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All Journal Jurnal Farmasi Sandi Karsa Jurnal Ilmiah Kesehatan Sandi Husada
Patandung, Gerfan
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Health Professions Library & Information Science Medicine & Pharmacology Nursing Public Health

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Uji Toksisitas Ekstrak Rimpang Temu Hitam (Curcuma aeruginosa Roxb.) Terhadap Larva Udang (Artemia salina Leach) dengan Metode Brine Shrimp Lethality Test (BSLT) Zulfiah, Zulfiah; Megawati, Megawati; Herman, Herman; H. Ambo Lau, Sulfiyana; Hasyim, Muh. Farid; Murniati, Murniati; Roosevelt, Alfreds; Kadang, Yuniharce Kadang; AR, Nurul Izza; Patandung, Gerfan
Jurnal Farmasi Sandi Karsa Vol 6 No 1 (2020): Jurnas Farmasi Sandi Karsa (JFS)
Publisher : Politeknik Sandi Karsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36060/jfs.v6i1.67

Abstract

Penelitian ini bertujuan mengetahui adanya potensi toksisitas dari ekstrak rimpang temu hitam terhadap larva udang Artemia salina Leach dengan metode BSLT. Desain penelitian yang digunakan adalah eksperimental laboratorium yang dilaksanakan di Laboratorium Biologi Sekolah Tinggi Ilmu Farmasi Makassar. Tumbuhan rimpang temu hitam (Curcuma aeruginosa Roxb.) merupakan salah satu tumbuhan yang berada di Indonesia dan memiliki banyak khasiat. Tanaman ini mengandung senyawa alkaloid, saponin, flavonoid dan kurkuminoid. Penelitian ini mengunakan sampel ekstrak etanol, hewan uji yang digunakan berupa Artemia salina Leach yang dibagi dalam 5 kelompok tiap kelompok terdiri dari 10 ekor larva yang dimasukkan kedalam vial. Konsentrasi yang digunakan adalah 20 ppm, 40 ppm, 60 ppm, 80 ppm dan 100 ppm dan terdapat juga kontrol negatif. Pengamatan terhadap larva yang mati dilakukan 24 jam setelah pemberian sampel uji. Data persen kematian larva Artemia salina Leach dibuat persamaan regresi linier dengan membuat persamaan garis lurus yang menghubungkan antara nilai log konsentrasi dan nilai probit. Hasil penelitian bahwa ekstrak etanol rimpang temu hitam memiliki nilai LC50 37,73115 ppm. Pemberian kelima konsentrasi yang berbeda pada penelitian ini menunjukkan potensi toksisitas terhadap larva Artemia salina Leach.
Uji Identifikasi Senyawa Alkaloid Ekstrak Metanol Daun Kelor (Moringa oleifera Lamk) Menggunakan Metode Metode Kromatografi Lapis Tipis Zulfiah, Zulfiah; Herman, Herman; AR., Nurul Izza; Kadang, Yuniharce; Roosevelt, Alfreds; H. Ambo Lau, Sulfiyana; Murniati, Murniati; Hasyim, Muhammad Farid; Megawati, Megawati; Patandung, Gerfan
Jurnal Farmasi Sandi Karsa Vol 6 No 2 (2020): Jurnas Farmasi Sandi Karsa (JFS)
Publisher : Politeknik Sandi Karsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36060/jfs.v6i2.75

Abstract

Penelitian ini adalah hasil observasi laboratorium. Tujuan penelitian ini adalah untuk mengidentifikasi senyawa alkaloid yang terdapat pada daun kelor (Moringa oleifera L.). Identifikasi alkaloid dilakukan dengan metode maserasi dan dilanjutkan dengan metode Kromatografi Lapis Tipis (KLT). Hasil penelitian menunjukan daun kelor positif mengandung senyawa alkaloid. Harga Rf yang didapat 0,8.
Evaluate the Compliance of Diabetes Patients in Taking Medication Diabetes Mellitus in Puskesmas Between Makassar City Zulfiah, Zulfiah; Patandung, Gerfan; Mildawati, Mildawati
Jurnal Farmasi Sandi Karsa Vol 8 No 2 (2022): Jurnal Farmasi Sandi Karsa (JFS)
Publisher : Politeknik Sandi Karsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36060/jfs.v8i2.112

Abstract

Diabetes mellitus is a disease in which the sufferer's body cannot automatically control the level of sugar (glucose) in the blood. In a healthy body, the pancreas releases the hormone insulin, which is responsible for transporting sugar through the blood to the muscles and other tissues to supply energy. Glucose normally circulates in a certain amount in the blood. Glucose is formed in the liver (hepar) from the food consumed. The purpose of this study was to determine the level of adherence of diabetic patients in taking DM medication at the Antara Public Health Center in Makassar City. The method used in this research is descriptive, namely research that includes surveys with data collection techniques in the form of questionnaires. This research was conducted at the Antara Public Health Center, Makassar City. This research was conducted in June 2021 by distributing questionnaires to 58 respondents or the public according to the criteria. The results of this study indicate that the evaluation of diabetes patient compliance in taking diabetes mellitus medication at the Makassar City Public Health Center obtained a percentage of adherence, namely 80.09%, so that it is included in the high compliance level category.
Potensi Hiperglikemia Kombinasi Ekstrak Kulit Buah Semangka (Citrullus lanatus) Dan Ekstrak Kulit Buah Naga Merah (Hylocereus polyrhizus) Edi Kamal, Sainal; Roosevelt, Alfreds; Patandung, Gerfan; Amiruddin, Achmad
Jurnal Farmasi Sandi Karsa Vol 9 No 2 (2023): Jurnal Farmasi Sandi Karsa (JFS)
Publisher : Politeknik Sandi Karsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36060/jfs.v9i2.129

