the efficacy of melinjo leaves as an antibacterial substance. This can be proven by the increase in post-test scores when compared to pre-test scores. The average increase in the knowledge of PkM participants was 21.5. On the other hand, the highest post-test score obtained was 85, while the lowest post-test score was 60. Meanwhile, based on the PkM material that had been socialized, the PkM participants understood that the results of phytochemical tests on melinjo leaf Simplicia showed that melinjo leaf extract contains compounds alkaloids, flavonoids, steroids, saponins, and tannins. Meanwhile, the antibacterial test showed that the inhibition zones of various concentrations included a moderate concentration of 40%, a moderate category of 60%, and a strong category of 80%. The average diameter of the inhibition zone increased with each concentration of melinjo leaves.
WORKSHOP FORMULATION OF LIQUID SOAP PREPARATIONS OF CITRUS LEAF EXTRACT PURUT (CITRUS HYSTRIX) AS AN ANTISEPTIC AGAINST STAPHYLOCOCCUS AUREUS BACTERIA: WORKSHOP FORMULATION OF LIQUID SOAP PREPARATIONS OF CITRUS LEAF EXTRACT PURUT (CITRUS HYSTRIX) AS AN ANTISEPTIC AGAINST STAPHYLOCOCCUS AUREUS BACTERIA pratiwi, asti; Siahaan, Safrika Juliana; Pranata, Chandra; Darmirani, Yosi
JURNAL PENGMAS KESTRA (JPK) Vol. 2 No. 2 (2022): Jurnal Pengmas Kestra (JPK)
Publisher : Lembaga Penelitian dan Pengabdian Kepada Masyarakat (LP2M) Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (433.809 KB) | DOI: 10.35451/jpk.v2i2.1454

Abstract

Kaffir lime leaves contain compounds such as flavonoids, saponins, and tannins. Staphylococcus aureus is a pathogenic bacterium associated with virulence. Pharmaceutical preparations used to maintain healthy skin are soaps. The purpose of this study was to determine the inhibitory power of the Liquid Soap Preparation Formulation of Kaffir lime Leaf Extract as an Antiseptic Against Staphylococcus aureus Bacteria. The study was carried out by making ethanol extract of purut orange leaves formulated with liquid soap preparations, then an inhibitory test was carried out on Staphylococcus aureus bacteria that had been bred 3 times with concentrations of 20%, 40%, and 60% and positive and negative controls were carried out. The results of the analysis showed that the formulation of liquid soap preparations of ethanol extract of purut orange leaves with a concentration of 60% has the strongest power against the growth of Staphylococcus aureus bacteria. In conclusion, the concentration of the formulation of liquid soap preparations of ethanol extract of purut orange leaves is directly proportional to the magnitude of the diameter of the inhibitory zone.
Socialization of The Effectiveness Test of Antifungi Formulation of Garlic (Allium Sativum L.) Ethanol Extract Mouth on The Growth of Candida Albicans Pranata, Chandra; Darmirani, Yosi; Pratiwi, Asti; Sumitra, Jhoti
JURNAL PENGMAS KESTRA (JPK) Vol. 3 No. 2 (2023): Jurnal Pengmas Kestra (JPK)
Publisher : Lembaga Penelitian dan Pengabdian Kepada Masyarakat (LP2M) Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jpk.v3i2.1975

Abstract

Garlic plants (Allium sativum L.) can be found in almost all parts of Indonesia, including in Lubuk Pakam, Deli Serdang. The content contained in the ethanol extract of garlic has various secondary metabolites with a role as an antifungal, namely tannins, saponins, flavonoids, and alkaloids. As utilization and information to the public that garlic ethanol extract is made into mouthwash formulations. This article reports on outreach activities to the people of Lubuk Pakam, to be precise in Lubuk Pakam Pekan sub-district about the potential use of natural garlic mouthwash formulations. Testing the antifungal activity of mouthwash preparations was produced by showing the average diameter of inhibition in the form of F1 (12.3 mm), F2 (17.3 mm), F3 (18.5 mm) and F4 (21.6 mm). This means that the higher the concentration, the better the inhibition of garlic ethanol extract in inhibiting fungal growth.
Socialization of The Use of Sisik Naga Leaves (Drymoglossum Piloselloides) Medicinal Plant as An Antibacterial for The Lubuk Pakam Pekan Pranata, Chandra; Wiratma, Dicky Yuswardi; Santika, Rimma
JURNAL PENGMAS KESTRA (JPK) Vol. 4 No. 1 (2024): Jurnal Pengmas Kestra (JPK)
Publisher : Lembaga Penelitian dan Pengabdian Kepada Masyarakat (LP2M) Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jpk.v4i1.2171

