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UJI IDENTIFIKASI SENYAWA ALKALOID EKSTRAK METANOL DAUN KELOR (Moringa oleifera Lamk) DARI KAB. ENDE NUSA TENGGARA TIMUR SECARA KROMATOGRAFI LAPIS TIPIS AR, Nurul Izza; Kadang, Yuniharce; Permatasari, Arini
Jurnal Farmasi Sandi Karsa Vol 5 No 1 (2019): Jurnal Farmasi Sandi Karsa (JFS)
Publisher : Akademi Farmasi Sandi Karsa

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Telah dilakukan penelitian mengenai Identifikasi senyawa alkaloid daun kelor (Moringa oleifera) yang berasal dari Kab.Ende Provinsi Nusa Tenggara Timur. Penelitian ini adalah hasil observasi laboratorium. Tujuan penelitian ini adalah untuk mengidentifikasi senyawa alkaloid yang terdapat pada daun kelor (Moringa oleifera). Identifikasi alkaloid dilakukan dengan metode maserasi dan dilanjutkan dengan KLT (Kromatografi Lapis Tipis). Hasil penelitian menunjukan daun kelor positif mengandung senyawa alkaloid. Harga Rf yang didapat 0,8.
Uji Efek Antimikroba Infusa Daun Pare (Momordica charantia L.) Terhadap Pertumbuhan Staphylococcus aureus Edi Kamal, Sainal; Megawati, Megawati; H. Ambo Lau, Sulfiyana; Hasyim, Muhammad Farid; Murniati, Murniati; Roosevelt, Alfreds; Kadang, Yuniharce; AR., Nurul Izza; Patandung, Gerfan
Jurnal Farmasi Sandi Karsa Vol 5 No 2 (2019): Jurnal Farmasi Sandi Karsa (JFS)
Publisher : Politeknik Sandi Karsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36060/jfs.v5i2.58

Abstract

Penelitian ini merupakan penelitian eksperimen untuk mengetahui efek antimikroba infus Daun Pare (Momordica charantia L.) terhadap pertumbuhan Staphylococcus aureus. Tujuan dari penelitin ini adalah untuk mengetahui efek antimikroba infus Daun Pare (Momordica charantia L.) terhadap pertumbuhan Staphylococcus aureus. penelitian ini dilakukan di Laboratorium Mikrobiologi Politeknik Kesehatan Makassar. Hasil penelitian menunjukkan bahwa Daun Pare mempunyai efek antimikroba terhadap Staphylococcus aureus yaitu konsentrasi 5% sebesar 10 mm, 10% sebesar 14,66, dan konsentrasi 20% sebesar 19 mm, sedangkan kontrol negatif tidak menimbulkan efek.
Uji Toksisitas Ekstrak Rimpang Temu Hitam (Curcuma aeruginosa Roxb.) Terhadap Larva Udang (Artemia salina Leach) dengan Metode Brine Shrimp Lethality Test (BSLT) Zulfiah, Zulfiah; Megawati, Megawati; Herman, Herman; H. Ambo Lau, Sulfiyana; Hasyim, Muh. Farid; Murniati, Murniati; Roosevelt, Alfreds; Kadang, Yuniharce Kadang; AR, Nurul Izza; Patandung, Gerfan
Jurnal Farmasi Sandi Karsa Vol 6 No 1 (2020): Jurnas Farmasi Sandi Karsa (JFS)
Publisher : Politeknik Sandi Karsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36060/jfs.v6i1.67

Abstract

Penelitian ini bertujuan mengetahui adanya potensi toksisitas dari ekstrak rimpang temu hitam terhadap larva udang Artemia salina Leach dengan metode BSLT. Desain penelitian yang digunakan adalah eksperimental laboratorium yang dilaksanakan di Laboratorium Biologi Sekolah Tinggi Ilmu Farmasi Makassar. Tumbuhan rimpang temu hitam (Curcuma aeruginosa Roxb.) merupakan salah satu tumbuhan yang berada di Indonesia dan memiliki banyak khasiat. Tanaman ini mengandung senyawa alkaloid, saponin, flavonoid dan kurkuminoid. Penelitian ini mengunakan sampel ekstrak etanol, hewan uji yang digunakan berupa Artemia salina Leach yang dibagi dalam 5 kelompok tiap kelompok terdiri dari 10 ekor larva yang dimasukkan kedalam vial. Konsentrasi yang digunakan adalah 20 ppm, 40 ppm, 60 ppm, 80 ppm dan 100 ppm dan terdapat juga kontrol negatif. Pengamatan terhadap larva yang mati dilakukan 24 jam setelah pemberian sampel uji. Data persen kematian larva Artemia salina Leach dibuat persamaan regresi linier dengan membuat persamaan garis lurus yang menghubungkan antara nilai log konsentrasi dan nilai probit. Hasil penelitian bahwa ekstrak etanol rimpang temu hitam memiliki nilai LC50 37,73115 ppm. Pemberian kelima konsentrasi yang berbeda pada penelitian ini menunjukkan potensi toksisitas terhadap larva Artemia salina Leach.
Uji Identifikasi Senyawa Alkaloid Ekstrak Metanol Daun Kelor (Moringa oleifera Lamk) Menggunakan Metode Metode Kromatografi Lapis Tipis Zulfiah, Zulfiah; Herman, Herman; AR., Nurul Izza; Kadang, Yuniharce; Roosevelt, Alfreds; H. Ambo Lau, Sulfiyana; Murniati, Murniati; Hasyim, Muhammad Farid; Megawati, Megawati; Patandung, Gerfan
Jurnal Farmasi Sandi Karsa Vol 6 No 2 (2020): Jurnas Farmasi Sandi Karsa (JFS)
Publisher : Politeknik Sandi Karsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36060/jfs.v6i2.75

