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All Journal Journal of Dentistry Indonesia Journal of Case Reports in Dental Medicine
Mandasari, Masita
Department Of Oral Medicine, Faculty Of Dentistry, Universitas Indonesia, Jakarta, Indonesia
Dentistry Health Professions

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A Case of Inconspicuous Recurrent Herpes Labialis Mimicking Unilateral Angular Cheilitis Mandasari, Masita; Astuti, Ambar Kusuma; Rahmayanti, Febrina
Journal of Dentistry Indonesia Vol. 25, No. 3
Publisher : UI Scholars Hub

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Abstract

Recurrent herpes labialis (RHL) is a common manifestation of herpes simplex virus (HSV) reactivation in immunocompetent individuals, whereas angular cheilitis is an inflammatory lesion occurring on one or both lip commissures and is induced by local and/or systemic conditions. We describe a case of RHL eruption on the corner of the mouth, easily mistaken as angular cheilitis. Case Report: A 21-year-old male presented to our dental hospital with a 3 day history of a painful, unilateral lesion on the left corner of his mouth. The lesion featured an erythematous base with a yellowish crust that extended outward. We diagnosed the lesion as RHL. We prescribed chlorhexidine solution and topical acyclovir to be applied onto the lesion. At 2 weeks follow-up, the lesion was resolved. An RHL lesion that erupts on the corner of the mouth may initially resemble angular cheilitis. However, the typical clinical presentation, history of recurrence, and the absence of predisposing factors for other lesions suggested an infection caused by HSV. Conclusion: RHL which occurred at one side of the mouth corner can be similar with unilateral AC. But, detailed history taking and clinical observation led to correct diagnosis and management.
Health-Related Anxiety in the Management of Oral Soreness in an HIVSeropositive Patient Mandasari, Masita; Syarif, Zulvia Oktanida; Rahmayanti, Febrina
Journal of Dentistry Indonesia Vol. 27, No. 1
Publisher : UI Scholars Hub

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The number of people living with HIV (PLHIV) has been increasing since the first known case in the early 1980s. However, PLHIV can also experience comorbidities, such as health anxiety. In the oral cavity, anxiety is often associated with the etiology of parafunctional habits. Anxiety can be measured using self-administered instruments, such as the Hospital Anxiety and Depression Scale (HADS) and Short-Health Anxiety Inventory (SHAI), which is specifically used in the medical setting. Objectives: We are describing a case of HIV positive patient with health anxiety who presented to the oral medicine clinic in our hospital with a complaint of discomfort on his lateral sides of the tongue. Case Report: A 35-year-old male patient came to the oral medicine clinic complaining of discomfort on his tongue, which presented for one week. The patient was alarmed by two bumps seen on the right lateral side of his tongue and soreness on the left lateral side. Nystatin oral suspension was prescribed by a medical doctor but discontinued by the patient. The patient was positive for HIV and took ART routinely. Extraoral and intraoral examinations showed unremarkable findings except slightly enlarged and erythematous foliate papillae on the left lateral side of the tongue. The patient was prescribed an antiseptic mouth rinse. After several days, his symptoms had dissipated. Since the patient reported anxiety regarding his health and HIV status, we asked the patient to complete the HADS and SHAI self-assessment tools to measure his level of anxiety. The patient was shown to have anxiety using the SHAI (total score = 21). Conclusion: Health anxiety is a condition that an individual misinterprets as a benign bodily sensation. The management of this type of patient involves addressing the local predisposing factor of the oral complaint and maintaining oral hygiene, followed by an evaluation of health anxiety for the basis of referral to a psychological expert.
Analysis of Bone Destruction Mechanism by Aggregatibacter Actinomycetemcomitans: A Systematic Review Idrus, Erik; Ardiman, Karenina Raihani Amalia; Lestari, Widya; Mandasari, Masita; Soekanto, Sri Angky
Journal of Dentistry Indonesia Vol. 31, No. 2
Publisher : UI Scholars Hub

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Periodontitis is a disease marked by inflammation of the periodontium, caused by biofilms present in the oral cavity, and results in alveolar bone destruction. One of the main hallmarks of periodontitis is the presence of Aggregatibacter actinomycetecomitans, which is generally suppressed by antibiotic administration. The strategy to control A. actinomycetecomitans by small specific peptide inhibitors potentially halts the progression of alveolar bone damage while lowering the risk of antibiotic resistance. The detailed interaction mechanisms of A. actinomycetecomitans and bone cells are fundamental to discovering and constructing the specific inhibitor. Objective : To systematically review the mechanism of bone destruction by A. actinomycetecomitans based on its interaction with bone cells and its precursors. Methods: A comprehensive search was performed in two database (Scopus, PubMed) from September 2021 to June 2022, according to the Preferred Reporting Items for SystematicvReviews and Meta-Analyses (PRISMA) protocol. The terms used in the search were ”Aggregatibacter actinomycetemcomitans” OR “A. actinomycetemcomitans” AN” bone”OR “bone loss” OR “bone destruction” OR “bone resorption” OR “bone formation” OR “bone remodelling” OR “osteclast” OR “osteoblast” OR “osteocyte”. Only articles in English and research articles published within ten years were included. Results: In total, nine articles discussing alveolar bone destruction were included in the review. Most articles reported the virulence of A. actinomycetecomitans, lipopolysaccharide (LPS), and its target cells, osteoclast progenitors, osteoclasts, and osteoblasts. Conclusion: A. actinomycetecomitans induces alveolar bone destruction via various mechanisms, including osteoblast apoptosis, lowering osteoblast differentiation, increasing osteoclast activity and differentiation, and releasing inflammatory cytokines. The detailed interaction mechanisms between A. actinomycetecomitans and bone cells would provide valuable hints for further investigation toward constructing specific inhibitors to disrupt the interaction between A. actinomycetecomitans and bone cells that eventually protect the alveolar bone destruction.
Identification of stress as a predisposing factor in minor recurrent aphthous stomatitis: A case report Samsul, Samsul; Mandasari, Masita; Rahmayanti, Febrina
Journal of Case Reports in Dental Medicine Vol 4, No 3 (2022)
Publisher : Hasanuddin University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20956/jcrdm.v4i3.213

Abstract

Objective: The purpose article is to identify stress predisposing factors in patients with minor RAS.Methods: A 22-year-old woman came to Dental Hospital Faculty of Dentistry UI with complaints of canker sores pain in lower front gums for 4 days ago. Canker sores occur repeatedly every month, especially when there are lots of college assignments. Intraoral examination revealed a single ulcer, clear borders, oval-shape, a pink shallow base surrounded by erythema, size 3x2 mm in attached gingival, region 41-42, with tenderness. Screening for psychological conditions with DASS-21 questionnaire, obtained scores of severe anxiety level and stress. The patient was diagnosed minor RAS with stress predisposing factors.Results: Based on the subjective and objective examinations, the patient was diagnosed with cheilitis and minor RAS with possible predisposing factors to stress and anxiety.Conclusion: Stress can be a predisposing factor for RAS, so managing stress in patient is important for controlling recurrence.
Co-Authors Ambar Kusuma Astuti Ardiman, Karenina Raihani Amalia Erik Idrus Febrina Rahmayanti LESTARI, WIDYA Samsul Samsul Sri Angky Soekanto Syarif, Zulvia Oktanida