Abstract

In Indonesia, one type of plant that is often found is Drymogglossum Piloselloides, or better known as dragon scale leaves. These leaves are included in the category of herbal plants or traditional medicines which are rich in anti-inflammatory, anti-oxidant and anti-cancer compounds. Not only this, secondary metabolite compounds contain various other forms, namely flavonoids, tannins and saponins, which are believed to be antibacterial, to inhibit the growth of bacteria that cause acne, including Staphylococcus epidermidis, which is a member of the genus Gram-positive staphylococcus. In this community service activity, the aim is to provide information about the role and benefits of dragon scale leaves which can be an antibacterial agent for the wider community. In the service program carried out through socialization media using lecture, question and answer and implantation methods with the participation of 15 people in Lubuk Pakam. In accordance with the PkM program that has been produced, a conclusion was obtained regarding wider community insight and knowledge about dragon scale leaves which can be used for antibacterial purposes, in this case proven by the increase in the posttest score which was compared with the pretest score. The average increase in knowledge of PkM participants was obtained with a value of 28.4. Not only that, the maximum posttest score was obtained with a score of 85, in contrast to the lowest posttest score, namely 55 if a comparison was made with the pretest that had been carried out previously.
FORMULASI SEDIAAN MASKER WAJAH MENGGUNAKAN EKSTRAK ETANOL BUNGA KECOMBRANG (ETLINGERA ELATIOR) TERHADAP KELEMBABAN KULIT WAJAH Pranata, Chandra; Boru Situmorang, Novidawati; Marbun, Romauli Anna Teresia
Jurnal FARMASIMED (JFM) Vol 2 No 2 (2020): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v2i2.364

Abstract

ABSTRACT Skin is an essential and vital organ and a reflection of health. Natural antioxidants such as flavonoids, polyphenols and Sapponin are believed to increase moisture on the skin. This ability is the main reason for using Torch Ginger flower extract which is formulated into a form of facial mask in the form of clay facial mask. Objective: To formulate facial moisturizing mask preparations using the extract of Torch Ginger(Etlingera elatior). This study used the Torch Ginger Flower extract facial moisturizing mask formulation method with a concentration of 0 (Blank), 5% and 10%. Evaluation of mask preparations included homogeneity, stability of dosage at temperatures of 80C and 250C, Organoleptic test and pH of preparations. Measurements of skin moisture activity were measured using alar Skin Analyzer which was tested on the face surface 3cm wide. The results showed that the preparation was stable in terms of odor, color and was at a pH of 4.2-6.3 using observations of litmus discoloration. Effectiveness of facial skin moisture with 10% Torch Ginger extract concentration is more effective to produce results at a concentration of 5% and blank. Conclusion: Torch Ginger flower extract can be formulated into preparations of face masks with various concentrations and has the effect of moisturizing the skin and brightening the complexion. Keywords: Torch Ginger Flower Extract, Facial Mask, Clay Facial Mask, Facial Skin Moisture
UJI AKTIVITAS EKSTRAK ETANOL DAUN KARAMUNTING (Rhodomyrtus tomentosa.) TERHADAP PERTUMBUHAN BAKTERI Salmonella thypi Wulandari, Suci; Pranata, Chandra; Sihombing, Yanna Rotua; Nasution, Muhammad Hamim
Jurnal FARMASIMED (JFM) Vol 2 No 2 (2020): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v2i2.382