Abstract

Penelitian ini adalah hasil observasi laboratorium. Tujuan penelitian ini adalah untuk mengidentifikasi senyawa alkaloid yang terdapat pada daun kelor (Moringa oleifera L.). Identifikasi alkaloid dilakukan dengan metode maserasi dan dilanjutkan dengan metode Kromatografi Lapis Tipis (KLT). Hasil penelitian menunjukan daun kelor positif mengandung senyawa alkaloid. Harga Rf yang didapat 0,8.
Inhibitory Test of Sweet Potato Leaves Infusion (Impomea batatas L.) Toward the Growth of (Propeniumbacterium acnes) Zulfiah Zulfiah; Megawati Megawati; Herman Herman; Sulfiyana H. Ambo Lau; Muhammad Farid Hasyim; Murniati Murniati; Sainal Edi Kamal; Yuniharce Kadang; Nurul Izza AR.; Gerfan Patandung; Alfreds Roosevelt
Jurnal Farmasi Sandi Karsa Vol 7 No 1 (2021): Jurnal Farmasi Sandi Karsa (JFS)
Publisher : Politeknik Sandi Karsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36060/jfs.v7i1.83

Abstract

The research of sweet potato leaf infusion has been done. Based on statistical analysis and discussing of the result of the research. It has been concluded that sweet potato leaves infusion (Ipomoea batatas L.) by using diffusion method, significantly hinder the growth of bacteria (propionibacterium acnes with optimum inhibition zone namely positive control and strong effectiveness. This research was done in july to august 2019 in microbiology laboratories Pharmacy Academy of Sandi Karsa Makassar. The aim of this research is to know the test of sweet potato leaves infusion activities in obstructing the growth of Propionibacterium acnes. The result of this research has shown that the sweet potato leaves infusion Ipomoea batatas) on concentration 5%, 10% and 15% has a zone of inhibition.
FAKTOR YANG BERPENGARUH TERHADAP EDUKASI KERASIONALAN PENGGUNAAN ANTIBIOTIK Izza, Nurul; Farid, Muhammad; Rifai, Muhammad; Kamal, Sainal Edi; Rusli, Rusli
Media Kesehatan Politeknik Kesehatan Makassar Vol 16, No 2 (2021): Media Kesehatan
Publisher : Politeknik Kesehatan Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32382/medkes.v16i2.2294

Abstract

Antibiotik adalah zat kimia yang dihasilkan oleh jamur dan bakteri, yang bersifat mematikan atau menghambat pertumbuhan mikroorganisme lainnya . antibiotik termasuk kedalam golongan obat yang masih sering digunakan karena tingginya penyakit infeksi sehingga berbagai studi menemukan sekitar 40,0-60,4% peresepan antibiotik yang tidak tepat. Tujuan penelitian  adalah menganalisis faktor yang berpengaruh terhadap edukasi kerasionalan penggunaan Antibiotik di Rumah Sakit Sandi Karsa. Metode penelitian ini menggunaan metode cross sectional. Populasi penelitian 150 pasien rawat jalan di RS sandi Karsa, dengan metode random sampling, dengan sampel sebanyak 60 responden yang memetuhi kriteria inklusi dan eksklusi. Data penelitian dianalisis univariat menggunakan persentase frekuensi dan analisis bivariat menerapkan uji Chi-square. Hasil penelitian menunjukkan faktoryang dianalisis yaitu pengetahuan. analisis Chi-square menunjukkan terdapat hubungan pengaruh faktor pengetahuan (ρ=0,022) terhadap edukasi kerasionalan penggunaan Antibiotik di RS Sandi Karsa. Berdasarkan pada hasil penelitian ini dapat disimpulkan bahwa pengetahuan responden merupakan faktor yang berpengaruh terhadap edukasi kerasionalan penggunaan Antibiotik di  Rumah Sakit Sandi Karsa Kata kunci: Antibiotik, Edukasi, Rasional
Formulation of Female Liquid Soap from Leaf Tanjung Extract (Mimusp elengy L) and its effectiveness on Growth of Candida albicans Sulfiyana H. Ambo Lau; Nurul Izza AR; Muh Riswan
Jurnal Farmasi Sandi Karsa Vol 7 No 2 (2021): Jurnas Farmasi Sandi Karsa (JFS)
Publisher : Politeknik Sandi Karsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36060/jfs.v7i2.88

