Article Per Year (5 Year)
p-Index From 2020 - 2025
0.444
P-Index
This Author published in this journals
All Journal Journal of Social Research Jurnal Kefarmasian Indonesia Indonesian Journal of Pharmacology and Therapy
Sitompul, Fransiska
Unknown Affiliation
Humanities Chemistry Computer Science & IT Economics, Econometrics & Finance Education Immunology & microbiology Medicine & Pharmacology Social Sciences

Published : 3 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 3 Documents
Search

 1 
Evaluasi Penggunaan Antibiotik dengan Metode Gyssens pada Pasien Stroke Rawat Inap di RSUD Koja secara Retrospektif (Periode KJS dan BPJS) Sitompul, Fransiska; Radji, Maksum; Bahtiar, Anton
Jurnal Kefarmasian Indonesia VOLUME 6, NOMOR 1, FEBRUARI 2016
Publisher : Pusat Penelitian dan Pengembangan Biomedis dan Teknologi Dasar Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22435/jki.v6i1.2915

Abstract

Stroke is a major cause of mortality and morbidity worldwide. Patients with stroke are susceptible to medical complications, especially infections. This study aim to evaluate antibiotic by stroke inpatients hospitalized in RSUD Koja (KJS and BPJS period) with Gyssens methods. The study design is a retrospective cross-sectional. The sample is consisted of 112 medical records from KJS period (July 2013-December 2013) and 74 medical records from BPJS period (January 2014-June 2014) taken by total sampling. The use of antibiotic were analyzed using Chi Square and logistic regression multivariate. The percentage of antibiotic use was 23,11%, mostly were ceftriaxon 33,3%, ceftizozim 7,6% and amoxicillin – clavulanic acid 7,6%. Length of stay more than 7 days was 77,96%. The most common route of antibiotic administration was parenteral (68,67%). Patients that were given antibiotics were,among others,diagnosal by bronchopneumonia (29,33%), pulmonary tuberculosis and 17,6% and urinary tract infection (8,7%). The clinical outcome showed that 69,3% of 186 patients were recovered after antibiotic were given to treat their infections. Gyssen evaluation method showed that rational antibiotic used on KJS period was 77,4% and BPJS periods was 81,3%. There were correlations between rational use at antibiotic and the route of administration, between clinical outcome anduse at diagnosis and route of administration. The conclusion of this study according to Gyssen method is the rational antibiotic influence the clinical outcome (p < 0,05)
HISTOPATHOLOGICAL PICTURE OF THE PANCREAS OF MICE (MUS MUSCULUS) DIABETES INDUCED BY STREPTOZOTOCIN-SUKROSA BY GIVING PEPAYA SEED EXTRACT (CARICA PAPAYA L.) Sitompul, Fransiska; Christy, Chatrine Angelica Dwi; Sani, Yulvian; Simatupang, Abraham
Journal of Social Research Vol. 3 No. 3 (2024): Journal of Social Research
Publisher : International Journal Labs

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55324/josr.v3i3.1962

Abstract

This study aimed to investigate the potential of papaya seed extract as an antihyperglycemic agent and to determine the histopathological features of the pancreas of female mice induced by streptozotocin-sucrose. The study used female DDY mice and divided them into five groups, including a negative control group, a positive control group, and three test groups given different doses of papaya seed methanol extract. The parameters measured were the decrease in fasting blood glucose levels, the number, diameter, and area of the islets of Langerhans in each group. The data was analyzed using the one-way ANOVA method with a confidence level of 95% followed by a comparison test using the Least Significant Difference method. The results showed that the methanol extract of papaya seeds has the potential to reduce blood glucose levels and improve the histological structure of the pancreas of diabetic mice induced by streptozotocin-sucrose at an optimum dose of 100 mg/kgBW. There was a significant difference in reducing blood glucose levels between the negative control group and the test group given 100 mg/kgBW papaya seed methanol extract after seven days of treatment. After fourteen days, there was a significant difference between the negative control group and test groups I, II, and III. Although no significant differences were found in the number, diameter, and area of the islets of Langerhans through morphometric photo testing, microscopic photo testing showed that test group I had the best histopathological picture with no vacuolization and necrosis found.
Knowledge of hypertension and its therapy in lay people Simatupang, Abraham; Sitompul, Fransiska; Kurniaty, Linggom; Djojosaputro, Mulyadi; Lumbantobing, Romauli; Silaban, Hertina
Indonesian Journal of Pharmacology and Therapy Vol 3 No 3 (2022)
Publisher : Faculty of Medicine, Public Health, and Nursing Universitas Gadjah Mada and Indonesian Pharmacologist Association or Ikatan Farmakologi Indonesia (IKAFARI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijpther.4468

Abstract

Hypertension is one of the non-communicable diseases that is becoming a global health problem. Hypertension can be identified by systolic blood pressure of 140 mmHg and diastolic 90 mmHg . Uncontrolled hypertension can lead to complications such as stroke, ischemic heart disease, heart attack, heart failure, kidney failure, blindness, etc. According to Basic Health Research 2018 ( Ris et Kesehatan Dasar 2018/Ris kesdas 2018) the prevalence of hypertension for >18 years old wa s 8.4%, and through measurements taken in health care facilities by 34.1%. Prevalence in the city was 34.4%, in the village was 33.7%, while according to gender 31.3% f or male and 36.9% for female. The study aimed to find out the knowledge and awareness of laypeople on hypertension and its therapy. This was a cross-sectional online study with 11 questions. Respondents were recruited from social media groups. The results showed 5 00 respondents (62.8 % female and 37.2 % male) involved in this study . The most common age range was 21-40 years (36.2 %), followed by 41-55 years (38.2%) , and the least was 56-65 years old (18.4%). Seventy-two percent of respondents did not have hypertension, and 9% said they did not know. Fifty-three percent of respondents knew about the value of high blood pressure, and 89% of the respondents said hypertension should be treated regularly. The most hypertension complications answered by respondents were stroke (40%), heart attack (26%) , and heart failure (16%). Amlodipine was the most mentioned by the respondents, and the second was ACE-inhibitor. However, omeprazole and omega-3 were also mentioned as anti-hypertension. Genetic s and a high salt diet were risk factors that many respondents chose. In conclusi on, the r espondents have a good understanding of hypertension. Information related to behaviour is needed to discontinue the increasing prevalence.
Co-Authors Abraham Simatupang Anton Bahtiar Christy, Chatrine Angelica Dwi Kurniaty, Linggom Lumbantobing, Romauli Maksum Radji Mulyadi Djojosaputro, Mulyadi Silaban, Hertina Yulvian Sani