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Khanifah, Farach
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Efektifitas Kombinasi Ekstrak Buah Pare Dan Sawo Manila Sebagai Antimikroba Bakteri Salmonella Typhi Isolasi Pada Carrier Tifoid Susanto, Awaluddin; Farhan, Antofani; Khanifah, Farach
Journal of Islamic Medicine Vol 5, No 1 (2021): JOURNAL OF ISLAMIC MEDICINE EDISI MARET 2021
Publisher : Faculty of Medicine and Health Science, Universitas Islam Negeri Maulana Malik Ibrahim

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18860/jim.v5i1.11091

Abstract

Latar belakang: Bakteri Salmonella typhi adalah penyebab penyakit demam tifoid. Kasus carrier demam tifoid merupakan faktor resiko terjadinya outbreak demam tifoid. Belum adanya penatalaksanaan pengobatan terhadap carrier inilah yang sekarang masih menjadi permasalahan. Buah pare dan sawo manila terkandung banyak sekali senyawa aktif dan berpotensi sebagai antimikroba alami, salah satunya bakteri Salmonella typhi penyebab demam tifoid. Tujuan: Penelitian ini bertujuan untuk mengetahui kombinasi ekstrak buah sawo manila dan pare yang efektif dalam menghambat pertumbuhan bakteri Salmonella typhi. Metode: Penelitian ini true eksperimental dengan pre-post test group desain control dengan populasi bakteri Salmonella typhi hasil isolasi dari mahasiswa Program Studi Analis Kesehatan STIKes ICMe Jombang yang terdiagnosa carrier demam tifoid. Teknik sampling menggunakan incidental sampling. Pengujian penghambatan pertumbuhan bakteri Salmonella typhi dari carier demam tifoid diberikan ekstrak buah pare dan sawo manila dengan konsentrasi 25%, 50%, 75% dan 100%. Pengukuran jumlah bakteri berasal dari sampel feces carier kemudian ditanam pada media SSA dan dilakukan uji antimikroba metode dilusi padat menggunakan media MHA. Analisa data dengan uji statistik ANOVA menggunakan program SPSS for tingkat kepercayaan p=0,05. Hasil: Hasil penelitian berdasarkan uji Kruskal Wallis menunjukkan perbedaan antar perlakuan secara signifikan (p= 0.018). Kemudian dilakukan uji Mann Withney dengan hasil kelompok perlakuan kontrol berbeda nyata dengan semua kelompok ekstrak, begitu juga antar kelompok perlakuan masing-masing berbeda nyata. Kesimpulan: Berbagai kombinasi konsentrasi ekstrak buah pare dan sawo manila efektif menghambat bakteri Salmonella typhi.Kata kunci : Buah pare , Carrier Tifoid , Ekstrak , Salmonella typhi, Sawo manila,
Pemeriksaan Kecacingan Pada Bayi dan Balita Stunting di Desa Wonosalam Kecamatan Wonosalam Kabupaten Jombang Khanifah, Farach; Sayekti, Sri; Ekowati, Lestari; Kusumawati, Aprilia
Nanggroe: Jurnal Pengabdian Cendikia Vol 2, No 12 (2024): Maret
Publisher : Yayasan Daarul Huda Kruengmane

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.5281/zenodo.10785380

Abstract

Stunting is a condition of growth failure in children (body and brain growth) due to long-term malnutrition so that children are shorter than normal children of their age and experience delays in thinking. The aim of this activity is to identify the number of children with worms and stunting in Wonosalam Village in collaboration with Posyandu Wonosalam. The targets of this examination are stunted babies and toddlers in Wonosalam Village, Wonosalam District, Jombang Regency. The method used is to provide education about worms and stunting, identify data through distributing worm examination questionnaires. From the results of the examination, 54% of babies and toddlers were identified as suffering from worms because the parents' education level did not understand the dangers of worms and stunting, and the parents' work could also have an influence on the occurrence of stunting. In this identification, 14 respondents were identified as suffering from worms and stunting which resulted in growth and development not being the same as children their age. It is hoped that this activity can contribute to improving the health of babies and toddlers, especially regarding the problem of worm infections. It is also necessary to check babies and toddlers who are not stunted for early detection of worms.
Current Study on Antidepresan Activity of Chocolate Drink in Pregnan Woman in Jombang, Indonesia Khanifah, Farach; Mustika Ningrum, Nining; Scheiber, Yasmin Asih
International Journal of Advanced Health Science and Technology Vol. 4 No. 2 (2024): April
Publisher : Forum Ilmiah Teknologi dan Ilmu Kesehatan (FORITIKES)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35882/ijahst.v4i2.218