Abstract

This study aims to determine the formulation of Liquid Soap for Women from Tanjung Leaf Extract (Mimusops elengi L) and its effectiveness on the growth of Candida albicans and the most effective concentration. The type of research used is experimental research which is a laboratory study using a simple experimental design, namely the effectiveness of antifungal preparations for female liquid soap extracts from tanjung leaves (Mimusops elengi L) against Candida albicans. This research was conducted in September 2021 at the Laboratory of Pharmaceutical Biology, Pharmaceutical Technology and Pharmacognosy-Phytochemistry of Pharmacy, Sandi Karsa Polytechnic. The results of statistical analysis using the completely randomized design method (ANOVA) showed that giving a negative control of the preparation of female liquid soap with tanjung leaf extract and Resik V liquid soap as a comparison gave a significantly different inhibition zone against Candida albicans, where the inhibition zone showed that the F value of the zone inhibition against Candida albicans was greater than Ftable at the level of 0.05 (3.48) and Ftable at the level of 0.01 (5.99), it can be concluded that the preparation of female cleansing liquid soap from tanjung leaf extract (Mimusops elengi L) concentration 1 % w/v, 3% w/v, and 5% w/v can inhibit Candida albicans.
Description of Poly Pharmacy Prescribed Drug Interactions on One Pharmacy at Bumi Tamalanrea Permai Makassar Megawati, Megawati; AR., Nurul Izza; Wahdini, Wahdini
Jurnal Farmasi Sandi Karsa Vol 8 No 1 (2022): Jurnal Farmasi Sandi Karsa (JFS)
Publisher : Politeknik Sandi Karsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36060/jfs.v8i1.101

Abstract

Research has been carried out on the description of the interaction of prescription drugs in polypharmacy at one of the pharmacies in Bumi Tamalanrea Permai Makassar. The purpose of this study was to determine the description and number of prescription drug interactions in polypharmacy at one of the pharmacies in Bumi Tamalanrea Permai Makassar. This research was conducted descriptively and data collection was carried out prospectively. The results showed that there were 43 prescriptions (out of a total of 284 prescriptions) that had DDI potential, 5 prescriptions that had DDI potential in the major category, 11 prescriptions with moderate DDI potential, 27 recipes with minor DDI potential. The results showed that the potential for DDI that occurred was less than 50%. However, this should receive attention because DDI should not occur in drugs given to patients.
Comparison of The Effectiveness of Cleaning Products Herbal Ingredients Against the Growth of Candida albicans Megawati, Megawati; AR, Nurul Izza; Risqika, Risqika
Jurnal Farmasi Sandi Karsa Vol 8 No 2 (2022): Jurnal Farmasi Sandi Karsa (JFS)
Publisher : Politeknik Sandi Karsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36060/jfs.v8i2.110

Abstract

Leukorrhea is a symptom that arises from vaginitis. This disease is mostly caused by Candida infections, especially Candida albicans. This disease causes an uncomfortable feeling for the sufferer. for that, we need to maintain the balance of the vaginal ecosystem. The aim of the research was to find out the Comparison of the Effectiveness of the Inhibitory Power of Feminine Cleansing Products Made from Herbs on the Growth of Candida albicans. This type of research was carried out experimentally, which is a laboratory study using a simple experimental design. The research was conducted in October 2022 at the Microbiology Laboratory of the Pharmacy Department of the Sandi Karsa Polytechnic Makassar. Based on the results of the research conducted, it can be concluded that the effectiveness of the inhibition of feminine products in Sample I was stronger in inhibiting the growth of Candida albicans compared to Sample II.
An Evaluation of Drug Information Services at the "IAF" Pharmacy in Makassar City Murniati, Murniati; AR, Nurul Izza; Rahmawati, A.
Jurnal Farmasi Sandi Karsa Vol 9 No 1 (2023): Jurnal Farmasi Sandi Karsa (JFS)
Publisher : Politeknik Sandi Karsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36060/jfs.v9i1.117

Abstract

Drug information services are activities carried out by pharmacists in providing impartial drug information, evaluated critically and with the best evidence in all aspects of drug use to other health professionals, patients or the public. Information about drugs including prescription drugs, over-the-counter drugs and herbs. The aim of the research is to find out drug information services at the "IAF" pharmacy in Makassar city. The research method used is a descriptive survey. Sampling in this study by purposive sampling technique. The population in the study were all "IAF" pharmacy staff in May-June 2021. The results showed that the evaluation of drug information services at the "IAF" pharmacy in Makassar city in implementing PERMENKES No.73 of 2016 in drug information services such as answering oral and written questions, providing information and education to patients, providing knowledge and skills to students who are practice, conducting research on drug use and conducting quality assurance programs have been carried out in accordance with PERMENKES No. 73 of 2016 concerning drug information service standards in pharmacies, while making bulletins/brochures/leaflets and writing or presenting papers in scientific forums has not been fully implemented.