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Utilization Of Ethanol Extract Of Wungu Leaf (Graptophyllum Pictum (L) Griff) Growing In The Pamah Deli Old Area As An Anti-Inflammatory Meilani, Debi; Miranda, Novia Anisa; Ardiani, Rani; Rahmi, Sofia; Yaturramadhan, Hasni
Indonesian Journal of Science and Pharmacy Vol. 1 No. 2 (2023): Indonesian Journal of Science and Pharmacy
Publisher : Pustaka Media Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63763/ijsp.v1i2.20

Abstract

Wungu leaves (Graptophyllum pictum (L) Griff) are often used as traditional medicine, contain several chemical compounds, including alkaloids, glycosides, steroids, saponins, tannins and flavonoids and chemical compounds, thought to have anti-inflammatory properties. The aim of this study was to utilize the ethanol extract of Wungu leaves that grow in the Pamah Deli Tua area, North Sumatra, as an anti-inflammatory. This study included characterization of simplicia, phytochemical screening and testing of the anti-inflammatory activity of the ethanol extract of Wungu leaves (EEDW). Measurement of rat leg volume induced by 1% λ-carrageenan using a plestimometer, observations were made every 30 minutes for 6 hours. This study used 5 treatment groups, namely group I was given 0.5% CMC suspension, group II was given diclofenac sodium at a dose of 4.5 mg/kg BW, group III was given EEDW at a dose of 100 mg/kg BW, group IV was given EEDW at a dose of 200 mg /kg BW, group V was given EEDW at a dose of 400 mg/kg BW. Inflammation percentage and inflammation inhibition percentage were calculated. Data were analyzed by Duncan to see whether or not there was a difference between the groups. The results showed that there were significant differences between the doses of 100, 200 and 400 mg/kg BW, but between the doses of 400 mg/kh BW and diclofenac sodium there were no significant differences. The percentage of inflammation at a dose of 400 mg/kg BW was 3,366 and the percentage of inflammation inhibition was 86,569%. The higher the dose of EEDW the more effective it is as an anti-inflammatory, and the dose of 400 mg/KgBB in rats is the optimum dose of EEDW as an anti-inflammatory.
SOSIALISASI DALAM UPAYA PENCEGAHAN PENYEBARAN COVID 19 DI AREA MESJID AL-MAHMUDAH Nasution, Nurul Hidayah; Yaturramadhan, Hasni; Angraini, Widya; Yolandi, Silvia
Jurnal Pengabdian Masyarakat Aufa (JPMA) Vol. 2 No. 3 (2020): Vol. 2 No. 3 Desember 2020
Publisher : Universitas Aufa Royhan Di Kota Padangsidipuan

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Abstract

The corona pandemic has currently hit 216 countries. The Task Force for the Acceleration of Handling Covid-19 announced that the total data on the number of positive corona cases in Indonesia until 19 May 2020 were 18,496 people. Governments in both developed and developing countries are still working to stop the spread of this new type of corona virus (SARS-CoV-2). The mosque is one of the places that can be used in an effort to socialize the prevention of the spread of covid-19. The purpose of community service so that the Al-Mahmudah congregation can easily find out information about covid-19 and efforts to prevent the spread of covid-19 in the mosque / mosque area. The socialization was carried out using posters. The population and sample of this service is the congregation of Mesjid Al- Mahmudah with a total of 40 people. The results of this community service were enthusiastically received by the congregation at the Al Mahmudah mosque which can be seen from the many employees who asked about information about efforts to prevent the spread of Covid-19 in the mosque / mosque area as well as efforts to detect, isolate and protect Covid-19 in everyday life. . It is recommended that socialization activities in an effort to prevent the spread of Covid-19 in the Al Mahmudah Mosque Area can be carried out regularly with a more frequent frequency and the range of information dissemination can also be extended to the families of the Al Mahmudah mosque congregation in general so that everyone, family and community will know more, understand more. and can practice efforts to prevent the spread of covid-19 in the mosque / musholla area as well as efforts to detect, isolate and protect Covid-19 in everyday life which can ultimately improve the degree of public health
Pengaruh Ekstrak Etanol Bawang Dayak (Eleutherine Bulbosa (Mill) (Urb) terhadap Kadar Glukosa Darah Tikus Wistar yang Diinduksi Streptozotocin Yaturramadhan, Hasni; Antoni, Adi
Jurnal Kesehatan Ilmiah Aufa Royhan Vol 4 No 1 (2019): Vol.4 No.1 Juni 2019
Publisher : Universitas Aufa Royhan