Abstract

Pregnancy is a natural and physiological process that occurs in every woman. But often pregnant women experience anxiety and worry during pregnancy, this is a normal thing to happen during pregnancy. Symptoms of anxiety during pregnancy vary including anxiety, worry, and anxiety that are difficulty to control, irritability, irritability, difficulty concentrating, body muscles being painful and tense, lack of energy, disturbed sleep patterns, and disturbed rest patterns. Such anxiety can occur during pregnancy in both the I Trimester, II Trimester, and III Trimester. Although anxiety is normal in pregnancy, anxiety symptoms can occur on an ongoing basis if not addressed. The purpose of this study was to analyze the effectiveness of giving chocolate drinks as a complementary therapy to antidepressants in pregnancy. This type of research is quantitative analytics using a Quasi-Experimental research design with one group pre-post test design method using one treatment group. Free variables: Administration of chocolate drinks and bound variables: complementary therapy of antidepressants in pregnancy. The sample in this study was pregnant women who experienced anxiety in pregnancy both mild, moderate, severe, and even panic which matched the inclusion criteria of 124 people. Sampling using purposive sampling techniques. Instrument: HARS (Hamilton Anxiety Rating Scale) and Observation sheet. Data analysis using the Wilcoxon Test. The results showed that the anxiety of pregnant women before being given chocolate drinks was mostly 62.9% experienced mild anxiety, 35.5% experienced moderate anxiety and 1.6% experienced severe anxiety and after being given chocolate drink therapy more than half of the respondents namely 55.6% had no anxiety, 29% had mild anxiety, 15.4% had moderate anxiety and none of the respondents experienced severe anxiety and panic. This study concludes that giving chocolate drinks has activity as an antidepressant in pregnant women. It is hoped that all healthcare providers for pregnant women can recommend complementary therapies with herbal ingredients, especially chocolate as a therapy for reducing anxiety (antidepressants) during pregnancy. So that the benefits of this study can provide a solution for pregnant women who are depressed to use chocolate drinks as an alternative therapy to calm the depressive state.
The lead Gambaran Kadar Timbal (Pb) dalam Darah Petugas Parkir Bank Bumn di Jombang Sebelum dan Setelah Pemberian Vitamin C 75 Mg Per Oral Febiliony, Alvina; Khanifah, Farach; Eka Mildiana, Yana
Jurnal Sintesis: Penelitian Sains, Terapan dan Analisisnya Vol 6 No 1 (2025): Juni 2025
Publisher : Fakultas Sains, Teknologi, dan Analsisi Institut ilmu Kesehatan Bhakti Wiyata