Abstract

Salmonella thypiis a bacterium that causes typhoid fever. Typhoid fever is an infectious disease that is still a health problem, especially in Indonesia. There are several studies on the types of plants that can control bacterial growth. Indonesian plants are often used as medicine, one of which is the karamunting (Rhodomyrtus tomentosa.). Traditionally a number of parasitic species have been used to prevent and treat various diseases such as cough, anticancer, diuretic, anti-inflammatory, antibacterial, wound or infection karamunting (Rhodomyrtus tomentosa.) Has active compounds such as flavonoids, alkaloids, tannins , saponins, and glycosides which have antibacterial abilities. The purpose of this study is to determine the inhibition of extract of karamunting (Rhodomyrtus tomentosa.) at concentrations of 5%, 10%, and 15%. Test samples using Salmonella thypi. This research is an experimental study with a design (posttest). The research methods included the collection of plant material, determination of plant material, making simplicia, phytochemical screening, making ethanol extract from simplicia by maceration, testing chemical compound groups, and antibacterial testing with paper disk diffusion methods. Karamunting is extracted by maceration process, using 70% ethanol solvent. The results of this study indicate that the benalu coffee leaf extract (Rhodomyrtus tomentosa.) has inhibitory capacity as an antibacterial in Salmonella thypi with a mean inhibition of 16.87 mm at a concentration of 5%, 17.24 mm at a concentration of 10%, and 18.21 mm at a concentration of 15%. The greatest inhibition is produced at a concentration of 15%, because the higher the concentration of the extract, the higher the diameter of the inhibition produced, because the more active substances contained in the extract.
PENGARUH LILIN AROMATERAPI MINYAK LAVENDER (LAVANDULA ANGUSTIFOLIA) TERHADAP KONSENTRASI BELAJAR PADA SISWA MADRASAH TSANAWIYAH AL-WASHLIYAH PASAR MIRING DI DESA PASAR MIRING anggraeni, Ratih; ., Muriati; Pranata, Chandra
Jurnal FARMASIMED (JFM) Vol 3 No 2 (2021): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v3i2.678

Abstract

Aromatherapy is an ancient healing process that uses pure aromatherapy plant extracts aimed at improving the health and well-being of the body, mind and spirit. Lavender contains linalil acetate and linalool. Linalil acetate and linalool have no harmful side effects on health. This substance is antibacterial, fungicidal, viriside, parasiticidal and vermifugal and has neurotonic and uterotonic action. This study aims to determine the effect of lavender oil (Lavandula angustifolia) aromatherapy candles on increasing the concentration of student learning at the Madrasah Tsanawiyah Al-Wasliyah Pasar Miring in Desa Pasar Miring . The study used a quasi-pretest-posttest experimental method for 30 randomly selected students. The instrument in this study used the Army Alpha Test with data analysis using Paired T-Test. Hypothesis testing using Paired T-Test showed p value = 0.026<0.05 (p <0.05). It can be concluded that there is an influence of lavender oil aromatherapy candles on increasing the concentration of student learning in Madrasah Tsanawiyah Al-Wasliyah Pasar Miring in Desa Pasar Miring
UJI AKTIVITAS ANTIBAKTERI EKSTRAK DAUN TALAS (Colococasia Esculenta L.) TERHADAP BAKTERI Escherichia coli Pranata, Chandra; Tarihoran, Sartika Noviani; Darmirani, Yosi
Jurnal FARMASIMED (JFM) Vol 4 No 1 (2021): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v4i1.793

Abstract

Salah satu tanaman yang sering dijadikan obat adalah daun Talas (Colocasia esculanta L.). Daun talas memiliki kandungan senyawa flavonoid, alkaloid, saponin dan tannin yang memiliki kemampuan untuk menghambat pertumbuhan bakteri. Eschericia coli adalah salah satu jenis bakteri yang dapat menyebabkan infeksi pada pencernaan. Salah satu tujuan penelitian ini untuk mengetahui aktivitas antibakteri daun talas dengan konsentrasi yang paling efektif dalam menghambat bakteri Eschericia coli. Penelitian ini adalah penelitian eksperimental murni. Daun talas aktivitas antibakteri dilakukan dengan metode difusi cakram. Penelitian dilakukan dengan 3 variasi konsentrasi yang berbeda. Hasil penelitian menunjukkan bahwa ada aktivitas antibakteri pada setiap konsentrasi. Kesimpulan pemberian aktivitas daun talas dengan konsentrasi 15%, 25%, dan 35% memberikan daya hambat pertumbuhan bakteri paling efektif dengan kosentrasi 25%, 35% yang termasuk dalam kategori kuat. Saran diharapkan kepada peneliti selanjutnya dapat melakukan uji terhadap bakteri lain dan membuat formulasi dari ekstrak daun talas.
TESTING THE EFFECTIVENESS OF FORMULATION OF ANTIFUNCIAL PREPARATION OF GARLIC (ALLIUM SATIVUM L.) ETHANOL EXTRACT MOUNTWASH ON THE GROWTH OF CANDIDA ALBICANS Pranata, Chandra; Sundara, Putri; ., Evi
Jurnal FARMASIMED (JFM) Vol 4 No 2 (2022): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v4i2.1024