Abstract

This study aims to determine the potential hyperglycemia of the combination of Watermelon Skin Extract (Citrullus lanatus) and Red Dragon Fruit Skin Extract (Hylocereus polyrhizus). The research method used is the alloxane induction method. Rats were divided into 5 groups, namely positive control given metformin 45 mg / Kg BB, negative control given Na. CMC 1% w/v, and variations of test groups given combination extracts with concentration variations of 6% and 13.4%; 9% and 16.4%; and 12% and 19.4% then each group was induced alloxane at a dose of 24 mg / 200g BB. The results of the study on the negative control given NaCMC 1% did not show a decrease in blood sugar levels, in the positive control given metformin 45 mg / KgBB showed an average percent decrease of 94.12%, in the combination extract test group with a dose of 6% and 13.4% showed an average percent decrease of 25.04%; 9% and 16.4% % showed an average percent decrease of 24.69%; and 12% and 19.4% % showed an average percent decrease of 55.61%. Based on the results of this study, a combination extract of 12% and 19.4% can reduce blood sugar levels of white rats. This study proved that red watermelon peel extract and red dragon fruit peel extract have antihyperglycemia effects.
Level of public knowledge on the use of mefenamic acid painkillers Hasyim, Muhammad Farid; Patandung, Gerfan
Jurnal Ilmiah Kesehatan Sandi Husada Vol 14 No 1 (2025): Jurnal Ilmiah Kesehatan Sandi Husada
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat Akademi Keperawatan Sandi Karsa (Merger) Politeknik Sandi Karsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35816/jiskh.v14i1.1256

Abstract

Introduction: Mefenamic acid is a non-steroidal anti-inflammatory drug (NSAID) with analgesic, anti-inflammatory, and antipyretic effects. This medication is used for mild to moderate pain, including headaches, toothaches, postoperative and postpartum pain, dysmenorrhea, and osteoarthritis. This study aims to provide an overview of public knowledge about mefenamic acid pain relievers. Method: This study uses quantitative descriptive research, which conducts direct research on respondents (the community) who are taken as research subjects. This study describes the level of public knowledge about mefenamic acid anti-pain. Results: The most users of mefenamic acid are women, which is 49 people (62.12%), with the most vulnerable age, namely 17-25 years old, as many as 26 people (35.62%), with the most work, which is not working as many as 37 people (50.68%), with the last education of each respondent in high school, which is 35 people (47.95%). Patient knowledge about the use of mefenamic acid reached 75.02%, which was obtained from the processing of data from community research on mefenamic acid, including quite good knowledge. Conclusion: Mefenamic acid is more commonly found in women, especially in young age groups. Most users are unemployed and have a high school-level education background. The level of public knowledge about the use of mefenamic acid is quite good, but further educational efforts are still needed to increase a more comprehensive understanding of the use of the drug. It is recommended that regular counseling be carried out on the appropriate and rational use of drugs, especially for young age groups and people who do not have a background in health education.
Lemongrass oil-based aromatherapy balm innovation for muscle pain reduction and body relaxation Kadang, Yuniharce; Patandung, Gerfan
Jurnal Ilmiah Kesehatan Sandi Husada Vol 14 No 2 (2025): Jurnal Ilmiah Kesehatan Sandi Husada
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat Akademi Keperawatan Sandi Karsa (Merger) Politeknik Sandi Karsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35816/jiskh.v14i2.1316

Abstract

Introduction: Muscle pain is a common condition that affects individuals of various ages due to physical strain, fatigue, or improper posture. Conventional balms often rely on synthetic chemical agents that may cause irritation or excessive heat sensation. Therefore, developing a natural-based topical formulation with dual functions pain reduction and body relaxation has gained growing attention. Lemongrass oil (Cymbopogon citratus) contains active compounds such as citral, geraniol, and limonene, known for their analgesic, anti-inflammatory, and aromatherapeutic properties. This study aimed to innovate an aromatherapy balm using lemongrass essential oil to provide both pain relief and a relaxing effect on the body. Methods: This experimental laboratory study employed a post-test-only design. The balm was formulated with varying concentrations of lemongrass oil (5%, 10%, and 15%), beeswax, vaseline, coconut oil, and menthol. The formulations underwent organoleptic evaluation, skin irritation testing, and effectiveness assessment on mild muscle pain using the Visual Analog Scale (VAS). Ten respondents with muscle discomfort applied the balm twice daily for three days. Data were analyzed descriptively to compare the physical stability, acceptability, and pain reduction effectiveness of each concentration. Results: All formulations demonstrated good physical stability, showing no color or odor alteration after 14 days of storage. Organoleptic evaluation revealed that the 10% lemongrass oil concentration was the most preferred, exhibiting a pleasant aroma and smooth texture. Effectiveness testing indicated that the 10% balm reduced pain intensity by an average of 40%, outperforming the 5% (25%) and 15% (38%) formulations. No cases of skin irritation were reported. Respondents also reported a sense of calmness and relaxation attributed to the aromatherapeutic properties of lemongrass. Conclusion: The aromatherapy balm containing 10% lemongrass oil provides optimal pain relief and relaxation effects without adverse skin reactions. This innovation offers a promising alternative to conventional synthetic balms, aligning with the growing demand for safe, natural, and eco-friendly complementary therapies.
Co-Authors Ali Djamhuri Amiruddin, Achmad Edi Kamal, Sainal Hasyim, Muh. Farid Hasyim, Muhammad Farid Herman Herman Kadang, Yuniharce Kadang, Yuniharce Kadang Megawati - Mildawati Mildawati Nurul Izza AR Roosevelt, Alfreds Sulfiyana H. Ambo Lau Zulfiah, Zulfiah