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56399/jst.v6i1.210

Abstract

Asap kendaraan bermotor memberikan sumbangan terbesar dalam polusi udara sebesar 66,34% dari total pencemaran. Asap kendaraan yang mengandung timbal (Pb) dapat menyebabkan gangguan kesehatan ditandai dengan gejala seperti sakit perut, mual, muntah, dan kehilangan berat badan. Salah satu pekerjaan yang beresiko terpapar timbal (Pb) adalah petugas parkir. Faktor resiko paparan timbal salah satunya adalah konsumsi vitamin C. Pemberian vitamin C berfungsi sebagai antioksidan dan pengkelat timbal (Pb) agar dapat diekskresikan melalui urin. Penelitian yang dilakukan bertujuan untuk mengetahui gambaran kadar timbal (Pb) sebelum dan setelah pemberian vitamin C 75 mg pada petugas parkir bank BUMN di Jombang. Penelitian ini bersifat deskriptif, populasi penelitian yaitu petugas parkir bank BUMN di Jombang dengan sampel penelitian yaitu darah petugas parkir bank BUMN di Jombang sebelum dan setelah pemberian vitamin C 75 mg. Teknik sampling yang digunakan yaitu total sampling, dan pada penelitian ini menggunakan uji kuantitatif dengan Spektrofotometri Serapan Atom. Hasil penelitian ini didapatkan sebagian besar responden sebelum pemberian vitamin C 75 mg memiliki kadar timbal (Pb) tidak normal (80%) sedangkan lebih dari setengahnya responden setelah pemberian vitamin C 75 mg memiliki kadar timbal (Pb) tidak normal (70%). Kesimpulannya adalah tidak terdapat penurunan kadar timbal dikarenakan hanya sebagian kecil saja yang mengalami perubahan hasil kadar timbal (Pb). Disarankan untuk peneliti selanjutnya adalah menambahkan dosis dan memperhatikan faktor lainnya yang dapat meningkatkan paparan timbal (Pb).
Pembentukan Kelas Emas (Kelurahan Antistunting Untuk Masyarakat Sehat Sejahtera) Dengan Pemanfaatan Potensi Alam Wonosalam Sebagai Pangan Bergizi Berdaya Dukung e-Complete Untuk Pencapaian SDGS Khanifah, Farach; Sari, Evi Puspita; Srihono, Alex
Nanggroe: Jurnal Pengabdian Cendikia Vol 4, No 4 (2025): July 2025
Publisher : Yayasan Daarul Huda Kruengmane

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.5281/zenodo.16530416

Abstract

Stunting is a chronic nutritional problem which is still one of the major challenges in Panglungan Village, Wonosalam District, Jombang Regency. This community service activity aims to decrease stunting rates through the formation of “Golden Classes” (Antistunting Families for a Healthy Prosperous Society) with an educational approach, health screening, and utilization of local potential in the form of turmeric, kelor, milk and chocolate as functional foods. Activities include extensions on stunting, anemia, and worms; screening hemoglobin levels in adolescents and pregnant mothers; examination of worms in toddlers; manufacturing training of processed nutritious foods (chocolate-chocolate noodles and turmeric-milk ice cream); as well as the development of e-complete educational applications. Results showed a prevalence of anemia of 42.1% in adolescents and 70% in pregnant mothers, as well as a diarrhea rate in toddlers of 26.9%. There was a significant improvement in the knowledge of the participants after the extension. Nutritious food training encourages family self-reliance in nutrition fulfillment as well as opening business opportunities. The e-complete innovation supports continuing education and monitoring of nutrition interventions. This program proves that the integration of educational approaches, technology, and local food utilization can be an effective strategy in the acceleration of stunting decline. 
Pembentukan Kelas Emas (Kelurahan Antistunting Untuk Masyarakat Sehat Sejahtera) Dengan Pemanfaatan Potensi Alam Wonosalam Sebagai Pangan Bergizi Berdaya Dukung e-Complete Untuk Pencapaian SDGS Khanifah, Farach; Sari, Evi Puspita; Srihono, Alex
Nanggroe: Jurnal Pengabdian Cendikia Vol 4, No 4 (2025): July 2025
Publisher : Yayasan Daarul Huda Kruengmane

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.5281/zenodo.16530416

Abstract

Stunting is a chronic nutritional problem which is still one of the major challenges in Panglungan Village, Wonosalam District, Jombang Regency. This community service activity aims to decrease stunting rates through the formation of “Golden Classes” (Antistunting Families for a Healthy Prosperous Society) with an educational approach, health screening, and utilization of local potential in the form of turmeric, kelor, milk and chocolate as functional foods. Activities include extensions on stunting, anemia, and worms; screening hemoglobin levels in adolescents and pregnant mothers; examination of worms in toddlers; manufacturing training of processed nutritious foods (chocolate-chocolate noodles and turmeric-milk ice cream); as well as the development of e-complete educational applications. Results showed a prevalence of anemia of 42.1% in adolescents and 70% in pregnant mothers, as well as a diarrhea rate in toddlers of 26.9%. There was a significant improvement in the knowledge of the participants after the extension. Nutritious food training encourages family self-reliance in nutrition fulfillment as well as opening business opportunities. The e-complete innovation supports continuing education and monitoring of nutrition interventions. This program proves that the integration of educational approaches, technology, and local food utilization can be an effective strategy in the acceleration of stunting decline. 
AKTIVITAS ENZIM Cholinesterase (AChE) PADA KELOMPOK TANI BUMI ASRI DI DUSUN BLAWI DESA SENDANGREJO KECAMATAN NGIMBANG KABUPATEN LAMONGAN Anjarwati, Eryca Dira; Khanifah, Farach; Rosita, Evi
Jurnal Insan Cendekia Vol 12 No 2 (2025): Jurnal Insan Cendekia
Publisher : STIKES Insan Cendekia Medika Jombang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35874/jic.v12i2.1501