Abstract

Telah dilakukan penelitian tentang uji efektivitas formulasi sediaan antifungi obat kumur ekstrak etanol bawang putih (Allium sativum L.) Terhadap pertumbuhan jamur Candida albicans. Ekstrak etanol bawang putih mengandung beberapa senyawa metabolit sekunder, dimana yang berperan sebagai antijamur adalah alkaloid, flavonoid, saponin, dan tanin. Obat kumur ekstrak etanol bawang putih dibuat menjadi lima formula yaitu F0 (basis), F1 (ekstrak etanol bawang putih 15%), F2 (ekstrak etanol bawang putih 25%), F3 (ekstrak etanol bawang putih 50%), dan F4 (ekstrak etanol bawang putih 100%). Evaluasi obat kumur meliputi pemeriksaan Organoleptis, dan Homogenitas. Uji aktivitas antijamur sediaan obat kumur dilakukan dengan metode difusi agar dan dianalisis menggunakan ANOVA satu arah. Hasil evaluasi menunjukkan bahwa sifat fisik sediaan obat kumur memberikan hasil yang baik dan memenuhi syarat sediaan obat kumur. Hasil uji aktivitas antijamur sediaan obat kumur memberikan diameter rata-rata daya hambat sebesar F1 (12,3 mm), F2 (17,3 mm), F3 (18,5 mm) dan F4 (21,6 mm).
EFFECT OF PROCESSING VARIOUS TYPES OF RICE ON CARBOHYDRATE LEVELS Pranata, Chandra; Silalahi, Jansen; ., Yuandani; Cintya, H
Jurnal FARMASIMED (JFM) Vol 5 No 1 (2022): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v5i1.1111

Abstract

Beras adalah salah satu makanan pokok di Indonesia yang mempunyai kandungan karbohidrat yang cukup tinggi antara 70 – 80 %. Zaman sekarang ada berapa cara untuk mengelolah beras menjadi nasi yakni dengan cara kukus dan menggunakan ricecooker. Tujuan dari penelitian ini adalah untuk menetukan kadar karbohidrat pada beras putih, beras merah dan beras hitam sebelum dan sesudah mengalami pengolahan menggunakan metode luff schrool. Berdasarkan hasil pemeriksaan karbohidrat dari beras putih, beras merah dan beras hitam sebelum dan sesudah mengalami pengolahan maka didapatkan hasil pemeriksaan sebelum mengalami pengolahan kadar karbohidrat tertinggi adalah pada beras putih 52,56 ± 0,20 % dan terendah beras hitam 40,47 ± 0,20 %, sedangkan jika dilihat dari cara pengolahan untuk kadar karbohidrat terendah terdapat pada beras hitam kukus dengan kadar 6,00± 0,20% sementara tertinggi pada beras putih ricecooker 14,00 ±1,4 % sehingga didapatkan kesimpulan bahwa adanya pengaruh pengolahan dalam penurunan kadar karbohidrat dalam beras. Kata Kunci: Karbohidrat, Pengolahan, Beras
Co-Authors ., Evi ., Muriati ., Yuandani .S, Aminah Asti Pratiwi Cintya, H Darmirani, Yosi Dicky Yuswardi Wiratma Harahap, Hasni Yaturramadhan Herlina H Jansen Silalahi Limbing, Reida Nasution, Muhammad Hamim Novidawati Boru Situmorang Octora, Debi Dinha Pratiwi, Asti Ramadhani, Lili Ratih Anggraeni Reno Irwanto Renty Monica Samran, Samran Santika, Rimma Siahaan, Safrika Juliana Sihombing, Yanna Rotua Siregar, Riwandi Suci Wulandari Sumardi . sumitra, Jhoti Sundara, Putri Suprianto Suprianto Syarifuddin, Aminah Tarihoran, Sartika Noviani Yana, Sri Nur Yosi Darmirani