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All Journal El-Hayah : Jurnal Biologi Prosiding Seminar Biologi Biota Es-Syajar:Journal of Islam, Science and Technology Integration
Lil Hanifah
Jurusan Biologi Fakultas Sains Dan Teknologi Universitas Islam Negeri (UIN) Maulana Malik Ibrahim Malang
Religion Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Environmental Science Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Social Sciences

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 1 
Characteristics of Goat Ovarium Granulosa Cells With Extract Leaves ‎‎(Schleichera oleosa) at Different Passage Levels in Vitro Hanifah, Lil; Muti’ah, Roihatul
El-Hayah : Jurnal Biologi Vol 8, No 1 (2020): EL-HAYAH (VOL 8, NO 1 SEPTEMBER 2020)
Publisher : Department of Biology Science and Technology Faculty UIN Maulana Malik Ibrahim Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18860/elha.v8i1.11419

Abstract

S. oleosa belongs to the Sapindaceae family and has phytochemicals phenolic acid so that it has enormous benefits in the process antioxidant. The presence of antioxidant activity in cells can affect the defense of the cell protein membrane, so that the ability of cells to perform division is optimal. In vitro this is mostly done by adding hormones to cell culture media or natural compounds to increase cell proliferation. Every population of cell that has undergone division during the proliferation process to confluent is an indication that the cell is aging. This study was an experimental study was designed using a completely randomized design (CRD) with 5 treatments and 5 replications as follows: K0: granulose cells and culture media without treatment (0 µl), P1: granulose cells and culture media with 1% kesambi leaf extract. (30 µl), P2: granulose cells and culture media given kesambi leaf extract 1.5% (45 µl), P3: granulose cells and culture media given kesambi leaf extract 2% (60 µl) and P4: granulosa cells and The culture media was given 2.5% (75 µl) to the leaves extract., the characteristics of goat ovarian granulosa cells by giving kesambi (Scheichera oleosa) leaf extract at different passages were at the level of confluence showing the highest value in passage I, namely treatment P1. Meanwhile, the level of viability shows the highest value in section I, namely the P4 treatment
Potensi kesambi (Scheichera oleosa) sebagai kandidat imunomodulator Lil Hanifah; Kiptiyah Kiptiyah
Prosiding Seminar Biologi Vol 6 No 1 (2020): PROSIDING SEMINAR NASIONAL BIOLOGI DI ERA PANDEMI COVID-19 (OKTOBER 2020)
Publisher : Jurusan Biologi, Fakultas Sains dan Teknologi, Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/psb.v6i1.15659

Abstract

Setiap orang dihadapkan pada berbagai jenis mikroba di sekitarnya yang setiap saat siap untuk menyerang, tetapi setiap saat tubuh berupaya untuk mempertahankan diri. Salah satu upaya tubuh untuk mempertahankan diri dari berbagai mikroba adalah dengan menyeimbangkan atau mengatur sistem imun yang ada dalam tubuh. Hal ini bisa dilakukan dengan cara penggunaan obat dari bahan alam (tanaman) yang mengandung senyawa aktif tertentu sebagai alternatif pencegahan dari beberapa penyakit. Salah satu tanaman yang mempunyai potensi yang cukup besar untuk dijadikan obat adalah kesambi (Scheichera oleosa). Ekstrak daun kesambi memiliki banyak senyawa aktif di antaranya adalah flavonoid, fenol dan tanin. Senyawa flavonoid diketahui memiliki efek potensial sebagai anti inflamasi dan antioksidan. Senyawa flavonoid seperti flavonols, quercetin dan cathechin terbukti menghambat produksi TNF-α dan nitric oxide oleh lipopolisakarida dari makrofag yang teraktivasi. Supresi TNF-α diduga melalui penghambatan aktivasi NFκB. Penghambatan TNF-α terjadi pada fase post transkripsi sedangkan penghambatan inducible nitric oxide synthase pada fase transkripsi.
The Influence Of Kesambi Leaf Extract (Schleichera oleosa) On Proliferation Granulosa Cell Goat Ovarium (Caprus aegagrus HIRCUS) In Vitro Lil Hanifah
Biota Vol 6 No 1 (2020): Jurnal Biota 2020
Publisher : Faculty of Science and Technology Universitas Islam Negeri Raden Fatah Palembang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19109/Biota.v6i1.4372