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Abstract

Dayak onions (Eleutherine bulbosa (Mill) Urb) contain chemical compounds that have the potential to be antidiabetic. The purpose of this study was to examine the effect of ethanol extract of Dayak onion tubers (EEBD) on blood glucose levels of wistar rats induced by streptozotocin. The method of this study was experimental, as many as 30 diabetic rats were divided into 5 groups with one-day treatment for 14 days: glibenclamide 0 , 25 mg / kg, EEBD 125 mg / kg (BD125); 250 mg / kg (BD250); 500 mg / kg (BD500) and CMC 1% bb (CMC) with evaluations including acute fasting blood glucose (KGD) levels. The result of fasting KGD showed a significant decrease after 7 hours of observation (p <0.001). Statistically this decrease was significantly different compared to the negative group (CMC) (p <0.001). Conclusion EEBD can reduce blood glucose levels.
HUBUNGAN KEBIASAAN MEROKOK DENGAN KEJADIAN HIPERTENSI PADA TAHANAN LAKI-LAKI DI LEMBAGA PEMASYARAKATAN PADANGSIDIMPUAN TAHUN 2018 Yaturramadhan, Hasni; Ritonga, Nefonafratilova
Jurnal Kesehatan Ilmiah Aufa Royhan Vol 4 No 1 (2019): Vol.4 No.1 Juni 2019
Publisher : Universitas Aufa Royhan

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Abstract

Hypertension is one of the most common cardiovascular diseases and is the most common in the community. Hypertension is now a major problem for all of us, not only in Indonesia but in the world because hypertension is one of the entry points or risk factors for diseases such as heart disease, kidney failure, diabetes and stroke. Hypertension is also one of the health problems suffered by most of the assisted residents, where the 2011 health data report received by the Directorate General of Corrections shows that heart disease and blood vessels are among the top 10 diseases in prisons and detention centers. The purpose of this study was to determine the relationship between smoking habits and the incidence of hypertension in male prisoners at the Class IIB Prison in Padangsidimpuan City in 2018. The type of research used was quantitative with an analytical survey method through a cross-sectional approach whose population was all elderly male prisoners in LAPAS Padangsidimpuan City in 2018 amounted to 164 and the number of samples was determined by the Slovin formula, where the results were 64 people. Based on the results of the chi square statistical test, it shows that the p value <alpha value (0.05), meaning that H0 is rejected, it can be concluded that there is a relationship between There is a significant difference between smoking habits and the incidence of hypertension in male prisoners in the Class IIB Penitentiary in Padangsidimpuan City in 2018. It is advised that elderly male prisoners are more aware that smoking is a very important risk factor for exposure to hypertension so that respondents have the intention stop smoking. Keywords: Smoking Habits, Incidence of Hypertension, Male Prisoners, LAPAS Padangsidimpuan City
PENGOLAHAN TEH HERBAL DARI DAUN SAWI (Brassica juncea L.) SEBAGAI ALTERNATIF SEDIAAN VITAMIN C yaturramadhan, hasni
Jurnal Kesehatan Ilmiah Aufa Royhan Vol 7 No 2 (2022): Vol. 7 No. 2 Desember 2022
Publisher : Universitas Aufa Royhan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51933/health.v7i2.896

Abstract

Sawi hijau merupakan sayuran kaya akan vitamin dan antioksidan yang bermanfaat bagi kesehatan tubuh. Teh Herbal tidak hanya terbuat dari daun teh, namun juga dapat dari tumbuhan lain yang memiliki manfaat bagi kesehatan seperti pembuatan teh herbal dari daun sawi (Brassica juncea L.). Tujuan penelitian ini adalah pengolahan sediaan teh herbal dari daun sawi yang syarat mutu tehnya sesuai dengan SNI. Metode penelitian ini adalah penelitian eksperimen dengan metode analisa kuantitatif. Hasil penelitian menunjukkan bahwa uji kadar vitamin C W1 sebesar 12,8 % dengan total vitamin C sebanyak 259,5 mg, sedangkan uji kadar vitamin C W2 sebesar 11,2 % dengan total vitamin C sebanyak 160,4 mg. 15 Panelis menyukai produk teh herbal daun sawi dengan formulasi W1.Kesimpulan penelitian ini dimana mengkonsumsi the herbal daun sawi dapat mencukupi kebutuhan vitamin c sehari yang dibutuhkan oleh tubuh Kata kunci :Ekstrak Daun Sawi, Minuman Teh Herbal, Kadar Vitamin C, Sediaan Vitamin C