Abstract

ABSTRAK Pendahuluan: Pestisida merupakan golongan bahan kimia yang digunakan untuk membasmi hama dan gulma atau tanaman penganggu. Paparan pestisida yang berlebihan pada petani dapat menyebabkan gangguan kesehatan yang ditandai dengan penurunan aktivitas enzim Cholinesterase (AChE), yang berperan penting dalam fungsi sistem saraf. Tujuan: untuk mengetahui aktivitas enzim Cholinesterase (AChE) pada kelompok tani Bumi Asri di Dusun Blawi Desa Sendangrejo Kecamatan Ngimbang Kabupaten Lamongan. Jenis penelitian yang digunakan adalah deskriptif. Populasi penelitian ini merupakan seluruh kelompok tani Bumi Asri di Dusun Blawi Desa Sendangrejo Kecamatan Ngimbang Kabupaten lamongan dengan menggunakan purposive sampling sampel yang digunakan diambil dari anggota kelompok tani "Bumi Asri" sebanyak 10 responden. Data diperoleh melalui kuesioner, dan pemeriksaan aktivitas enzim Cholinesterase (AChE) dalam darah. Metode: Kinetic fotometrik dengan menggunakan alat fotometer. Hasil: Menunjukkan bahwa sebagian besar responden memiliki aktivitas enzim Cholinesterase (AChE) di bawah nilai normal sejumlah 6 responden, yang berkorelasi dengan faktor-faktor seperti usia, lama kerja, durasi penyemprotan, jenis pestisida, dan penggunaan alat pelindung diri (APD). Kesimpulan: Penelitian ini menunjukkan perlunya edukasi dan intervensi terkait bahaya pestisida serta pentingnya penggunaan APD secara konsisten guna meminimalkan risiko keracunan kronis. Diharapkan penelitian ini menjadi dasar bagi pengambilan kebijakan kesehatan kerja di sektor pertanian. ABSTRACT Introduction: Pesticides are a group of chemical substances used to eliminate pests, weeds, or unwanted plants. Excessive exposure to pesticides among farmers can lead to health problems marked by decreased activity of the Cholinesterase enzyme (AChE), which plays a crucial role in nervous system function. Objective: To determine the activity of the Cholinesterase enzyme (AChE) in the Bumi Asri farmer group in Dusun Blawi, Sendangrejo Village, Ngimbang Subdistrict, Lamongan Regency. Method: This research used a descriptive design. The population consisted of all members of the Bumi Asri farmer group in Dusun Blawi. A purposive sampling technique was used to select 10 respondents. Data were collected using questionnaires and blood tests to assess Cholinesterase (AChE) activity, which was measured using a kinetic photometric method with a photometer. Results: The results showed that most respondents (6 out of 10) had Cholinesterase (AChE) enzyme activity below the normal value. This condition correlated with several factors, including age, length of employment, spraying duration, type of pesticide used, and use of personal protective equipment (PPE). Conclusion: This study highlights the need for education and intervention regarding pesticide hazards and the consistent use of PPE to minimize the risk of chronic poisoning. It is hoped that this research can serve as a basis for occupational health policy-making in the agricultural sector.
Co-Authors Anjarwati, Eryca Dira Eka Mildiana, Yana Ekowati, Lestari Farhan, Antofani Febiliony, Alvina Kusumawati, Aprilia Mustika Ningrum, Nining Rosita, Evi Sari, Evi Puspita Scheiber, Yasmin Asih Sri Sayekti Srihono, Alex Susanto, Awaluddin