Abstract

Kesambi (Schleichera oleosa) belonging to the Sapindaceae family has very important phytochemical elements including terpenoids, falvonoids, phenolic acids, betulins, betulin acids and others, so that they have enormous benefits in the process of antimicrobials, antioxidants, anticancer and can be used for the production of biodiesel. One of the potency of antioxidant ability as an antioxidant is due to its phenolic compounds. The presence of antioxidant activity in cells can affect the defense of cell protein membranes, so that the cell's ability to carry out division is optimal. In vitro this is mostly done by adding hormones to culture cell media or natural compound substances to increase cell proliferation. This study is an experimental study using a Complete Random Design (CRD) with 5 treatments and 4 replications as follows: K0: granulosa cells and culture media without treatment (0 µl), P1: granulosa cells and culture media which were given 1% porch leaf extract (30 µl), P2: granulosa cells and culture media which were given kesambi leaf extract 1.5% (45 µl), P3: granulosa cells and culture media were given 2% (60 µl) kesambi leaf extract and P4: granulosa cells and culture media were given a 2.5% (75 µl) kesambi leaf extract. In this study, there was an influence on the administration of kesambi (Schleichera oleosa) leaf extract to the proliferation of goat ovarian granulosa cells in vitro in the P3 (2%) treatment ie a dose of 60 µl. However, it did not have a significant effect on the viability of goat ovarian granulosa cells.
Potensi Delima (Punica Granatum) dalam Kajian Qur'an dan Sunnah Resmisari, Ruri Siti; Syarifah, Umaiyatus; Holil, Kholifah; Hanifah, Lil
Es-Syajar:Journal of Islam, Science and Technology Integration Vol 2, No 2 (2024): Es-Syajar:Journal of Islam, Science and Technology Integration
Publisher : UNIVERSITAS ISLAM NEGERI MAULANA MALIK IBRAHIM MALANG

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18860/es.v2i2.28599

Abstract

Pomegranate (Punica granatum) occupies a special place in Islamic tradition and modern health literature. This article aims to explore the potential of pomegranate from the perspective of the Qur'an and Sunnah, as well as to examine the health benefits substantiated by scientific research. Pomegranate is mentioned in several verses of the Qur'an, such as in Surah al-An'am (6): 99 and Surah Ar-Rahman (55): 68, highlighting its significance as a symbol of Allah's power. Hadith also recommend the consumption of pomegranate, indicating its spiritual and medicinal properties.Previous research has demonstrated that pomegranate possesses antioxidant and anti-inflammatory properties, and it has the ability to reduce the risk of heart disease and cancer. Studies confirm that pomegranate consumption can mitigate oxidative stress, inflammation, and cancer cell proliferation. This article compiles and analyzes data from various literature sources using a systematic literature review method.The findings of this review indicate that pomegranate has significant religious and health benefits, rendering it an important fruit in a healthy diet and alternative medicine. Further research is necessary to explore the applications of pomegranate in modern health therapies more comprehensively.
Effect of Ethanol Extract from Kepel Leaves (Stelechocarpus burahol (Bl.) Hook F. & Th.) on Confluence and Viability of Primary Mouse (Mus musculus) Neuronal Cells Harjanti, Fitria Nungky; Hanifah, Lil
El-Hayah:Jurnal Biologi Vol 10, No 2 (2025): EL-HAYAH (VOL 10, NO 2 Maret 2025)
Publisher : Program Study of Biology, Science and Technology Faculty, UIN Maulana Malik Ibrahim Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18860/elha.v10i2.28399

Abstract

Kepel (Stelechocarpus Burahol (Bl.) Hook F. Th.), a plant indigenous to Indonesia, is popular for its various benefits, including anti-hyperuricemia, xanthine oxidase inhibition, anti-implantation, anticancer, antiseptic, anti-inflammatory, and antioxidant properties. However, its potential as a neuroprotective agent is not well understood. Therefore, this study aims to investigate the confluence and viability of primary mouse neurons following the administration of ethanol extract from Kepel (Stelechocarpus burahol (Bl.) Hook F. Th.) leaves. Primary neuron cell cultures were divided into four treatment groups: NT (without treatment), T1 (50 µL of Kepel leaf extract), T2 (75 µL of Kepel leaf extract), and T3 (100 µL of Kepel leaf extract). After 48 hours of incubation, culture confluence and viability were assessed. This study approved that the ethanol extract of Kepel leaves did not significantly affect confluence compared to the non-treated group, but cell viability increased when treated with the Kepel leaf extract compared to the non-treated group.
Co-Authors Harjanti, Fitria Nungky Kholifah Holil Kiptiyah, Kiptiyah Roihatul Muti’ah Ruri Siti Resmisari Umaiyatus Syarifah